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Samsung Electronics' Chairman Kwon Becomes the First Alumnus Honorary Doctorate
(Samsung Electronics' Chairman & CEO Kwon,left, and President Shin)
The semiconductor has bred innovation in Korea, as one of the staples of economic growth. Without the success of the semiconductor industry of Korea, it is hard to imagine the high tech dominance in the global market enjoyed by Korean companies.
It is said that one in every four Ph.D.s working in the semiconductor industry of Korea graduated from KAIST. Among them, Chairman and CEO Oh-Hyun Kwon of Samsung Electronics, Class of 1977, has arrived at the epitome of this top industry.
KAIST’s class of 1977 produced many movers and shakers in Korea’s innovation efforts. Now in their mid-60s, they were the players who embodied Korea’s ICT and helped it become a global powerhouse. They are the ones who worked for and witnessed the socio-economic transformation of Korea through innovation.
In recognition of his unsurpassable entrepreneurship, which made the remarkable strides in the semiconductor and electronics industry in Korea and beyond, Chairman Kwon was honored as the first recipient of an honorary doctorate from his alma mater on February 23 during the 2018 commencement ceremony.
After completing his Master's in Electrical Engineering at KAIST in 1977, he earned his Ph.D. in Electrical Engineering from Stanford University. The first honorary degree bestowed to an alumnus was conferred by the first alumnus President of KAIST Sung-Chul Shin. President Shin said that Chairman Kwon’s exceptional leadership has inspired the KAIST community and exemplified the spirit of KAIST.
Currently serving as chairman & CEO of Samsung Electronics and Samsung Advanced Institute of Technology (SAIT), Kwon has worked for Samsung in a variety of key positions in their semiconductor division since 1985.
In the mid-1980s, Japan was leading the global semiconductor market. At Samsung, Chairman Kwon, who was in charge of the memory semiconductor team, successfully developed 4M DRAM. Later in 1992, he played a leading role in the development of the world’s first 64M DRAM.
The success of 4M DRAM and 64M DRAM led Samsung to clinch the top position in the DRAM and NAND flash business around the world. This helped Samsung emerge as a global leader in the semiconductor industry.
As a result, Samsung, as well as the national economy, could gain significant momentum to build national competitiveness and economic growth. The outstanding technological leadership of Chairman Kwon led to the development of proprietary semiconductor design and processes technologies as well as numerous patents.
He also played a leadership role in creating a mutual growth environment among conglomerates rather than merely engaging in direct competition. Chairman Kwon made every effort to establish the cornerstone of mutual growth, especially in relationships with small and medium-sized enterprises (SMEs). His win-win collaboration initiatives among conglomerates and SMEs made a significant impact on the development of the entire industry of Korea.
In his acceptance speech, he charged the graduates to embrace challenges, to collaborate with peers, and create their own future.
The full text of his speech is printed below.
Graduates and distinguished guests! I extend my sincere congratulations to my fellow graduates, as you are awarded degrees for your deep efforts, as well as to the parents and family members who have supported you.
In 1977, I received my Master’s degree in Electrical Engineering from KAIST. Today, as the first honorary doctor among KAIST graduates, I am truly honored to be here. I am deeply grateful to all of you, including President Sung-Chul Shin and the Chairman of the Board of Trustees, Jang-Moo Lee.
Today, I want to tell you about the experiences and lessons I have learned from my 40 years of corporate management experience.
First, you should lead and drive changes by yourself. In the process of realizing a dream, the situation and circumstances do not always proceed as you planned.
I started my career as a researcher. However, I had to continuously transform myself into a project leader, business team leader, and CEO. It was challenging every time, due to a lack of preparing and my insufficient ability. However, I have always accomplished the intended goal through the mindset of embracing changes and studying new things.
It is said that the survivors are not always the strongest nor the most intelligent, but the ones who are the most adaptive to changes. We can only be the last survivor if we have the character to see those small signs that signal changes are coming and cope with changes well. Take changes positively and actively and then, transform yourself to match a given situation.
In addition, it is important to understand others. When it comes to one’s career, there is nothing that you can do alone without the assistance of others. If it is not possible to do everything by yourself, you will need to supplement your efforts through the help of others. To do this, you need to understand your colleagues, bosses, and customers first.
