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Two Undergraduate KAIST Students Publish a Book on Health Management
Joonho Suh of the Aerospace Engineering Department and Jiho Suh of the Mechanical Engineering Department are both brothers and undergraduates at KAIST.
The Suh brothers, who are three years apart, have recently published a self-help book in English on staying healthy entitled “A Scientific Approach to Building Muscle: Mass Effect.”
The book introduces techniques to build muscles, adapting them from an engineering concept called "Active Torque Control (ACT)," the management of turning forces imposed on a vehicle. Just as ACT influences the performance of a vehicle, good exercise involves the right degree of body angles and the right direction of body movements to keep the best posture necessary for burning calories and strengthening muscles.
In the book, they also suggest healthy diet plans based on scientific knowledge and data that the writers borrowed from such fields as anatomy, physiology, and motor mechanics to maintain a healthy weight.
Joonho Suh said,
“If we understand the mechanism of how our body works, the chances are high we will have good muscle tone and a balanced diet. We used a great deal of scientific knowledge and turned it into a health management program that can be customized per individual needs.”
The younger brother, Jiho, added,
“In fact, we applied our methods in the book to beginners who took weight training and fitness for one hour a day for one month, we learned that their muscle mass increased by 1-1.5 kg while losing body fat by 2-3 kg.”
The brothers said they planned to publish a Korean language version of the book next year.
The authors of "Mass Effect": Joonho Suh (left) and Jiho Suh (right)
2015.10.26 View 7150 -
KAIST's Graduate School of Culture Technology Celebrates Its Tenth Anniversary
The Graduate School of Culture Technology (GSCT) at KAIST hosted a ceremony and a variety of events to celebrate its tenth anniversary on October 22, 2015, on campus.
Established in 2005 with the support of the Ministry of Culture, Sports and Tourism of the Republic of Korea, GSCT offers an intensive, in-depth education in culture technology, an interdisciplinary field first introduced in Korea by KAIST, which brings arts, humanities, science, and technology together in an academic and research arena.
Over the years, the graduate school has fostered top-notch researchers and professionals who have played a leading role in the development of a Korean culture contents industry that includes movies, broadcasting programs, music, games, and culture events.
After the anniversary ceremony, GSCT held a "Demo Day" to showcase its major research projects. A total of 41 projects were presented under the themes of “Art and Science,” “Human and Humane,” and “Virtual Reality vs Reality.”
In addition, there was a seminar held on GSTC’s ten-year accomplishment and future planning with the school’s Professors Sunghee Lee, Juyong Park, and Juhan Nam; a cultural event for the public called the “Talk Concert,” which included many professionals in culture industry and academia to share ideas and views; and the Homecoming Day for GSTC graduates. So far, the graduate school has produced 295 masters and 34 doctors. About 34% of its graduates are employed in the movie, game, and broadcasting sectors, 33% in the social networking service and Internet industry, and 33% in performing art and exhibition and event.
Dong-Man Lee, the Dean of KAIST's Graduate School of Culture Technology, said,
“We will continue to develop our school to lead the advancement of the Korean culture industry, contributing to the growth of Korean Wave, the popularity of Korean culture, in the global community.”
In the picture below, Dean Lee delivers a speech to celebrate the school’s tenth anniversary.
Soo-Man Lee, the founding chairman of S.M. Entertainment, speaks at the Talk Concert.
Scenes from the Demo Day
2015.10.26 View 7877 -
Professors Sukbok Chang and Jang-Wook Choi Receive the 2015 Knowledge Award from the Korean Government
The Ministry of Science, ICT and Future Planning (MISP) of the Republic of Korea announced the 2015 Knowledge Awards on October 20, 2015. Two KAIST professors received the award.
Established in 2009, the awards are presented to Korean scientists whose publications have contributed to the international science community. Specifically, the MISP used the two biggest science databases, Science Citation Index Expanded (SCIE) and Scopus, to identify ten highly cited papers ranked in the top 1% by total citations in the past ten years.
Professor Sukbok Chang of Chemistry (left in the picture below) is a global authority in the field of catalytic hydrocarbon functionalization. His paper entitled “Palladium-catalyzed C-H Functionalization of Pyridine N-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes,” which was published in the Journal of the American Chemical Society in 2008, was once selected by Thomson Reuters as one of the “Most Influential Research Papers of the Month.” In 2011, the American Chemical Society included his paper in the list of the top 20 research papers that were most frequently cited in the last three years.
