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Nature Biotechnology Nominates Sang Yup Lee of KAIST for Top 20 Translational Researchers of 2014
Nature Biotechnology, recognized as the most prestigious journal in the field of biotechnology, has released today its list of the Top 20 Translational Researchers of 2014. Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST (Korea Advanced Institute of Science and Technology) ranked seventh in the list. He is the only Asian researcher listed.
The journal, in partnership with IP Checkups, a patent analytics firm, presents an annual ranking of researchers based on their paper and patent output. The list includes, among others, each researcher’s most-cited patent in the past five years and their H index, a measurement to evaluate the impact of a researcher’s published work utilizing citation analysis. (More details can be found at http://www.nature.com/bioent/2015/150801/full/bioe.2015.9.html.)
American institutions made up the majority of the list, with 18 universities and research institutes, and the remainder was filled by KAIST in Korea and the Commonwealth Scientific and Industrial Research Organization (CSIRO) in Australia.
Globally known as a leading researcher in systems metabolic engineering, Professor Lee has published more than 500 journal papers and 580 patents. He has received many awards, including the Citation Classic Award, Elmer Gaden Award, Merck Metabolic Engineering Award, ACS Marvin Johnson Award, SIMB Charles Thom Award, POSCO TJ Park Prize, Amgen Biochemical Engineering Award, and the Ho Am Prize in Engineering.
2015.08.27 View 8860 -
KAIST holds the 2015 KAIST-MIT-Technion International Symposium on Nano Science
The 2015 KAIST-MIT-Technion International Symposium on Nano Science was held on August 11, 2015 at the KAIST campus. The event took place under three subtopics: Materials for Production and Storage of Renewable Energy, Functional Materials, and Multiferroic Materials.
The joint symposium invited more than 300 experts in material science and engineering including ten speakers and panelists. From MIT (Massachusetts Institute of Technology), Professors Harry L. Tuller and Geoffrey S. Beach in the Department of Material Engineering, as well as Professor Gregory Rutledge in the Department of Chemical Engineering joined the symposium. Professor Avner Rothschild in the Department of Material Engineering and Professor Yair Ein-Eli in the Department of Chemical Engineering at Technion Institute of Technology in Israel also participated.
From KAIST, Professors Il-Doo Kim, Byong-Guk Park, and Yeon-Sik Jung in the Department of Materials Science and Engineering, Professor Chan-Ho Yang in the Department of Physics, and Professor Doh-Chang Lee in the Department of Chemical and Biomolecular Engineering spoke at the event. The list of topics included “Next Generation Lithium-Air Battery,” “Nano Materials for High Performance Energy Storage System,” and “Iron Oxide Nanoparticles Photoelectrode for the Conversion and Storage of Solar Energy.”
In its efforts to promote cooperation among the three universities, KAIST plans to send six students to MIT and one student to Technion for joint research.
Professor Il-Doo Kim, who organized the symposium said, “We believe this kind of international gathering will serve as an opportunity for scholars from leading universities to share their expertise in material science and help them better understand on the recent trends in nanoscience and its related technology.”
2015.08.12 View 7311 -
'Engineered Bacterium Produces 1,3-Diaminopropane'
A research team led by Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at KAIST reported, for the first time, the production of 1,3-diaminopropane via fermentation of an engineered bacterium.
1,3-Diaminopropane is a three carbon diamine, which has a wide range of industrial applications including epoxy resin and cross-linking agents, as well as precursors for pharmaceuticals, agrochemicals, and organic chemicals. It can also be polymerized with dicarboxylic acids to make polyamides (nylons) for use as engineering plastics, medical materials, and adhesives.
Traditionally, 1,3-diaminopropane is derived from petroleum-based processes. In effort to address critical problems such as the depletion of petroleum and environmental issues inherent to the petroleum-based processes, the research team has developed an Escherichia coli (E. coli) strain capable of producing 1,3-diaminopropane. Using this technology, 1,3-diaminopropane can now be produced from renewable biomass instead of petroleum.
E. coli as found in nature is unable to produce 1,3-diaminopropane. Metabolic engineering, a technology to transform microorganisms into highly efficient microbial cell factories capable of producing chemical compounds of interest, was utilized to engineer the E. coli strain. First, naturally existing metabolic pathways for the biosynthesis of 1,3-diaminopropane were introduced into a virtual cell in silico to determine the most efficient metabolic pathway for the 1,3-diaminopropane production. The metabolic pathway selected was then introduced into an E. coli strain and successfully produced 1,3-diaminopropane for the first time in the world.
