SCIE
-
The MIT Skoltech Initiative Report identifies KAIST as one of the core group of emerging leaders for academic entrepreneurship and innovation
The Massachusetts Institute of Technology (MIT) Skoltech Initiative was established in 2011 to support MIT’s multi-year collaboration in building the Skolkovo Institute of Science and Technology (Skoltech), a private graduate research university in Skolkovo, Russia.
Recently, the office of the MIT Skoltech Initiative has published a benchmark report conducted from 2012 to 2014 by Dr. Ruth Graham, an internationally recognized leading consultant for engineering education and research as well as academic technology-driven entrepreneurship, under the guidance of MIT professors and the Center for Entrepreneurship and Innovation at the MIT Skoltech Initiative.
The report identified more than 200 institutions as the world’s most highly-regarded entrepreneurial universities and characterized the approach taken by them to build university-based ecosystems for entrepreneurship and innovation (E&I).
Among the top-ranked institutions, the report mentioned an emerging group of leaders (EGLs) that are “located within more challenging environments but establishing strong entrepreneurship and innovation profiles and reputations.” The report named, in particular, five universities, KAIST (Korea), Technion (Israel), Aalto University (Finland), the University of Michigan (US), and the University of Auckland (NZ), as the core group of the EGLs.
This benchmarking study was written to highlight key strategies and features associated with well-regarded university E&I transformations within more challenging environments and to address barriers and limits faced by the EGLs, thereby providing a good model to other universities wishing to make similar changes.
Through an in-depth case study of a small group of emerging universities, the report concluded that three major components play a critical role in the development of institutional E&I capacity and the growth of ecosystems for E&I:
Component 1: Inclusive grassroots community of E&I engagement across university populations and regional community;
Component 2: Strength in industry-funded research and licensing of university-owned technology; and
Component 3: University E&I agenda reflected in its policies, mission, budget allocations, incentives and curriculum
For more details, please visit the link below:
http://web.mit.edu/sktech/sktech-program/entrepreneurship-innovation/benchmark.html
2014.08.20 View 8299 -
Discovery of New Therapeutic Targets for Alzheimer's Disease
A Korean research team headed by Professor Dae-Soo Kim of Biological Sciences at KAIST and Dr. Chang-Jun Lee from the Korea Institute of Science and Technology (KIST) successfully identified that reactive astrocytes, commonly observed in brains affected by Alzheimer’s disease, produce abnormal amounts of inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) in reaction to the enzyme Monoamine oxidase B (Mao-B) and release GABA through the Bestrophin-1 channel to suppress the normal signal transmission of brain nerve cells.
By suppressing the GABA production or release from reactive astrocytes, the research team was able to restore the model mice's memory and learning impairment caused by Alzheimer’s disease. This discovery will allow the development of new drugs to treat Alzheimer’s and other related diseases.
The research result was published in the June 29, 2014 edition of Nature Medicine (Title: GABA from Reactive Astrocytes Impairs Memory in Mouse Models of Alzheimer’s Disease).
For details, please read the article below:
Technology News, July 10, 2014
"Discovery of New Drug Targets for Memory Impairment in Alzheimer’s Disease"
http://technews.tmcnet.com/news/2014/07/10/7917811.htm
2014.07.16 View 8381 -
Artificial Antibody-based Therapeutic Candidate for Lung Cancer Developed
Professor Hak-Sung Kim of Biological Sciences at KAIST publishes a cover article on artificial antibody in "Molecular Therapy".
Repebody-based lung cancer therapeutic drug candidate developed Repebody-based protein demonstrates the possibility of the development of a new drug
KAIST Biological Sciences Department’s Professor Hak-Sung Kim, in collaboration with Professor Eun-Kyung Cho from the College of Medicine at Chungnam National University, has successfully developed an artificial antibody-based, or repebody, cancer therapeutic candidate. These research results were published as a cover paper of the July edition of Molecular Therapy.
The repebody developed by Professor Kim and his team strongly binds to interleukin-6, a cancer-causing factor. It has also been confirmed that the repebody can significantly inhibit the proliferation of cancer cells in non-small-cell lung cancer animal model.
Numerous multinational pharmaceutical and biotechnology companies have invested astronomical amounts of money in research for the development of protein therapeutics with low side effects and high efficacy. More than 20 kinds of such therapeutics are currently under clinical trials, and over 100 drugs are under clinical demonstration. Among these, the majority is antibody-based therapeutics, and most of the investments are heavily concentrated in this field. However, antibody production cost is very high because it has large molecular weights and complex structural properties, and this makes it difficult to engineer. Consequently, the development costs a great deal of time and money.
