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Professor Sang-Yup Lee Receives the Order of Service Merit Red Stripes from the Korean Government
The government of the Republic of Korea named Professor Sang-Yup Lee of the Department of Chemical and Bio-molecular Engineering at KAIST as the fiftieth recipient of the Order of Service Merit Red Stripes on May 19, 2015.
This medal is awarded to government employees, officials, and teachers in recognition of their contributions to public services including education.
Professor Lee is regarded as a leading scientist in the field of metabolic engineering, genomics, proteomics, metabolomics, and bioinformatics on microorganism producing various primary and secondary metabolites. He contributed significantly to the advancement of bio-based engineering research in Korea.
In addition, his research in microorganism metabolic engineering propelled him to the front of his field, making him the world’s founder of systems metabolic engineering, inventing numerous technologies in strain development.
Professor Lee has received many patent rights in bioprocess engineering. While at KAIST, he applied for 585 patents and registered 227 patents. In particular, he has applied for 135 patents and registered 99 patents in the past five years, successfully turning research results into commercial applications.
Professor Lee said, “I’m glad to contribute to the development of Korean science and technology as a researcher and teacher. I would like to share this honor with my students, master’s and doctoral students in particular, because without their support, it wouldn’t have been possible to pull off the highest level of research results recognized by this medal.”
2015.05.21 View 7299 -
KAIST to Host Conference on the Financial Technology Industry
To take place in the Korea Federation of Banks building on May 21, 2015, Seoul
Around 200 individuals to be present including Oh-Kyu Kwon, the former Minister of Finance and Economy and Chang-Hyun Yun, the former president of Korea Institute of Finance
KAIST will hold a conference to discuss prospects for Korea’s financial technology industry (FinTech) and to address the rapid changes taking place in both national and global finance markets.
The conference will be held in the Convention Hall of the Korea Federation of Banks building in Myeongdong, Seoul on May 21, 2015 with a theme entitled “The Challenge and the Task of Korean FinTech Industry in the Global Finance Market.”
Around 200 individuals including Oh-Kyu Kwon, the former Minister of Finance and Economy, Jiwon Jung, a member of a standing committee of Financial Services Commission, and Steve Kang, the President of KAIST will attend the meeting.
The term “FinTech” originates from the combination of two words, finance and technology, to describe a new form of financial system based on Information Technology (IT). The precise definition and boundary of FinTech is not fully established yet, but this will provide Korea with an opportunity to take the lead in the finance industry with its cutting-edge IT.
The conference will focus on the methods by which Korean FinTech companies can acquire a competitive edge in the global finance market. The keynote speaker, Tong-Suk Kim, the Dean of College of Business, KAIST, will speak about “The Challenge and the Task of Korean FinTech.” The talk will emphasize how the FinTech industry can create an innovative industry, destroying the existing paradigm of payment system and Internet-only banks.
The keynote speech will be followed by a talk on “The Requirements for Establishing Korean FinTech Ecosystem” by Jong-Hyun Kim, a researcher at Woori Finance Research Institute, Korea.
Additional talks, which will be given by KAIST professors, are:
“Korean Economy and the Role of FinTech” by Professor Young-Sun Kwon of the Department Business and Technology Management;
“Korean FinTech in ICT Perspective” by Professor Yoon-Joon Lee of the Department of Computer Science;
“The Current State and Possibilities of Korean FinTech” by Professor Byung-Tae Lee of the School of Management Engineering; and
“The Task and Challenge of Promoting FinTech Industry” by Professor Byung-Chun Kim of the School of Management Engineering.
Also, Professor Chang-Hyun Yoon of the School of Business Administration, University of Seoul, will give a talk on “The Crisis in Korean Finance Industry and the Role of FinTech.”
The conference will also hold a discussion session on “The Promotion Methods for Korean FinTech Industry.” Participants for the discussion will include Jae-Sung Song from the Ministry of Science, ICT and Future Planning, Dong-Hwan Kim from the Financial Services Commission, Jeon Jin from Samsung Economic Research Institute (SERI), Hyo-Jin Lee of 8Percent, In-Chang Hwang from the Korea Insurance Research Institute, and Jae-Kyu Lee from Koscom.
Byung-Chun Kim, the Director of KAIST’s Financial Engineering Research Center, who organized the FinTech conference said, “FinTech industry will evolve from simply attempting to attract consumers to understanding the lifestyle patterns of consumers to provide customized service and information.”
2015.05.20 View 8389 -
KAIST Holds a Ceremony to Present the Cho Jeong-Hoon Academic Award
Doctor Gyu-Tae Kim from General Electric (GE) received the eleventh Cho Jeong-Hoon Academic Award. The award ceremony took place in the main conference room of the administration building on campus on May 13, 2015.
Dr. Kim, a graduate of KAIST, conducts research in the field of instable swirl combustion of gas turbines and has contributed to the development of aircraft engines. He earned his name as a researcher by identifying, for the first time in the world, the correlation between the thermoacoustic instability of gas turbine engines and the complex response of swirl flames.