People, who work in tech tend to cage themselves in their own silos. But in an era of destructive innovation, where boundaries of industries and technologies are collapsing at a breakneck pace, scientists also need to enhance their understanding of various areas such as culture, art, and the humanities.
This is a famous verse from a poem by Chun-Soo Kim.
Before I called his name,
He was nothing but a gesture.
When I called his name, He came to me and became a flower.
Make wonderful synergy by making your partner a flower and complementing each other. When you first notice the true value of another person and interact with them, the value of the individual will be doubled and will bring about a greater impact.
Finally, we all need to cooperate with each other. All of you here, including myself, are people who have benefited from society. We must cooperate with each other and give back to society for the best results.
A biologist once said that incremental evolution comes from competition, but fundamental evolution comes from cooperation. Great leaders should achieve results through cooperation rather than competition.
You are the future leaders with top-class knowledge. I hope you will become great leaders who have wisdom that combines external resources with your abilities.
Now, graduates of 2018 who are standing at the starting line, we often worry about an unpredictable tomorrow. However, the smartest way to predict the future is to create the future for ourselves. Moreover, we can try again even though we sometimes make mistakes. I urge you to make future you are hoping for.
Once again, I would like to thank you for this honorary doctorate and extend my sincere wishes for the endless development of KAIST and the best of luck to the futures of these graduates. Thank you.
2018.02.26 View 8113 -
The 2018 Commencement of KAIST at a Glance
KAIST awarded a total of 2, 736 degrees at the 2018 commencement ceremony on February 23. Among the honorees, Chairman and CEO of Samsung Electronics and Samsung Advanced Institute of Technology (SAIT) Oh-Hyun Kwon was recognized as the first alumnus honorary doctorate recipient of KAIST.
More than 5,000 family, friends, and graduates including distinguished guests of Minister of Science and ICT Young-Min Yu, the Member of National Assembly Kyung-Jin Kim, Chairman of the KAIST Board of Trustees Jang-Moo Lee, and the Chairperson of the KAIST Development Foundation Soo-Young Lee attended to celebrate the graduates. During the commencement, a total of 2,736 students earned degrees: 644 PhD degrees, 1,352 master’s degrees, and 740 bachelor’s degrees.
(Minister of Science and ICT Young-Min Yu)
(The Member of National Assembly Kyung-Jin Kim)
This year, Chairman and CEO of Samsung Electronics and SAIT Kwon shared the spotlight with many other graduates. Kwon received his Master’s degree in Electrical Engineering from KAIST in 1977 and completed his Ph.D. in Electrical Engineering from Stanford University in 1985. During his more than 33-year career at Samsung, he has made significant contribution to the development of 4M DRAM and the world’s first 64M DRAM. The success of 4M DRAM and 64 DRAM led Samsung to clinch the top position in the DRAM and NAND flash business around the world. This helped Samsung emerge as a global leader in the semiconductor industry.
(From left: Chairman and CEO of Samsung Electronics and SAIT Oh-Hyun Kwon and KAIST President Sung-Chul Shin)
During the commencement speech, Kwon and President Shin both highlighted the importance of collaboration instead of competition.
Kwon encouraged the graduates to understand others to make wonderful synergy. “When you first notice the true value of another person and interact with them, the value of the individual will be doubled and will bring about a greater impact,” he said.
Also, he stressed having a collaborative mindset by saying, “All of you here, including myself, are people who have benefited from society. We must cooperate with each other and give back to society for the vest results.”
While highlighting the core values of KAIST, creativity, challenge and caring, President Shin also emphasized collaboration with others. He said, “In the future, expertise in a single discipline will not lead to new inventions or discoveries. This highlights the importance of multidisciplinary, convergence research. The key to success lies in the acknowledgement of your peers as partners for mutual growth. Your partners will make up your weak areas and become your most important asset. May you expand your personal network by finding valuable partners not only within your laboratory and workplace, but beyond Korea.”
“Go out into the world and change it as a global shaper, global innovator, and global mover. I hope that each and every one of you will add benefits the world and your legacy will be remembered for generations to come. This is your obligation as a graduate of KAIST,” he said.
