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KAIST to Open Liaison Office in Silicon Valley
KAIST will open a liaison office in Silicon Valley, California, within the first half of this year to serve as a beachhead of its operations in the United States, university authorities announced Monday. The opening of "KAIST America" office will be financially supported by the Silicon Valley-based Ambex Venture Group. The liaison office will be located at the first floor of the AmBex building in Sunnyvale. The liaison office will be responsible for overseeing joint research between KAIST and the U.S. National Aeronautics and Space Administration (NASA) and KAIST"s other cooperative projects in research and development with enterprises and universities in Silicon Valley. It will also be engaged in forming a network among KAIST alumni members in the United States, raising funds within the U.S. and managing the money. The office will arrange KAIST students" internship in the companies in Silicon Valley. "KAIST America is part of the globalization strategies that KAIST has pursued consistently. It is aimed at helping set up venture firms based on the technologies that KAIST has developed so far and generating funds needed for further development of the university," said Sun-Heung Jang, KAIST vice president. AmBex, a venture capital company that invests in information technology, health science and financial service firms, was founded by Jong-Moon Lee, a member of Presidents" Advisory Council at KAIST. The AmBex building is situated near Stanford University, University of California in Berkeley, Google and Yahoo. KAIST President Nam Pyo Suh will invite Stanford and UC Berkeley professors, executives of Silicon Valley enterprises and KAIST alumni in the area to the opening ceremony of the liaison office to be held some time in the first half of this year.
2008.03.25
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Prof. Kim Receives Lee Osheroff Prize
Professor Eun-Seong Kim of the Department of Physics has been selected as the winner of the Lee Osheroff Richardson Prize for 2008. The award was established in honor of the 1996 Nobel Prize laureates in Physics David Lee, Douglas Osheroff, and Robert Richardson for their discovery in superfluidity in helium-3. The annual prize sponsored by Oxford Instruments NanoScience is awarded to a young scientist who has made a notable achievement in the field of low temperatures and high magnetic fields. Kim was chosen as the winner of this prestigious award for his contributions to the understanding of solid helium. Through research, Professor Kim found superfluid-like behavior in solid helium and with this discovery it is shown that all three states of matter can exhibit superfluid behavior. The Lee Osheroff Richardson Prize recipient is selected by the North American Prize Committee which is composed of prominent figures in the low temperature and high magnetic fields including Professor Bruce Gaulin of McMaster University, who chairs the Prize Committee. The award ceremony was held on March 11 in New Orleans.
2008.03.18
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KAIST to Build Branch Campus in New Administrative City
KAIST signed a memorandum of understanding (MOU) with the Multifunctional Administrative City Construction Agency and the Korea Land Corporation on March 4 to build a branch campus in the city now under construction to house many government organizations to be relocated from Seoul. The MOU calls for building a well-facilitated KAIST campus on 310,000 square meters of land within the planned city, about 30 kilometers west of Daejeon. The multifunctional city, named Sejong City, is scheduled to be dedicated in 2014. The MAC now being built in the Yongi-Gongju area of South Chungcheong Province is geographically in the center of South Korea, and many governmental agencies and major public organizations will move in from 2015. The KAIST campus is envisioned to be home to a newly established College of Strategy and Policy, a Strategy and Policy Research Center, and an Innovative Technology Research Center. The College of Medical Science currently based in the Daejeon campus will be relocated to the campus. With a research-oriented hospital and a medical engineering research center, KAIST hopes to become a leading institution in disease treatment and medical engineering technologies. The new campus is also expected to house new KAIST colleges now in the planning stage which will offer interdisciplinary courses such as the College of IT and Contents and the College of Life Sciences. KAIST also seeks to resolve housing shortage problems by building an in-campus village designed to provide international living environment for professors and students on the planned campus
2008.03.18
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KAIST, K-Water Sign MOU for Cooperation in EEWS
KAIST has signed a memorandum of understanding with the Korea Water Resources Corporation (K-Water), a state-invested organization responsible for the development and management of inland water resources, for cooperation in the research on the four global issues of energy, environment, water and sustainability (EEWS). The MOU was signed by KAIST President Suh Nam-Pyo and K-Water President Kwak Kyul-ho on Feb. 22 at the KAIST. KAIST and K-Water agreed to establish a cooperative network for exchanges of personnel and research resources for advanced R&D on EEWS. The agreement has been reached on the common belief that EEWS is the most imminent problem facing the humanity in the 21st century. Under the MOU, KAIST and K-Water will work together to build a EEWS global network; to develop policies and conduct researches to strengthen the competitiveness of Korea"s water industry; and to train and exchange research manpower of the two institutions. The agreement also calls for sharing technological information, exchanging research results and publications; and jointly hosting symposiums and workshops.
