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Dr.M Drives Smart Healthcare Industry in Partnership with Hancom
President Sung-Mo Kang signed an agreement on January 25 with Hancom Group Chairman Sang Chul Kim to establish a smart healthcare complex in Gapyeong, Kyonggido. With the Gapyeong complex launch, KAIST will come to commercialize Dr. M system along with other Dr.M consortium members as a new growth engine to drive the smart health industry.
Dr. M is a smart healthcare platform developed by the Health Science Research Institute at KAIST in 2014. Dr. M is capable of analyzing and predicting diseases, as well as prescribing, by incorporating ICT and medical technologies. Dr. M applies diverse technologies such as healthcare sensors, wearable devices, low-power communications technology, and cloud and big data collection platforms.
Hancom Group, a leading computer software company in Korea, has participated in the project since 2015 for advancing the smart healthcare market by developing mobile healthcare software program. Hancom joined the Dr.M consortium launched last November.
(President Kang (left) poses with Hancom Chairman Kim after signing.)
2017.02.03 View 5647 -
KAIST Intensive Science Camp for Middle-High School Students
The KAIST Global Institute of Talented Education (Director: Dong-Soo Kwon) invited around 90 middle and high school students for an advanced science intensive camp from January 22 to 24.
This camp targeted middle and high school students in community centers or child-care institutions. It aims to increase students’ interest in science and engineering, and assist them with their career paths through programs such as special lectures on science, advanced science projects, and career mentoring.
Participating students were divided into groups of seven or eight with a KAIST student as a mentor to conduct advanced science projects such as VR controller production and robot arm programming. The camp included exploring future career options and science and engineering college admission counselling.
Jiyoung Ryu, Research Professor for the KAIST Global Institute of Talented Education, said, “KAIST started the science and engineering career experience program in 2016 with the Ministry of Education and Korea Research Institute for Vocational Education and Training (KRIVET). So far, 6000 middle and high school students from around the country have participated. The camp is more meaningful since it educates students in social responsibility, in addition to the fields of science and engineering, both of which are missions and goals that KAIST strives for.” She continued to say, “We plan to continue to expand the program in the future.”
The KAIST Global Institute of Talented Education is actively conducting research and projects on national education for talented youth such as policy research concerning gifted education, science and engineering career education, advanced science camps, training for gifted education teachers, and cyber gifted education programs.
2017.02.01 View 7026 -
JETS Conference 2017
KAIST and four science and technology research universities in Korea co-hosted a technology start-up fair, the 2017 JETS (Job, Exhibition, Tech Forum, and Startup) Conference January 19 ~20 in the Ryu Geun-chul Sports Complex at KAIST.
Korea’s major science and technology research universities, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Gwangju Institute of Science and Technology (GIST), Pohang University of Science and Technology (Postech), and Ulsan National Institute of Science and Technology (UNIST), held the event in a collaborative effort to educate, inspire, and connect young entrepreneurs, especially those who will launch technology start-ups.
The conference brought entrepreneurs and innovators together who seek ways of working with and supporting start-ups and for their sustainable growth. It also drew aspiring young students and researchers from universities and the government-funded research institutions who are in the process of commercializing their technology. Students from each university’s industry-academia cooperation program who incubated their technology and ideas were key contributors.
At the Tech Forum, entrepreneurship and technology consultation specialists including Joe Jasin, managing director at DNA Investment Partners in the US, the founder of Cyworld Dong-Hyung Lee, and Professor Hawoong Jeong, a complex bio-network specialist from the Department of Physics of KAIST lectured on the ecosystem of start-ups and its trends and development.
The Dean of University-Industry Cooperation at KAIST Joongmyeon Bae said, "We organized this event in collaboration with four major research universities to further encourage technology start-ups from young students and help their ideas and technology bear fruit. We will continue to strive to create an ecosystem of start-ups which works efficiently.”
(Above photo: Founder of the Cyworld, Dong-Hyung Lee gives a lecture at the Tech Forum. Below photo: Students visit exhibition booth of each participating institution.)
2017.01.20 View 10139 -
Science, IT & Culture Volunteering Team at Cambodia
The Science, IT and Culture Volunteering Team, which is composed of 17 undergraduates, is visiting Cambodia January 1 to 16. Based at Hosanna High School in Phnom Penh, the KAIST volunteering team will participate in diverse science and IT classes as well as cultural events for Cambodian high school students.
