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New Diagnosis System for Cardiovascular Disease Developed
Professor Park Hyun Kyu of the department of Biological-Chemical Engineering developed a new diagnosis system for diagnosing cardiovascular diseases using E.coli to test the homocysteine concentration in the blood. The research team used the genetic recombination process to produce two different biologically illuminant nutrition cultures and compared the growth rate of the homocysteine between the two cultures by comparing the degree of luminescence. The technology can allow the simultaneous analysis of blood samples en masse and is also economical and thus is being regarded as a major step forward in the field of homocysteine concentration analysis which is a rapidly growing field. The conventional method used high performance liquid chromatography which took a long time to complete and was costly to run. The advantage of the newly developed system is that it gets rid of costly steps as it only needs to grow E.coli and measure the luminescence of the naturally occurring illuminant. The research was published as the cover paper of the April edition of ‘Analytical Chemistry’.
2011.05.11
View 7932
Low Cost and Simple Gene Analysis Technology Developed
Professor Park Hyun Kyu of the Department of Biology and Chemical Engineering has developed a ‘real time CPR’ using Methylene Blue (nucleic acid bonding molecule with Electro-Chemical property). The current gene analysis being used in the field is the real time PCR (Polymerase Chain Reaction) which takes advantage of the luminescent property of the gene and therefore requires expensive machines and chemicals to run. By contrast, the electro-chemical method is easy to use and low cost and, most importantly, it allows the machine to become small and portable. Professor Park’s research team used the decrease in the electro-chemical signal when the Methylene Blue reacts with nucleic acid and applied this to PCR which allowed for the real time analysis of the nucleic acid amplification process. With the result of the experiment as the basis, the team was able to perform a trial with Chlamydia trachomatis, a pathogen that causes sexually transmitted disease. The result showed that the electro-chemical method showed the same performance level as the real time PCR, which proved that the technology can be applied to diagnosing various diseases and gene research.
2011.04.30
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Professor Min Beom Ki develops metamaterial with high index of refraction
Korean research team was able to theoretically prove that a metamaterial with high index of refraction does exist and produced it experimentally. Professor Min Beom Ki, Dr. Choi Moo Han, and Doctorate candidate Lee Seung Hoon was joined by Dr. Kang Kwang Yong’s team from ETRI, KAIST’s Professor Less Yong Hee’s team, and Seoul National University’s Professor Park Nam Kyu’s team. The research was funded by the Basic Research Support Program initiated by the Ministry of Education, Science, and Technology and Korea Research Federation. The result of the research was published in ‘Nature’ magazine and is one of the few researches carried out by teams composed entirely of Koreans. Metamaterials are materials that have physical properties beyond those materials’ properties that are found in nature. It is formed not with atoms, but with synthetic atoms which have smaller structures than wavelengths. The optical and electromagnetic waves’ properties of metamaterials can be altered significantly which has caught the attention of scientists worldwide. Professor Min Beom Ki’s team independently designed and created a dielectric metamaterial with high polarization and low diamagnetism with an index of refraction of 38.6, highest synthesized index value. It is expected that the result of the experiment will help develop high resolution imaging system and ultra small, hyper sensitive optical devices.
2011.02.23
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Class of 2011 Undergraduate Freshmen Matriculation Ceremony Held
The 2011 Undergraduate Freshmen Matriculation Ceremony took place on the 10th of February with 950 freshmen and 1000 parents. Freshmen representative Park Min Jae (19 years old, Korea Science High School for the Gifted), and Jeong Hyun Lee (18 years old, Gyoung Gi Science High School) gave the Freshmen oath followed by President Suh Nam Pyo’s address. After the ceremony that KAIST choir club ‘CHORUS’ gave a welcoming performance and the Q and A session with the parents of the students involved Lee Kyu Min dean of school affairs, Yoo Hui Joon dean of administration, and Lee Seung Sup dean of student affairs. KAIST has decreased winter vacation by a month and commences the new semester in February and increased summer vacation to three months from two months since 2009 to encourage students to experience society.