2008.03.09
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KAIST Retains Top Spot in Systems and Software Engineering
For two consecutive years, KAIST, Korea"s top science and technology university, topped the list of the world"s most published institutions in the field of systems and software engineering, according to a survey conducted by the Journal of Systems and Software. The survey assessed systems and software engineering scholars and institutions by the number of papers they published in six major journals of the field from 2001 to 2005. Geographically, seven of the top 15 institutions are from the Asia-Pacific region, six from the United States and two from Europe. In previous assessments, institutions from the Americas took the lion"s share. KAIST topped the list of 15 in 2006 and again in 2007. The runner-up for 2007 is China"s National Chiao Tung University. Norway"s Simula Research Laboratory and Korea"s Seoul National University were ranked third and fourth, respectively. Rounding up the top ten list are Carnegie Mellon University, Georgia Institute of Technology, Iowa State University, and University of Texas at Dallas, all from the United States; and City University of Hong Kong and Hong Kong Polytechnic University. Two KAIST professors, Chung Chin-Wan and Kim Myoung-Ho, were among the top ten most published scholars. Chung"s papers were mostly about his researches in database, web, and multimedia, while Kim"s researches concerned database systems and distributed information processing. The Journal of Systems and Software, a computer science journal specializing in the software systems, is published by Elsevier, the Dutch-based world"s largest publisher of medical and scientific literature.
2008.02.28
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KAIST Holds Symposium on Metabolic Engineering
The KAIST Institute for Bio-Century held a symposium on metabolic engineering at the auditorium of the KAIST"s Applied Engineering Bldg. on Thursday, Feb. 14, in cooperation with the BK21 Chemical Engineering Research Team. The symposium focused on researches on bio-refinery program and bio-energy production in connection with steep hikes in oil prices and worsening environmental problems, including global warming. Seven Korean experts presented their views on metabolic engineering strategies to effectively produce bio-energy and biofuel and the latest research trends. Among the speakers, Prof. Lee Sang-yup, co-head of the KAIST Institute for Bio-Century, spoke on the theme of "Metabolic Engineering for Bio-refinery and Bio-energy. The symposium provided an opportunity to take a glimpse into the latest research trends of metabolic engineering technology. Metabolic engineering technology is crucial to producing chemicals, energy and other substances from renewable biomass materials in a departure from heavy reliance on crude oil.
2008.02.14
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Prof. Lee Listed on Marquis Who's Who
Professor Lee Ji-hyun of the Graduate School of Culture Technology at KAIST was registered to Marquis Who"s Who, known as one of the world"s three leading biographical dictionaries. Prof. Lee"s biography was published in the 25th anniversary edition of "Marquis Who"s Who in the World 2008." Lee"s research interests are the color and culture, computer-supported collaborative design, creative design, evolutionary systems in design, formal models of design process, representation and reasoning in design and visualization for design information. Lee has published about 30 papers in science journals and for scholastic conferences. She is also a participating professor at KAIST Institute for Entertainment Engineering. Before joining KAIST in 2007, she was an assistant professor at the Department of Digital Media Design and Graduate School of Computational Design, the National Yunlin University of Science & Technology (NYUST) in Taiwan starting from 2002. She received her Ph.D. from the School of Architecture (Computational Design) at Carnegie Mellon University in 2002. She graduated from the Department of Housing & Interior Design at Yonsei University in Seoul in 1991 and received her M.S. from the same university in 1993.