The KAIST volunteering service is designed to improve Cambodian students’ science education including the areas of physics, chemistry, biology, earth science, as well as an increased exposure to IT technologies. For this service, the volunteering team has prepared for three months, making syllabi for the science classes in addition to planning Arduino IT classes and cultural performances, including K-pop dances and Korean traditional games.
The team will present various science experiments including smart electric fan and mini vehicles using Arduino. Before departing, the students made great efforts to ensure this service would be a success by taking a basic Khmer language class and studying safety education.
Se-Woong Oh, the head of the team said, "All our members are very excited to have the chance to share our knowledge with Cambodian students and help them learn science and IT technology. We hope this service will serve as an opportunity to understand a different culture as well. We made every effort to prepare for an activity we believe in."
(KAIST volunteer team with Hosanna High School students in Phnom Penh, Cambodia.)
2017.01.10 View 4394 -
Nobel Laureate Dr. John Michael Kosterlitz Speaks at KAIST
KAIST’s Department of Physics will invite one of three co-recipients of the Nobel Prize in Physics 2016, Professor John Michael Kosterlitz of Brown University, on January 9, 2017, to speak about the exotic states of matter, which is entitled “Topological Defects and Phase Transitions.”
Professor Kosterlitz shares the Nobel award with two other researchers, David Thouless and Duncan Haldane. He is considered one of the pioneers in the field of topological phases. In the early 1970s, along with Thouless, he demonstrated that superconductivity could occur at low temperatures and explained the mechanism behind, phase transition, that makes superconductivity disappear at higher temperatures.
Over the last decade, topological materials and their applications have been widely studied with the hope of using them in new generations of electronics and superconductors, or in future quantum computers. Details of the lecture follow below:
Distinguished Lecture Series by KAIST’s Physics Department
· Speaker: Professor John Michael Kosterlitz of the Physics Department,
Brown University
· Topic: “Topological Defects and Phase Transitions”
· Date: January 9, 2017, 4:00 PM
· Place: Lecture Hall (#1501), College of Natural Sciences (E6-2)
2017.01.06 View 6355 -
KAIST Undergraduates Win the Innovative Design Contest 2016
A team of KAIST students, consisting of five undergraduates (Do-Hoon Kwon, Tae-Hyun Kim, Hak-Gi Do, Hyun-Joo Lee, and Jong-Ho Jeong) from the Department of Mechanical Engineering, won the grand prize at the Innovative Design Contest held at Osaka University in Japan on December 12-13, 2016. The event took place during the 16th Asia Design Engineering Workshop (A-DEWS).
For this year’s contest, a total of ten student teams from such countries as Korea, Japan, Taiwan, and Malaysia participated, and Team KAIST earned the highest scores. The five KAIST students, all taking the course entitled “Production of Creative Systems,” developed a manual wheelchair accessory called “Safe Attachable Wheelchair Assistive Device in Capstone Design (SAWADiCap).
SAWADiCap is a detachable auxiliary power device that increases the range and mobility of manual wheelchairs. The device can easily be installed and removed, compared to existing add-on attachments for wheelchairs. Users can also enjoy similar advantages offered by powered wheelchairs at a lower cost. In their presentation on the device, the KAIST students introduced their design to improve the power of manual wheelchairs employing the magnetic reinforcement effect and to include the safety features necessary for users to install or operate the device.
Do-Hoon Kwon said, “Our team had a great experience participating in the contest—we met people with diverse backgrounds and expanded our understanding in the field.”
Professor Seibum B. Choi of the Mechanical Engineering Department, who advises the KAIST team, added, “I hope our technology can help the spread of affordable wheelchairs and increase mobility for the disabled.”
Established in 2000, A-DEWS is held annually by the Asian branch of the Design Engineering Workshop to provide an international forum for researchers and practitioners in the field of design engineering by facilitating the exchange of recent research results and sharing knowledge about design strategies and methods. This year’s theme for the workshop was “Innovation of Life.”
A-DEWS hosts the Innovative Design Contest to encourage young engineers, researchers, and students who are creating innovative products, services, and product-services and to show appreciation for their efforts.
Pictured below from left to right are Hyun-Joo Lee, Do-Hoon Kwon, Jong-Ho Jeong, and Hak-Gi Do.
