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KAIST Unveils the Hidden Control Architecture of Brain Networks
(Professor Kwang-Hyun Cho and his team) A KAIST research team identified the intrinsic control architecture of brain networks. The control properties will contribute to providing a fundamental basis for the exogenous control of brain networks and, therefore, has broad implications in cognitive and clinical neuroscience. Although efficiency and robustness are often regarded as having a trade-off relationship, the human brain usually exhibits both attributes when it performs complex cognitive functions. Such optimality must be rooted in a specific coordinated control of interconnected brain regions, but the understanding of the intrinsic control architecture of brain networks is lacking. Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering and his team investigated the intrinsic control architecture of brain networks. They employed an interdisciplinary approach that spans connectomics, neuroscience, control engineering, network science, and systems biology to examine the structural brain networks of various species and compared them with the control architecture of other biological networks, as well as man-made ones, such as social, infrastructural and technological networks. In particular, the team reconstructed the structural brain networks of 100 healthy human adults by performing brain parcellation and tractography with structural and diffusion imaging data obtained from the Human Connectome Project database of the US National Institutes of Health. The team developed a framework for analyzing the control architecture of brain networks based on the minimum dominating set (MDSet), which refers to a minimal subset of nodes (MD-nodes) that control the remaining nodes with a one-step direct interaction. MD-nodes play a crucial role in various complex networks including biomolecular networks, but they have not been investigated in brain networks. By exploring and comparing the structural principles underlying the composition of MDSets of various complex networks, the team delineated their distinct control architectures. Interestingly, the team found that the proportion of MDSets in brain networks is remarkably small compared to those of other complex networks. This finding implies that brain networks may have been optimized for minimizing the cost required for controlling networks. Furthermore, the team found that the MDSets of brain networks are not solely determined by the degree of nodes, but rather strategically placed to form a particular control architecture. Consequently, the team revealed the hidden control architecture of brain networks, namely, the distributed and overlapping control architecture that is distinct from other complex networks. The team found that such a particular control architecture brings about robustness against targeted attacks (i.e., preferential attacks on high-degree nodes) which might be a fundamental basis of robust brain functions against preferential damage of high-degree nodes (i.e., brain regions). Moreover, the team found that the particular control architecture of brain networks also enables high efficiency in switching from one network state, defined by a set of node activities, to another – a capability that is crucial for traversing diverse cognitive states. Professor Cho said, “This study is the first attempt to make a quantitative comparison between brain networks and other real-world complex networks. Understanding of intrinsic control architecture underlying brain networks may enable the development of optimal interventions for therapeutic purposes or cognitive enhancement.” This research, led by Byeongwook Lee, Uiryong Kang and Hongjun Chang, was published in iScience (10.1016/j.isci.2019.02.017) on March 29, 2019. Figure 1. Schematic of identification of control architecture of brain networks. Figure 2. Identified control architectures of brain networks and other real-world complex networks.
2019.04.23
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KAIST-KU Joint Research Center for Smart Healthcare & Transportation
(President Shin shakes hands with KU acting Presidedent Arif Al Hammdi at the KAIST-KU Joint Research Center opening ceremony on April 8.) KAIST opened the KAIST-Khalifa University Joint Research Center with Khalifa University on April 8. The opening ceremony was held at Khalifa University and was attended by President Sung-Chul Shin and Khalifa University Acting President Arif Al Hammadi. The new research center reflects the evolution of the long-established partnership between the two institutions. The two universities have already made very close collaborations in research and education in the fields of nuclear and quantum engineering. The launch of this center expanded their fields of collaboration to smart healthcare and smart transportation, key emerging sectors in the Fourth Industrial Revolution. President Shin signed an MOU with the UAE Minister of State for Advanced Science Sarah Amiri and Khalifa University to expand mutual collaboration in technology development and fostering human capital last year. The center will conduct research and education on autonomous vehicles, infrastructure for autonomous vehicle operation, wireless charging for electric vehicles, and infrastructure for electric autonomous vehicles. As for smart healthcare, the center will focus on healthcare robotics as well as sensors and wearable devices for personal healthcare services. President Shin, who accompanied a research team from the Graduate School of Green Transportation, said, “We are very delighted to enter into this expanded collaboration with KU. This partnership justifies our long-standing collaboration in the areas of emerging technologies in the Fourth Industrial Revolution while fostering human capital.” KU Acting President Arif Al Hammadi added, “The outcome of these research projects will establish the status of both institutions as champions of the Fourth Industrial Revolution, bringing benefits to our communities. We believe the new research center will further consolidate our status as a globally active, research-intensive academic institution, developing international collaborations that benefit the community in general.”
