본문 바로가기
대메뉴 바로가기
KAIST
Newsletter Vol.25
Receive KAIST news by email!
View
Subscribe
Close
Type your e-mail address here.
Subscribe
Close
KAIST
NEWS
유틸열기
홈페이지 통합검색
-
검색
KOREAN
메뉴 열기
Science
by recently order
by view order
New Technology Developed for Analysis of New Drugs by Using Smart Nano-Sensors
Doctor Sang-Kyu Lee Doctor Sang-Kyu Lee of the Department of Biological Sciences, KAIST, has developed the technology that allows biological nano particles to be implanted into human cells for monitoring the effect of new drugs in real time from within the cell. It is expected that this technology will boost the ability to weigh the effects and properties of a new drug more quickly and accurately. Conventionally, the candidate drug was injected into the human body, and then its cells are extracted to analyze the effects of the drugs. The problem with this method was that the cells were analyzed at a ‘dead’ state which made it incredibly difficult to find candidate substances due to uncontrollable side effects. This made the development of new drugs very difficult despite the large costs and efforts invested into its development. The research team latched onto the idea that nanoparticles can connect to form a large complex. The complex acts as a nanosensor which allows for real time observation of drug target and the drug itself binding. The team named the nanosensor technology ‘InCell SMART-i’ and was named ‘Hot Paper’ of the September edition of ‘Angewandte Chemie International Edition’ magazine, a world famous Chemistry Magazine.When a new drug injected into the human body, the drug and drug targets are gradually combined, and the smart nanosensor detects in real time the effect of the new drug as shown in the pictures above (shaded spot).
2011.09.19
View 9042
Scientists develop highly efficient industrial catalyst
http://english.yonhapnews.co.kr/business/2011/07/14/48/0501000000AEN20110714009600320F.HTML SEOUL, July 15 (Yonhap) -- South Korean scientists said Friday that they have developed a highly efficient nanoporous industrial catalyst that can have a considerable impact on chemical and oil-refining sectors. The team of scientists led by Ryoo Ryong, a chemistry professor at the Korea Advanced Institute of Science and Technology (KAIST), said the solid zeolite compound developed in the laboratory has a reaction speed five to 10 times faster than that of conventional materials. Zeolite, which is made from silica and aluminium, is frequently used as an absorbent, water purifier and in nuclear reprocessing, although it is mainly employed in the chemical industry. The annual size of the zeolite market is estimated at US$2.5 billion with output using the material topping $30 billion. At present, 41 percent of all catalysts used in the chemical sector are nano-scale zeolite materials. The KAIST team said that because the new zeolite is made up of different sized pores, the material can be used as a catalyst when existing materials are unable to act as a changing agent. "Existing zeolites only have pores under 1 nanometer in diameter, but the new material has holes that range from 1 nanometer to 3.5 nanometers, which are all arranged in a regular honeycomb arrangement," Ryoo said. A nanometer is one-billionth of a meter. He said the ability to have both micro- and meso-sized pores is key to the faster reaction speed that is an integral part of raising efficiency. The South Korean researchers used a so-called surfactant process to make the different sizes of pores. The development is a breakthrough because researchers and companies such as Exxon Mobil Corp. have been trying to build zeolite with different sizes of pores for the past two decades without making serious headway. There are more than 200 different types of zeolites in the world. Ryoo, who received funding from the government, has requested intellectual property rights for the discovery, which has been published in the latest issue of Science magazine. He also developed another zeolite in the past that can transform methanol to gasoline up to 10 times more efficiently than existing catalysts. Exxon Mobil has expressed interest in the two zeolites made by Ryoo"s team. Undisclosed South Korean petrochemical companies have also made inquiries that may lead to commercial development in the future. "There are some technical issues to resolve, mainly related with mass production and stability," the scientist said. He said full-fledge production will be determined by how much companies are willing to spend on research to speed up development that can bring down overall production costs. The KAIST team said it took two years to make the new zeolite, which can be custom made to meet specific needs. (END)
2011.07.15
View 11363
Biomimetic Carbon Nanotube Fiber Synthesis Technology Developed
The byssus of the mussel allows it to live in harsh conditions where it is constantly battered by crashing waves by allowing the mussel to latch onto the seaside rocks. This particular characteristic of the mussel is due to the unique structure and high adhesiveness of the mussel’s byssus. KAIST’s Professor Hong Soon Hyung (Department of Material Science and Engineering) and Professor Lee Hae Shin (Department of Chemistry) and the late Professor Park Tae Kwan (Department of Bio Engineering) were able to reproduce the mussel’s byssus using carbon nanotubes. The carbon nanotube, since its discovery in 1991, was regarded as the next generation material due to its electrical, thermal, and mechanical properties. However due to its short length of several nanometers, its industrial use was limited. The KAIST research team referred to the structure of the byssus of the mussel to solve this problem. The byssus is composed of collagen fibers and Mefp-1 protein which are in a cross-linking structure. The Mefp-1 protein has catecholamine that allows it to bind strongly with the collagen fiber. In the artificial structure, the carbon nanotube took on the role of the collagen fibers and the macromolecular adhesive took on the role of the catecholamine. The result was a fiber that was ultra-light and ultra-strong. The results of the experiment were published in the Advanced Materials magazine and is patent registered both domestically and internationally.