Professor Jang-Wook Choi of the Graduate School of EEWS (Energy, Environment, Water, and Sustainability) has been known for his leading research in rechargeable battery, supercapacitor, and materials chemistry. In particular, his work on secondary fuel cells attracted significant attention from academia and industry in Korea. Professor Choi developed a super-thin flexible lithium-ion battery this year, thinner than a credit card, which lasts longer than the existing batteries and with greater performance. He also developed new electrode materials for next-generation sodium-ion and magnesium secondary fuel cells.
Professor Sukbok Chang (left) and Professor Jang-Wook Choi (right)
2015.10.23 View 10964 -
Establishment of System Metabolic Engineering Strategies
Although conventional petrochemical processes have generated chemicals and materials which have been useful to mankind, they have also triggered a variety of environmental problems including climate change and relied too much on nonrenewable natural resources. To ameliorate this, researchers have actively pursued the development of industrial microbial strains around the globe in order to overproduce industrially useful chemicals and materials from microbes using renewable biomass. This discipline is called metabolic engineering.
Thanks to advances in genetic engineering and our knowledge of cellular metabolism, conventional metabolic engineering efforts have succeeded to a certain extent in developing microbial strains that overproduce bioproducts at an industrial level. However, many metabolic engineering projects launched in academic labs do not reach commercial markets due to a failure to fully integrate industrial bioprocesses.
In response to this, Distinguished Professor Sang Yup Lee and Dr. Hyun Uk Kim, both from the Department of Chemical and Biomolecular Engineering at KAIST, have recently suggested ten general strategies of systems metabolic engineering to successfully develop industrial microbial strains. Systems metabolic engineering differs from conventional metabolic engineering by incorporating traditional metabolic engineering approaches along with tools of other fields, such as systems biology, synthetic biology, and molecular evolution.
The ten strategies of systems metabolic engineering have been featured in Nature Biotechnology released online in October 2015, which is entitled "Systems strategies for developing industrial microbial strains."
The strategies cover economic, state-of-the-art biological techniques and traditional bioprocess aspects. Specifically, they consist of: 1) project design including economic evaluation of a target bioproduct; 2) selection of host strains to be used for overproduction of a bioproduct; 3) metabolic pathway reconstruction for bioproducts that are not naturally produced in the selected host strains; 4) increasing tolerance of a host strain against the bioproduct; 5) removing negative regulatory circuits in the microbial host limiting overproduction of a bioproduct; 6) rerouting intracellular fluxes to optimize cofactor and precursor availability necessary for the bioproduct formation; 7) diagnosing and optimizing metabolic fluxes towards product formation; 8) diagnosis and optimization of microbial culture conditions including carbon sources; 9) system-wide gene manipulation to further increase the host strain's production performance using high-throughput genome-scale engineering and computational tools; and 10) scale-up fermentation of the developed strain and diagnosis for the reproducibility of the strain's production performance.
These ten strategies were articulated with successful examples of the production of L-arginine using Corynebacterium glutamicum, 1,4-butanediol using Escherichia coli, and L-lysine and bio-nylon using C. glutamicum.
Professor Sang Yup Lee said, "At the moment, the chance of commercializing microbial strains developed in academic labs is very low. The strategies of systems metabolic engineering outlined in this analysis can serve as guidelines when developing industrial microbial strains. We hope that these strategies contribute to improving opportunities to commercialize microbial strains developed in academic labs with drastically reduced costs and efforts, and that a large fraction of petroleum-based processes will be replaced with sustainable bioprocesses."
Lee S. Y. & Kim, H. U. Systems Strategies for Developing Industrial Microbial Strains. Nature Biotechnology (2015).
This work was supported by the Technology Development Program to Solve Climate Change on Systems Metabolic Engineering for Biorefineries (NRF-2012M1A2A2026556) and by the Intelligent Synthetic Biology Center through the Global Frontier Project (2011-0031963) from the Ministry of Science, ICT and Future Planning (MSIP), Korea, and through the National Research Foundation (NRF) of Korea. This work was also supported by the Novo Nordisk Foundation.
Picture: Concept of the Systems Metabolic Engineering Framework
(a) Three major bioprocess stages (b) Considerations in systems metabolic engineering to optimize the whole bioprocess. List of considerations for the strain development and fermentation contribute to improving microbial strain's production performance (red), whereas those for the separation and purification help in reducing overall operation costs by facilitating the downstream process (blue). Some of the considerations can be repeated in the course of systems metabolic engineering.