2019.04.09
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Blue-enriched White Light to Wake You Up in the Morning
(from left: Professor Hyun Jung Chung, Professor Hyeon-Jeong Suk, Taesu Kim and Professor Kyungah Choi) Here is a good news for those of who have difficulty with morning alertness. A KAIST research team proposed that a blue-enriched LED light can effectively help people overcome morning drowsiness. This study will provide the basis for major changes in future lighting strategies and thereby help create better indoor environments. Considerable research has been devoted to unmasking circadian rhythms. The 2017 Nobel Prize in Physiology or Medicine went to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for unveiling the molecular mechanisms that control circadian rhythms. In particular, the relationship between light and its physiological effects has been investigated since the discovery of a novel, third type of photoreceptor in the human retina in the early 2000s. Rods and cones regulate visual effects, while the third type, photosensitive retinal ganglion cells, regulate a large variety of biological and behavioral processes including melatonin and cortisol secretion, alertness, and functional magnetic resonance imaging (fMRI). Initial studies on light sources have shown that blue monochromatic, fully saturated lights are effective for stimulating physiological responses, but the relative effectiveness of commercially available white light sources is less well understood. Moreover, the research was more focused on the negative effects of blue light; for instance, when people are exposed to blue light at night, they have trouble achieving deep sleep because the light restrains melatonin secretion. However, Professor Hyeon-Jeong Suk and Professor Kyungah Choi from the Department of Industrial Design and their team argue that the effects of blue-enriched morning light on physiological responses are time dependent, and that it has positive effects on melatonin levels and the subjective perception of alertness, mood, and visual comfort compared with warm white light. The team conducted an experiment with 15 university students. They investigated whether an hour of morning light exposure with different chromaticity would affect their physiological and subjective responses differently. The decline of melatonin levels was significantly greater after the exposure to blue-enriched white light in comparison with warm white light. Professor Suk said, “Light takes a huge part of our lives since we spend most of our time indoors. Light is one of the most powerful tools to affect changes in how we perceive and experience the environment around us.” Professor Choi added, “When we investigate all of the psychological and physiological effects of light, we see there is much more to light than just efficient quantities. I believe that human-centric lighting strategies could be applied to a variety of environments, including residential areas, learning environments, and working spaces to improve our everyday lives.” This research was collaborated with Professor Hyun Jung Chung from the Graduate School of Nanoscience and Technology and was published in Scientific Reports (10.1038/s41598-018-36791-5) on January 23, 2019. Figure 1. Changes in melatonin secretion during day and night time
2019.03.06
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KAIST 2019 Commencement at a Glance
(KAIST 2019 Commencement Ceremony) This year, KAIST awarded a total of 2,705 degrees: 654 PhD degrees, 1,255 master’s degrees, and 796 bachelor’s degrees. Including this year’s numbers, KAIST has conferred a total of 63,830 degrees since its foundation in 1971. Parents, family, and friends came to campus to congratulate the graduates with big smiles and hugs. Faculty and staff members also attended the ceremony to celebrate their graduation. This year, distinguished guests including National Assembly Member Kyung-Jin Kim and Vice Minister for Science, Technology and Innovation Dae-sik came to celebrate the day with the KAIST community. During the commencement, KAIST also announced the recipients of its undergraduate academic awards. The Minister of Science and ICT Award was won by Do-Yoon Kim from the Department of Aerospace Engineering, the KAIST Board of Trustee Chairperson Award went to Se-rin Lee from the Department of Materials Science and Engineering, the KAIST Presidential Award was won by Hee-Ju Kim from the Department of Physics, the KAIST Alumni Association President Award went to Hyeon-Seong Park from the School of Electrical Engineering, and finally the KAIST Development Foundation Chairperson Award was won by Gyeong-Hoon Lee from the Department of Mathematical Sciences. This year’s valedictorian Eun-Seok Jeong from the School of Computing said, “I believe that we are able to stand here today because we challenged ourselves to confront our shortcomings and our uncertainty. If we continue to develop, we will become a better person than we were yesterday.” (KAIST President Sung-Chul Shin and Woo-Seok Jeong, '19 PhD in Aerospace Engineering) As a KAIST alumnus and fellow scientist, President Sung-Chul Shin offered his congratulations and emphasized that graduates should continue to pursue the C³ spirit. “In this age of great transformation, embrace challenges and exercise creativity as you have learnt through your education and research at KAIST. And keep in mind the importance of caring for others. Please remember that challenge and creativity will have more meaning if rendered with a caring spirit,” he said.