In order to overcome the existing limitations of antibody-based therapeutics, Professor Kim and his team have developed a new artificial antibody, or repebody, which was published in Proceedings of the National Academy of Sciences (PNAS) in 2012. Based on this research, they have succeeded in developing a therapeutic candidate for treating non-small-cell lung cancer with a specifically strong cohesion to the cancer-causing factor, interleukin-6.
Interleukin-6 is a crucial substance within the body that is involved in immune and inflammatory-related signals. When abnormally expressed, it activates various carcinogenic pathways and promotes tumor growth and metastasis. Because of its importance, multinational pharmaceutical companies are heavily investing in developing therapeutics that can inhibit the signaling of interleukin-6.
In this study, Professor Kim and his team observed that a repebody consists of repeated modules, and they conceived a module-based affinity amplification technology that can effectively increase the binding affinity with the disease target. The developed therapeutic candidate has been confirmed in cell and animal experiments to show low immunogenicity, as well as to strongly inhibit the proliferation of non-small-cell lung cancer.
Furthermore, by investigating the complex structure of the repebody with interleukin-6, Professor Kim has identified its mechanism, which demonstrated the potential for therapeutic development. The researchers are currently carrying out pre-clinical trials for acquiring permission to perform clinical trials on animals with non-small-cell lung cancer. The repebody can be developed into a new protein drug after demonstrating its safety and efficacy.
Professor Hak-Sung Kim and his team have confirmed that the repebody can be utilized as a new protein drug, and this will be a significant contribution to Korea’s protein drugs and biotechnology industry development.
The research was supported by the Future Pioneer Industry project and sponsored by the Ministry of Science, ICT and Future Planning.
Figure 1. Professor Kim’s article published as the cover article of July edition of Molecular Therapy
Figure 2. Clinical proof of the repebody’s inhibition of cancer growth using animal models
2014.07.14 View 12121 -
Opening of "Education Donation Center" for Knowledge Sharing
KAIST is a leader in knowledge-sharing services for the educationally underprivileged. KAIST held the opening ceremony of the Education Donation Center at its Munji Campus on July 4, 2014 and was appointed as a “2014 Chungcheong-Gangwon province model local education donation center” sponsored by the Education Ministry of Korea and Korea Foundation for the Advancement of Science and Creativity.
The Education Donation Center (EDC) will integrate programs run by the Chungcheong-Gangwon province education donation organizations and introduce them to local chapter organizations. The EDC will recommend new donation organizations to the organizations in need. To ensure efficient donation, the EDC will consult programs of donation organizations. The EDC will also suggest regionally suitable education donation programs. KAIST will provide three staff members, six graduate students, and one to manage the career counselor to the center.
Joo-Sung Lee of the Business & Technology Management Department is the professor in charge of the EDC. He explained, “The center is the medium between the newly participating education donation organizations and the demand organizations. I will invest every effort to provide high-quality educational benefits to educationally underprivileged people."
KAIST has also been running an education service group called ‘Midam Scholarship’, an online education donation group called ‘Chalk’, and science camp programs for youth to establish the sharing and collaboration culture of KAIST.
2014.07.10 View 8100 -
Professor Haeng-Ki Lee appointed as "ICCES Distinguished Fellow"
Professor Haeng-Ki Lee
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering at KAIST has been appointed as “Distinguished Fellow” and has also received the “Outstanding Research Award” at the International Conference on Computational & Experimental Engineering and Sciences (ICCES).
Founded in 1986, ICCES is regarded as one of the most prestigious international conferences in the field of computational mechanics and experimental engineering.
The Nominating Committee at ICCES recommends the appointment of a distinguished member who has made significant contributions to the development of computational mechanics and experimental engineering. Professor Lee was the first Korean who received such title. Furthermore, he was the recipient of the “Outstanding Research Award” presented by ICCES for his academic research on damage mechanics of complex systems.
Professor Lee is currently serving as the Head of the Department of Civil and Environmental Engineering at KAIST and the Director of BK Plus Agency, a Korean government’s research program. He received an award from the Minister of Science, ICT and Future Planning in 2013 for the promotion of science and technology.
2014.07.02 View 10311 -
A KAIST startup, YBrain, builds a wearable device to cure Alzheimer's
A group of KAIST graduates from the Departments of Bio and Brain Engineering, Computer Science, Materials Science Engineering, and Industrial Design created a startup called YBrain (http://ybrain.com/). YBrain develops a wearable neuroscience technology to treat or reduce the symptoms of degenerative brain diseases such as dementia and Alzheimer’s. Their recent technological developments were covered in e27, one of the leading blogs based in Singapore. The blog covers topics like the latest technology innovation, startups, and entrepreneurship in Asia. A news article follows below:
e27, June 24, 2014
“This wearable tech may be able to combat effects of Alzheimer’s”
http://e27.co/this-wearable-tech-may-be-able-combat-effects-of-alzheimers-20140624/
2014.06.25 View 10872 -
KAIST doctoral student wins prize at 2014 International Military Science and Technology Fair
Min-Kyu Yoo (far left), a doctoral student in the Department of Materials Science Engineering, KAIST, received a silver prize at the 2014 International Military Science and Technology Fair held from May 29 to June 1, 2014 at KINTEX, Ilsan City, Korea.