Click here to view the full text of President Sung-Chul Shin’s address to the graduates
+ List of academically outstanding undergraduate degree recipients who received honors during the Commencement 2018 of KAIST
Award
Department
Winner
Minister of Science and ICT Award
Dept. of Mathematical Sciences
Seong-Hyeok Park
KAIST Board Chairperson Award
School of Computing
Hyeong-Seok Kim
KAIST President Award
Dept. of Chemistry
Hoi-Min Cheong
KAIST Development Foundation Chairperson Award
Dept. of Biological Sciences
Gi-Song Kim
Dept. of Industrial & Systems Engineering
Seung-Hun Lee
2018.02.23 View 11515 -
Soul-Searching & Odds-Defying Determination: A Commencement Story of Dr. Tae-Hyun Oh
(Dr. Tae-Hyun Oh, one of the 2736 graduates of the 2018)
Each and every one of the 2,736 graduates has come a long way to the 2018 Commencement. Tae-Hyun Oh, who just started his new research career at MIT after completing his Ph.D. at KAIST, is no exception.
Unlike the most KAIST freshmen straight out of the ingenious science academies of Korea, he is among the many who endured very challenging and turbulent adolescent years. Buffeted by family instability and struggling during his time at school, he saw himself trapped by seemingly impenetrable barriers. His mother, who hated to see his struggling, advised him to take a break to reflect on who he is and what he wanted to do.
After dropping out of high school in his first year, ways to make money and support his family occupied his thoughts. He took on odd jobs from a car body shop to a gas station, but the real world was very tough and sometimes even cruel to the high school dropout.
Bias and prejudice stigmatizing dropouts hurt him so much. He often overheard a parent who dropped by the body shop that he worked in saying, “If you do not study hard, you will end up like this guy.” Hearing such things terrified him and awoke his sense of purpose. So he decided to do something meaningful and be a better man than he was.
“I didn’t like the person I was growing up to become. I needed to find myself and get away from the place I was growing up. It was my adventure and it was the best decision I ever made,” says Oh.
After completing his high school diploma national certificate, he planned to apply to an engineering college. On his second try, he gained admission into the Department of Electrical Engineering at Kwang Woon University with a full scholarship. He was so thrilled for this opportunity and hoped he could do well at college. Signal processing and image processing became the interest of his research and he finished his undergraduate degree summa cum laude.
Gaining confidence in his studies, he searched around graduate school department websites in Korea to select the path he was interested in. Among others, the Robotics and Computer Vision Lab of Professor In-So Kweon at the Department of Electrical Engineering at KAIST was attractive to him.
Professor Kweon’s lab is globally renowned for robot vision technology. Their technologies were applied into HUBO, the KAIST-developed bimodal humanoid robot that won the 2015 DARPA Challenges.
“I am so appreciate of Professor Kweon, who accepted and guided me,” he said. Under Professor Kweon’s advising, he could finish his Master’s and Ph.D. courses in seven years. The mathematical modeling on fundamental computer algorithms became his main research topic.
While at KAIST, his academic research has blossomed. He won a total of 13 research prizes sponsored by corporations at home and abroad such as Kolon, Samsung, Hyundai Motors, and Qualcomm.
In 2015, he won the Microsoft Research Asia Fellowship as the sole Korean among 13 Ph.D. candidates in the Asian region. With the MSRA fellowship, he could intern at the MS Research Beijing Office for half a year and then in Redmond, Washington in the US.
“Professor Kweon’s lab filled me up with knowledge. Whenever I presented our team’s paper at an international conference, I was amazed by the strong interest shown by foreign experts, researchers, and professors. Their strong support and interest encouraged me a lot. I was fully charged with the belief that I could go abroad and explore more opportunities,” he said.
Dr. Oh, who completed his dissertation last fall, now works at the Department of Electrical Engineering and Computer Science at MIT under Professor Wojciech Matusik.
“I think the research environment at KAIST is on par with MIT. I have very rich resources for my studies and research at both schools, but at MIT the working culture is a little different and it remains a big challenge for me. I am still not familiar with collaborative work with colleagues from very diverse backgrounds and countries, and to persuade them and communicate with them is very tough. But I think I am getting better and better,” he said.
Oh, who is an avid computer game player as well, said life seems to be a game. The level of the game will be upgraded to the next level after something is accomplished. He feels great joy when he is moving up and he believes such diverse experiences have helped him become a better person day by day. Once he identified what gave him a strong sense of purpose, he wasn’t stressed out by his studies any more. He was so excited to be able to follow his passion and is ready for the next challenge.