2019.02.15
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First Korean Member of OceanObs' Organizing Committee
Professor Sung Yong Kim from the Department of Mechanical Engineering became the first Korean to be elected as an organizing committee member of the international conference OceanObs’19’, specializing in the ocean observing field. Professor Kim has been actively engaged in advisory panels, technical committees, and working groups for the North Pacific Marine Science Organization (PICES). Through numerous activities, he was recognized for his professionalism and academic achievements, which led him to be appointed as a member of the organizing committee. The organizing committee is comprised of leading scholars and researchers from 20 countries, and Professor Kim will be the first Korean scientist to participate on the committee. Since 1999, the conference has been held every decade. Global experts specializing in oceanic observation gather to discuss research directions for the next ten years by monitoring physical, biological, and chemical variables in regional, national, and global oceans and applying marine engineering. This year, approximately 20 institutes including NASA’s Jet Propulsion Laboratory (JPL), the National Science Foundation, the National Oceanic and Atmospheric Administration, and the European Space Agency will support funds as well as high-tech equipment to the conference. This year’s conference theme is the governance of global ocean observing systems such as underwater gliders, unmanned vehicles, remote sensing, and observatories. The conference will hold discussions on monitoring technology and information systems to ensure human safety as well as to develop and preserve food resources. Additionally, participants will explore ways to expand observational infrastructures and carry out multidisciplinary approaches. There will also be collaborations with the Global Ocean Observing System (GOOS) and the Partnership for Observation of the Global Oceans (POGO) to organize ocean observing programs and discuss priorities. Finally, they will set a long-term plan for solving major scientific issues, such as climate change, ocean acidification, energy, and marine pollution. Professor Kim said, “Based on the outcomes drawn from the conference, I will carry out research on natural disasters and climate change monitoring by using unmanned observing systems. I will also encourage more multidisciplinary research in this field.”
2019.01.25
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New Members of KAST and Y-KAST 2019
(Professor Eui-Cheol Shin from the Graduate School of Medical Science and Engineering) Professor Eui-Cheol Shin from the Graduate School of Medical Science and Engineering became a new fellow of the Korean Academy of Science and Technology (KAST) along with 25 other scientists in Korea. He is one of the top virus immunologists in Korea and has published a review article in Nature Reviews Immunology. Meanwhile KAST selected and announced 26 young scientists under the age 43 who have shown great potential and the creativity to carry out next-generation research. The list of Y-KAST (Young Korean Academy of Science and Technology) includes six KAIST professors: Professor Ji Oon Lee from the Department of Mathematical Sciences, Professor Mi Hee Lim from the Department of Chemistry, Professor Shin-Hyun Kim from the Department of Chemical and Biomolecular Engineering, Professor Jung-Ryul Lee from the Department of Aerospace Engineering, Professor Hyunjoo Jenny Lee from the School of Electrical Engineering, and Professor Yeon Sik Jung from the Department of Materials Science and Engineering. KAST conferred their fellowships and Y-KAST membership during the New Year Reception.