The research team applied metabolic engineering additionally, and the production titer of 1,3-diaminopropane increased about 21 fold. The Fed-batch fermentation of the engineered E. coli strain produced 13 grams per liter of 1,3-diaminoproapne. With this technology, 1,3-diaminopropane can be produced using renewable biomass, and it will be the starting point for replacing the current petroleum-based processes with bio-based processes.
Professor Lee said, “Our study suggested a possibility to produce 1,3-diaminopropane based on biorefinery. Further study will be done to increase the titer and productivity of 1,3-diaminopropane.”
This work was published online in Scientific Reports on August 11, 2015.
Reference: Chae, T.U. et al. "Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine," Scientific Reports:
http://www.nature.com/articles/srep13040
This research was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries from Ministry of Science, ICT and Future Planning (MSIP) through the National Research Foundation (NRF) of Korea.
Figure 1: Metabolic engineering strategies for 1,3-diaminopropane production using C4 pathway
Figure 2: Fed-batch fermentation profiles of two final engineered E. coli strains
2015.08.12 View 10125 -
Professor Sang-Min Bae Receives the 2015 Red Dot Design Award
Professor Sang-Min Bae and his research team from the Industrial Design Department of KAIST have received three awards from the 2015 Red Dot Design Award: the Best of the Best Award and two Design Concept Awards.
Being one of the most prestigious international design awards, the Red Dot Design Award serves to identify good design concept and innovation that will be the precursors of tomorrow’s great product. Its annual award ceremony will take place on September 25, 2015, at the Red Dot Design Museum in Singapore.
This year, the Award received 4,680 entries from 61 countries, and only the top 5.7% of them was able to garner the awards. In addition to two Red Dot Design Concept Awards, Professor Bae’s team won the Best of the Best Award, coming through a four hundred to one competition.
Awarded the Best of the Best Award, Boxchool is a modular classroom built on shipping containers whose aim is to give underprivileged children equal opportunities for learning. Jointly designed with an IT corporation in Korea, SK Telecom, the container is also a smart classroom.
Boxchool received the Best of the Best Award in recognition of its contribution to giving an equal learning opportunity to needy children, as well as its environmental characteristics.
The research team strengthened the mobility of the container and creatively addressed problems associated with using containers as classrooms such as insulation and inadequate space in environments which hamper teaching. The modular classroom can function in any setting since it can generate electricity from installed solar panels. The rainwater utilization system allows autonomous operation of the classroom.
The team earned the Red Dot Design Concept Award for a self-generating interactive tent, which was jointly designed with Kolon Sport, a Korean outdoor products company, as an industry-university cooperation project. The interactive tent differs from conventional tents by adding features that allow users to engage with the environment. For example, the installed organic solar cells allowed users to have prolonged outdoor activities by supplying electricity generated therefrom. Users can also enjoy greater ventilation. This permits the tent to be utilized as a temporary residence in the third world.
Another recipient of the Red Dot Design Concept Award, Snow Energy is a portable self-generating lamp and charger, which contains a thermo-element, generating electricity from temperature difference. Electricity is generated by pouring hot water inside a tank and cold water into a neighboring space. Snow Energy, which is sustainable and eco-friendly, will be especially helpful during outdoor activities when there is no electricity available.
Professor Bae's research team, ID+IM, has endeavored to address inequality and philanthropy through two projects, the Nanum (a Korean word to mean “sharing”) and the Seed Projects. Since 2005, they have received internationally recognized awards more than 40 times.
Picture 1: Recipient of the Best of the Best Award of the 2015 Red Dot Design Award, Boxchool is a modular classroom built on shipping containers
Picture 2: Recipient of the 2015 Red Dot Design Concept Award, the self-generating interactive tent
Picture 3: Recipient of the 2015 Red Dot Design Concept Award, Snow Energy is a portable self-generating lamp and charger which generates electricity from the temperature difference
2015.08.05 View 10443 -
Dr. Se-Jung Kim Receives the Grand Prize at the International Photo and Image Contest on Light
Dr. Se-Jung Kim of the Physics Department at KAIST received the Grand Prize at the 2015 Photo and Image Contest of the International Year of Light and Light-based Technologies.
The United Nations has designated the year 2015 as the International Year of Light and Light-based Technologies.
The Optical Society of Korea celebrated the UN’s designation by hosting an international photo and image contest on the theme of light and optics related technology.