2018.02.23 View 10787 -
KAIST, First to Win the Cube Satellite Competition
Professor Hyochoong Bang from the Department of Aerospace Engineering and his team received the Minister of Science and ICT Award at the 1st Cube Satellite Competition.
The team actually participated in the competition in 2012, but it took several years for the awarding ceremony since it took years for the satellites to be designed, produced, and launched.
The KAIST team successfully developed a cube satellite, named ‘Little Intelligent Nanosatellite of KAIST (LINK)’ and completed its launch in April 2017.
LINK (size: 20cmx10cmx10cm, weight: 2kg) mounted mass spectrometry and Langmuir probe for Earth observation. The Langmuir probe was developed by Professor Kyoung Wook Min from the Department of Physics, KAIST.
Yeerang Lim, a PhD student from the Department of Aerospace Engineering said, “I still remember the feeling that I had on the day when LINK launched into orbit and sent back signals. I hope that space exploration is not something far away but attainable for us in near future.”
2018.02.22 View 11223 -
First Female Grand Prize Awardee of Samsung Humantech
Yeunhee Huh, PhD candidate (Professor Gyu-Hyeong Cho) from the School of Electrical Engineering received the grand prize of the 24th Humantech Paper Award. She is the first female recipient of this prize since its establishment in 1994. The Humantech Paper Award is hosted by Samsung Electronics and sponsored by the Ministry of Science and ICT with JoongAng Daily Newspaper. Her paper is titled, ‘A Hybrid Structure Dual-Path Step-Down Converter with 96.2％ Peak Efficiency using 250mΩ Large-DCR Inductor’. Electronic devices require numerous chips and have a power converter to supply energy adequately. She proposed a new structure to enhance energy efficiency by combining inductors and capacitors. Enhancing energy efficiency can reduce energy loss, which prolongs battery hours and solves overheating of devices; for instance, energy loss leads to the overheating issue affecting phone chargers. This technology can be applied to various electronic devices, such as cell phones, laptops, and drones. Huh said, “Power has to go up in order to meet customers’ needs; however the overheating problem emerges during this process. This problem affects surrounding circuits and causes other issues, such as malfunctions of electronic devices. This technology may vary according to the conditions, but it can enhance energy efficiency up to 4%.”During the ceremony, about eight hundred million KRW worth cash prizes was conferred to 119 papers. KAIST (44 papers) and Gyeonggi Science High School (6 papers) received special awards given to the schools.
2018.02.12 View 9265 -
Professor Hojong Chang Wins the Best Paper Award at ISIITA 2018
Professor Hojong Chang from the KAIST Institute won the best paper award at the International Symposium on Innovation in Information Technology and Application (ISIITA) 2018.
ISIITA is a global networking symposium in which leading researchers in the field of information technology and applications gather to exchange knowledge on technological convergence.
Professor Chang won the prize for his paper, titled ‘A Study on the Measurement of Aptamer in Urine Using SiPM’.
This paper proposes using aptamer to measure and analyze the density of sodium and potassium contained in urine, allowing diseases to be diagnosed in advance.
Professor Chang said, “With a point-of-care test system that facilitates a quick diagnosis without extra processes, such as centrifugation, it is possible to get an early diagnosis and check infection in real time. Through generalizing this crucial technology, we expect to develop adequate technology for enhancing quality of life.
2018.02.12 View 8142 -
Professor Jungwon Kim Wins Haerim Optics and Photonics Award
(Professor Jungwon Kim)
Professor Jungwon Kim from the Department of Mechanical Engineering received the 8th Haerim Optics and Photonics Award from the Optical Society of Korea (OSK).
He was recognized for his dedication to pioneering the field of microwave photonics by developing ultra-low noise fiber photonics lasers.
The Haerim Optics and Photonics Award is given to an outstanding researcher who has made academic contributions in the field of optics and photonics for the last five years.
The name of the award (Haerim) comes from the pen-name of the renowned scholar, Professor Un-Chul Paek, because it is maintained using funds he contributed to the OSK.
The OSK will confer the award on February 8 during the 29th OSK Annual Meeting and Winter Conference of 2018.
2018.02.07 View 7586 -
KAIST to Host the THE Innovation & Impact Summit in 2019
KAIST and Times Higher Education (THE) agreed to co-host the THE Innovation & Impact Summit at KAIST from April 1 to 3, 2019.
