Engineering
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Success in differentiating Functional Vascular Progenitor Cells (VPC)
KAIST’s Professor Han Yong Man successfully differentiated vascular progenitor cells from human embryonic stem cells and reversed differentiated stem cells.
The research went beyond the current method of synthesis of embryonic body or mice cell ball culture and used the careful alteration of signal transmission system of the human embryonic stem cells to differentiate the formation of vascular progenitor cells.
The team controlled the MEK/ERK and BMP signal transmission system that serves an important role in the self replication of human embryonic stem cells and successfully differentiated 20% of the cells experimented on to vascular progenitor cells.
The vascular progenitor cells produced with such a method successfully differentiated into cells forming the endodermis of the blood vessel, vascular smooth muscle cells and hematopoietic cells in an environment outside of the human body and also successfully differentiated into blood vessels in nude mice.
In addition, the vascular progenitor cell derived from human embryonic cells successfully formed blood vessels or secreted vascular growth factors and increased the blood flow and the necrosis of blood vessels when injected into an animal with limb ischemic illness.
The research was funded by the Ministry of Education, Science and Technology, 21st Century Frontier Research and Development Institution’s Cell Application Research Department and Professor Ko Kyu Young (KAIST), Professor Choi Chul Hee (KAIST), Professor Jeong Hyung Min (Cha Medical School) and Doctor Jo Lee Sook (Researcher in Korea Bio Engineering Institute) participated in it.
The results of the research was published as the cover paper of the September edition of “Blood (IF:10.55)”, the American Blood Journal and has been patented domestically and has finished registration of foreign PCT.
The results of the experiment opened the possibility of providing a patient specific cure using stem cells in the field of blood vessel illness.
2011.01.18 View 12391 -
Professor Kang Suk Joong receives 'Korea Engineering Award.'
KAIST”s Professor Kang Suk Joong of the Department of Material Science and Engineering received ‘Korea Engineering Award’ from the Ministry of Education, Science and Technology and Korea Research Foundation. The award is given to those professors who have accomplished world class research and results.
Professor Kang has potentially redirected the direction of research in the field of the microstructure of materials by explaining the fundamental principle behind how the microstructure of a material that affects the physical properties of the polycrystalline structure and changes through processing. Professor Kang applied the results of his findings in the manufacture of new materials and made significant contributions to Korean Material Engineering Industry and was consequently awarded the award.
The ‘Korea Engineering Award’ was thought of in 1994 and a total of 24 recipients were recognized through the award in various fields like electronics, mechanics, chemistry, construction, etc. The recipient is awarded in addition the President’s award and 50million won as prize money.
The ceremony for ‘Korea Engineering Award’ and the ‘Young Scientist Award’ was held in Seoul Press Center Press Club on the 22nd of December at 3pm. The Minister of Education, Science and Technology (Lee Joo Ho), member of Board of Directors of the Korea Research Foundation (Kim Byoung Gook), Director of Korea Science and Technology Archive (Jeong Gil Seng), along with the recipients attended the ceremony.
In addition, Professor Kang was appointed as Distinguished Professor in March 2010 in recognition of his research accomplishments.
2011.01.18 View 10557 -
Explanation for the polymerized nucleic acid enzyme's abnormal activation found
KAIST’s Professor Park Hyun Kyu of the Department of Bio Chemical Engineering revealed on the 23rd of December 2010 that his team had successfully developed the technology that uses the metal ions to control the abnormal activation of nucleic acids’ enzymes and using this, created a logic gate, which is a core technology in the field of future bio electrons.
The polymerized nucleic acid enzyme works to increase the synthesis of DNA and kicks into action only when the target DNA and primers form complimentary pairs (A and T, C and G).
Professor Park broke the common conception and found that it is possible for none complimentary pairs like T-T and C-C to initiate the activation of the enzyme and thus increase the nucleic acid production, given that there are certain metal ions present.
What Professor Park realized is that the enzymes mistake the uncomplimentary T-T and C-C pairs (with stabilized structures due to the bonding with mercury and silver ions) as being complimentary base pairs. Professor Park described this phenomenon as the “illusionary polymerase activity.”