2017.01.03 View 8206 -
KAIST Ph.D. Candidate Wins the Next Generation of Engineers Award
Joo-Sung Kim, a doctoral student at the EEWS (Environment, Energy, Water and Sustainability) Graduate School won the inaugural Next Generation of Engineers Award in Leadership on December 14, 2016.
The National Academy of Engineering of Korea hosts this award to support creative and ambitious students who have the potential to become leaders in engineering and who will serve as role models for future Korean engineers. Based on the recommendations of university professors in engineering and members of the academy, seven students are selected for the award in the categories of leadership and entrepreneurship.
With his research focus on the development of high-performance, next-generation secondary cells for wearable devices such as smart watches, health bands, and smart eyewear, Joo-Sung created a startup, Lithium-ion Battery Energy Science and Technology (LiBEST), Inc. He plans to base his company at the Office of University and Industry Cooperation, KAIST, where he can receive assistance for launching the mass-production system for his technology.
His adviser, Professor Jang-Wook Choi of the EEWS Graduate School, noted, “Joo-Sung has been a great student who has a strong sense of curiosity and perseverance. The award is the by-product of his hard work.”
“I have always enjoyed my work and study as a researcher, but eventually would like to expand my career into business based on the results of my research. It would be wonderful if I could become a businessman like Elon Musk, Masayoshi Son, or Ma Yun and create a role model for aspiring engineers in Korea by combining science and technology with business demand to create social values that benefit many people,” Joo-Young said.
2016.12.26 View 8903 -
EEWS Graduate School Team Receives the S-Oil Best Paper Award
Professor Hyungjun Kim and Dr. He-Young Shin from the EEWS (Energy, Environment, Water and Sustainability) Graduate School at KAIST received the Best Paper Award in Chemistry from S-Oil, a Korean petroleum and refinery company, on November 29, 2016.
Established in 2011, the S-Oil Best Paper Awards are bestowed annually upon ten young scientists in the fields of five basic sciences: mathematics, physics, chemistry, biology, and earth science. The scientists are selected at the recommendation of the Korean Academy of Science and Technology and the Association of Korean Universities. The awards grant a total of USD 230,000 for research funding.
Dr. Shin, the lead author of the awarded research paper, said, “My research interest has been catalyst studies based on theoretical chemistry. I am pleased to accept this award that will support my studies, and will continue to research catalyst design that can predict parameters and integrate them into catalytic systems.”
Professor Hyungjun Kim (left) and Dr. He-Young Shin (right)
2016.12.23 View 8374 -
The Antibody That Normalizes Tumor Vessels
Researchers also discover that their antisepsis antibody reduces glioma, lung and breast cancer progression in mice.
A research team at the Center for Vascular Research within the Institute for Basic Science (IBS) discovered that the antisepsis antibody ABTAA (Ang2-Binding and Tie2-Activating Antibody) reduces tumor volume and improves the delivery of anti-cancer drugs. Published in Cancer Cell, this study demonstrates that ABTAA restores the structural and functional integrity of tumor blood vessels in three different tumor models: breast, lungs, and brain.
Blood vessels inside and around an established tumor can be described as a chaotic and dysfunctional labyrinth. While the inner walls of healthy blood vessels are surrounded and supported by endothelial cells and other cells called pericytes, in the established tumor, the endothelial junctions are broken apart and pericytes are also detached. Blood flow into and from the tumor is severely retarded and tumor vessels lacking an intact vessel wall become leaky. This microenvironment causes limited drug delivery to the tumor and leads to inadequate oxygen supply (hypoxia) and even metastasis.
The research team led by Professor Gou-Young Koh at KAIST’s Graduate School of Medical Science and Engineering found that the antibody ABTAA normalizes the tumor vessels and hence, change the whole tumor microenvironment. “We call it normalization of tumor vessels, because it resembles closely the wall architecture of healthy, normal vessels,” explains PARK Jin-Sung, first author of the study. And continues: “Tumor can adapt to hypoxia and get more aggressive, so we tried to prevent this transition by normalizing tumor vessels. ABTAA changes the whole tumor environment, oxygenation status and level of lactate, so that the immune cells and drugs can reach the core regions of the tumor more easily. In this way, we create a favorable ground for tumor treatment.”
