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World Renowned Wireless Technology Experts Gathered in KAIST
KAIST hosted the 2015 IEEE WoW from June 5 to 6, 2015 Wireless power transfer technologies, such as wireless electric vehicles, trains and batteries, are increasingly in use. A conference, The 2015 IEEE WoW (Workshop on Wireless Power), was held in KI Building for two days starting June 5, 2015 to exchange ideas on the new trends and issues of the world wireless power technology. The wireless power conference hosted by Institute of Electrical and Electronics Engineers (IEEE), IEEE WoW, was sponsored by its societies, PELS, IAS, IES, VTS, MAG, and PES. This year’s conference took place in Korea for the first time and was titled “IEEE PELS Workshop on Emerging Technologies: Wireless Power.” The event was attended by around 200 experts in wireless power from 15 countries to discuss the international standards and current trends. Keynote speakers were President Don Tan of IEEE; Professor Grant Covic of the University of Auckland; Andrew Daga, the CEO at Momentum Dynamics Corporation; Professor Ron Hui of the City University of Hong Kong; and Jung Goo Cho, the CEO of Green Power Technologies. The forum included plenary speaking sessions on “The Futures of EV and Power Electronics,” “Development of IPT at the University of Auckland,” “Interoperable Solution for Wireless EV Charging,” “Development of IPT for Factory Automation,” “Commercialization of High Power WPT,” and “WPT: From Directional Power to Omni-directional Power.” Notably, KAIST Professor Dong-Ho Cho, responsible for KAIST’s On-Line Electric Vehicle (OLEV) development, spoke on “The Development of Shaped Magnetic Field Systems for EVs and Trains” to introduce the KAIST OLEV bus and OLEV trains developed in cooperation with Korea Railroad Research Institute. The Dialog Sessions on “The Futures of Wireless Electric Vehicles” were led by John M. Miller of JNJ Miller and “Road Charged EV and WPT Regulation and Standard for EV in Japan” by Yoichi Hori of University of Tokyo. The General Chair of this year’s IEEE WoW, KAIST Professor Chun T. Rim said, “This forum serves a great assistance to the industry using wireless power technology in areas such as smartphones, home appliances, Internet of Things, and wearable devices.”
2015.05.29
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Seven Graduates of KAIST S+ Convergence AMP Publish a Book, "The First Penguin"
Seven graduates of KAIST’s S+ Convergence Advanced Management Program (KAMP) have published a book containing their business success stories, The First Penguin, hoping that in telling their story, they will inspire readers who want to become entrepreneurs. The book is available only in Korean. The title of the book refers to a penguin that enters the water first when other penguins hesitate to dive into the ocean, symbolizing the need to make the first move. The book reflects the experiences of the seven authors, for example, how they marched forward with a conviction to an unknown field and succeeded in creating startups. The authors are Sung-Jin Kim, the CEO of i-KAIST; Hyung-Jin Kim, the Chairman and Co-Chief Executive Officer of Sejong Telecom Inc.; Beom-Gu Seo, the CEO of EM Life Science Research Institute; Mi-Sung Seog, the CEO of Luckstone; Jang-won Lee, the CEO of Bluebird Soft; Chung Hee Lee, the CEO of ETRO; and Mi-Oak Jang, the CEO of I Top Asset. The recurring message in the book is “Have strong convictions. Do not give up. Then, you can do it.” The authors hope to give strength and courage to readers in an era of uncertainty and to support those who take challenges to realize their dreams. KAMP will continue to publish their graduates’ stories in an essay format from this year onwards. The program aims to train students to become multidisciplinary future leaders who are able to transcend the borders among business, management, science and technology, and information communications.