2008.02.14
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KAIST, Hynix Agree to Cooperate in Fostering Skilled Manpower
KAIST and Hynix Semiconductor, the world’s second largest producer of dynamic random access memory (DRAM) chips, have agreed to promote bilateral cooperation in fostering highly skilled manpower for the semiconductor industry. A signing ceremony was held on Jan. 21 in Seoul. The agreement marked an expansion of the scope of cooperation between the two organizations into the system IC industry. Since 1995, KAIST and Hynix have cooperated in fostering human resource specialized in the memory semiconductor area, bringing up a total of 250 highly skilled personnel in the area so far. Under the new agreement, Hynix will provide financial support, including scholarships, to KAIST for the next five years. The number of students subject to the Hynix-financed program will be increased to 20 a year from the current 10. New material engineering and physics will be added to the areas covered by the cooperation program.
2008.01.29
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Int'l Herald Tribune Carries Feature Story on KAIST
International Herald Tribune carried a feature story on KAIST"s ongoing reform efforts on the front page of its Jan. 19-20 edition. The following is the full text of the report. http://www.iht.com/articles/2008/01/18/asia/school.php South Korean science prepares to take on the world By Choe Sang-Hun Friday, January 18, 2008 DAEJEON, South Korea: In Professor Cho Dong Ho"s laboratory at Kaist, South Korea"s top science and technology university, researchers are trying to develop technology that could let you fold a notebook-size electronic display and carry it in your pocket like a handkerchief. It"s too early to say when something like this might be commercially available. But the experiment has already achieved one important breakthrough: it has mobilized professors from eight departments to collaborate on an idea proposed by a student. This arrangement is almost unheard of in South Korea, where the norm is for a senior professor to dictate research projects to his own cloistered team. But it"s only one change afoot at this government-financed university, which has ambitions to transform the culture of South Korean science, and more. "When we first got the student"s idea on what a future display should look like, we thought it was crazy, stuff from science fiction," said Cho, director of Kaist"s Institute for Information Technology Convergence. "But under our new president, we are being urged to try things no one else is likely to." That university president is Suh Nam Pyo, 71, a mechanical engineer who used to be an administrator at the Massachusetts Institute of Technology and who is spearheading closely watched changes that are expected to have ramifications far beyond this campus 90 minutes by car south of Seoul. His moves so far, from requiring professors to teach in English to basing student admissions on factors other than test scores, are aimed at making the university, and by extension South Korean society, much more competitive on a world scale. When the South Korean government hired Suh in 2006 to shake up the state-financed Korean Advanced Institute of Science and Technology (which formally changed its name to its acronym, Kaist, on Jan. 1) the country"s leading schools faced a crisis. The old system, which guaranteed free tuition to lure promising students into science and technology, the drivers of South Korea"s industrial growth, was no longer working as well as it used to. Prosperity was allowing those young people to choose fields of study once viewed as luxuries, like literature and history. Worse, increasing numbers were choosing to study abroad, mostly in the United States, and then not returning home. The fear was that South Korean institutions and enterprises would be gutted of expertise. That concern was voiced at a news conference Monday by the president-elect, Lee Myung Bak, who said the educational system "isn"t producing talent that can compete globally." Kaist, which was established in 1971 with foreign aid, has a special place in South Korean education. The military strongman Park Chung Hee recruited the brightest young people to train there as scientists and engineers. Villagers put up a large banner to celebrate whenever a local child was admitted. "When I was a student here in the mid-1980s, some students stopped before the national flag at the library in the morning and observed a moment of silence, vowing to dedicate ourselves to the nation"s industrial development," said Cho Byung Jin, a professor of electrical engineering. Since his arrival, Suh has become the most talked-about campus reformer in South Korea by taking on some of Kaist"s most hallowed traditions. In a first for a Korean university, Suh has insisted that all classes eventually be taught in English, starting with those aimed at freshmen. "I want Kaist students to work all over the world," Suh said last week. "I don"t want them to be like other Koreans who attend international conferences