Dr. Kim presented a photo of images taken from a liquid crystal, which was entitled “A Micro Pinwheel.” She took pictures of liquid crystal images with a polarizing microscope and then colored the pictures. The liquid crystal has self-assembled circle domain structures, and each domain can form vortex optics. Her adviser for the project is Professor Yong-Hoon Cho of the Physics Department.
Her work was exhibited during the annual conference of the Optical Society of Korea, which was held on July 13-15, 2015 at Gyeong-Ju Hwabaek International Convention Center. It will also be exhibited at the National Science Museum in Gwacheon and the Kim Dae-Jung Convention Center in Gwangju.
Picture: A Micro Pinwheel
2015.07.31 View 8572 -
A Technology Holding Company Establishes Two Companies Based on Technologies Developed at KAIST
Mirae Holdings is a technology holding company created by four science and technology universities, KAIST, DIGIST (Daegu Gyeongbuk Institute of Science and Technology), GIST (Gwangju Institute of Science and Technology), and UNIST (Ulsan National Institute of Science and Technology) in 2014 to commercialize the universities’ research achievements. The company identifies promising technologies for commercialization, makes business plans, establishes venture capitals, and invests in startup companies.
Over the past year, Mirae Holdings has established two venture companies based on the technologies developed at KAIST. In September 2014, it founded Cresem Inc., a company used the anisotropic conductive film (ACF) bonding technology, which was developed by Professor Kyung-Wook Paik of the Material Science and Engineering Department at KAIST. Cresem provides a technology to bond electronic parts ultrasonically. The company is expected to have 860,000 USD worth of sales within the first year of its launching.
Last June, Mirae Holdings created another company, Doctor Kitchen, with the technology developed by Professor Gwan-Su Yi of the Bio and Brain Engineering Department at KAIST. Doctor Kitchen supplies precooked food, which helps diabetic patients regulate their diet. The company offers a personalized diet plan to customers so that they can effectively manage their disease and monitor their blood sugar level efficiently.
The Chief Executive Officer of Mirae Holdings, Young-Ho Kim, said, “We can assist KAIST researchers who aspire to create a company based on their research outcomes through various stages of startup services such as making business plans, securing venture capitals, and networking with existing businesses.”
Young-Ho Kim (left in the picture), the Chief Executive Officer of Mirae Holdings, holds a certificate of company registration with Sang-Min Oh (right in the picture), the Chief Executive Officer of Cresem.
Young-Ho Kim (left in the picture), the Chief Executive Officer of Mirae Holdings, holds a certificate of company registration with Jae-Yeun Park (right in the picture), the Chief Executive Officer of Dr. Kitchen.
2015.07.29 View 10943 -
Professor Suk-Joong Kang Receives the Richard Brook and Helmholtz Awards
Professor Suk-Joong Kang of KAIST’s Department of Materials Sciences and Engineering received the Richard Brook Award from the European Ceramic Society at its 14th conference held on June 21, 2015, in Toledo, Spain. The award is presented to the most distinguished academic or engineer in ceramics from a non-European country. Professor Kang gave the commemorative lecture after the award ceremony.
Professor Kang is an expert in the field of sintering and microstructural evolution in ceramics and metals. He suggested a new model for grain growth and identified the principles of microstructural evolution.
He also received the 2015 Helmholtz Fellow Award in June. The Helmholtz Association, the largest scientific organization in Germany, confers the award on outstanding senior scientists based outside Germany who have made great academic and research achievements in their fields.
Professor Kang said of the Brook Award, “It is such an honor to receive an award from an eminent global institution. I take this opportunity to thank my students and colleagues for their support, and I will work harder for my research.”
2015.07.20 View 5744 -
KAIST Undergraduates Organize the Largest Interdisciplinary Conference in Asia
The largest interdisciplinary conference in Asia hosted by KAIST undergraduates for students around the world will be held in KAIST. The organizing committee of International Conference for the Integration of Science, Technology and Society (ICISTS) will hold the ICISTS-KAIST 2015 in KAIST and Hotel ICC from August 3-7, 2015, with around 300 Korean and international participants.
ICISTS-KAIST was established in 2005 to provide an annual platform for students to discuss the integration and the convergence of science, technology and society, regardless of their academic background.
This year’s theme is "Shaping the Future" and the topics for the conference are robotics, medicine, and science communication.
The keynote speakers are Vitalic Buterin, the winner of the World Technology Award in 2014 for the co-creation and invention of Ethereum and Alan Irwin, a well-known scholar of science, technology and society as well as the Dean of Research at the Copenhagen Business School in Denmark.