2015.05.26
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Professor Duck-Joo Lee Is Elected Vice Chairman of the American Helicopter Society
Professor Duck-Joo Lee of the Department of Aerospace Engineering at KAIST was elected to become the first Korean vice president of the American Helicopter Society (AHS). He will serve a two-year term, starting this July, and his responsibilities will cover Asia, Australia, and Russia. AHS, established in 1943, is the biggest association in the field with 6,800 members. The society is intended to advance helicopter technology and vertical take-off and landing (VTOL) in airplane technology. The AHS’s board of directors consists of thirty experts in rotorcrafts, including the president of Sikorsky Aircraft Corporation, a renowned American helicopter manufacturing company. Professor Lee started his career as a researcher in NASA Ames Research Center in the United States, and is now an acknowledged scholar in the field of aircraft jet engines and helicopter Aero-Acoustics. He also worked as the Assistant Editor-in-Chief of Journal of the American Helicopter Society, the President of the first Asia-Australia Rotorcraft Forum, and the leader of National Task Force Team of Korean Military and Civil Helicopter.
2015.05.18
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Big Data Reveals the Secret of Classical Music Creation
Professor Juyong Park of the Graduate School of Culture Technology at KAIST and his research team have recently published the result of their study (“Topology and Evolution of the Network of Western Classical Music Composers”) on the dynamics of how classical music is created, stylized, and disseminated in EPJ Data Science online on April 22, 2015. For the press release issued by the journal, please go to the link below: EPJ Data Science, May 6, 2015 “EPJ Data Science Highlight—Big Data Reveals Classical Music Creation Secrets” http://www.epj.org/113-epj-ds/941-epjds-highlight-big-data-reveals-classical-music-creation-secrets Researchers used big-data analysis and modelling technique to examine the complex, undercurrent network of classical music composers, which was constructed from the large volume of compact disc (CD) recordings data collected from an online retailer, ArkivMusic, and a music reference website, AllMusicGuide. The study discovered that the basic characteristics of composers’ network are similar to many real-world networks, including the small-world property, the existence of a giant component, high clustering, and heavy-tailed degree distributions. The research team also found that composers collaborated and influenced each other and that composers’ networks grew over time. The research showed that consumers of classical music CDs tend to listen together to the music of a certain group of different composers, offering a useful tool to understand how the music style and market develops. Based on this, the research team predicted the future of the classical music market would be centered on top composers, while maintaining diversity due to the growing number of new composers. Professor Park said, “In recent years, technology greatly affects the way we consume culture and art. Accordingly, we see more and more artists and institutions try to incorporate technology into their creative process, and this will lead us to larger- and higher-quality data that can allow us to learn more about culture and art. The quantitative methodology we have demonstrated in our research will give us an opportunity to explore the nature of art and literature in novel ways.” The European Physical Journal (EPJ) comprises a series of peer-reviewed journals, eleven in total, which cover physics and related subjects such as The Large Hadron Collider, condensed matter, particles, soft matter, and biological physics. The EPJ Data Science is the latest journal launched by EPJ. Figure: Backbone of the Composer Network The composer-composer network backbone, projected from the CD-composer network, reveals the major component of the network. The node sizes represent the composers’ degrees, and the colors represent their active periods.