Global leaders from higher education, government, and industry will gather at KAIST to discuss how universities can better innovate for creating a greater impact.
(from left: THE Managing Director Trevor Barratt and KAIST President Sung-Chul Shin)
President Sung-Chul Shin and Trevor Barratt, managing director at the THE, signed an agreement to host the 2019 THE Innovation & Impact Summit at KAIST next April. The agreement was signed on February 6 during the THE Asia Universities Summit held at SUSTech in Shenzhen in China. Phil Baty, editorial director at the THE was also present during the agreement.
By hosting the 2019 THE Innovation & Impact Summit, KAIST has a chance to introduce its innovative research and performance and its educational environment and startup ecosystem to the world. Having educational and industrial leaders meet at KAIST will add more power to the global status and capacity of KAIST.
The THE Innovation & Impact Summit, first held in 2017, is one in the seven presidential summit series held by THE. During the second summit at KAIST, THE will launch their world university innovation rankings for the first time.
As innovation at universities and its impact have been a crucial indicator in building an institutional brand and reputation, leading universities are gearing up to encourage startups and entrepreneurship education. Even more, innovation at universities is emerging as one of the growth engines of economies.
The innovation indicators of KAIST have been highly recognized by many global ranking institutions in terms of the volume of patents and the patents-to-article citation impact. Thomson Reuters has recognized KAIST for two consecutive years as the most innovative university in Asia, and sixth in the world.
President Shin has high expectations for the hosting of the Innovation & Impact Summit at KAIST. He explained, “Innovation makes up the DNA of KAIST and it has been our institutional mission from the start in 1971. KAIST was commissioned to make innovation for industrialization and economic development through education and research. I do not see any university more suitable than KAIST to host this innovation summit. I hope the summit at KAIST will serve as a global platform to provide very creative ideas for making innovation and collaboration among the leading universities for all the participants.”
Meanwhile, at the THE Asia Universities Summit in Shenzhen, how to respond to the implications of the Fourth Industrial Revolution was the key agenda piercing the two-day sessions.
As a panelist, President Shin shared his experiences on innovative strategies viable for spearheading university reform for the Fourth Industrial Revolution, along with Vice-Chancellor of the University of Sheffield Sir Keith Burnett, President of Monash University Margaret Gardner, and President of Hong Kong Polytechnic University President Timothy W. Tong. He said that universities should foster young talents by equipping them with creativity, collaboration, and convergent minds. To swiftly respond to the new industrial environment, President Shin said that universities should remove the high barriers between departments and establish cross- and inter-disciplinary education systems, convergence research and technology commercialization.
2018.02.06 View 9086 -
Structural Insight into the Molecular Mechanism of PET Degradation
A KAIST metabolic engineering research team has newly suggested a molecular mechanism showing superior degradability of poly ethylene terephthalate (PET).
This is the first report to simultaneously determine the 3D crystal structure of Ideonella sakaiensis PETase and develop the new variant with enhanced PET degradation.
Recently, diverse research projects are working to address the non-degradability of materials. A poly ethylene terephthalate (PET)-degrading bacterium called Ideonella sakaiensis was recently identified for the possible degradation and recycling of PET by Japanese team in Science journal (Yoshida et al., 2016). However, the detailed molecular mechanism of PET degradation has not been yet identified.
The team under Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering and the team under Professor Kyung-Jin Kim of the Department of Biotechnology at Kyungpook National University conducted this research. The findings were published in Nature Communications on January 26.
This research predicts a special molecular mechanism based on the docking simulation between PETase and a PET alternative mimic substrate. Furthermore, they succeeded in constructing the variant for IsPETase with enhanced PET-degrading activity using structural-based protein engineering.
It is expected that the new approaches taken in this research can be background for further study of other enzymes capable of degrading not only PET but other plastics as well.
PET is very important source in our daily lives. However, PET after use causes tremendous contamination issues to our environment due to its non-biodegradability, which has been a major advantage of PET. Conventionally, PET is disposed of in landfills, using incineration, and sometimes recycling using chemical methods, which induces additional environmental pollution. Therefore, a new development for highly-efficient PET degrading enzymes is essential to degrade PET using bio-based eco-friendly methods.