2011.06.20
View 11823
Research Conducted on the Development Policy of Medical Researchers in United States
The topic dealt in the paper was “The Vietnam War and Medical Research: Untold Legacy of the U.S. Doctor Draft and the NIH ‘Yellow Berets’” and basically deals how a Doctor Draft made a positive impact on improving the basic research of clinical medicine. Professor Park received his Doctorate at Johns Hopkins University and came to KAIST in 2007. Summary of Dissertation From the start of the Korean War in 1950 to the end of the Vietnam War in 1973 a large number of medical school graduates were drafted to the army. Of those drafted, 100 personnel were chosen annually to focus on researching in the National Institute of Health who developed into leaders of the field. For example, those who worked as a researcher at the National Institute instead of their armed services were 1.5 times more likely to become a tenured professor, 2 times more likely to be promoted to Dean of the department, and 3 times more likely to be the Dean. In addition, 9 out of 50 Nobel Prize winners in fields of natural sciences between 1985 and 2007 were from the same pool of researchers, and 10 out of 76 recipients of National Medal of Science were also from the same pool of researchers. They were named the ‘Yellow Berets’ like the special forces ‘Green Berets’ and made great contribution to the field in implementing and executing the bench to beside culture that involves development in laboratories to clinical testing. Professor Park maintains that there has to be improvements made in current policies to encourage research work in medical graduate schools.
2011.05.31
View 10429
From Pencil Lead to Batteries: the Unlimited Transformation of Carbon
Those materials, like lead or diamond, made completely up of Carbon are being used in numerous ways as materials or parts. Especially with the discovery of carbon nanotubes, graphemes, and other carbon based materials in nanoscale, the carbon based materials are receiving a lot of interest in both fields of research and industry. The carbon nanotubes and graphemes are considered as the ‘dream material’ and have a structure of a cross section of a bee hive. Such structure allows the material to have strength higher than that of a diamond and still be able to bend, be transparent and also conduct electricity. However the problem up till now was that these carbon structures appeared in layers and in bunches and were therefore hard to separate to individual layers or tubes. Professor Kim Sang Wook’s research team developed the technology that can assemble the grapheme and carbon nanotubes in a three dimensional manner. The team was able to assemble the grapheme ad carbon nanotubes in an entirely new three dimensional structure. In addition, the team was able to efficiently extract single layered grapheme from cheap pencil lead. Professor Kim is scheduled to give a guest lecture in the “Materials Research Society” in San Francisco and the paper was published in ‘Advanced Functional Materials’ magazine as an ‘Invited Feature Article’.