2011.02.21
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Explanation for the polymerized nucleic acid enzyme's abnormal activation found
KAIST’s Professor Park Hyun Kyu of the Department of Bio Chemical Engineering revealed on the 23rd of December 2010 that his team had successfully developed the technology that uses the metal ions to control the abnormal activation of nucleic acids’ enzymes and using this, created a logic gate, which is a core technology in the field of future bio electrons. The polymerized nucleic acid enzyme works to increase the synthesis of DNA and kicks into action only when the target DNA and primers form complimentary pairs (A and T, C and G). Professor Park broke the common conception and found that it is possible for none complimentary pairs like T-T and C-C to initiate the activation of the enzyme and thus increase the nucleic acid production, given that there are certain metal ions present. What Professor Park realized is that the enzymes mistake the uncomplimentary T-T and C-C pairs (with stabilized structures due to the bonding with mercury and silver ions) as being complimentary base pairs. Professor Park described this phenomenon as the “illusionary polymerase activity.” The research team developed a logic gate based on the “illusionary polymerase activity’ phenomenon.” The logic gate paves the way to the development of future bio electron needed for bio computers and high performance memories. Professor Park commented, “The research is an advancement of the previous research carried on about metal ions and nucleic acid synthesis. Our research is the first attempt at merging the concepts of the two previously separately carried out researches and can be adapted for testing presence of metal ions and development of a new single nucleotide polymorphic gene analysis technology.” Professor Park added that, “Our research is a great stride in the field of nano scale electron element research as the results made possible the formation of accurate logic gates through relatively cost efficient and simple system designs.” On a side note, the research was funded by Korea Research Foundation (Chairman: Park Chan Mo) and was selected as the cover paper for the December issue of ‘Angewandte Chemie International Edition’.
2011.01.18
View 9644
OLEV Safety Confirmed by International Standards
On September 19, KAIST announced that the electromagnetic (EM) field levels of its online electric vehicle (OLEV) measured in June and September of this year demonstrated verification of its safety. Last June, the EM field level of OLEV installed at the Seoul Grand Park was measured by the Korea Research Institute of Standards and Science (KRISS) to test its harmfulness to human. The results were 0.5 ~ 61mG which is within the national and international standards of 62.5mG. KRISS measured EM field levels on 22 spots on the side of and at the center of OLEV at a fixed distance (30cm) but variable heights (5cm~150cm) according to the national standard of measurement methods for electromagnetic fields of household appliances and similar apparatuses with regard to human exposure (IEC 62233). In addition, another testing took place on September 13 following a request by National Assemblywoman Young-Ah Park, a member of the National Assembly’s Education, Science and Technology Committee, who has raised an issue on the safety of OLEV. This testing session was held by EMF Safety, Inc., an institution designated by Park, and it tested the EM field level of the same OLEV train that was tested in June. As a result, the September measurements were well within the national and international standards with 0~24.1mG. The test was conducted under the presence of third party to produce a fair and objective result. As reference, the EM field level results are well within the American IEEE electromagnetic field standards of 1,100 mG. The September measurements were produced by Park’s recommendation of following the criteria specified in the measurement procedures of IEC 62110, “Electric and magnetic field levels generated by AC power systems to public exposure,” which were 15 measurements at a fixed 20cm distance at the side of and from the center of OLEV with variable heights of 50cm~150cm.
2010.09.27
View 11018
The 8th International Conference on Metabolic Engineering was held on June 13-18, 2010 in Jeju Island, South Korea.