Recently, a new bacterial species, Ideonella sakaiensis, which can use PET as a carbon source, was isolated. The PETase of I. sakaiensis (IsPETase) can degrade PET with relatively higher success than other PET-degrading enzymes. However, the detailed enzyme mechanism has not been elucidated, hindering further studies.
The research teams investigated how the substrate binds to the enzyme and which differences in enzyme structure result in significantly higher PET degrading activity compared with other cutinases and esterases, which make IsPETase highly attractive for industrial applications toward PET waste recycling.
Based on the 3D structure and related biochemical studies, they successfully predicted the reasons for extraordinary PET degrading activity of IsPETase and suggested other enzymes that can degrade PET with a newly-classified phylogenetic tree. The team proposed that 4 MHET moieties are the most properly matched substrates due to a cleft on structure even with the 10-20-mers for PET. This is meaningful in that it is the first docking simulation between PETase and PET, not its monomer.
Furthermore, they succeeded in developing a new variant with much higher PET-degrading activity using a crystal structure of this variant to show that the changed structure is better to accommodate PET substrates than wild type PETase, which will lead to developing further superior enzymes and constructing platforms for microbial plastic recycling.
Professor Lee said, “Environmental pollution from plastics remains one of the greatest challenges worldwide with the increasing consumption of plastics. We successfully constructed a new superior PET-degrading variant with the determination of a crystal structure of PETase and its degrading molecular mechanism. This novel technology will help further studies to engineer more superior enzymes with high efficiency in degrading. This will be the subject of our team’s ongoing research projects to address the global environmental pollution problem for next generation.”
This work was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries (NRF-2012M1A2A2026556 and NRF-2012M1A2A2026557) from the Ministry of Science and ICT through the National Research Foundation of Korea. Further Contact: Dr. Sang Yup Lee, Distinguished Professor, KAIST, Daejeon, Korea (leesy@kaist.ac.kr, +82-42-350-3930)
(Figure: Structural insight into the molecular mechanism of poly(ethylene terephthalate) degradation and the phylogenetic tree of possible PET degrading enzymes. This schematic diagram shows the overall conceptualization for structural insight into the molecular mechanism of poly (ethylene terephthalate) degradation and the phylogenetic tree of possible PET degrading enzymes.)
2018.01.31 View 9310 -
Developing Flexible Vertical Micro LED
A KAIST research team led by Professor Keon Jae Lee from the Department of Materials Science and Engineering and Professor Daesoo Kim from the Department of Biological Sciences has developed flexible vertical micro LEDs (f-VLEDs) using anisotropic conductive film (ACF)-based transfer and interconnection technology. The team also succeeded in controlling animal behavior via optogenetic stimulation of the f-VLEDs.
Flexible micro LEDs have become a strong candidate for the next-generation display due to their ultra-low power consumption, fast response speed, and excellent flexibility. However, the previous micro LED technology had critical issues such as poor device efficiency, low thermal reliability, and the lack of interconnection technology for high-resolution micro LED displays.
The research team has designed new transfer equipment and fabricated a f-VLED array (50ⅹ50) using simultaneous transfer and interconnection through the precise alignment of ACF bonding process. These f-VLEDs (thickness: 5 ㎛, size: below 80 ㎛) achieved optical power density (30 mW/mm2) three times higher than that of lateral micro LEDs, improving thermal reliability and lifetime by reducing heat generation within the thin film LEDs.
These f-VLEDs can be applied to optogenetics for controlling the behavior of neuron cells and brains. In contrast to the electrical stimulation that activates all of the neurons in brain, optogenetics can stimulate specific excitatory or inhibitory neurons within the localized cortical areas of the brain, which facilitates precise analysis, high-resolution mapping, and neuron modulation of animal brains. (Refer to the author’s previous ACS Nano paper of “Optogenetic Mapping of Functional Connectivity in Freely Moving Mice via Insertable Wrapping Electrode Array Beneath the Skull.” )
In this work, they inserted the innovative f-VLEDs into the narrow space between the skull and the brain surface and succeeded in controlling mouse behavior by illuminating motor neurons on two-dimensional cortical areas located deep below the brain surface.
Professor Lee said, “The flexible vertical micro LED can be used in low-power smart watches, mobile displays, and wearable lighting. In addition, these flexible optoelectronic devices are suitable for biomedical applications such as brain science, phototherapeutic treatment, and contact lens biosensors.”