2019.01.22
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Sound-based Touch Input Technology for Smart Tables and Mirrors
(from left: MS candidate Anish Byanjankar, Research Assistant Professor Hyosu Kim and Professor Insik Shin) Time passes so quickly, especially in the morning. Your hands are so busy brushing your teeth and checking the weather on your smartphone. You might wish that your mirror could turn into a touch screen and free up your hands. That wish can be achieved very soon. A KAIST team has developed a smartphone-based touch sound localization technology to facilitate ubiquitous interactions, turning objects like furniture and mirrors into touch input tools. This technology analyzes touch sounds generated from a user’s touch on a surface and identifies the location of the touch input. For instance, users can turn surrounding tables or walls into virtual keyboards and write lengthy e-mails much more conveniently by using only the built-in microphone on their smartphones or tablets. Moreover, family members can enjoy a virtual chessboard or enjoy board games on their dining tables. Additionally, traditional smart devices such as smart TVs or mirrors, which only provide simple screen display functions, can play a smarter role by adding touch input function support (see the image below). Figure 1.Examples of using touch input technology: By using only smartphone, you can use surrounding objects as a touch screen anytime and anywhere. The most important aspect of enabling the sound-based touch input method is to identify the location of touch inputs in a precise manner (within about 1cm error). However, it is challenging to meet these requirements, mainly because this technology can be used in diverse and dynamically changing environments. Users may use objects like desks, walls, or mirrors as touch input tools and the surrounding environments (e.g. location of nearby objects or ambient noise level) can be varied. These environmental changes can affect the characteristics of touch sounds. To address this challenge, Professor Insik Shin from the School of Computing and his team focused on analyzing the fundamental properties of touch sounds, especially how they are transmitted through solid surfaces. On solid surfaces, sound experiences a dispersion phenomenon that makes different frequency components travel at different speeds. Based on this phenomenon, the team observed that the arrival time difference (TDoA) between frequency components increases in proportion to the sound transmission distance, and this linear relationship is not affected by the variations of surround environments. Based on these observations, Research Assistant Professor Hyosu Kim proposed a novel sound-based touch input technology that records touch sounds transmitted through solid surfaces, then conducts a simple calibration process to identify the relationship between TDoA and the sound transmission distance, finally achieving accurate touch input localization. The accuracy of the proposed system was then measured. The average localization error was lower than about 0.4 cm on a 17-inch touch screen. Particularly, it provided a measurement error of less than 1cm, even with a variety of objects such as wooden desks, glass mirrors, and acrylic boards and when the position of nearby objects and noise levels changed dynamically. Experiments with practical users have also shown positive responses to all measurement factors, including user experience and accuracy. Professor Shin said, “This is novel touch interface technology that allows a touch input system just by installing three to four microphones, so it can easily turn nearby objects into touch screens.” The proposed system was presented at ACM SenSys, a top-tier conference in the field of mobile computing and sensing, and was selected as a best paper runner-up in November 2018. (The demonstration video of the sound-based touch input technology)
2018.12.26
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KAIST Shows Strong Performance in Crypto Contest Korea 2018
(Awardees at the ceremony for Crypto Contest Korea 2018) A paper titled “Indifferentiability of Truncated Random Permutations” by PhD candidate Wonseok Choi and MS candidate Byeonghak Lee (under Professor Jooyoung Lee) from the KAIST Graduate School of Information Security (GSIS) won first place in Crypto Contest Korea 2018. Byeonghak Lee became a repeat winner since his paper titled “Tweakable Block Ciphers Secure Beyond the Birthday Bound in the Ideal Cipher Model” also received an award at Crypto Contest Korea 2017. The contest, hosted by the Korea Cryptography Forum, the Korea Institute of Information Security & Cryptology, and the National Security Research Institute and sponsored by the National Intelligence Service, was held for promoting cryptography in Korea. The total prize money is fifty million won with ten million won going to the first place winners. The contest was divided into three divisions: paper, problem solving, and idea. Among the three divisions, first place came from the paper division only. Besides first place, KAIST students showed outstanding performance in the contest. PhD candidate Seongkwang Kim received participation prize while he also received special prizes with MS candidate Yeongmin Lee. The hacking club GoN (under Professor Sang Kil Cha), comprised of undergraduate students from the GSIS was awarded the grand prize in the division of problem solving. The award ceremony was held during the Future Crypto Workshop 2018 on November 15. The awards ceremony for Crypto Expert Korea 2018 were also held there, and PhD candidate Ji-Eun Lee from the School of Computing and Byeonghak Lee received awards, the grand prize and runner-up prize respectively.