2015.05.07
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Fast, Accurate 3D Imaging to Track Optically-Trapped Particles
KAIST researchers published an article on the development of a novel technique to precisely track the 3-D positions of optically-trapped particles having complicated geometry in high speed in the April 2015 issue of Optica. Optical tweezers have been used as an invaluable tool for exerting micro-scale force on microscopic particles and manipulating three-dimensional (3-D) positions of particles. Optical tweezers employ a tightly-focused laser whose beam diameter is smaller than one micrometer (1/100 of hair thickness), which generates attractive force on neighboring microscopic particles moving toward the beam focus. Controlling the positions of the beam focus enabled researchers to hold the particles and move them freely to other locations so they coined the name “optical tweezers.” To locate the optically-trapped particles by a laser beam, optical microscopes have usually been employed. Optical microscopes measure light signals scattered by the optically-trapped microscopic particles and the positions of the particles in two dimensions. However, it was difficult to quantify the particles’ precise positions along the optic axis, the direction of the beam, from a single image, which is analogous to the difficulty of determining the front and rear positions of objects when closing an eye due to a lack of depth perception. Furthermore, it became more difficult to measure precisely 3-D positions of particles when scattered light signals were distorted by optically-trapped particles having complicated shapes or other particles occlude the target object along the optic axis. Professor YongKeun Park and his research team in the Department of Physics at the Korea Advanced Institute of Science and Technology (KAIST) employed an optical diffraction tomography (ODT) technique to measure 3-D positions of optically-trapped particles in high speed. The principle of ODT is similar to X-ray CT imaging commonly used in hospitals for visualizing the internal organs of patients. Like X-ray CT imaging, which takes several images from various illumination angles, ODT measures 3-D images of optically-trapped particles by illuminating them with a laser beam in various incidence angles. The KAIST team used optical tweezers to trap a glass bead with a diameter of 2 micrometers, and moved the bead toward a white blood cell having complicated internal structures. The team measured the 3-D dynamics of the white blood cell as it responded to an approaching glass bead via ODT in the high acquisition rate of 60 images per second. Since the white blood cell screens the glass bead along an optic axis, a conventionally-used optical microscope could not determine the 3-D positions of the glass bead. In contrast, the present method employing ODT localized the 3-D positions of the bead precisely as well as measured the composition of the internal materials of the bead and the white blood cell simultaneously. Professor Park said, “Our technique has the advantage of measuring the 3-D positions and internal structures of optically-trapped particles in high speed without labelling exogenous fluorescent agents and can be applied in various fields including physics, optics, nanotechnology, and medical science.” Kyoohyun Kim, the lead author of this paper (“Simultaneous 3D Visualization and Position Tracking of Optically Trapped Particles Using Optical Diffraction Tomography”), added, “This ODT technique can also apply to cellular-level surgeries where optical tweezers are used to manipulate intracellular organelles and to display in real time and in 3-D the images of the reaction of the cell membrane and nucleus during the operation or monitoring the recovery process of the cells from the surgery.” The research results were published as the cover article in the April 2014 issue of Optica, the newest journal launched last year by the Optical Society of America (OSA) for rapid dissemination of high-impact results related to optics. Figure 1: This picture shows the concept image of tweezing an optically-trapped glass bead on the cellular membrane of a white blood cell. Figure 2: High-speed 3-D images produced from optical diffraction tomography technique
2015.04.24
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KAIST and the Naver Corporation Agree to Cooperate in Computer Science
KAIST and Naver, a Korean Internet corporation, concluded a memorandum of understanding (MOU) on April 17, 2015, to cooperate in advancing research and education in computer science. Doo-Hwan Bae (pictured on the right below), the Dean of School of Computing at KAIST and Jong-Mok Park (pictured on left), the Director of Technical Cooperation at Naver, signed the MOU. Under this agreement, the two organizations will foster computer scientists and engineers, conduct joint research projects, and develop training programs for entrepreneurs. KAIST and Naver will organize a steering committee to lay out further details on the agreement.