In an attempt to generate antibodies targeting the protein Ang2, which is specifically expressed by endothelial cells in stressful conditions like in tumor, the team unexpectedly discovered that ABTAA has a peculiar way of working and a dual function. ABTAA indeed not only blocks Ang2, but also activates Tie2 at the same time. Tie2 is a receptor present on the cell membrane of endothelial cells. ABTAA causes Ang2 to cluster together and to strongly activate Tie2 receptors. “If we activate Tie2, we can efficiently normalize tumor vessels, enhance drug delivery and change the whole microenvironment,” explains KOH Gou Young, Director of the Center for Vascular Research.
Several pharmaceutical companies are developing Ang2-blocking antibodies to cure cancer. However, even if these antibodies significantly inhibit tumor progression, they do not stop tumor hypoxia. Moreover, most of the anti-cancer drugs target the tumor at its early stage, when tumors are still hard to diagnose. ABTAA, instead, works with tumors that are already rooted: “When the tumor is established, hypoxia is the main driver of tumor progression. So, if we eliminate hypoxia, we make the tumor milder, by reducing its progression and metastasis,” comments Koh.
Figure: Schematic drawing of a blood vessel around tumors before and after treatment with ABTAA. The picture above shows a typical tumor vasculature characterized by damaged walls, red blood cells leakage and detached pericytes. Activating Tie2 on endothelial cells with the antibody ABTAA restores the normal vessel architecture: endothelial and pericytes on the vessel walls are stabilized, the delivery of blood is improved, and the anticancer drugs are more likely to reach the tumor core.
The researchers tested ABTAA in mice with three different types of tumors that show high levels of Ang2: glioma (a type of a brain tumor), lung carcinoma, and breast cancer. They also compared the effect of ABTAA with ABA, another antibody that blocks Ang2 but misses the Tie2 activating properties. In all three cases, ABTAA was superior to ABA in inducing tumor vessel normalization, which led to a better delivery of the anti-cancer drugs into the tumor core region.
Glioma is one of the so-called intractable diseases, because of its poor prognosis and treatment. Professor Koh’s team found that the glioma volume was reduced 39% by ABTAA and 17% by ABA. ABTAA profoundly reduced vascular leakage and edema formation in glioma through promoting vascular tightening. Moreover, when ABTAA was administered together with the chemotherapeutic drug temozolomide (TMZ), the tumor volume reduces further (76% by ABTAA+TMZ, 51% by ABA+TMZ, and 36% by TMZ).
In the Lewis Lung Carcinoma (LLC) tumor model, the team administered ABTAA together with a chemotherapeutic drug called cisplatin (Cpt) and observed a greater suppression of tumor growth (52%) compared with the controls and increased overall survival. Moreover, ABTAA+Cpt led to a marked increase in necrotic area within tumors.
Finally, in a spontaneous breast cancer model, ABTAA delayed tumor growth and enhanced the anti-tumor effect of Cpt.
Courtesy of the Institute for Basic Sciences (IBS)
Figure: The antibody ABTAA alone and in combination with other anti-cancer drugs have a beneficial effect in reducing tumor volume. ABTAA was tested in mice with brain tumor (glioma), lung or breast cancer. The image shows the improvements: reduction in glioma tumor size, reduction in metastatic colonies in lung tumor and decrease in necrotic regions in breast tumor.
In the future, the team would like to further understand the underlying relationship between faulty blood vessels and diseases. “We would like to apply this antibody to an organ that is rich in blood vessels, that is the eye, and see if this antibody can be useful to treat eye diseases such as age-related macular degeneration and diabetic retinopathy,” concludes Koh.
Professor Gou-Young Koh (left) and Jin-Sung Park (right)
2016.12.16 View 8243 -
Professor Ih Reappointed as Vice President of the ICA
Professor Jeong-Guon Ih of the Mechanical Engineering Department at KAIST has been re-elected as the Vice President of the International Commission for Acoustics (ICA). His second term of office is from October 16, 2016 to September 30, 2019.
Professor Ih, the first Korean who was selected to a senior position on the ICA management board, took over his current post in 2015 when the vice president at the time passed away in the middle of his term.
During his stint, Professor Ih played a key role in planning the ICA’s triennial gathering, the International Congress on Acoustics, in Gyeongju, Korea, scheduled for October 24-28, 2022. He will also serve as the general chair for the conference.
The International Congress on Acoustics is the largest professional meeting in the field of acoustics. It provides a venue to meet, discuss, and exchange ideas covering all aspects of acoustics including an extensive technical exhibition that highlights the latest advances in acoustical products such as materials, systems, and equipment.