and have a lunch among themselves because they are afraid of speaking in English." The move to English supports another of his changes: opening undergraduate degree programs to talented non-Koreans. Last year Kaist filled 51 of its 700 admission slots with foreign students on full scholarships. Meanwhile, he has ended free tuition for all; any student whose grade average falls below a B must pay up to $16,000 a year. "My dream is to make Kaist a globalized university, one of the best universities in the world," he said. In what may have been his most daring move, the university denied tenure to 15 of the 35 professors who applied last September. Until then, few if any applicants had failed tenure review in the university"s 36-year history. In this education-obsessed country, Suh"s actions have been watched intensely for their broader impact. More than 82 percent of all high school graduates go on to higher education. What university a South Korean attends in his 20s can determine his position and salary in his 50s, a factor behind recent expos?of prominent South Koreans who faked prestigious diplomas. The system is widely deplored but seldom challenged. From kindergarten, a child"s life is shaped largely by a single goal: doing well in examinations, particularly the all-important national college entrance exam. High school students plod through rote learning from dawn to dusk. Tutoring by "exam doctors" is a multibillion-dollar industry. During vacations, students attend private cram schools, which numbered 33,000 in 2006. One result is a disciplined and conformist work force, an advantage when South Korea rapidly industrialized by copying technology from others. But now, with the country trying to climb the innovation ladder, the rigid school system is proving a stumbling block. The nation"s highly hierarchical ways are often cited to explain how Hwang Woo Suk, the disgraced South Korean scientist who claimed he had produced stems cells from a cloned human embryo, could fabricate research findings with the complicity of junior associates. The ambitious head overseas. Last year, 62,392 South Korean students were enrolled in U.S. colleges and universities, making them the third-largest foreign student group, after Indians (83,833) and Chinese (67,723), according to the U.S. Institute of International Education. Some start earlier. About 35,000 South Korean children below college age go abroad each year, most to the United States to learn English. Against this backdrop, Kaist has been experimenting with test-free admissions. For this year"s class, it brought applicants in for interviews and debates and make presentations while professors looked for creativity and leadership. "About 20 percent of the students who formerly would have won admission didn"t make it under our new guidelines," Suh said. "We are looking for rough diamonds." Challenging the status quo can be risky. The Science and Technology Ministry, which oversees Kaist, had first looked outside South Korea for someone to lead the changes, choosing the Nobel physics laureate Robert Laughlin, who became the first foreigner to head a South Korean university in 2004. But he returned to Stanford University within two years, after the faculty rebelled against him for attempting some of the same changes Suh has instituted, accusing him, among other things, of insensitivity to Korean ways. Suh"s Korean roots and experience shield him from such charges. He did not emigrate to the United States until he was 18 and has worked at Korean universities as well as serving as assistant director at the U.S. National Science Foundation in the 1980s and head of MIT"s department of mechanical engineering from 1991 to 2001. "Reform entails sacrifices, but even if we don"t reform, there will be sacrifices," Suh said. "The difference is that if we don"t reform and don"t encourage competition, it"s the best people who are sacrificed." So far, Suh"s innovations have mostly received favorable reviews. Education Minister Kim Shi Il called them a "very desirable way of making Korea"s universities more competitive globally." The newspaper JoongAng Daily (which publishes an English-language version in partnership with the IHT) praised him for "smashing the iron rice bowls" (ending guaranteed job security) for professors and said, "We must learn from Kaist." Ewan Stewart, a British physicist who has taught at Kaist since 1999, said, "Many of the things President Suh is saying were things I felt should have been said a long time ago." Chung Joo Yeon, a first-year student, said she accepted the need for classes in English, but complained that some professors had no experience teaching in the language. But Cho, the electrical engineering professor, said: "It"s no longer a matter of choice. If we want to maintain our school"s standards, we must draw talents from countries around the world, and that means we must conduct our classes in English." Meanwhile, Lee has promised that as president he will give universities more autonomy by taking the "government"s hands off" how they select their students.