2015.10.19 View 10364 -
Professor Ki-Jun Jeong Wins the 2015 Dam Yeun Academic Award
The 11th Dam Yeun Academic Award presented by the Korean Society for Biotechnology and Bioengineering (KSBB) to a biologist under 45 years old went to Professor Ki-Jun Jeong of the Chemical and Biomolecular Engineering Department at KAIST.
The award ceremony took place on October 13, 2015, at the annual conference of KSBB held at Songdo Convensia in Incheon City.
Each year KSBB announces the recipient of the award based on the publications by researchers in the last five years at peer-reviewed international journals or KSBB Journal as well as the record of patent registration and technology transfers.
Professor Jeong is recognized for his pioneering research in protein, antibody, cellular engineering, and protein displays and chips.
2015.10.19 View 8547 -
KAIST's Moon Soul Graduate School of Future Strategy Names Recipients of Science Journalism Awards
The Science Journalism Masters Program of the Moon Soul Graduate School of Future Strategy at KAIST named the winners of the 2015 Science Journalism Awards on October 17, 2015. The award ceremony took place at KAIST’s Seoul campus.
The awards were created in 2011 to recognize exemplary journalism that has contributed to the advancement of science and technology in Korea.
This year, the Korean Broadcasting System’s science show called the “Jang Yeong-Sil Show” received the Grand Prize. Yeong-Sil Jang was a Korean scientist and astronomer during the Joseon Dynasty in the 14th century.
A television documentary on challenges facing farm-raised chickens, which was produced by the Munhwa Broadcasting Corporation in Jeonju City, won the TV Award, while news coverage by Dong-A Daily on the outbreak of the Middle East respiratory Syndrome (MERS) in Korea received the Print Award.
After the award ceremony, students and professors of the Science Journalism Program hosted a conference to review and discuss major issues covered by the news media in the past year.
2015.10.15 View 6588 -
KAIST's College of Business Places Fourth in the 2015 Better World MBA Ranking
The Corporate Knights, a business and society magazine based in Canada, released the results of the 2015 Better World MBA Ranking on October 8, 2015.
KAIST’s business school ranked fourth globally and, number one in Asia, according to the list.
The 2015 Corporate Knights Better World MBA Ranking included a total of 121 schools; York University’s Schulich School of Business of Canada took first place.
The rankings were based on three criteria: the number of curricula (core and required courses) dedicated to sustainability, the number of research institutions and centers at the business school, and the volume of faculty research focused on better world topics such as sustainable finance, clean energy, or gender diversity.
The Better World MBA Ranking aims to identify business schools that best equip graduates who seek to change the world for the better by offering students opportunities to learn how to integrate social and environmental factors in their understanding of management functions via core MBA courses, faculty expertise, and research centers.
Dean Dong-Seok Kim of the College of Business at KAIST said,
“For years, our school has introduced a wide range of programs and research initiatives that address important social needs and issues. As part of this effort, we created the Graduate School of Green Growth and MBA for Social Entrepreneurship back in 2013. I believe that these endeavors played a favorable role in our receiving high scores in the ranking.”
KAIST’s Graduate School of Green Growth previously ranked sixth in the world’s top Green MBA School list published by Corporate Knights.
For the 2015 Better World MBA Ranking, go to
http://www.corporateknights.com/reports/2015-global-sustainable-mba/11153-14442629/.
2015.10.12 View 5066 -
Professor Key-Sun Choi Receives the Order of Service Merit Green Stripes from the Korean Government
The award recognizes Professor Choi’s life-long research effort to make Korean language digitally available, both nationally and internationally.
Professor Key-Sun Choi of the School of Computing at KAIST received the Order of Service Merit Green Stripes from the Korean government at the 569th Korean Language Day, held annually to commemorate the invention of the Korean language, Hangeul. The ceremony took place on October 9, 2015, at the Sejong Center in Seoul.
Professor Choi has distinguished himself in the field of natural language processing (NLP), including Korean language. He developed a Korean NLP parser that enabled information processing and data analysis of Korean language, as well as a digital Korean dictionary, contributing to the advancement of Korean language-based information technology.
Professor Choi also led the way to widespread use of Korean natural language in computing by developing and commercializing open source software to process the Korean language.