Other notable speakers include Adam Marcus, a professor of Hematology and Medical Oncology, Emory University School of Medicine; Stefan Lorenz Sorgner, the Director and co-founder of Beyond Humanism Network; Hideto Nakajima, a professor in the Department of History, Philosophy and Social Studies of Science and Technology at Tokyo Institute of Technology; Wendell Wallach, a lecturer at the Yale University Interdisciplinary Center for Bioethics; Jinil Lee, a professor in the Division of Biological Science and Technology at Yonsei University; and Sangwook Kim, an editor of APCTP web journal Crossroads and a professor in the Department of Physics Education, Pusan National University.
Last year, more than 300 students from 50 different countries attended the ICISTS-KAIST 2014 as delegates to exchange their thoughts and ideas on science, technology, and society.
To register for the event, please visit www.icists.org.
2015.07.14 View 7185 -
KAIST Startups Annually Engage 33,000 People, and Their Sales Total Nearly 10 Billion Dollars
According to a recent study, KAIST startups annually engage 33,000 people, and their sales total nearly 10 billion US dollars. Also amongst 1,245 companies, 50 were listed in stock markets including KOSDAQ and KONEX. President Kang of KAIST commissioned an evaluation of KAIST startups last year. The report consisted of six chapters: current status of entrepreneurs and companies, cross analysis based on individuals’ background and academic degree, annual performance analysis, and current status of startup assistance.
The report categorized the startups with respect to the founders’ background. Of 1,245 companies, KAIST alumni founded 929 (74.6%) of the companies under study: 191 (15.3%) were located within the KAIST campuses, 91 (7.3%) were founded by enrolled students, and 74 (2.7%) by professors. The startup founders had different levels of education: 515 (41.4%) founders had master’s degree, 443 (35.6%) Ph.D. degree, and only 213 (17.1%) had only bachelor’s degree as the highest level of education attained. The reason behind the majority of founders having a master’s degree or higher degree is that many people established a startup after obtaining specialized knowledge and skills.
Focusing on the founders’ college majors, 719 (70.6%) founders were from the engineering department, 111 (10.9%) from the business administration department, 103 (10.1%) from the natural science department, and 86 (8.4%) from other departments. Looking at the companies' locations, 462 (37.5%) were placed in Seoul, 355 (28.8%) in Daejeon, and 273 (22.2%) in Gyeonggi.
By the end of 2013, the total asset of 1,069 companies came to 12 billion and 444 million dollars. Their total sales figure was 10 billion and 13 million dollars, and annual employments summed up to 33,000 people. The companies generated a significant portion of gross regional domestic product (GRDP) in each region. They formed 0.49% of GRDP of Seoul, took up 1.67% GRDP of Gyeonggi, and 5.53% of that of Daejeon.
Along with the performance analysis, the report also took a survey of suggestions on future startup assistance and opinions on current startup assistance policies. To a question asking what constituted the most difficult part of startup, 31.7% of respondents answered “attraction of investment,” 22.8% chose “a lack of human resources,” and 16.8% said “consulting” amongst 214 respondents. The study showed that major and medium enterprises face difficulty in finding human resources whereas small businesses experience obstacles attracting investment. Some startups had help from KAIST: 44 startups were provided with the office space, 21 had educational supports, and 18 were supported in research and development.
The report demonstrates that startups established by KAIST alumni and members play a key role in the South Korean economy despite KAIST’s short startup history, which began only since the end of 1990s. Based on this report, KAIST plans to listen continuously to the needs of alumni founders, and use those responses as a guide to entrepreneurship education for current students.
The Dean of the Office of University and Industry Cooperation, Joongmyeon Bae, who oversaw the publication of this report, said, "As this report is the first in Korea to study the status of alumni startups, it will be incredibly valuable in modifying the startup assistance policies.”
To spread an entrepreneurial spirit and start-up cultures in the campus and enhance the startup supporting system, KAIST has founded various startup centers on and off the campus.
2015.07.14 View 7492 -
Dong-Young Lee, a Doctoral Candidate, Receives the Best Paper Award
Dong-Young Lee, a Ph.D. candidate in the Mechanical Engineering Department, KAIST, received the Best Paper Award at the 18th International Conference on Composite Structures (ICCS). The event was held in Lisbon, Portugal, on June 15-18, 2015. Mr. Lee’s adviser is Professor Dai-Gil Lee of the same department.
The ICCS is held every other year, and is one of the largest and long-established conferences on composite materials and structures in the world. At this year’s conference, a total of 680 papers were presented, among which, two papers were chosen for the Best Paper Award, including Mr. Lee’s.