The research team developed a logic gate based on the “illusionary polymerase activity’ phenomenon.” The logic gate paves the way to the development of future bio electron needed for bio computers and high performance memories.
Professor Park commented, “The research is an advancement of the previous research carried on about metal ions and nucleic acid synthesis. Our research is the first attempt at merging the concepts of the two previously separately carried out researches and can be adapted for testing presence of metal ions and development of a new single nucleotide polymorphic gene analysis technology.”
Professor Park added that, “Our research is a great stride in the field of nano scale electron element research as the results made possible the formation of accurate logic gates through relatively cost efficient and simple system designs.”
On a side note, the research was funded by Korea Research Foundation (Chairman: Park Chan Mo) and was selected as the cover paper for the December issue of ‘Angewandte Chemie International Edition’.
2011.01.18 View 9977 -
Professor Young-Ho Cho elected as head of international academic conference
KAIST’s Professor Young-Ho Cho of the Department of Bio and Brain Engineering was appointed as the head of the PowerMems (Power Micro Electro Mechanical Systems) symposium to be held at Se-Jong Hotel in Seoul from November 15-18, 2011.
Professor Jo is America’s first engineering doctor in the field of MEMS and is the founding member of the BSAC (Berkeley Sensor and Actuator Center), the start of the MEMS technology.
PowerMEMS is the core of green growth and next generation energy production. It focuses on harvesting energy from minute vibrations or renewable energy sources such as sunlight or plants to harvest and store energy via micro or even nano size systems.
The symposium was first held in 2000, and it is where leading experts in the field share papers on the production and harvesting energy in the micro scale.
2011.01.14 View 10374 -
Rise of the mimic-bots that act like we do: Human-machine teamwork.
An online magazine, Technology Marketing Corporation, based in the UK published an article, dated January 8, 2011, on a robot research project led by Professor Jong-Hwan Kim from the Electrical Engineering Department. The article follows below:
Technology Marketing Corporation
[January 08, 2011]
Rise of the mimic-bots that act like we do Human-machine teamwork
(New Scientist Via Acquire Media NewsEdge) Rise of the mimic-bots that act like we doA robot inspired by human mirror neurons can interpret human gestures to learn how it should actNow follow meA robot inspired by human mirror neurons can interpret human gestures to learn how it should actA HUMAN and a robot face each other across the room. The human picks up a ball, tosses it towards the robot, and then pushes a toy car in the same direction.
Confused by two objects coming towards it at the same time, the robot flashes a question mark on a screen. Without speaking, the human makes a throwing gesture. The robot turns its attention to the ball and decides to throw it back.
In this case the robot"s actions were represented by software commands, but it will be only a small step to adapt the system to enable a real robot to infer a human"s wishes from their gestures.
Developed by Ji-Hyeong Han and Jong-Hwan Kim at the Korea Advanced Institute of Science and Technology (KAIST) in Daejeon, the system is designed to respond to the actions of the person confronting it in the same way that our own brains do. The human brain contains specialised cells, called mirror neurons, that appear to fire in the same way when we watch an action being performed by others as they do when we perform the action ourselves. It is thought that this helps us to recognise or predict their intentions.
To perform the same feat, the robot observes what the person is doing, breaks the action down into a simple verbal description, and stores it in its memory. It compares the action it observes with a database of its own actions, and generates a simulation based on the closest match.
The robot also builds up a set of intentions or goals associated with an action. For example, a throwing gesture indicates that the human wants the robot to throw something back. The robot then connects the action "throw" with the object "ball" and adds this to its store of knowledge.
When the memory bank contains two possible intentions that fit the available information, the robot considers them both and determines which results in the most positive feedback from the human?- a smile or a nod, for example. If the robot is confused by conflicting information, it can request another gesture from the human. It also remembers details of each interaction, allowing it to respond more quickly when it finds itself in a situation it has encountered before.
The system should allow robots to interact more effectively with humans, using the same visual cues we use. "Of course, robots can recognise human intentions by understanding speech, but humans would have to make constant, explicit commands to the robot," says Han. "That would be pretty uncomfortable."Socially intelligent robots that can communicate with us through gesture and expression will need to develop a mental model of the person they are dealing with in order to understand their needs, says Chris Melhuish, director of the Bristol Robotics Laboratory in the UK. Using mirror neurons and humans" unique mimicking ability as an inspiration for building such robots could be quite interesting, he says.