2011.05.11
View 10190
Dong Ah Newspaper Publish '100 Koreans who will Represent Korea in 10 years'
The 2011 list of ‘100 Koreans who will Represent Korea in 10 years’ published by Dong Ah Newspaper includes people of varying ages, vocation, and gender. In terms of University Professors, five professors from each of KAIST and SNU (Seoul National University) were selected. Especially Professor Charles Ahn received the most votes due to his world class talent, potential, and dedication. Professor Kim Sang Wook of the Department of Materials Science and Engineering is the world leading expert in the field of ‘Atom Construction Nanotechnology’ which deals with using macromolecules, carbon nanotubes, and grapheme to form various structures. His work on ‘low cost, large area nano patterning technology’ is expected to overcome the limits of nano treatment processes and its application in semi-conductors or displays carries great promise. Professor Kim Eun Sung of the Department of Physics discovered a new quantum behavior, supersolidity, in a low temperature, solid Helium for the first time in the world and is the leading scientist that leads the mechanics behind such a phenomenon. Professor Kim is leading the field of supersolidity through his works on hidden phase in a low temperature solid Helium, the understanding the role of crystalline faults in the supersolidity phenomenon, and the destruction of the supersolid’s macromolecular phenomenon through spinning solids. Professor Charles Ahn of the Graduate School of Innovation and Technology Management has been working as the developer of the V3 series (an anti-computer virus Vaccine Program) since 1988. He established the ‘Charles Ahn Research Center’ in 1995 and his solid and practical management style won him rave reviews. Professor Ahn was appointed as the Professor of the Graduate School of Innovation and Technology Management and has been teaching entrepreneurial perspective and Technology Management. Professor Lee Sang Yeop of the Department of Biology and Chemical Engineering developed world’s most efficient production method of succinic acid, developed high efficiency, tailored, culture for the production of key amino acids, Valine and Threonine, developed the production culture off bio-buthanol which is superior to bio-ethanol, and is widely known as one of the leaders in the field of metabolic engineering. Professor Jeong Ha Woong of the Department of Physics is being regarded as world leader in the field of Complex System Network Sciences. He implemented Statistical Physics to Complex Systems and also used the concept of ‘Networks’ and published 80 papers, including 5 which were published in Nature Magazine.
2011.04.30
View 12542
Genetic Cause of ADHD (Attention Deficit Hyperactivity Disorder) Found
The cooperative research team consisting research teams under Professor Kim Eun Joon and Professor Kang Chang Won of the department of Biological Sciences discovered that ADHD arises from the deficiency of GIT1 protein in the brain’s neural synapses. ADHD (Attention Deficit Hyperactivity Disorder) is found in around 5% of children around the world and is a disorder where the child becomes unable to concentrate, show over the top responses, and display impulsive behavior. The research team found that the difference between children with ADHD and those without it is one base in the GIT1 gene. The difference of a single base causes the underproduction of this protein, and those children with low levels of the protein had a higher probability to develop ADHD. In addition, further evidence was provided when the research team conducted mice experiments. Those mice with low levels of GIT1 exhibited impulsive and exaggerated reactions like humans with ADHD, had learning disabilities, and produced abnormal brain waves. And upon injecting these mice with cure for ADHD, the symptoms of ADHD disappeared. The impulsive behavior of ADHD children disappears as the child enters adulthood and a similar pattern was found in mice. A mice with low levels of GIT1 showed impulsive behaviors when 2 months old, but these behaviors disappeared as it got older to around 7 months old (equivalent to 20~30 years old for humans). Professor Kim Eun Joon commented that there has to be equilibrium between mechanisms that excite the neurons and mechanisms that calm the neurons, but the lack of GIT1 leads to the decrease in the mechanisms that calm the neurons which causes the impulsive behavior of ADHD patients. In addition, Professor Kang Chang Won commented that the results of the experiment has been receiving rave reviews and is being seen as the new method in the production of the cure for ADHD. The result of the experiment was published in the online edition of Nature Medicine magazine.
2011.04.30
View 10013
Businessweek: How Twitter Could Unleash World Peace, April 11, 2011
A KAIST graduate scholar, Meeyoung Cha, conducted a joint study with international researchers and released a paper on the aspect of twitter as an emerging cyber arena for political and social debates and discussions. An article on the paper from Businessweek follows: Businessweek April 11, 2011, 9:08PM EST text size: TT How Twitter Could Unleash World Peace Researchers from Britain, Korea, and Germany have determined that the amount of fresh information you get on Twitter is less a matter of what you follow than whom—and who follows you By Bobbie Johnson On certain days, Twitter can feel like the world"s biggest, fastest echo chamber. Since we tend to follow people who are similar to us, we often see our own views reflected back—meaning a gloomy cloud of irritation can rapidly swirl into a cyclone of outrage as we hear from other people who feel as we do. A group of computer scientists have discovered that the opposite may also be true. Can Twitter be part of the solution, not merely part of the problem? In a study to be presented at a conference in July, a team of researchers from the U.K."s University of Cambridge, Korea"s Graduate School of cultural Technology-KAIST, and Germany"s Max Planck Institute for Software Systems show how Twitter can provide users greater access to more varied political viewpoints and media sources than they might otherwise get. The paper, called "The Media Landscape in Twitter(http://www.cl.cam.ac.uk/~jac22/out/twitter-diverse.pdf)," explains