Acoustics has grown to become an important element in the Information Age in the areas of automation, machine learning, and virtual reality. Hosting the Congress will support Korea’s goal to lead acoustic research and development on the global stage.
Professor Ih said, “Serving international academic organizations offers great opportunities to learn global trends and to collaborate with various research institutions, universities, and industries worldwide. I hope my service will inspire many young Korean researchers to pursue their careers in this field.”
Professor Ih is also a member of eight eminent international academic societies such as the Audio Engineering Society, the International Congress on Ultrasonics, and the International Institute of Noise Control Engineering.
The ICA was founded in 1951 as a subcommittee of the International Union of Pure and Applied Physics (IUPAP), and it consists of 46 member states and four observer nations. It promotes international development and collaboration in all fields of acoustics including research, development, education, and standardization.
2016.12.16 View 6004 -
A KAIST Team Wins the Chem-E-Car Competition 2016
A KAIST team consisted of four students from the Department of Chemical and Biomolecular Engineering won the Chem-E-Car Competition 2016, which took place on November 13 at the Union Square in San Francisco. The students who participated were Young-Hyun Cha, Jin-Sol Shin, Dae-Seok Oh, and Wan-Tae Kim. Their adviser was Professor Doh Chang Lee of the same department.
Established in 1999, the Chem-E-Car is an annual worldwide college competition for students majoring in chemical engineering. The American Institute of Chemical Engineers (AIChE), founded in 1908, is the world’s leading organization for chemical engineering professionals with more than 50,000 members from over 100 countries and hosts this competition every year.
A total of 41 university teams including Carnegie Mellon University and Purdue University participated in this year’s competition.
KAIST students competed in the event for the first time in 2014 and reached the rank of 28. In 2015, the students placed 16th, and finally, took the first place in last month’s competition, followed by the Georgia Institute of Technology.
In the competition, students must design small-scale (20x30x40 cm) automobiles that operate chemically, as well as describe their research and drive their car a fixed distance down a wedge-shaped course to demonstrate the car’s capabilities. In addition to driving a specified distance (15-30 meters), the car must hold a payload of 0-500 mL of water.
The organizers tell participants the exact distance and amount of payloads one hour before the competition begins. Winners are chosen based on their finishing time and how close their car reaches the finish line. Thus, students must show sophisticated coordination of chemical reactions to win.
The KAIST team designed their car to have a stable power output using a Vanadium redox flow battery developed by Professor Hee Tak Kim of Chemical and Biomolecular Engineering. They employed iodine clock reactions to induce quick and precise chemical reactions to control their car.
KAIST’s car finished with the best run coming within 11 cm of the target line; Georgia Tech’s car reached the finish line by 13 cm and New Jersey Institute of Technology’s car by 14 cm.
Young-Hyun Cha, one of the four students, said, “When we first designed our car, we had to deal with many issues such as stalls or connection errors. We kept working on fixing these problems through trial and error, which eventually led us to success.”
For a news article on KAIST’s win at 2016 Chemi-E-Car Competition by AIChE, see the link below:
http://www.aiche.org/chenected/2016/11/koreas-kaist-wins-1st-place-2016-chem-e-car-competition-photos
2016.12.08 View 9671 -
Mobile Software Platform Research Center Recognized by the MSIP
The Mobile Software Platform Research Center (MSPRC) at KAIST received an award from the Minister of Science, ICT and Future Planning of Korea on November 29, 2016, at Coex in Seoul. The award was presented at the Conference of Software R&D Annual Report 2016 hosted by the Ministry of Science, ICT and Future Planning (MISP) and the Institute for Information and Communications Technology Promotion (IITP).
The research center developed user experience (UX)-oriented mobile software platforms that support the invention of next-generation UX service technologies. The center has filed 37 patents and registered 15 technologies. Its researchers received ten Best Paper Awards and published a total of 133 papers in Korean and international journals.
Research teams at MSPRC expect that their software platforms will offer training programs for software engineers and new UX services. They also said that their extensive event processing platforms would reduce energy consumption on mobile devices.
Professor Seungryoul Maeng of the School of Computing, the Director of MSPRC, said, “This is a great honor for us. I am greatly thankful for the teamwork of participating departments--Computer Science, Industrial Design, and Industrial and Systems Engineering. We will continue to introduce our research outcomes and to work towards commercializing these results.”
Members of the Mobile Software Platform Research Center, KAIST
2016.12.07 View 6466