Yoo presented a paper on aluminum composite materials that were reinforced by carbon nanotubes. Carbon nanotubes reinforced aluminum composite materials have strong mechanical properties, and some nations have used them to manufacture battle tanks.
Aluminum generates hydrogen in an alkaline solution. Utilizing this property and the galvanic corrosion of carbon nanotubes and aluminums, Yoo developed a hydrogen energy system that is fueled with composite materials of carbon nanotube reinforced aluminum. He produced 5 kW electric power and maintained it 22 days using 10 kg of the composite materials for a proton exchange membrane fuel cell and its auxiliary power system.
Yoo’s research will alleviate the difficulty of transporting fuels during wartime and can be applied to the development of an auxiliary power system for next generation aircrafts and battle tanks.
2014.06.24 View 8146 -
Professor Sang Ouk Kim Receives the "Scientist of the Month Award" from the Korean Government
Professor Sang Ouk Kim of the Department of Materials Science and Engineering, KAIST, received the Scientist of the Month Award in June 2014 for his development of a fundamental technology that allows free control of the properties of carbon-based materials.
Since June 1997, the Korean government has awarded monthly one scientist working in industry, universities, or research institutions to recognize his or her research achievements, as well as to promote science and technology.
Professor Kim implemented a technique known as doping, which has been used in ordinary semiconductor processes, to demonstrate the physical properties of carbon-based materials. Carbon nanotubes, graphene, and other carbon materials have superior mechanical and electrical properties and are regarded as next-generation materials. However, difficulty in controlling their qualities has made applications in various devices unfavorable. The doping technique in semiconductor production is to artificially introduce impurities into an extremely pure semiconductor for the purpose of modulating its electrical properties.
Profess Kim doped elements like nitrogen and boron to enable minute control of the physical properties of carbon-based materials and applied the technique to development of organic solar cells, organic light-emitting devices, and flexible memory. He also increased the application range by using a self-assembly method to change freely the structure of carbon-based materials.
Professor Kim has published 53 papers in renowned journals such as Advanced Materials and Nanoletters. He was rewarded further by being invited to write a review paper for the 25th anniversary special edition for Advanced Materials.
2014.06.19 View 9347 -
KAIST studnets win 2014 Creative Vitamin Project Competition
A team of KAIST students have won the grand prize for the “2014 Creative Vitamin Project Competition” held on May 28, 2014 in Seoul. The event was co-hosted by the Ministry of Science, ICT and Future Planning, National Information Society Agency, and Korea IT Convergence Technology Association. The Creative Vitamin Project is the Korean government’s initiative to grow the Korean economy and generate job creation by applying science and technology, information and communications technology in particular, to the existing industry and social issues.
The winners were Hyeong-Min Son, a student in the master’s program in the Department of Civil and Environmental Engineering, KAIST and Su-Yeon Yoo, a Ph.D. student from the Graduate School of Information Security, KAIST.
Son and Yoo proposed a sustainable crop protection system using directional speakers. This technique not only efficiently protects crops from harmful animals, but also effectively guides the animals outside the farmland.
Kwang-Soo Jang, the Director of the National Information Society Agency, said, “This competition provides an opportunity to develop public consensus and interest in the Creative Vitamin Project. We hope that through the participation of all citizens, the project can become an instrument to realizing the creative economy.”
2014.06.18 View 9706 -
Professor Sung Yong Kim Appointed as Committee Member to Serve PICES
The Pacific International Council for the Exploration of the Sea: North Pacific Marine Science Organization (PICES) is an intergovernmental organization, which was established in 1992 to promote and coordinate marine research in the North Pacific and adjacent areas. Currently, the United States, Canada, Japan, China, Russia, and Korea are members of the organization.
Professor Sung Yong Kim of Ocean Systems Engineering, KAIST, has been appointed to serve the Scientific and Technical Committees of PICES. He will begin his stint from July 1, 2014. During his assignment, Professor Kim will identify the need for observation of the North Pacific marine environment, develop observation methodology, and publish an annual report on the observation.
Professor Kim is an expert in marine physics and environmental fluids, with a focus on coastal circulation and dynamics, mesoscale and submesoscale eddies, integrated coastal ocean observing system, and statistical and dynamic data analysis.