how the team made surprising discoveries when they looked into the site"s usage patterns. First they looked at who follows whom and discovered that Twitter is a highly politicized space. Then they examined patterns of tweeting and retweeting to try to understand how people receive information on Twitter—and what they might see. Their conclusion: Although Twitter is a pretty partisan space, it can offer unprecedented opportunities to break down the barriers that plague local, national, and international politics. How? Through retweets and interaction—what the authors call "indirect media exposure." As they put it, this "expands the political diversity of news to which users are exposed to a surprising extent, increasing the range by between 60 percent and 98 percent. These results are valuable because they have not been readily available to traditional media and they can help predict how we will read news and how publishers will interact with us in the future." If you"re interested in the way Twitter works, I recommend reading the paper, which isn"t very long. Meanwhile, let"s boil it down to a few key pieces of data and see what lessons they can teach. Most Twitter users are political. Just over half (50.8 percent) of all Twitter users studied showed a distinct political bias in the media outlets and individuals they followed. Most of those lean to the left of the political spectrum, accounting for 62 percent of users who demonstrated some bias. Thirty-seven percent were doggedly centrist. Just 1 percent of Twitter users who showed a political preference were right-wing. Here are a couple of caveats about reading too much into the sharp divide the authors found. Given that Twitter"s user base is younger and more metropolitan than the societal norm, it"s not surprising that it"s weighted to the left. It"s worth noting that this study was undertaken more than a year ago; since then, Twitter has grown dramatically, while global politics have largely skewed back toward the right. Twitter"s user base today might reflect a more-balanced political picture. Either way, there"s a big split. Twitter has secondary and tertiary benefits. Most organizations comprehend Twitter in simple terms: More followers means more exposure. But the study shows that it"s not just about those you follow, but those your followers follow—essentially the people in your extended network. The network offers a number of routes for information from fresh sources to get to you. According to the study, some 80 percent of users choose to follow at least 10 media sources, but they are exposed to between 6 and 10 times as many media sources through their friends. People outweigh brands. Many of the biggest Twitter accounts are big media brands such as CNN (TWX) and Time, but the study suggests that Twitter"s active users tend to prefer individuals over outlets. So while the average follower of @NYTimes (NYT) has six followers apiece, individual journalists have followers who boast a median following count of around 100. That gives individual journalists—who are, the study says, more likely to link to a multiplicity of sources—a much wider, more influential network of connections. The inference is that the personal touch of a journalist is more important than the lofty, impersonal tone of publications that largely act as promotion channels for their content. It"s a discovery that reminded me of Twitter"s recent blog post on the science of the hashtag, which found that hashtags explode in usage when they are picked up by individuals with the most dedicated—not necessarily the largest—followings. Active users access a wider range of views. The researchers say that indirect exposure expands political diversity by a "significant amount," despite other studies showing a tendency for social networks to do the opposite. "Other studies have found a stronger tendency of homophily; blogs of different political views rarely linked to each other," they point out. "One possible reason is that a Twitter network encompasses several different relationships—from shared interest, to familial ties, friends, and acquaintances—so political similarity doesn"t necessarily exist in all such ties." This is not to say that Twitter"s creators should be preparing a Nobel Prize-winning speech. Far from it: The influence of its diversity is unknown. It could be that many people who see messages they disagree with simply change their behavior to screen out such material in future. But it shows that there is a potential to do something positive at Twitter. It"s clear there"s much work to be done. The researchers say they want to investigate a number of areas they"ve uncovered, having provided important insights at a time when politics seem more fractious and divided than ever.
2011.04.12
View 10797
Artificial Spore Production Technology Developed
The core technology needed in the development of ‘biosensors’ so crucial in diagnosing illnesses or pathogens was developed by Korean research team. KAIST’s Professor Choi In Seung of the department of Chemistry developed the technology that allows for the production of Artificial Spore by selectively coating a live cell. In the field of engineering the problem in developing the next generation bio sensor, the cell based sensor, was that it was difficult to keep a cell alive without division for a long time. Once a cell is taken out of the body, it will either divide or die easily. Professor Choi’s research team mimicked the spore, which has the capability to survive harsh conditions without division, and chemically coated a live cell and artificially created a cell similar to that of a spore. The physical and biological stabilities of the cell increased by coating an artificial shell over the yeast cell. The shell is composed with a protein similar to that of the protein that gives mussels its stickiness. In addition by controlling the thickness of the shell, the division rate of the yeast can be controlled. Professor Choi commented that this technology will serve as the basis for the single cell based biosensor. The research was conducted together with Professor Lee Hae Shin of KAIST department of Chemistry and Professor Jeong Taek Dong of Seoul National University’s department of Chemistry and was published as the cover paper of ‘Journal of the American Chemical Society’.