2018.11.27
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KAIST Launches Woorisae II
Professor Sejin Kwon from the Department of Aerospace Engineering and his team succeeded in launching a science rocket, named ‘Woorisae II’ at Saemanguem reclamation. This rocket was developed in collaboration with the Satellite Technology Research Lab (SaRTec). The test-firing was conducted at 10:43 am on Sunday October 28, 2018 (35°N 42’ 06” 126°E 33’ 36”, Radius of 0.6NM). This launch was the follow-up to the previous launch that was cancelled due to not gaining approval for using the airspace. Professor Kwon’s team put a great deal of effort into securing the land for the rocket launch. As a result, they got approval from the Saemangeum Development and Investment Agency for the land and the Ministry of Land, Infrastructure and Transport for the use of the airspace. The Republic of Korea Air Force and United States Air Force also approved the use of the airspace for the launch of the science rocket for research purposes. Woorisae II is 2.2 meters long with a diameter of 20cm, and weighs 13kg without a payload. The rocket is powered by a hybrid rocket with hydrogen peroxide oxidizer producing 100 kg of force. The Woorisae II sounding rocket was designed to burn for five seconds and then continue inertial flight for 20 seconds. The target altitude of Woorisae II was set at 3,300 feet to comply with the airspace approval. The team developed the core components, including a hybrid rocket propulsion system, flight computer and parachute recovery system, as well as a ground control station. The flight data was transmitted to the ground station and recorded to onboard computer memory. When a malfunction occurs during the flight, Woorisae II was designed to terminate the power flight for safety by shutting the propellant valve and deploying the recovery parachute. All the rocket subsystems and components were developed and supplied by domestic startup companies such as INOCOM and NARA SPACE TEHCNOLOGY. Generally, sounding rockets reach an altitude beyond 30km and are widely used for testing rocket engines and reentry materials as well as for conducting microgravity experiments. Instruments for atmospheric science can also be installed to measure fine dust and high altitude atmosphere. Besides these science and technology purposes, most advanced spacefaring countries have sounding rocket programs to train and educate young people in the field of space science. Professor Kwon said, “We will plan to launch upgraded rockets on November 4 and December 6 because we already received approval from the related agencies for using this land and airspace. Based on the experiment, we are planning to develop a cost-efficient small launch vehicle that is capable of delivering a cube satellite into Earth’s orbit.” (Photos of preparing the rocket launch)
2018.10.29
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AI |QC ITRC Opens at KAIST
(from left: Dean of College of Engineering Jong-Hwan Kim, Director of AI│QC ITRC June-Koo Rhee, Vice President for R&DB Heekyung Park and Director General for Industrial Policy Hong Taek Yong) Artificial Intelligence|The Quantum Computing Information Technology Research Center (AI|QC ITRC) opened at KAIST on October 2. AI|QC ITRC, established with government funding, is the first institute specializing in quantum computing. Three universities (Seoul National University, Korea University, and Kyung Hee University), and four corporations, KT, Homomicus, Actusnetworks, and Mirae Tech are jointly participating in the center. Over four years, the institute will receive 3.2 billion KRW of research funds. Last April, KAIST selected quantum technology as one of its flagship research areas. AI|QC ITRC will dedicate itself to developing quantum computing technology that provides the computability required for human-level artificial intelligence. It will also foster leaders in related industries by introducing industry-academic educational programs in graduate schools. QC is receiving a great deal of attention for transcending current digital computers in terms of computability. World-class IT companies like IBM, Google, and Intel and ventures including D-Wave, Rigetti, and IonQ are currently leading the industry and investing heavily in securing source technologies. Starting from the establishment of the ITRC, KAIST will continue to plan strategies to foster the field of QC. KAIST will carry out two-track strategies; one is to secure source technology of first-generation QC technology, and the other is to focus on basic research that can preoccupy next-generation QC technology. Professor June-Koo Rhee, the director of AI│QC ITRC said, “I believe that QC will be the imperative technology that enables the realization of the Fourth Industrial Revolution. AIQC ITRC will foster experts required for domestic academia and industries and build a foundation to disseminate the technology to industries.” Vice President for R&DB Heekyung Park, Director General for Industrial Policy Hong Taek Yong from the Ministry of Science and ICT, Seung Pyo Hong from the Institute for Information & communications Technology Promotion, Head of Technology Strategy Jinhyon Youn from KT, and participating companies attended and celebrated the opening of the AI│QC ITRC.