The paper, entitled “Gasket-integrated Carbon and Silicon Elastomer Composite Bipolar Plate for High-temperature PEMFC,” will be published in the September issue of Composite Structures which is one of the top journals in mechanical engineering as judged by the Google Scholar Metrics rankings.
Mr. Lee dropped the conventional method of PEMFC (Proton Exchange Membrane Fuel Cells) assembly and instead developed a gasket-integrated carbon and silicone elastomer composite bipolar plate. This technology significantly increased the energy efficiency of fuel cells and their productivity.
Mr. Lee said, “I would like to thank the many people who supported me, especially my Ph.D. adviser, Professor Dai-Gil Lee. Without their encouragement, I would have not won this award. I hope my research will contribute to solving energy problems in the future.”
In addition, Professor Joon-Woo Im from Chonbuk National University, Senior Researcher Il-Bum Choi from the Agency for Defense Development, and a fellow doctoral candidate Soo-Hyun Nam from KAIST participated in this research project.
2015.07.09 View 8107 -
3D Plasmon Antenna Capable of Focusing Light into Few Nanometers
Professors Myung-Ki Kim and Yong-Hee Lee, both of the Physics Department at KAIST, and their research teams have developed a three dimensional (3D) gap-plasmon antenna which can focus light into a space a few nanometers wide. Their research findings were published in the June 10th issue of Nano Letters.
Focusing light into a point-like space is an active research field with many applications. However, concentrating light into a smaller space than its wavelength is often hindered by diffraction. To tackle this problem, many researchers have utilized the plasmonic phenomenon of a metal where light can be confined to a greater extent by overcoming the diffraction limit.
Many researchers have focused on developing a two dimensional (2D) plasmon antenna and were able to focus a light under 5 nanometers wide. However, this 2D antenna revealed a challenge: the light disperses to the opposite end regardless of how small its beam was focused. To solve this difficulty, a 3D structure had to be employed to maximize the light's intensity.
Adopting the proximal focused-ion-beam milling technology, the KAIST research team developed a 3D four nanometer wide gap-plasmon antenna. By squeezing the photons into a 3D nano space of 4 x 10 x 10 nm3 size, the researchers were able to increase the intensity of light by 400,000 times stronger than that of the incident light. Capitalizing on the enhanced intensity of light within the antenna, they intensified the second-harmonic signal and verified that the light was focused in the nano gap by scanning cathodoluminescent images.
The researchers anticipate that this technology will improve the speed of data transfer and processing up to the level of a terahertz (one trillion times per second) and to enlarge the storage volume per unit area on hard disks by 100 times. In addition, high definition images of submolecule size can be taken with actual light, instead of with an electron microscope, while improving the semiconductor process to a smaller size of few nanometers.
Professor Kim said, “A simple yet ingenious idea has shifted the research paradigm from 2D gap-plasmon antennas to 3D antennas. This technology will see numerous applications including in the field of information technology, data storage, imaging medical science, and semiconductor processes.”
The research was sponsored by the National Research Foundation of Korea.
Figure 1: 3D Gap-Plasmon Antenna Structure and Simulation Results
Figure 2 – Constructed 3D Gap-Plasmon Antenna Structure
Figure 3 – Amplified Second Harmonic Signal Generation and Light Focused in the Nano Gap
2015.06.24 View 9689 -
Professor Kyoungsik Yu Receives the Young IT Engineer Award from IEEE and IEIE of Korea
Professor Kyoungsik Yu of KAIST’s Department of Electrical Engineering is the recipient of this year’s Young IT (Information Technology) Engineer Award that was co-hosted by the Institute of Electrical and Electronics Engineers (IEEE), the Institute of Electronics Engineers of Korea (IEIE), and Haedong Science Culture Foundation in Korea. The award was presented on June 22, 2015 at The Ramada Plaza Jeju Hotel on Jeju Island, Korea.
The Young IT Engineer Award is given to emerging scientists who have made significant contributions to the advancement of technology, society, environment, and creative education.
Professor Yu's main research interests are IT, energy, and imaging through miniaturization and integration of optoelectronic devices. His contribution to academic and technological development is reflected in his publication of more than 100 papers in international journals and conferences, which were cited over 2,200 times.
Professor Yu said, “I’m honored to receive this award and am encouraged by it. I also find the award meaningful because the United Nations has designated this year as the “International Year of Light and Light-based Technologies,” the field I have been involved in as a researcher.”
In addition to Korea, the IEEE has jointly hosted and presented this award to researchers in countries such as Chile, Ecuador, Peru, Singapore, and Italy.
2015.06.22 View 10055