2015.04.17
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Professor Rim Presents at IAEA Workshop in Vienna
Professor Chun-Taek Rim of the Department of Nuclear and Quantum Engineering at KAIST recently attended the International Atomic Energy Agency (IAEA)’s workshop on the Application of Wireless Technologies in Nuclear Power Plant Instrumentation and Control System. It took place on March 30-April 2, 2015, in Vienna, Austria. Representing Korea, Professor Rim gave a talk entitled “Highly Reliable Wireless Power and Communications under Severe Accident of Nuclear Power Plants (NPPs).” About 20 industry experts from 12 countries such as AREVA (France), Westinghouse (US), Oak Ridge National Laboratory (US), Hitachi (Japan), and ENEA (Italy) joined the meeting. The IAEA hosted the workshop to explore the application of wireless technology for the operation and management of NPPs. It formed a committee consisting of eminent professionals worldwide in NPP instrumentation and control systems, communications, and nuclear power to examine this issue in-depth and to conduct various research projects for the next three years. In particular, the committee will concentrate its research on improving the reliability and safety of using wireless technology, not only in the normal operation of nuclear plants but also in extreme conditions such as the Fukushima Daiichi nuclear accident. The complementation, economic feasibility, and standardization of NPPs when applying wireless technology will be also discussed. Professor Rim currently leads the Nuclear Power Electronics and Robotics Lab at KAIST (http://tesla.kaist.ac.kr/index_eng.php?lag=eng). Picture 1: Professors Rim presents his topic at the IAEA Workshop in Vienna. Picture 2: The IAEA Workshop Participants
2015.04.07
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Anti-Cancer Therapy Delivering Drug to an Entire Tumor Developed
KAIST’s Department of Bio and Brain Engineering Professor Ji-Ho Park and his team successfully developed a new highly efficacious anti-cancer nanotechnology by delivering anti-cancer drugs uniformly to an entire tumor. Their research results were published in Nano Letters online on March 31, 2015. To treat inoperable tumors, anti-cancer medicine is commonly used. However, efficient drug delivery to tumor cells is often difficult, treating an entire tumor with drugs even more so. Using the existing drug delivery systems, including nanotechnology, a drug can be delivered only to tumor cells near blood vessels, leaving cells at the heart of a tumor intact. Since most drugs are injected into the bloodstream, tumor recurrence post medication is frequent. Therefore, the team used liposomes that can fuse to the cell membrane and enter the cell. Once inside liposomes the drug can travel into the bloodstream, enter tumor cells near blood vessels, where they are loaded to exosomes, which are naturally occurring nanoparticles in the body. Since exosomes can travel between cells, the drug can be delivered efficiently into inner cells of the tumor. Exosomes, which are secreted by cells that exist in the tumor microenvironment, is known to have an important role in tumor progression and metastasis since they transfer biological materials between cells. The research team started the investigation recognizing the possibility of delivering the anti-cancer drug to the entire tumor using exosomes. The team injected the light-sensitive anti-cancer drug using their new delivery technique into experimental mice. The researchers applied light to the tumor site to activate the anti-cancer treatment and analyzed a tissue sample. They observed the effects of the anti-cancer drug in the entire tumor tissue. The team’s results establish a ground-breaking foothold in drug delivery technology development that can be tailored to specific diseases by understanding its microenvironment. The work paves the way to more effective drug delivery systems for many chronic diseases, including cancer tumors that were difficult to treat due to the inability to penetrate deep into the tissue. The team is currently conducting experiments with other anti-cancer drugs, which are being developed by pharmaceutical companies, using their tumor-penetrating drug delivery nanotechnology, to identify its effects on malignant tumors. Professor Park said, “This research is the first to apply biological nanoparticles, exosomes that are continuously secreted and can transfer materials to neighboring cells, to deliver drugs directly to the heart of tumor.” Picture: Incorporation of hydrophilic and hydrophobic compounds into membrane vesicles by engineering the parental cells via synthetic liposomes.