2011.04.01
View 11907
Professor Ko Kyu Young Appointed as a Distinguished Professor at KAIST
Professor Ko Kyu Young of the Graduate School of Medical Sciences was appointed as the Distinguished Professor at KAIST. Professor Ko is famous internationally for his work on the catalyst for blood vessel growth COMP-ANG1, and also for his research on blood vessel growth and lymph duct growth control. Professor Ko developed the Double Anti-Angiogenic Protein (DAAP) which effectively restricts the blood vessels from growing, opening a new approach to curing caner. The paper was published in ‘Cancer Cell’ as the cover paper (2010 August 17th edition) and is widely recognized as the marker that sums up the new paradigm of cure for cancer. In addition, his work on explaining how the new antigen interacts with the T-lymphocyte during a vaccination lead to the possibility of the increase of the efficiency of vaccination. The result of the research was published as the cover paper in ‘Immunity’ magazine. As is obvious to see his work with blood vessel growth and lymph duct growth and control is being published in major scientific journals. In addition he is continuously invited to international conferences as guest speakers and leader, effectively leading the field. As a result, he was appointed as the editor of ‘Blood’ magazine, the world’s best journal in the field of hematology and received ‘2010 KAISTian of the Year’ Award. The title Distinguished Professor is appointed to those who have made world-class research results and educational results and actively lead their respective field. They are provided with extra incentives and can even continue on with the professorship after retirement. It is only limited to 3% of the professors at KAIST and has to be someone recommended by the President, Vice-President, and the Deans of department and their worthiness is scrutinized by a foreign expert.
2011.03.25
View 10430
Interdisciplinary Research on World Environmental Problems with Humanities
KAIST’s Professor Michael Pak (department of Humanities and Social Sciences) has published a paper in ‘Environmental Science and Technology, ES&T’ and was made Lead Feature. His was the only paper published with a humanities background and his topic of discussion was ‘Environmentalism Then and Now: From Fears to Opportunities, 1970-2010’ in which he discussed the history of pro-environment activities, the patterns it showed, and its outlook. Professor Park noted that the problems and concerns over the environment is not a recent phenomenon. It took over 50 years for the environmental problems to resurface after being the ‘hot issue’ of the time during the industrial revolution in the 19th century. Professor Park deduced that there is a clear historical pattern. Professor Park insisted that the two areas of Environmental Research ‘Global Warming’ and ‘Change in Weather’. Especially because these two areas are rife with uncertainty as it is, and making policies based on inaccurate information is taking a gamble. Professor Park majored in history in UC Berkeley, received his masters’ and doctorate at Harvard University and was the professor at Massachusetts College of Art and Design before coming to KAIST at 2008.
2011.02.23
View 10569
New Bio-Clock gene and its function found
The Ministry of Education, Science and Technology announced that a Korean research team has found a new gene responsible for maintaining the bio-clock (twenty-four) and its mechanism. Twnety-four was led by Professor Choi Joon Ho and Dr. Lee Jong Bin of KAIST (department of Biology) and was a joint operation with Professor Ravi Allada and Dr.Lim Jeong Hoon of Northwestern University (department of neurobiology) and the result was published in ‘Nature’ magazine. The research team experimented with transformed small fruit flies for 4 years and found that there was an undiscovered gene that deals with the bio rhythm in the brain which they named ‘twenty-four’. The understanding with genes prior to twenty-four was that these genes regulate biorhythm in the transcription phase (DNA to mRNA). Twenty-four operates in the step after transcription when the ribosome creates proteins. Especially twenty-four has a great effect on the ‘period protein’ which acts as a sub-atomic clock that regulates the rhythm and life of each cell. The experiment was innovational in that it was able to scientifically prove the function of the protein produced by the gene. The result is expected to help solve the problems associated with sleep disorders, jetlags, eating rhythms, bio rhythms, etc. The name twenty-four was the fact that a day, a cycle, is 24 hours long and the gene’s serial numbers CG4857 adds up to twenty four.
2011.02.23
View 10948
<<
첫번째페이지
<
이전 페이지
21
22
23
24
25
26
27
28
>
다음 페이지
>>
마지막 페이지 28