Han now plans to test the system on a robot equipped with visual and other sensors to detect people"s gestures. He presented his work at the Robio conference in Tianjin, China, in December. nAs the population of many countries ages, elderly people may share more of their workload with robotic helpers or colleagues. In an effort to make such interactions as easy as possible, Chris Melhuish and colleagues at the Bristol Robotics Laboratory in the UK are leading a Europe-wide collaboration called Cooperative Human Robotic Interaction Systems that is equipping robots with software that recognises an object they are picking up before they hand it to a person. They also have eye-tracking technology that they use to monitor what humans are paying attention to. The goal is to develop robots that can learn to safely perform shared tasks with people, such as stirring a cake mixture as a human adds milk.
(c) 2011 Reed Business Information - UK. All Rights Reserved.
2011.01.10 View 9720 -
KAIST developed a plastic film board less sensitive to heat.
The research result was made the cover of magazine, Advanced Materials and is accredited to paving the way to commercialize flexible display screens and solar power cells.
Transparent plastic and glass cloths, which have a limited thermal expansion needed for the production of flexible display screens and solar power cells, were developed by Korean researchers.
The research, led by KAIST’s Professor Byoung-Soo Bae, was funded by the Engineering Research Center under the initiative of the Ministry of Education, Science and Technology and the National Research Foundation. The research result was printed as the cover paper of ‘Advanced Materials’ which is the leading magazine in the field of materials science.
Professor Bae’s team developed a hybrid material with the same properties as fiber glass. With the material, they created a transparent, plastic film sheet resistant to heat. Transparent plastic film sheets were used by researchers all over the world to develop devices such as flexible displays or solar power cells that can be fit into various living spaces. However, plastic films are heat sensitive and tend to expand as temperature increases, thereby making it difficult to produce displays or solar power cells.
The new transparent, plastic film screen shows that heat expansion index (13ppm/oC) similar to that of glass fiber (9ppm/oC) due to the presence of glass fibers; its heat resistance allows to be used for displays and solar power cells over 250oC.
Professor Bae’s team succeeded in producing a flexible thin plastic film available for use in LCD or AMOLED screens and thin solar power cells.
Professor Bae commented, “Not only the newly developed plastic film has superior qualities, compared to the old models, but also it is cheap to produce, potentially bringing forward the day when flexible displays and solar panels become commonplace. With the cooperation of various industries, research institutes and universities, we will strive to improve the existing design and develop it further.”
2011.01.05 View 12949 -
Korea should find niche in space race, Korea Herald, December 20, 2010
A proud alumna of KAIST, Dr. Yi So-Yeon, who went to the International Space Station in the outer space for the first time as a Korean in 2009, had an interview with the Korea Herald. In the interview, she talks about her experience in working at the space station and her personal plans for the future as a researcher and astronaut. For the article, please click the link:
http://www.koreaherald.com/lifestyle/Detail.jsp?newsMLId=20101220000999
2010.12.21 View 9687
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The KAIST & GIT team developed a power generation technology using bendable thin film nano-materials.
Figure description: Flexible thin film nanomaterials produce electricity.
Can a heart implanted micro robot operate permanently?
Can cell phones and tiny robots implanted in the heart operate permanently without having their batteries charged?
It might sound like science fiction, but these things seem to be possible in the near future. The team of Prof. Keon Jae Lee (KAIST, Dept. of Materials Science and Engineering) and Prof. Zhong Lin Wang (Georgia Institute of Technology, Dept. of Materials Science and Engineering) has developed new forms of highly efficient, flexible nanogenerator technology using the freely bendable piezoelectric ceramic thin film nano-materials that can convert tiny movements of the human body (such as heart beats and blood flow) into electrical energy.
The piezoelectric effect refers to voltage generation when pressure or bending strength is applied to piezoelectric materials. The ceramics, containing a perovskite structure, have a high piezoelectric efficiency. Until now, it has been very difficult to use these ceramic materials to fabricate flexible electronic systems due to their brittle property.
