science
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Novel material that prevents health decline with age found
Professor Kim Dae Soo (Department of Biological Science), his research team, the Choong Nam University Medicine School, and various companies conducted collaborative research succeeded in developing a novel material that prevents health decline with age. The result was published in PLoS One Journal with the title “Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice”.
Longevity and health can be obtained with reducing consumption of food and aerobic exercise.
Professor Kim’s team focused on the fact that reduced consumption of food and aerobic exercise increase the coenzyme (NAD+) which suppresses the aging of cells. The research team discovered that by activating NQO1 enzyme with Beta-lapachone, the amount of NAD+ in the body increases even without reduction of food consumption or aerobic exercise.
Even consumption of Beta-lapachone by aging mice caused an improved on the brain and exercise ability of the mice. It is expected that commercialization of Beta-lapachone will be possible as it is a chemical that is commonly found in herbs used in both the orient and the oxidant.
2012.12.21 View 6951 -
The hereditary factor of autism revealed
Korean researchers have successfully investigated the causes and hereditary factors for autistic behavior and proposed a new treatment method with fewer side effects.
This research was jointly supported by the Ministry of Education, Science and Technology and the National Research Foundation as part of the Leading Researcher and Science Research Center Program
The research findings were publishing in the June edition of Nature magazine and will also be introduced in the July edition of Nature Reviews Drug Discovery, under the title ‘Autistic-like social behavior in Shank2-mutant mice improved by restoring NMDA receptor function’.
The research team found that lack of Shank2 genes in mice, which are responsible for the production of synapse proteins, caused autistic-like behavior. The results strongly suggested that the Shank2 gene was linked to autistic behavior and that Shank2 deficiency induced autistic behaviors.
Autism is a neural development disorder characterized by impaired social interaction, repetitive behavior, mental retardation, anxiety and hyperactivity. Around 100 million people worldwide display symptoms of autistic behavior. Recent studies conducted by the University of Washington revealed that 1 out of 3 young adults who display autistic behavior do not fit into the workplace or get accepted to college, a much higher rate than any other disorder. However, an effective cure has not yet been developed and current treatments are limited to reducing repetitive behavior.
The research team confirmed autistic-like social behavior in mice without the Shank2 genes and that the mice had decreased levels of neurotransmission in the NMDA receptor. The mice also showed damaged synaptic plasticity* in the hippocampus**.
* Plasticity: ability of the connectionbetween two neurons to change in strength in response to transmission of information
**Hippocampus: part of the brain responsible for short-term and long-term memory as well as spatial navigation.
The research team also found out that, to restore the function of the NMDA receptor, the passive stimulation of certain receptors, such as the mGLuR5, yielded better treatment results than the direct stimulation of the NMDA. This greatly reduces the side effects associated with the direct stimulation of receptors, resulting in a more effective treatment method.
This research successfully investigated the function of the Shank2 gene in the nerve tissue and showed how the reduced function of the NMDA receptor, due to the lack of the gene, resulted in autistic behavior. It also provided new possibilities for the treatment of autistic behavior and impaired social interaction
2012.06.24 View 10764
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New Era for Measuring Ultra Fast Phenomena: Atto Science Era
Domestic researchers successfully measured the exact status of the rapidly changing Helium atom using an atto second pulse. Thanks to this discovery, many ultrafast phenomena in nature can now be precisely measured. This will lead to an opening of a new "Atto Science" era.
Prof. Nam Chang Hee led this research team and Ph.d Kim Kyung Taek and Prof. Choi Nak Ryul also participated in this research. They have conducted the research under the support of the Researcher Support Program initiated by The Ministry of Education and Science and Korea Research Foundation. The research result was published in the prestigious journal "Physical Review Letters" on March 2nd. (Title: Amplitude and Phase Reconstruction of Electron Wave Packets for Probing Ultrafast Photoionization Dynamics)
Prof. Nam Chang Hee"s research team used atto second pulse to measure the ultrafast photoionization.
His team used atto second X-ray pulse and femto second laser pulse to photoionize Helium atoms, and measure the wave speed of the produced electron to closely investigate the ultrafast photoionization process.
Atom"s photoionization measurement using an atto second pulse was possible using the research team"s high-energy femto second laser and high-performance photo ion measurement device. This research team succeeded in producing the shortest 60 atto second pulse in the world using high-harmonic waves.
The research team used high-power femto second laser to produce atto second high-harmonic pulse from argon gas, used this to photoionize Helium atoms, and measured the ultrafast photoionization of the atoms.
Prof. Nam Chang Hee said, "This research precisely measured the exact status of rapidly changing Helium atoms. I am planning to research on measuring the ultrafast phenomena inside atoms and molecules and controlling the status of the atoms and molecules based on the research result."