From left to right, top row: Distinguished Professor and the conference chair Sang Yup Lee, Sang-Hyup Kim - Secretary to the President of Korea, Dr. Jay Keasling, Dr. Greg Stephanopoulos. Left to right, bottom row: Dr. William Provine, Dr. Terry Papoutsakis, Dr, Jens Nielsen, Dr. Lars Nielsen. The importance of industrial biotechnology that produces chemicals and materials from renewable biomass is increasing due to climate change and the dearth of natural resources. Industrial biotechnology refers to a technology that allows sustainable bio-based production of chemicals and materials that could enrich human"s lives using microorganisms. This is where metabolic engineering comes into play for successful application of microorganisms, in which they are engineered in our intended way for improved production capability. The 8th International Conference on Metabolic Engineering, the longest running conference of its kind, was held on June 13-18, 2010 at the International Convention Center in Jeju Island, South Korea. Distinguished Professor Sang Yup Lee of KAIST, Dean of College of Life Science and Bioengineering and Co-Director of Institute for the BioCentury, chaired the conference with the main theme of "metabolic engineering for green growth." With 300 delegates selected by the committee, papers on production of biofuels, chemicals, biopolymers, and pharmaceutics and the development of fundamental metabolic engineering techniques were presented at the conference along with examples of successful commercialization of products developed by several global companies. Sang Hyup Kim, Secretary to the President of Korea, gave an opening plenary lecture entitled "Korean green growth initiative," to inform experts from around the globe of the leadership on green growth in Korea. Young Hoon Park, President of Korea Research Institute of Bioscience and Biotechnology (KRIBB, Korea) delivered his congratulatory address. Sang Hyup Kim said, "Hosting an international conference in Korea on metabolic engineering, which forms a core technology necessary for the development of environmentally friendly processes for producing chemicals and biofuels from renewable biomass, is very meaningful as green growth is a big issue around the globe. This is a great chance to show the excellence of Korea"s green growth associated technology to experts in metabolic engineering and industrial biotechnology." A total of 47 invited lectures in this conference included recent and important topics, for instance, "Synthetic biology for synthetic fuels" by Dr. Jay Keasling from the Joint BioEnergy Institute (USA), "Microbial oil production from renewable feedstocks" by Dr. Greg Stephanopoulos from MIT (USA), "Yeast as a platform cell factory for production of fuels and chemicals" by Dr. Jens Nielsen from Chalmers University (Sweden), "Mammalian synthetic biology - from tools to therapies" by Dr. Martin Fussengger from ETH (Switzerland), "Building, modeling, and applications of metabolic and transcriptional regulatory networks at a genome-scale" by Dr. Bernhard Palsson from the University of California - San Diego (USA), "Genome analysis and engineering Eschericha coli for sucrose utilization" by Dr. Lars Nielsen from the University of Queensland (Australia), "Artificial microorganisms by synthetic biology" by Dr. Daniel Gibson from JCVI (USA), and "Metabolomics and its applications" by Dr. Masaru Tomita from Keio University (Japan). From Korea, Dr. Jin Hwan Park from the research group of Dr. Sang Yup Lee at KAIST presented "Systems metabolic engineering of Escherichia coli for amino acid production," and Dr. Ji Hyun Kim from KRIBB presented "Genome sequencing and omics systems analysis of the protein cell factory of Escherichia coli". Global companies involved in biorefinery presented their recent research outcomes with emphasis on commercialized technologies. They included "Metabolic and process engineering for commercial outcomes" by Dr. William Provine from DuPont (USA), "Direct production of 1,4-butanediol from renewable feedstocks" by Dr. Mark Burk from Genomatica (USA), "Development of an economically sustainable bioprocess for the production of bio 1,2-propanediol" by Dr. Francis Voelker from Metabolic Explorer (France), "Biotechnology to the bottom-line: low pH lactic acid production at industrial scale" by Dr. Pirkko Suominen from Cargill (USA), "Bioisoprene™: traditional monomer, traditional chemistry, sustainable source" by Dr. Gregg Whited from Danisco (USA) and "Efficient production of pharmaceuticals by engineered fungi" by Dr. Roel Bovenberg from DSM (Netherlands). This biennial conference also presented the International Metabolic Engineering Award (expanded version of the previous Merck Metabolic Engineering Award) to the best metabolic engineer in the world. The 2010 International Metabolic Engineering Award went to Dr. E. Terry Papoutsakis from the University of Delaware (USA) who has contributed to the production of biobutanol through the metabolic engineering of Clostridia in the last three decades, and he gave an