The research team, however, has succeeded in developing a bio-eco-friendly ceramic thin film nanogenerator that is freely bendable without breakdown.
Nanogenerator technology, a power generating system without wires or batteries, combines nanotechnology with piezoelectrics that can be used not only in personal mobile electronics but also in bio-implantable sensors or as an energy source for micro robots. Energy sources in nature (wind, vibration, and sound) and biomechanical forces produced by the human body (heart beats, blood flow, and muscle contraction/relaxation) can infinitely produce nonpolluting energy. (Nanogenerator produces electricity by external forces: http://www.youtube.com/watch?v=tvj0SsBqpBw)
Prof. Keon Jae Lee (KAIST) was involved in the first co-invention of “High Performance Flexible Single Crystal Electronics” during his PhD course at the University of Illinois at Urbana-Champaign. This nanogenerator technology, based on the previous invention, utilized the similar protocol of transferring ceramic thin film nano-materials on flexible substrates and produced voltage generation between electrodes.
Prof. Zhong Lin Wang (Georgia Tech, inventor of the nanogenerator) said, “This technology can be used to turn on an LED by slightly modifying circuits and operate touchable flexible displays. In addition, thin film nano-materials (‘barium titanate’) of this research have the property of both high efficiency and lead-free bio compatibility, which can be used in future medical applications.” This result is published in November online issue of ‘Nano Letters’ ACS journal.
<Video>
Youtube link: http://www.youtube.com/watch?v=tvj0SsBqpBw
Thin Film Nanogenerator produces electricity by external forces.
2010.11.23 View 13947 -
Professor Bae of Industrial Design Wins Good Design Award.
Professor Bae Sang Min’s research team of the Industrial Design Department received a G-Mark on the Product Design Section from the Good Design Awards 2010 organized by the Japan Industrial Design Promotion Organization through the exhibition of a Green Sharing Project, Heartea.
Heartea is a tumbler that allows the user to easily know the temperature of the liquid contained inside. Heartea is a name that combines Heart and Tea to refer to a tumbler that contains heart-warming tea.
Heartea was designed and produced by Professor Bae’s research team and was funded by GS Caltex. World Vision selected charity targets and oversaw distribution, and all of the sales income (about 200 million won) was donated as a scholarship to teenagers with financial difficulties.
The project has begun in 2006, and its accumulative sales are 1.7 billion won. Twenty million won is donated to 147 teenagers every year as scholarship, and through annual sharing camp, social leaders mentor teenagers to help them achieve their dreams.
The Good Design Award organized annually by Japan Industrial Design Promotion Organization has a fifty year tradition and is one of the world’s top four design contests with 6,000 submissions from 50 different countries participated.
Professor Bae’s team has won three of the top four design contests including the German Red Dot Product Award and the American IDEA Product Award.
Along with Heartea, both of foldable MP3 in 2008 and natural humidifier Lovepot in 2009 won an award from these four contests.
“Through continuous research, I hope to create the world’s best philanthropy design research center to help Third World countries and the neglected. I want to participate in creating a better world through design,” said Professor Bae.
2010.11.05 View 11140 -
Minister of Higher Education of Saudi Arabia Visited KAIST to Sign Agreement on Joint Research Projects
Khaled bin Mohammad Al-Anqari, the Minister of Higher Education of Saudi Arabia, visited KAIST on October 26th to conclude a joint agreement with KAIST.
The group of Saudi Arabian visitors included Abdullah bin Abdularhman Al-Othman, President of the King Saud University, Osama bin Sadiq Tayeb, President of King Abdulaziz University, and Khalid bin Salih Al-Sultan, President of the best Saudi Arabian technological university, King Fahad University of Petroleum and Minerals.
Through research agreement between KAIST and the King Saud University and King Fahad University of Petroleum and Minerals, joint research projects, mutual visitations of research professors, interchange of academic programs, joint seminars and scientific societies will be held to promote the lively interchange between higher education institutions of Korea and Saudi Arabia.