He has served leading roles in many of the international academic societies and standardization organizations, among others, as the vice president of Infoterm (the International Information Center for Terminology), president of the Asia Federation of Natural Language Processing, vice chair of ISO/TC 37, a technical committee in the International Organization for Standardization (ISO), and a council member for the International Association of Machine Translation.
2015.10.08 View 8196 -
Yang-Hann Kim named recipient of the Rossing Prize in Acoustics Education by the Acoustical Society of America
Courtesy of the Acoustical Society of America (ASA)
Press release issued by ASA on October 8, 2015:
Yang-Hann Kim named recipient of the Rossing Prize in Acoustics Education by the Acoustical Society of America
Melville (NY), 8 October 2015—Yang-Hann Kim, Professor at KAIST (Korea Advanced Institute of Science and Technology), Daejeon, has been named recipient of the Acoustical Society of America (ASA) Rossing Prize in Acoustics Education. The Rossing Prize is awarded to an individual who has made significant contributions toward furthering acoustics education through distinguished teaching, creation of educational materials, textbook writing and other activities. The Prize will be presented at the 170th meeting of the ASA on 4 November 2015 in Jacksonville, Florida.
“It is my great honor to receive the Rossing Prize, which has been given to outstanding scholar members of ASA since 2003. I never dreamed to be one of them.” said Kim. “I must express my deep respect and love to my friend Thomas Rossing: I have known him more than 20 years, always respect what he has done for teaching, writing books, and pioneering work in musical acoustics.”
Yang-Hann Kim is a Fellow of the Acoustical Society of America. He received a Ph.D. from the Massachusetts Institute of Technology. His main research interests in acoustics began with “sound visualization” resulted in the development of the “sound camera” which makes any sound visible instantly. Then he moved to “sound manipulation.” Using his manipulation technology, one can move any sound in space and time, positioning sound, and can create a private sound zone. Sound Visualization and Manipulation, (Wiley, 2013), summarizes these two fields. Dr. Kim’s textbook, Sound Propagation: An Impedance Based Approach (John Wiley and Sons, 2010), is well acknowledged by the associated professional communities as one of best acoustics textbooks. Using his teaching experience at KAIST, he created a YouTube lecture on acoustics and vibration which is also available in MOOC (Massive Open Online Course). He has also presented lectures to over 500 engineers and technicians for the past 30 years.
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The Acoustical Society of America (ASA) is the premier international scientific society in acoustics devoted to the science and technology of sound. Its 7000 members worldwide represent a broad spectrum of the study of acoustics. ASA publications include the Journal of the Acoustical Society of America—the world’s leading journal on acoustics, Acoustics Today magazine, books, and standards on acoustics. The Society also holds two major scientific meetings per year. For more information about the Society visit our website, www.acousticalsociety.org.
2015.10.06 View 8692 -
Professor Sang-Min Bae receives the 2015 IDEA Awards
Professor Sang-min Bae of the Industrial Design Department at KAIST garnered one silver and two bronze awards from the 2015 International Design Excellence Awards (IDEA). Along with iF Design Award and Red Dot Design Awards, the IDEA is regarded as one of the world’s most respected recognition in the field of design.
Trash to Bin (T2B), a silver winner in the category of Social Impact Design, is a trash bin made of 1.87 lb (0.85 kg) of discarded papers. Using one-hundred percent recycled paper pulp, each T2B costs under $5 for production. The bin can be fully waterproofed for at least six hours. While satisfying with the industry safety standards, this environmentally-friendly bin can be produced on a large scale using litter energy, but offering the exact same benefit of a general garbage can.
Roll-Di, one of the two bronze winners, is a direction indicator that tells which string of screen curtains should be pulled to make the curtain go up or down. As shown in the picture below, Roll-Di can be installed at the bottom of the string, and the “up and down” arrows show which side of the string needs to be pulled to achieve the desired position of the curtain. This simple, yet handy solution to the problem that people frequently make the mistake of pulling the wrong string provides users with greater convenience.
The other bronze winner is Printing Solar-cell, an organic cartridge module that prints solar-cells using a domestic, ink-jet printer. With Printing Solar-cell, users can design their own cell patterns and charge their electronics anywhere holding the printed solar-cell on a copy paper.
Professor Bae said, “I’ve always tried to design something that is useful for people in need. I consider the IDEA awards an encouragement to keep up with my work toward that goal.”