award lecture. Dr. Sang Yup Lee, the current chair of the upcoming conference, was the previous recipient of this award at the last metabolic engineering conference in 2008. In addition to the invited lectures, a total of 156 carefully selected poster papers were chosen for presentation, and awards were presented to the best posters after rigorous review by the committee members. Such awards included "The 2010 Metabolic Engineering Best Poster Award" and the "2010 Young Metabolic Engineer Award" from the Metabolic Engineering conference, and prestigious international journal awards, including "Wiley Biotechnology Journal Best Poster Award", "Wiley Biotechnology and Bioengineering Best Poster Award" and "Elsevier Metabolic Engineering Best Paper Award." Dr. Catherine Goodman, a senior editor of Nature Chemical Biology, also presented the "Nature Chemical Biology Best Poster Award on Metabolic Engineering." Regarding this conference, Dr. Sang Yup Lee, the conference chair, said, "This conference is the best international conference in the field of metabolic engineering, which is held every two years, and Korea is the first Asian country to host it. All the experts and students spend time together from early breakfast to late poster sessions, which is a distinct feature of this conference. Although the number of delegates had typically been limited to 200, around 300 delegates were selected this year to accept more attendees from many people who have been interested in metabolic engineering. Also, it is very fitting that "green growth" is the main topic of this conference because Korea is playing a key role in this field. I"m grateful to the Lotte Scholarship Foundation, COFCO, GS Caltex, Bioneer, US DOE, US NSF, Daesang, CJ Cheiljedang, Genomatica and DuPont who provided us with generous financial support that allowed the successful organization of this conference." The conference was organized by the Systems Biology Research Project Team supported by the Ministry of Eduction, Science and Technology (MEST), Microbial Frontier Research Project Group, World Class University Project Group at KAIST, Institute for the BioCentury at KAIST, Korean Society for Biotechnology and Bioengineering, and the Engineering Conference International (ECI) of the United States. Inquiries: Professor Sang Yup Lee (+82-42-350-3930), industrialbio@gmail.com
2010.06.25
View 17006
KAIST held an opening ceremony for the completion of KAIST Institute Building.
A Korean American businessman and his wife, Byiung Jun Park and Chunghi Hong, donated 10 million USD for the construction of the building. KAIST hosted an opening ceremony on May 11, 2010 for the new addition to its campus, called the Chunghi & Byiung Jun (BJ) Park KAIST Institute Building. The KI Building will serve as a hub for creative multidisciplinary researches. A Korean American businessman and his wife made a considerable contribution for the construction of the building, worth 10 million USD. KAIST called the building Byiung Jun (BJ) Park and Chunghi Hong in recognition of their contribution. Chairman Park was the founder of the Merchandise Testing Laboratory, a leading textile quality control multinational. It took 19 months to finish the construction of the KI Building with a total cost of 36 billion Korean won. The building consists of one basement and five ground floors. At the basement, there are clean room and equipment storage room; on the 2nd and 3rd floors, conference and exhibition halls; and on the rest of the floors, research labs and administration offices are to be located. KAIST’s eight integral research institutes will be placed inside the building: the BioCentury; Information Technology Convergence; Design of Complex Systems; Entertainment Engineering; the NanoCentury; Eco-Energy; Urban Space and Systems; and Optical Science and Technology. Approximately 230 professors from 25 departments of various academic fields will make the KI Building home for study and research. The KI Building will play a great role in producing world-class convergence research works by KAIST researchers and professors, thereby making a contribution to the improvement of national competitiveness. Vice President of KI Building, Sang-Soo Kim, said, “There has been no such place for us to concentrate research manpower and equipment scattered around the campus. By having all the necessary resources at one place will allow us to conduct convergence researches more efficiently and effectively. I’d like to express my appreciation for the Ministry of Education and Science and Technology as well as Chairman Byiung Jun (BJ) Park, who gave us tremendous supports in the process of constructing the KI Building.” “The building’s inside has a unique office structure, getting rid of walls or partitions between institutes or departments, to stimulate an environment conducive to convergence researches. We hope to present a new model for creative multidisciplinary researches through a selective and focused approach to be facilitated by institutes at the KI Building,” added by the vice president.