In particular, King Saud University and KAIST has signed an agreement on joint research projects in the fields of “Solar-Ocean Thermal Exchange Desalination,” “Develop New Energy Management Service for Residential and Commercial Customers Using Smart Metering and Sensor Network Information” and “Superior Production of Lactic Acid from Saudi Dates Using Bioprocess Technology.”
The projects will be funded by the Saudi Arabian government, and their scope will be determined in the future
“Compared to the robust industrial economic interactions between the Middle East and Korea, the interchange of the two countries’ higher education institutions has been poor,” said Jong Hyun Kim, Visiting Professor of Nuclear & Quantum Engineering Department of KAIST who will be conducting one of the joint programs with the Electrical Engineering Department of the King Saud University. “Like this joint research, I hope KAIST will, in many different ways, lead the way in cooperating and interacting with higher education institutions of the Middle EAST.”
Al-Anquari, Minister of Higher Education of Saudi Arabia, who showed great interest in KAIST’s innovative research and high technology development, expressed his will to put more effort into extending the interchange between universities of Saudi Arabia and of Korea, including KAIST.
2010.11.03 View 14128 -
Nanowerk Spotlight: Bacteria as environmentally friendly nanoparticle factories, Sep. 24, 2010
The Nanowerk.com is a leading portal site for nanotechnology and nanosciences, which runs a daily news section called “Spotlight.” On September 24, 2010, the Spotlight published an article on the latest developments of the research by a KAIST team headed by Distinguished Professor Sang-Yup Lee of the Chemical and Bimolecular Engineering Department. For the article, please click the link below:
Nanowerk Spotlight: Bacteria as environmentally friendly nanoparticle factories, Sep. 24, 2010
By Michael Berger.
http://www.nanowerk.com/spotlight/spotid=18188.php
2010.09.25 View 9992
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KAIST was invited to the World Economic Forum's fourth "Summer Davos."
KAIST attended the World Economic Forum’s “Summer Davos Forum” held from September 13 to 15 in Tianjin, China. The Summer Davos Forum hosted various sessions and meetings with international dignitaries from governments, business and public organizations, and academia on the main theme of “Driving Growth through Sustainability.”
On September 14, four subjects including “Electric Vehicles,” “Humanoid Robotics,” “Next Generation of Biomaterials,” and “New Developments in Neuroengineering” were presented by KAIST, followed by discussions with forum participants.
Professor Jae-Seung Jeong of the Bio and Brain Engineering Department, Sang-Yup Lee of the Chemical and Biomolecular Engineering Department, Joon-Ho Oh of the Mechanical Engineering Department, and President Nam-Pyo Suh participated in the forum as presenters of the topic. Of these speakers, Professors Jae-Seung Jeong and Sang-Yup Lee were nominated by the World Economic Forum (WEF) as members of the “Young Global Leader” and “Global Agenda Council on Emerging Technologies,” respectively.
President Suh was also invited to the CEO Insight Group and delivered an opening speech on OLEV (Online Electric Vehicle) and the Mobile Harbor. President Suh plans to sign an MOU for research cooperation with Jong-Hoo Kim of Bell Lab and Shirley Jackson of the Rensselaer Polytechnic Institute in the near future, respectively.
Since 2007, the WEF, in charge of the world’s largest international conference called “Davos Forum” has hosted a “Summer Davos Forum,” also called as the “Annual Meeting of New Champions.” The Summer Davos Forum consists of nations, rising global companies, next generation of global leaders, and cities or nations that lead technological innovations. Unlike the annual Davos Forum held in January, the “Annual Meeting of New Champions” is held in September of each year in Tianjin and Dalian, China.
Since 2009, the WEF has added a special session called IdeasLab in the Davos and Summer Davos Forums. Through IdeasLab, prominent universities from all over the world, research organizations, venture businesses, NGOs, and NPOs are invited to exchange and discuss innovative and creative ideas that can contribute to the development of mankind. Until now, universities including INSEAD, EPFL-ETH, MIT, Oxford, Yale, Harvard, Rensselaer Polytechnic Institute, Tsinghua University, and Keio University have been invited to the IdeasLab. KAIST is the first Korean university to attend this session.
2010.09.17 View 17538