2008.01.23
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Professor Jie-Oh Lee of the Department of Chemistry of KAIST
Professor Jie-Oh Lee of the Department of Chemistry of KAIST was selected as the "KAIST Man of the Year." Lee was cited for his successful identifying of the three-dimensional structure of protein that causes sepsis. His research is expected to contribute greatly to the development of medicines for immune system treatment. The prize was given by KAIST President Suh Nam Pyo at the New Year"s ceremony on Jan. 2, 2008 at the KAIST auditorium. Professor Lee published a series of research papers in Science, one of the world"s most prestigious scientific journals. Most recently, Lee was awarded the "Scientist of the Year" prize by the Korean Science Reporters Association.
2008.01.02
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2008 New Year's Message from President
New Year’s Greeting I would like to wish you and your family a prosperous and happy New Year. I also hope that 2008 will be a great year for KAIST. 2007: Year in Review Thanks to all of your hard work and dedication, 2007 has been a productive year for KAIST. We have undertaken many difficult and challenging tasks in order to make KAIST one of the leading universities in the world. As president, I would like to express my deep appreciation to all members of our community for your many contributions. You have all worked effectively and with great dedication toward accomplishing many of our goals. With your help, leadership, and support we have taken three major steps towards raising our standards. We have improved undergraduate education, created KAIST Institutes to undertake important interdisciplinary research, and improved our system of governance. I believe that these changes will make KAIST much stronger, increasing the intellectual productivity and performance of our students and faculty. But our job is not done yet. We have far to go before reaching our goal of making KAIST one of the best universities in the world. Goals of KAIST KAIST is a great university. Its students are among the brightest young people in the world. We have a first-rate faculty. We have hard working staff, and KAIST benefits from the generous support of the Korean people. It is clear we have what it takes to be one of the leading universities in the world. The history of science and technology teaches us that academia continually creates new intellectual fields to deal with emerging opportunities and to respond to societal needs. Universities that are most successful are those that are best at responding to our changing world. KAIST has the opportunity to become a leading university by searching for and solving important problems that require new approaches and new thinking. There are many reasons KAIST should strive to be the best. Doing so will enable the university to attract the best students and resources, in an increasingly competitive and global academic environment. This will create an atmosphere of intellectual excitement and vigor benefiting both faculty and students. This environment will put our faculty and students in league with the world’s other leading universities’ experts. Tasks Ahead To this end, we still face formidable obstacles. However, we can overcome them through great resolve, ingenuity, planning, and sacrifice. Without change, KAIST will of course continue to advance. But the world’s other leading universities are advancing exponentially faster. KAIST must do more to be in the same league. We must identify new opportunities in all areas, invest in innovative ideas, and lead the field in important areas of science and technology. What we have done in 2007 We have already made progress towards these goals in 2007. Some of our efforts have been difficult and painful to implement. a. Undergraduate education We introduced many measures to educate our students in a way that will prepare them to become future leaders. We have taken measures to make students more accountable for their actions, while also teaching them to be bi-modally functional in synthesis and analysis. We have also pursued international collaborations by establishing dual degree programs, which will begin in 2008 with Carnegie Mellon and Georgia Institute of Technology. We are currently working to establish similar programs with European and Asian universities as well. b. KAIST Institutes We have established research institutes to focus on KAIST’s current strengths. And we have also instituted “high risk/ high return” research-support programs to encourage creativity and innovation. c. EEWS In order to address the most pressing concerns of the 21st century, we have begun major research support in areas related to energy, the environment, water and sustainability. These global problems require international collaboration, which we are actively seeking. d. Governance We restructured KAIST into a department-centric system to enable those who know