2014.06.18 View 7638 -
Professor YongKeun Park Produces Undergraduate Students with International Achievements
Three undergraduate students under the supervision of Professor YongKeun Park from the Department of Physics, KAIST, have published papers in globally renowned academic journals.
The most recent publication was made by YoungJu Jo, a senior in physics. Jo’s paper entitled “Angle-resolved light scattering of individual rod-shaped bacteria based on Fourier transform light scattering” was published in the May 28th edition of Scientific Reports.
Analyzing bacteria is a very important task in the field of health and food hygiene, but using the conventional biochemical methods of analysis takes days. However, observation with Jo’s newly developed method using light scattering analyzes bacteria within a matter of seconds.
SangYeon Cho from the Department of Chemistry also published papers in Cell (2012) and Nature (2013), respectively, under the guidance of Professor Park. SangYeon Cho’s outstanding research achievements were recognized by Harvard and MIT. He was accepted with a full scholarship to Harvard-MIT Health Sciences and Technology Graduate School. He will begin his graduate studies at Harvard-MIT this September.
Last March, SeoEun Lee from the Department of Biology was the recipient of the Best Paper Award by the Optical Society of Korea. She plans to pursue a doctoral degree at the College of Physicians and Surgeons, Columbia University in New York.
Professor Park said, “Undergraduate students, who are learning a variety of subjects concurrently, are at the most creative time of their lives. KAIST has offered many opportunities to undergraduate students to partake in various research programs.”
- Picture (a) and (b): Rod-shaped bacteria’s phase image and light-scattering patterns
- Picture (c): Quantitative analysis to illustrate the extraction of information from bacteria
2014.06.03 View 11392 -
Clear Display Technology Under Sunlight Developed
The late Professor Seung-Man Yang
The last paper of the late Professor Seung-Man Yang, who was a past master of colloids and fluid mechanics
Practical patterning technology of the next generation optical materials, photonic crystals
The mineral opal does not possess any pigments, but it appears colorful to our eyes. This is because only a particular wavelength is reflected due to the regular nano-structure of its surface. The material that causes selective reflection of the light is called photonic crystals.
The deceased Professor Seung-Man Yang and his research team from KAIST’s Chemical and Biomolecular Engineering Department ha ve developed micro-pattern technology using photolithographic process. This can accelerate the commercialization of photonic crystals, which is hailed as the next generation optics material.
The research results were published in the April 16th edition of Advanced Materials, known as the most prestigious world-renowned journal in the field of materials science.
The newly developed photonic crystal micro-pattern could be used as a core material for the next generation reflective display that is clearly visible even under sunlight. Since it does not require a separate light source, a single charge is enough to last for several days.
Until now, many scientists have endeavored to make photonic crystals artificially, however, most were produced in a lump and therefore lacked efficiency. Also, the low mechanical stability of the formed structure prevented from commercialization.
In order to solve these problems, the research team has copied the nano-structure of opals.
Glass beads were arranged in the same nano-structure as the opal on top of the photoresist material undergoing photocuring by ultraviolet light. The glass beads were installed in the photoresist materials, and UV light was selectively exposed on micro regions. The remaining region was developed by photolithographic process to successfully produce photonic crystals in micro-patterns.
The co-author of the research, KAIST Chemical and Biomolecular Engineering Department’s Professor Sin-Hyeon Kim, said, “Combining the semiconductor process technology with photonic crystal pattern technology can secure the practical applications for photonic crystals.”He also predicted “This technology can be used as the key optical material that configures the next generation reflective color display device with very low power consumption.”
The late Professor Seung-Man Yang was a world-renowned expert in the field of colloids and fluid mechanics. Professor Yang published over 193 papers in international journals and continued his research until his passing in last September.
He received Du Pont Science and Technology Award in 2007, KAIST Person of the Year 2008, Gyeong-Am Academy Award in 2009, as well as the President’s Award of the Republic of Korea in March 2014. The researchers devoted the achievement of this year’s research to Professor Yang in his honor.
Research was conducted by KAIST Photonic-fluidic Integrated Devices Research Team, as a part of the Creative Research Program funded by the Ministry of Science, ICT and Future Planning, Republic of Korea.
Figure 1. Opal [left] and the nano glass bead arrangement structure within the opal [right]
Figure 2. Process chart of the photonic crystal micro-pattern formation based on photolithography
Figure 3. Opal structure [left] and inverted structure of the opal [right]
Figure 4. Photonic crystal micro-pattern in solid colors
Figure 5. Photonic crystal micro-pattern that reflects two different crystals (Red, Green) [left] and pixelated pattern of photonic crystal in three primary colors (Red, Green, Blue) [right] that is applicable to reflective displays
2014.05.14 View 11371