2012.04.04 View 9578
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Businessweek: How Twitter Could Unleash World Peace, April 11, 2011
A KAIST graduate scholar, Meeyoung Cha, conducted a joint study with international researchers and released a paper on the aspect of twitter as an emerging cyber arena for political and social debates and discussions. An article on the paper from Businessweek follows:
Businessweek
April 11, 2011, 9:08PM EST text size: TT
How Twitter Could Unleash World Peace
Researchers from Britain, Korea, and Germany have determined that the amount of fresh information you get on Twitter is less a matter of what you follow than whom—and who follows you
By Bobbie Johnson
On certain days, Twitter can feel like the world"s biggest, fastest echo chamber. Since we tend to follow people who are similar to us, we often see our own views reflected back—meaning a gloomy cloud of irritation can rapidly swirl into a cyclone of outrage as we hear from other people who feel as we do. A group of computer scientists have discovered that the opposite may also be true. Can Twitter be part of the solution, not merely part of the problem?
In a study to be presented at a conference in July, a team of researchers from the U.K."s University of Cambridge, Korea"s Graduate School of cultural Technology-KAIST, and Germany"s Max Planck Institute for Software Systems show how Twitter can provide users greater access to more varied political viewpoints and media sources than they might otherwise get.
The paper, called "The Media Landscape in Twitter(http://www.cl.cam.ac.uk/~jac22/out/twitter-diverse.pdf)," explains how the team made surprising discoveries when they looked into the site"s usage patterns. First they looked at who follows whom and discovered that Twitter is a highly politicized space. Then they examined patterns of tweeting and retweeting to try to understand how people receive information on Twitter—and what they might see. Their conclusion: Although Twitter is a pretty partisan space, it can offer unprecedented opportunities to break down the barriers that plague local, national, and international politics.
How? Through retweets and interaction—what the authors call "indirect media exposure." As they put it, this "expands the political diversity of news to which users are exposed to a surprising extent, increasing the range by between 60 percent and 98 percent. These results are valuable because they have not been readily available to traditional media and they can help predict how we will read news and how publishers will interact with us in the future."
If you"re interested in the way Twitter works, I recommend reading the paper, which isn"t very long. Meanwhile, let"s boil it down to a few key pieces of data and see what lessons they can teach.
Most Twitter users are political. Just over half (50.8 percent) of all Twitter users studied showed a distinct political bias in the media outlets and individuals they followed. Most of those lean to the left of the political spectrum, accounting for 62 percent of users who demonstrated some bias. Thirty-seven percent were doggedly centrist. Just 1 percent of Twitter users who showed a political preference were right-wing.
Here are a couple of caveats about reading too much into the sharp divide the authors found. Given that Twitter"s user base is younger and more metropolitan than the societal norm, it"s not surprising that it"s weighted to the left. It"s worth noting that this study was undertaken more than a year ago; since then, Twitter has grown dramatically, while global politics have largely skewed back toward the right. Twitter"s user base today might reflect a more-balanced political picture. Either way, there"s a big split.
Twitter has secondary and tertiary benefits. Most organizations comprehend Twitter in simple terms: More followers means more exposure. But the study shows that it"s not just about those you follow, but those your followers follow—essentially the people in your extended network. The network offers a number of routes for information from fresh sources to get to you. According to the study, some 80 percent of users choose to follow at least 10 media sources, but they are exposed to between 6 and 10 times as many media sources through their friends.
People outweigh brands. Many of the biggest Twitter accounts are big media brands such as CNN (TWX) and Time, but the study suggests that Twitter"s active users tend to prefer individuals over outlets. So while the average follower of @NYTimes (NYT) has six followers apiece, individual journalists have followers who boast a median following count of around 100. That gives individual journalists—who are, the study says, more likely to link to a multiplicity of sources—a much wider, more influential network of connections.
The inference is that the personal touch of a journalist is more important than the lofty, impersonal tone of publications that largely act as promotion channels for their content. It"s a discovery that reminded me of Twitter"s recent blog post on the science of the hashtag, which found that hashtags explode in usage when they are picked up by individuals with the most dedicated—not necessarily the largest—followings.
Active users access a wider range of views. The researchers say that indirect exposure expands political diversity by a "significant amount," despite other studies showing a tendency for social networks to do the opposite. "Other studies have found a stronger tendency of homophily; blogs of different political views rarely linked to each other," they point out. "One possible reason is that a Twitter network encompasses several different relationships—from shared interest, to familial ties, friends, and acquaintances—so political similarity doesn"t necessarily exist in all such ties."
This is not to say that Twitter"s creators should be preparing a Nobel Prize-winning speech. Far from it: The influence of its diversity is unknown. It could be that many people who see messages they disagree with simply change their behavior to screen out such material in future. But it shows that there is a potential to do something positive at Twitter. It"s clear there"s much work to be done. The researchers say they want to investigate a number of areas they"ve uncovered, having provided important insights at a time when politics seem more fractious and divided than ever.