their fields best to be the primary decision makers. Departments will have the primary responsibility for personnel, finance, space, and education, all of which will be coordinated by the central administration for consistency and checks and balances. We will further develop this system, establishing deep roots in the years to come. e. Buildings and Generous Donors We were extremely fortunate to find generous donors who were willing to provide the financial support for KAIST. I am personally very grateful to Dr. & Mr. Byiung Joon Park for the KI building, and Dr. & Mrs. Neil Papparlardo for the hospital and medical center. We are hoping to find other generous donors for the Sports Complex and other important undertakings of KAIST. Tasks for 2008 In 2008, we must do the following: 1. Teach well. 2. Generate outstanding graduates who can function and compete in a global environment. 3. Produce outstanding research results by identifying important and challenging problems that require creative thinking, new ideas, and innovative paradigms to replace those that do not work any more. 4. Lead the field of science and engineering by anticipating future needs and opportunities. 5. Secure financial resources to compensate outstanding faculty and staff at a globally competitive scale and to maintain an infrastructure fit for research. 6. Increase the size of the faculty and student body to a more competitive level. 7. Recruit outstanding students, faculty and staff. 8. Build new facilities such as the Park Building for KAIST Institutes, the Pappalardo Hospital and Medical Center, the International House, and the Sports Complex. To achieve these tasks, we have created the Five-Year Development Plan and have implemented new programs and policies with the support of the faculty, the students and the staff. New Opportunities Ahead We may have new opportunities to make major contributions in a number of different areas. Before implementing any new programs and policies, the faculty, staff, and administration must consider them carefully and evaluate them thoroughly. I will discuss a few these opportunities that we should consider exploring: 1. Information Technology (IT) The fact that IT is an important area does not need any elaboration. Korea is a leading IT nation. IT has changed the way people communicate, live and produce. It has increased the productivity of the world. IT will continue to evolve and let us do things that cannot be done today. How will the field of IT change in the future? How should KAIST lead the change? Much of the IT revolution consists of hard technologies such as advances in semiconductors, wireless communications, fiber optics, displays, communications technology (switching, networking, etc.), and others. Although these hard technologies will continue to be important and occupy the minds of our brightest engineers, they may evolve in the way the computer field has evolved. For example, in the past, the limited and costly storage of data occupied much of the thinking in the computer science and engineering field. Also the speed of microprocessors was a major limiting factor in the use of computers. However, today the cost of data storage is almost insignificant in comparison to other costs. Advances in data storage have changed the practice and opportunities in the field of computers. Similarly, the current limiting factors involving hardware and data transmission may cease to drive the IT field in the future. What may be equally important is the management and engineering of content that are generated optically, by software, and by the users in a network. Examples of possible new directions in IT (in addition to traditional IT): (a) KAIST should explore whether or not we need to create a new curriculum and a department for “content creation, management and engineering” and generate new kinds of graduates. (b) Another topic that may be considered as being a part of the IT content management issue is the healthcare and management. In this field, Professors WonJoon Kim (BEP), BumSoon Park and SoYoung Kim (Culture Science), and Taesik Lee (Industrial Engineering) are exploring how to deal with health-related issues which will require a new use of IT as well as other disciplines such as design and social science 2. Ocean Systems Engineering and Science KAIST does not currently teach or conduct research on topics related to ocean, shipbuilding, and sea transportation systems, despite their importance in the 21st century. Two-thirds of the earth is covered by water. It is the arbitrator of earth’s climate and holds abundant natural resources. It also provides the cheapest means of transporting goods. It may be the place to sequestrate excess materials such as CO2 that needs to be removed from the atmosphere and land. Furthermore, current shipping systems and harbor design may be outdated and inefficient. Yet research and education in ocean science and engineering are not responding to