2018.10.05
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Scientist of October, Professor Haeshin Lee
(Professor Haeshin Lee from the Department of Chemistry) Professor Haeshin Lee from the Department of Chemistry received the ‘Science and Technology Award of October’ from the Ministry of Science and ICT and the National Research Foundation of Korea for his contribution to developing an antibleeding injection needle. This novel outcome will fundamentally prevent the problem of secondary infections of AIDS, Ebola and Hepatitis viruses transmitting from patients to medical teams. This needle’s surface is coated with hemostatic materials. Its concept is simple and the key to this technology is to make materials that are firmly coated on the needle so that they can endure frictional force when being injected into skin and blood vessels. Moreover, the materials should be adhesive to skin and the interior of blood vessels, but harmless to humans. Professor Lee found a solution from natural polymer ingredients. Catecholamine can be found in mussels. Professor Lee conjugated catechol groups on the chitosan backbone. He applied this mussel-inspired adhesive polymer Chitosan-catechol, which immediately forms an adhesive layer with blood, as a bioadhesion for the antibleeding injection needle. Professor Lee said, “Chitosan-catechol, which copies the adhesive mechanism of mussels, shows high solubility in physiological saline as well as great mucoadhesion. Hence, it is perfectly suitable for coating the injection needle. Combining it with proteins allows for efficient drug delivery to the heart, which is a challenging injection location, so it will be also useful for treating incurable heart disease.”
2018.10.05
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President Shin Presents Opportunities & Challenges of the 4IR at the Summer Davos Forum
(President Shin makes a keynote speech at the 2018 Summer Davos Forum in China on Sept.20.) KAIST co-hosted the Asia Session with the World Economic Forum during the 2018 Summer Davos Forum in Tianjin, China from September 18 through 20. The session highlighted regional collaboration in Asia to promote inclusive growth in the Fourth Industrial Revolution. KAIST is working closely with the WEF to take the lead in the Fourth Industrial Revolution. Last July, KAIST established the Fourth Industrial Revolution Information Center (FIRIC) at the KAIST Institute and signed an MOU with the Center for the Fourth Industrial Revolution (C4IR) at the WEF in October. The session is a follow-up event KAIST and the C4IR agreed to last year during the Roundtable Session held in Seoul. Many experts in new emerging industries as well as many project directors, including Director Murat Sonmez of the C4IR, attended the session KAIST hosted. Director Chizuru Suga at the C4IR in Japan, Director Danil Kerimi in China, and Director Shailesh Sharda in India also attended the session and discussed ways to expand collaboration and networks among the countries. In his keynote speech at the session on September 20, President Sung-Chul Shin presented how the Korean government is trying to drive the economy by strategically investing in focused industries in the new global industrial environment. President Shin introduced the government’s strategic roadmap to build the competitiveness of emerging technologies such as AI, blockchain, and precision medicine. He also stressed that the three components of innovation, collaboration, and speed should be prioritized in all sectors for the successful realization of the Fourth Industrial Revolution. For instance, innovation in education, research, and technology commercialization, expansive domestic and international collaboration beyond the private and public sectors, speedy deregulation, and efficient governance will all be critical. He also said that KAIST will launch new pilot collaboration projects along with the WEF soon. “We paved the way for leading the network with major countries including Japan and India for advancing the Fourth Industrial Revolution through this session,” President Shin said.
2018.09.21
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