He recently established a startup company ( FRONICS Inc. ) based on micro LED technology and is looking for global partnerships for commercialization. This result entitled “ Optogenetic Control of Body Movements via Flexible Vertical Light-Emitting Diodes on Brain Surface ” was published in the February 2018 issue of Nano Energy.
Figure 1. Comparison of μ-LEDs Technology
2018.01.29 View 13257 -
Cellular Mechanism for Severe Viral Hepatitis Identified
(Professor Shin(left) and Professor Jung)
KAIST medical scientists identified a cellular mechanism causing inflammatory changes in regulatory T cells that can lead to severe viral hepatitis. Research on this mechanism will help further understand the nature of various inflammatory diseases and lead to the development of relevant clinical treatments.
It is known that activated immune cells of patients with viral hepatitis destroy hepatocyte, but its regulatory mechanism has not yet been described.
Regulatory T cells inhibit activation of other immune cells and thus are important for homeostasis of the immune system. However, recent studies contradictorily show that immune inhibitory functions of regulatory T cells weaken in inflammatory conditions and the cells secrete inflammatory cytokines in response. Meanwhile, such a phenomenon was not observed in viral hepatitis including types A, B and C.
The team focused on changes in regulatory T cells in patients with viral hepatitis and discovered that regulatory T cells undergo inflammatory changes to secrete inflammatory cytokines (protein secreted by immune cells) called TNF. They also proved regulatory T cells that secrete TNF contribute to the progression of viral hepatitis.
The team confirmed that regulatory T cells of acute hepatitis A patients have reduced immune-inhibitory functions. Instead, their regulatory T cells secrete TNF. Through this research, the team identified a molecular mechanism for changes in regulatory T cells and identified the transcription factor regulating the process. Furthermore, the team found similar changes to be also present in hepatitis B and C patients.
A KAIST immunology research team led by Professors Eui-Cheol Shin and Min Kyung Jung at the Graduate School of Medical Science & Engineering conducted this translational research with teams from Chungnam National University and Yonsei University to identify the mechanism in humans, instead of using animal models. The research was described in Gastroenterology last December.
Professor Shin said, “This is the first research on regulatory T cells that contributes to hepatocyte damage in viral hepatitis.” He continued, “It is significant for identifying the cells and the molecules that can be used as effective treatment targets for viral hepatitis in the future. This research was funded by the Samsung Science and Technology Foundation.
(Figure1: Treg cells from acute hepatitis A (AHA) patients produce tumor necrosis factor (TNF) andhave reduced suppressive activity. These changes are due to a decrease in FoxP3 transcription factor and an increase in RORγt transcription factor. TNF-producing Treg cells are associated with severe liver injury in AHA patients.)
(Figure 2: A higher proportion of Treg cells from patients with acute hepatitis A, compared with healthy controls, produced TNF upon stimulation with anti-CD3 and anti-CD2. This study reports the presence and the significance of TNF-producing Treg cells for the first time in human patients.)
2018.01.18 View 8577 -
Three Professors Named KAST Fellows
(Professor Dan Keun Sung at the center)
(Professor Y.H. Cho at the center)
(Professor K.H. Cho at the center)
The Korean Academy of Science and Technology (KAST) inducted three KAIST professors as fellows at the New Year’s ceremony held at KAST on January 12. They were among the 24 newly elected fellows of the most distinguished academy in Korea. The new fellows are Professor Dan Keun Sung of the School of Electrical Engineering, Professor Kwang-Hyun Cho of the Department of Bio and Brain Engineering, and Professor Yong-Hoon Cho of the Department of Physics.
Professor Sung was recognized for his lifetime academic achievements in fields related with network protocols and energy ICT. He also played a crucial role in launching the Korean satellites KITSAT-1,2,3 and the establishment of the Satellite Technology Research Center at KAIST.
Professor Y.H.Cho has been a pioneer in the field of low-dimensional semiconductor-powered quantum photonics that enables quantum optical research in solid state. He has been recognized as a renowned scholar in this field internationally.
Professor K.H.Cho has conducted original research that combines IT and BT in systems biology and has applied novel technologies of electronic modeling and computer simulation analysis for investigating complex life sciences. Professor Cho, who is in his 40s, is the youngest fellow among the newly inducted fellows.
2018.01.16 View 14104