2011.04.12 View 10713
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A KAIST graduate to become a professor at a prestigious university in UAE
A KAIST graduate to become a professor at a prestigious university in UAE
Dr. Jerald Yoo, a KAIST graduate, has been appointed as an assistant professor at the Masdar Institute of Science and Technology (MIST) in Abu Dhabi, United Arab Emirates (UAE), by the recommendation of the Massachusetts Institute of Technology (MIT) since April 1, 2010.
The MIST is a private, not-for-profit, independent, research-driven institute developed with the support and cooperation of MIT and the Abu Dhabi government, which was opened in September 2009. Currently, at the school, there are 25 professors and 100 students from 22 countries around the world. The institute has a campus in Masdar City where the Abu Dhabi government plans to nurture it as a “place for zero carbon emissions.”
According to an agreement between the MIST and MIT, Professor Yoo will teach and work on co-research projects at MIT for one year beginning in May 2010 and then working at the MIST thereafter.
Professor Yoo received all of his degrees (BS, MS, and Ph.D.) from KAIST majoring in electrical engineering and earned his doctoral degree in January 2010. His research works included developing a wearable patch to monitor bio signals with an application of wearable sensor networks and low energy electronic circuit technologies. During his doctoral study, Professor Yoo published papers at the IEEE International Solid-State Circuits Conference (ISSCC) and in journals of IEEE Solid-State Circuits Society (SSCS).
Professor Yoo said, "The wearable health care system is certainly necessary to improve the quality of our lives, and the field should receive a sustaining support for further research. I will do my best to continuously produce valuable research results and hope that my research works will be helpful for an academic exchange between South Korea and Abu Dhabi.”
About the Masdar Institute of Science and Technology (MIST) in Abu Dhabi:
http://www.masdar.ac.ae/
The Masdar Institute is the centerpiece of the Masdar Initiative, a landmark program announced in April 2006 by the government of Abu Dhabi to establish an entirely new economic sector dedicated to alternative and sustainable energy. Masdar is a highly-strategic initiative with primary objectives of: helping drive the economic diversification of Abu Dhabi; maintaining and expanding Abu Dhabi"s position in evolving global energy markets; positioning Abu Dhabi as a developer of technology; and making a meaningful contribution towards sustainable human development.
The Masdar Institute is a private, not-for-profit, independent, research-driven institute developed with the support and cooperation of the Massachusetts Institute of Technology (MIT). The Institute offers Masters and (eventually) PhD programs in science and engineering disciplines, with a focus on advanced energy and sustainable technologies. It welcomes and encourages applications from qualified local and international students and provides fellowships to talented students who meet its high admission standards. Its faculty is of the highest quality and the intent is to have the structure of its top administration similar to MIT"s.
2010.04.13 View 11985 -
Interesting research results were published on the use of Twitter.
The number of “followers” on your Twitter account does not necessarily mean that “Your opinions matter much” to other people.
A KAIST graduate researcher, Mi-Young Cha, joined an interesting project that studies the influence of a popular social media, Twitter. Most of Twitter users today consider the number of followers as a measurement of their influence on the social sphere. According to the research paper, however, this connection does not seem to standing together. For details, please click the link below for an article published by the New York Times.
Dr. Cha received all of her post secondary education degrees in Computer Science, including her Ph.D. in 2008, from KAIST. Since 2008 till now, she has been a post doctoral researcher at Max Planck Institute for Software Systems (MPI-SWS) based in Germany.
[New York Times Article, March 19, 2010]
http://www.nytimes.com/external/readwriteweb/2010/03/19/19readwriteweb-the-million-follower-fallacy-audience-size-d-3203.html
2010.04.05 View 12144
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Prof. Chong Unveils New Human Movement Model
A KAIST research team headed by Prof. Song Chong of the School of Electrical Engineering and Computer Science has developed a new statistical model that simulates human mobility patterns, mimicking the way people move over the course of a day, a month or longer, university sources said on Tuesday (May 12).
The model, developed in collaboration with scientists at North Carolina State University, is the first to represent the regular movement patterns of humans using statistical data.
The model has a variety of potential uses, ranging from land use planning to public health studies on epidemic disease.
The researchers gave global positioning system (GPS) devices to approximately 100 volunteers at five locations in the U.S. and South Korea and tracked the participants" movements over time. By tracing the points where the study participants stopped, and their movement trajectories, researchers were able to determine patterns of mobility behavior.
The researchers were then able to emulate these fundamental statistical properties of human mobility into a model that could be used to represent the regular daily movement of humans. The model, called Self-similar Least Action Walk (SLAW), will have a wide array of practical applications.
The research, "SLAW: A Mobility Model for Human Walks," was presented on April 20 at the 28th IEEE Conference on Computer Communications in Rio de Janeiro, Brazil. The National Science Foundation of the U.S. funded the research.
2009.05.13 View 12808