Trash to Bin
Roll-Di
Printing Solar-cell
2015.09.30 View 7433 -
Discovery of Redox-Switch of KEenzyme Involved in N-Butanol Biosynthesis
Research teams at KAIST and Kyungpook National University (KNU) have succeeded in uncovering the redox-switch of thiolase, a key enzyme for n-butanol production in Clostridium acetobutylicum, one of the best known butanol-producing bacteria.
Biological n-butanol production was first reported by Louis Pasteur in 1861, and the bioprocess was industrialized usingClostridium acetobutylicum. The fermentation process by Clostridium strains has been known to be the most efficient one for n-butanol production. Due to growing world-wide issues such as energy security and climate change, the biological production of n-butanol has been receiving much renewed interest. This is because n-butanol possesses much better fuel characteristics compared to ethanol, such as higher energy content (29.2 MJ/L vs 19.6 MJ/L), less corrosiveness, less hygroscopy, and the ease with which it can be blended with gasoline and diesel.
In the paper published in Nature Communications, a broad-scope, online-only, and open access journal issued by the Nature Publishing Group (NPG), on September 22, 2015, Professor Kyung-Jin Kim at the School of Life Sciences, KNU, and Distinguished Professor Sang Yup Lee at the Department of Chemical and Biomolecular Engineering, KAIST, have proved that the redox-switch of thiolase plays a role in a regulation of metabolic flux in C. acetobutylicum by using in silico modeling and simulation tools.
The research team has redesigned thiolase with enhanced activity on the basis of the 3D structure of the wild-type enzyme. To reinforce a metabolic flux toward butanol production, the metabolic network of C. acetobutylicum strain was engineered with the redesigned enzyme. The combination of the discovery of 3D enzyme structure and systems metabolic engineering approaches resulted in increased n-butanol production in C. acetobutylicum, which allows the production of this important industrial chemical to be cost competitive.
Professors Kim and Lee said, "We have reported the 3D structure of C. acetobutylicum thiolase-a key enzyme involved in n-butanol biosynthesis, for the first time. Further study will be done to produce butanol more economically on the basis of the 3D structure of C. acetobutylicum thiolase."
This work was published online in Nature Communications on September 22, 2015.
Reference: Kim et al. "Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum," Nature Communications
This research was supported by the Technology Development Program to Solve Climate Changes from the Ministry of Education, Science and Technology (MEST), Korea, the National Research Foundation of Korea, and the Advanced Biomass Center through the Global Frontier Research Program of the MEST, Korea.
For further information, contact Dr. Sang Yup Lee, Distinguished Professor, KAIST, Daejeon, Korea (leesy@kaist.ac.kr, +82-42-350-3930); and Dr. Kyung-Jin Kim, Professor, KNU, Daegu, Korea (kkim@knu.ac.kr, +82-53-950-6088).
Figure 1: A redox-switch of thiolase involves in butanol biosynthesis in Clostridium acetobutylicum. Thiolase condenses two acetyl-CoA molecules for initiating four carbon flux towards butanol.
Figure 2: Thiolase catalyzes the condensation reaction of acetyl-CoA to acetoacetyl-CoA. Two catalytic cysteine residues at 88th and 378th are oxidized and formed an intermolecular disulfide bond in an oxidized status, which results in inactivation of the enzyme for n-butanol biosynthesis. The intermolecular disulfide bond is broken enabling the n-butanol biosynthesis, when the environment status is reduced.
2015.09.23 View 10344 -
KAIST and Chongqing University of Technology in China Open an International Program
With the help of KAIST, Chongqing University of Technology (CQUT) in China established an electrical engineering and computer science program and admitted their first 66 freshmen this fall semester.
The joint program was created to foster skilled engineers in the fields of electrical engineering and computer science, which are necessary for the development of the Korean and Chinese Industrial Complex located in Chongqing City.
KAIST has provided CQUT with a majority of the program’s curricula currently offered to its students in Daejeon, Korea.
Under the jointly administered program, KAIST takes on education and research while CQUT is responsible for student selection and administration.
KAIST has dispatched eight professors to teach the related fields in English, and 17 CQUT professors will teach the rest of the curricula.
In August 2014, KAIST and CQUT singed a cooperation agreement for education and research exchange and created the CQUT-KAIST Education Cooperation Center, which is headed by Professor Young-Nam Han of the Electrical Engineering Department at KAIST.
The two universities will expand their collaboration to include graduate programs by 2016.
In the picture below, President Steve Kang of KAIST (right) shakes hands with President Shi Xiaohui of Chongqing University of Technology (left).
2015.09.17 View 9572