2010.05.20
View 11332
KAIST's Industrial Design Program Rated among World's Best
KAIST"s master"s program in the area of industrial design has been rated among the world"s best in the latest survey of the World"s Best Design Programs published in the Oct. 2, 2009 issue of BusinessWeek, university authorities said Wednesday, Oct. 7. The magazine has selected 30 top design programs at the postgraduate level from all over the world. Only six programs in Asia -- one each in Korea, Japan, China, Hong Kong, Taiwan and India -- were included in the list, while famous design schools in the United States and Europe dominated the list. Why was KAIST on the list? The magazine commented: "The master"s program, set up in 1991, focuses on human-centered design, technology convergence, and business innovation. Students take courses in design marketing and design management to understand wider corporate issues and also learn how to use design as a strategic tool." In presenting the list of top design programs, the magazine said that "students in these programs take classes in art, management and science, for example, and create projects in multi-disciplinary teams with students from other schools, They aim to use design for strategy rather than merely for aesthetics and may find jobs as design managers, researchers or business consultants." The magazine concluded that "these programs have formally established hybrid curricula." Meanwhile, Woo-sung Park, a KAIST graduate, has been chosen among the "Twenty-one People Who Will Change Business" surveyed by the magazine. After graduating with a B.S. in industrial design from KAIST in 2005, Park worked for a design firm for two years. He then returned to KAIST to develop the analytical skills he now uses at the global consultancy Boston Consulting Group in Seoul.
2009.10.09
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Transparent Antenna for Automobile Developed
A research team led by Prof. Jae-Woo Park of the School of Electrical Engineering & Computer Science, KAIST, developed a transparent antenna for the next-generation automobiles, university authorities said on Monday (Aug. 17). The development was made possible through joint researches with the Hyundai-Kia Automotive Group; Winncom, a car antenna manufacturer; and a group of researchers led by Han-Ki Kim of the Department of Display Materials Engineering at Kyung Hee University in Seoul. The transparent antennas were developed in two kinds -- one for the HSDPA (High-Speed Downlink Packet Access), a new protocol for mobile telephone data transmission, and the other for transmitting and receiving radio wave for emergency call. Using the transparent electrically conductive film formation technology, the transparent antennas are to be mounted on the windshield of a vehicle. "The development of transparent antenna represents a step forward for the advancement of the next-generation automotive electronic technology," said Seong-woo Kim, a senior researcher at the Hyundai-Kia Group.
2009.08.18
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Prof. Park to Receive HP's Annual Innovation Research Award
Prof. In-Kyu Park of the Department of Mechanical Engineering, KAIST, has been will receive an award from Hewlett-Packard"s second annual Labs Innovation Research Program, university authorities said on Wednesday (July 8). Prof. Park was chosen as the winner of the research award for his paper entitled "Eco-friendly nanomanufacturing for intelligent environment sensing applications." Sixty projects from 46 universities in 12 countries were selected as the recipients of the awards from HP Labs, the company"s central research arm. The program is designed to create opportunities for colleges, universities and research institutes to conduct collaborative research with HP. HP Labs Innovation Research Awards provide project funding of up to $100,000 for one year to each of the chosen academic institutions, which is renewable for up to three years based on research progress and HP business requirements. Prof. Park has conducted joint researches on nanoimprinting, nanosensors, and nanoelectronics with HP"s Information and Quantum Systems Lab since 2005. Starting from the later half of 2009, he is to receive research grants under the industry-academia cooperation program of the world"s information technology giant firm.
2009.07.09
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Dr. Lyu Opens Oriental Health Clinic for KAIST Students on Campus
Dr. Keun-Chul Lyu, an Oriental medical scientist who donated property valued at 57.8 billion won (US$56 million) to KAIST last year, opened a health clinic and a medical research center for astronauts on the KAIST campus on Monday (April 13). The opening of the two facilities represent the scientist"s lifelong wish to serve society by giving back his knowledge, experience and assets. Monday"s opening ceremony was attended by 100-odd well-wishers including KAIST President Nam-Pyo Suh, Daejeon City Mayor Sung-Hyo Park and Ki-Ok Kim, President of the Korea Institute of Oriental Medicine. Dr. Lyu"s Health Clinic which is equipped with eight units of medical treatment apparatus called "health booster" that Dr. Lyu developed will offer free medical care for KAIST students. "I would like to open the clinic as a space where students can receive medical treatment and rest anytime," Dr. Lyu said. The research center for astronauts will focus on the researches to take care of health of space fliers and to help lessen the impact astronauts suffer when the spacecraft enters into the earth´s atmosphere. On the same day, Dr. Lyu donated his lifetime collection of about 500 rare relic items such as Buddhist statues, ink stones and incense burners to KAIST.
2009.04.15
View 10033
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