2015.04.07
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Novel Photolithographic Technology Enabling 3D Control over Functional Shapes of Microstructures
Professor Shin-Hyun Kim and his research team in the Department of Chemical and Biomolecular Engineering at KAIST have developed a novel photolithographic technology enabling control over the functional shapes of micropatterns using oxygen diffusion. The research was published online in the March 13th issue of Nature Communications and was selected as a featured image for the journal. Photolithography is a standard optical process for transferring micropatterns on to a substrate by exposing specific regions of the photoresist layer to ultraviolet (UV) light. It is used widely throughout industries that require micropatterns, especially in the semiconductor manufacturing industry. Conventional photolithography relied on photomasks which protected certain regions of the substrate from the input UV light. Areas covered by the photomasks remain intact with the base layer while the areas exposed to the UV light are washed away, thus creating a micropattern. This technology was limited to a two-dimensional, disc-shaped design as the boundaries between the exposed and roofed regions are always in a parallel arrangement with the direction of the light. Professor Kim’s research team discovered that: 1) the areas exposed to UV light lowered the concentration of oxygen and thus resulted in oxygen diffusion; and 2) manipulation of the diffusion speed and direction allowed control of the growth, shape and size of the polymers. Based on these findings, the team developed a new photolithographic technology that enabled the production of micropatterns with three-dimensional structures in various shapes and sizes. Oxygen was considered an inhibitor during photopolymerization. Photoresist under UV light creates radicals which initialize a chemical reaction. These radicals are eliminated with the presence of oxygen and thus prevents the reaction. This suggests that the photoresist must be exposed to UV light for an extended time to completely remove oxygen for a chemical reaction to begin. The research team, however, exploited the presence of oxygen. While the region affected by the UV light lowered oxygen concentration, the concentration in the untouched region remained unchanged. This difference in the concentrations caused a diffusion of oxygen to the region under UV light. When the speed of the oxygen flow is slow, the diffusion occurs in parallel with the direction of the UV light. When fast, the diffusion process develops horizontally, outward from the area affected by the UV light. Professor Kim and his team proved this phenomenon both empirically and theoretically. Furthermore, by injecting an external oxygen source, the team was able to manipulate diffusion strength and direction, and thus control the shape and size of the polymer. The use of the polymerization inhibitors enabled and facilitated the fabrication of complex, three-dimensional micropatterns. Professor Kim said, “While 3D printing is considered an innovative manufacturing technology, it cannot be used for mass-production of microscopic products. The new photolithographic technology will have a broad impact on both the academia and industry especially because existing, conventional photolithographic equipment can be used for the development of more complex micropatterns.” His newest technology will enhance the manufacturing process of three-dimensional polymers which were considered difficult to be commercialized. The research was also dedicated to the late Professor Seung-Man Yang of the Department of Chemical and Biomolecular Engineering at KAIST. He was considered one of the greatest scholars in Korea in the field of hydrodynamics and colloids. Picture 1: Featured Image of Nature Communications, March 2015 Picture 2: Polymers with various shapes and sizes produced with the new photolithographic technology developed by Professor Kim
2015.04.06
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Polymers with Highly Improved Light-transformation Efficiency
A joint Korean research team, led by Professor Bum-Joon Kim of the Department of Chemical and Biomolecular Engineering at KAIST and Professor Young-Woo Han of the Department of Nanofusion Engineering at Pusan National University, has developed a new type of electrically-conductive polymer for solar batteries with an improved light-transformation efficiency of up to 5%. The team considers it a viable replacement for existing plastic batteries for solar power which is viewed as the energy source of the future. Polymer solar cells have greater structural stability and heat resistance compared to fullerene organic solar cells. However, they have lower light-transformation efficiency—below 4%—compared to 10% of the latter. The low efficiency is due to the failure of blending among the polymers that compose the active layer of the cell. This phenomenon deters the formation and movement of electrons and thus lowers light-transformation efficiency. By manipulating the structure and concentration of conductive polymers, the team was able to effectively increase the polymer blending and increase light-transformation efficiency. The team was able to maximize the efficiency up to 6% which is the highest reported ratio. Professor Kim said, “This research demonstrates that conductive polymer plastics can be used widely for solar cells and batteries for mobile devices.” The research findings were published in the February 18th issue of the Journal of the American Chemical Society (JACS). Picture: Flexible Solar Cell Polymer Developed by the Research Team
2015.04.05
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Professor Shim Featured with His Drone System in IEEE Spectrum
The IEEE Spectrum, a technology and science magazine published by the Institute of Electrical and Electronics Engineers (IEEE), featured an article of KAIST’s autonomous unmanned aerial vehicles (UAVs) entitled “South Korea Prepares for Drone vs. Drone Combat,” posted on April 1, 2015. The article introduces the anti-drone defense system being developed by Professor “David” Hyunchul Shim of the Department of Aerospace Engineering at KAIST. With the goal of developing guard drones that can detect and capture unknown UAVs, the anti-drone defense system consists of reconnaissance drones, agile multi-rotor UAVs equipped with nets which are dropped to snare enemy drones, and transport UAVs to carry smaller drones. Professor Shim currently leads KAIST’s Unmanned System Research Group (USRG, http://unmanned.kaist.ac.kr/) and Center of Field Robotics for Innovation, Exploration, aNd Defense (C-FRIEND). For the article, please go to http://spectrum.ieee.org/automaton/robotics/aerial-robots/south-korea-drone-vs-drone.