the current needs of society. Shipbuilding is a very important industry to Korea. Korea builds more ships than any other nation, and ship-building contributes the most to the nation’s current account balance. Further, it appears that the demand for ships will continue to increase as the global shipment of goods and natural resources by ships continues to increase with the rapid industrialization of China and India. With increases in international trade, the need to use the ocean transportation system is likely to grow and exceed the current capacity of the infrastructure. KAIST should explore opportunities in areas related to shipbuilding, natural resource mining, sequestration of CO2 and deposition of other materials, ocean transportation systems, and environmental science and engineering of the ocean. 3. Life Science and Engineering KAIST has made and will be making a major investment in biology, brain science, bioengineering, the ME/PhD program, and other life science and engineering fields. KAIST will be seeking a major funding for research in brain science and neuroscience from abroad as well as within Korea. We need to identify new opportunities to increase the productivity of these diverse investments. Right now, the collaboration and coordination between colleagues in the life sciences and engineering is not well organized, although the KI for the BioCentury is promoting multi-disciplinary research. There has to be a better integration from life science to life engineering and technology at KAIST if we are to convince funding agencies and foundations to give us major financial support and to attract outstanding scholars in this field to KAIST. Concluding Remarks In 2007, we worked hard to make KAIST one of the world’s top universities. We are moving in the right direction in enhancing our students’ long-term personal and professional growth, for advancement of science and engineering, for technological innovation, and for the future well being of humanity. In 2008, we will continue to face new challenges that may appear to be beyond our capabilities, but we know we can achieve a lot when we work together. There are many things we have to do. We must continue to be creative in teaching and research, and we must use our resources wisely and frugally. We must support those amongst us, who are exceptionally creative and hard working, and continue to secure the necessary financial support to strengthen our educational and research programs. Thank you again for your many important contributions. I wish you and your family a most happy and prosperous New Year. January 1, 2008 KAIST President Nam Pyo Suh
2007.12.31
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Professor Jie-Oh Lee awarded 'Scientist of the Year'
Professor Jie-Oh Lee of the Department of Chemistry was awarded the ‘Scientist of the Year’ prize for identifying the three-dimensional structure of protein that causes sepsis, and it was announced by the Korean Science Reporters Association (KOSRA) on November 26th.“Humans have about 30,000 different kinds of proteins, and they all have different structures, just like our faces,” said Professor Lee. “It is extremely helpful to know the three-dimensional shape of proteins when you are trying to understand what their functions in an organism are and trying to develop medicine for them.” When looking for the three-dimensional structure, protein must first be crystallized and radiated with x-ray, so that reflected x-ray can be interpreted. The three-dimensional structure of sepsis immunity proteins TLR1-TLR2 and TLR4-MD2 could not be found until now because they would not even crystallize. “I began to doubt if it was even possible to crystallize them because we went through so many failures,” reflected Professor Lee. In August of last year, after about three years of research, the team finally came up with a new idea. The team decided to ‘stick’ the sepsis immunity protein to protein that easily crystallizes. If the combined structure of sepsis immunity protein and the known protein could be identified, the structure of sepsis immunity protein would be a combined structure subtracted by the known structure. The three-dimensional structure was obtained with x-ray radiation from combined protein crystal. The combined protein was derived from an insect cell with altered DNA. “This method seems very simple but no one ever tried it or no one ever succeeded in it,” said Professor Lee. The result was a horseshoe shaped protein structure. The research team also expects the new protein-combining technology to contribute to the development of a new immune system treatment medicine. The prize-awarding ceremony was held on November 26th in an event hosted by the Korean Hospital Association. Also, Professor Ryong Ryoo of the Department of Chemistry was selected as the National Scientist last month.By KAIST Herald on November, 2007
2007.12.21
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