2015.04.02
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Mystery in Membrane Traffic How NSF Disassembles Single SNAR Complex Solved
KAIST researchers discovered that the protein N-ethylmaleimide-sensitive factor (NSF) unravels a single SNARE complex using one round ATP turnover by tearing the complex with a single burst, contradicting a previous theory that it unwinds in a processive manner. In 2013, James E. Rothman, Randy W. Schekman, and Thomas C. Südhof won the Nobel Prize in Physiology or Medicine for their discoveries of molecular machineries for vesicle trafficking, a major transport system in cells for maintaining cellular processes. Vesicle traffic acts as a kind of “home-delivery service” in cells. Vesicles package and deliver materials such as proteins and hormones from one cell organelle to another. Then it releases its contents by fusing with the target organelle’s membrane. One example of vesicle traffic is in neuronal communications, where neurotransmitters are released from a neuron. Some of the key proteins for vesicle traffic discovered by the Nobel Prize winners were N-ethylmaleimide-sensitive factor (NSF), alpha-soluble NSF attachment protein (α-SNAP), and soluble SNAP receptors (SNAREs). SNARE proteins are known as the minimal machinery for membrane fusion. To induce membrane fusion, the proteins combine to form a SNARE complex in a four helical bundle, and NSF and α-SNAP disassemble the SNARE complex for reuse. In particular, NSF can bind an energy source molecule, adenosine triphosphate (ATP), and the ATP-bound NSF develops internal tension via cleavage of ATP. This process is used to exert great force on SNARE complexes, eventually pulling them apart. However, although about 30 years have passed since the Nobel Prize winners’ discovery, how NSF/α-SNAP disassembled the SNARE complex remained a mystery to scientists due to a lack in methodology. In a recent issue of Science, published on March 27, 2015, a research team, led by Tae-Young Yoon of the Department of Physics at the Korea Advanced Institute of Science and Technology (KAIST) and Reinhard Jahn of the Department of Neurobiology of the Max-Planck-Institute for Biophysical Chemistry, reports that NSF/α-SNAP disassemble a single SNARE complex using various single-molecule biophysical methods that allow them to monitor and manipulate individual protein complexes. “We have learned that NSF releases energy in a burst within 20 milliseconds to “tear” the SNARE complex apart in a one-step global unfolding reaction, which is immediately followed by the release of SNARE proteins,” said Yoon. Previously, it was believed that NSF disassembled a SNARE complex by unwinding it in a processive manner. Also, largely unexplained was how many cycles of ATP hydrolysis were required and how these cycles were connected to the disassembly of the SNARE complex. Yoon added, “From our research, we found that NSF requires hydrolysis of ATPs that were already bound before it attached to the SNAREs—which means that only one round of an ATP turnover is sufficient for SNARE complex disassembly. Moreover, this is possible because NSF pulls a SNARE complex apart by building up the energy from individual ATPs and releasing it at once, yielding a “spring-loaded” mechanism.” NSF is a member of the ATPases associated with various cellular activities family (AAA+ ATPase), which is essential for many cellular functions such as DNA replication and protein degradation, membrane fusion, microtubule severing, peroxisome biogenesis, signal transduction, and the regulation of gene expression. This research has added valuable new insights and hints for studying AAA+ ATPase proteins, which are crucial for various living beings. The title of the research paper is “Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover.” (DOI: 10.1126/science.aaa5267) Youtube Link: https://www.youtube.com/watch?v=FqTSYHtyHWE&feature=youtu.be Picture 1. Working model of how NSF/α-SNAP disassemble a single SNARE complex Picture 2. After neurotransmitter release, NSF disassembles a single SNARE complex using a single round of ATP turnover in a single burst reaction.
2015.03.28
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