Along with Dr. Kim, Shin-Jae Kang of the Aerospace Engineering Department, KAIST, Yong-Gyun Bae of the Mechanical Engineering Department, Korea University, and Ji-Won Kim from Kongju National University High School, received the Cho Jeong-Hoon scholarship.
The award was created in commemoration of Cho Jeong-Hoon who was killed in an explosion during his research at the KAIST Rocket Laboratory on May 13, 2003. Cho’s parents donated USD 450,000 to KAIST in his memory. Since 2005, a total of four students from KAIST, Korea University, and Kongju National University High School, all of which the late Honorary Doctor Cho attended, have received the scholarship.
2015.05.19 View 6863 -
KAIST's Patina Engraving System Awarded at ACM CHI
Professor Tek-Jin Nam’s research team of the Industrial Design Department of KAIST received the Best Paper Award in the 2015 Association for Computing Machinery’s (ACM) Conference on Human Factors in Computing Systems (CHI) which was held from April 18 to 23, 2015. The team consisted of two KAIST students: Moon-Hwan Lee, a Ph.D. candidate, and Sejin Cha, a master's student. The team was the first in Asia to receive the award.
The ACM CHI represents the premier conference in the field of Human-Computer Interaction (HCI). This year’s event, held in Seoul, South Korea, was the first conference that the ACM had held in Asia in its thirty-three year history. The KAIST team’s paper, entitled “Patina Engraver: Visualizing Activity Logs as Patina in Fashionable Trackers,” ranked in the top 1% of 2,000 submitted papers.
The team developed Patina Engraver, an activity tracker, which monitors and tracks fitness-related metrics such as distances walked or run, calorie consumption, heartbeat, sleep quality, and blood pressure. The device wirelessly connects to a computer or smartphone so that it can store and utilize long-term tracking data.
However, what makes Patina Engraver, a smart wristband, different from other health trackers is its ability to display different design patterns based on users’ activity on the surface of the wristband. The research team was inspired to build this system from the fact that wearable electronics including activity trackers can be used not only as health care devices, but also as fashion items to express emotions and personalities.
Equipped with an engraving feature, the charging pad or holder for Patina Engraver draws individualized patterns to reflect the user’s activities, such as walking or running, while the device is being charged. The pattern display syncs with the frequency of usage, therefore, the more the tracker is used, the greater the number of patterns will show up.
According to the team, since Patina Engraver provides users with a personalized illustration of their activity on the tracker, users are more motivated to put on the tracker and exercise.
Professor Nam said, “This research can be applied in producing other wearable devices to enhance users’ emotional satisfaction. When wearable technology is combined with design and emotion, the industry market will quickly expand.”
Figure 1: Patina engraving system developed by KAIST research team
Figure 2: The process of engraving illustrations of the activity records onto the tracker
Figure 3: Personalized activity trackers based on activity records
2015.05.15 View 12032 -
KAIST Hosts the Wearable Computer Contest 2015
Deadlines for Prototype Contest by May 30, 2015 and August 15 for Idea Contest
KAIST will hold the Wearable Computer Contest 2015 in November, which will be sponsored by Samsung Electronics Co., Ltd.
Wearable computers have emerged as next-generation mobile devices, and are gaining more popularity with the growth of the Internet of Things. KAIST has introduced wearable devices such as K-Glass 2, a smart glass with augmented reality embedded. The Glass also works on commands by blinking eyes.
This year’s contest with the theme of “Wearable Computers for Internet of Things” is divided into two parts: the Prototype Competition and Idea Contest.
With the fusion of information technology (IT) and fashion, contestants are encouraged to submit prototypes of their ideas by May 30, 2015. The ten teams that make it to the finals will receive a wearable computer platform and Human-Computer Interaction (HCI) education, along with a prize of USD 1,000 for prototype production costs. The winner of the Prototype Contest will receive a prize of USD 5,000 and an award from the Minister of Science, ICT and Future Planning (MSIP) of the Republic of Korea.
In the Idea Contest, posters containing ideas and concepts of wearable devices should be submitted by August 15, 2015. The teams that make it to the finals will have to display a life-size mockup in the final stage. The winner of the contest will receive a prize of USD 1,000 and an award from the Minister of MSIP.
Any undergraduate or graduate student in Korea can enter the Prototype Competition and anyone can participate in the Idea Contest.
The chairman of the event, Hoi-Jun Yoo, a professor of the Department of Electrical Engineering at KAIST, noted:
“There is a growing interest in wearable computers in the industry. I can easily envisage that there will be a new IT world where wearable computers are integrated into the Internet of Things, healthcare, and smart homes.”
More information on the contest can be found online at http://www.ufcom.org.
Picture: Finalists in the last year’s contest
2015.05.11 View 7183 -
Jong Hoon Kim, a former president of Bell Labs, speaks at KAIST
Dr. Jong-Hoon Kim, who was the youngest person to serve as the President of Bell Labs and selected as one of the ten most influential Asian-Americans, will give a lecture at KAIST at 5 pm on April 28, 2015 in the KI building.
In 1992, Dr. Kim founded a telecommunication company, Yurie System. After listing the company on NASDAQ, he sold the company to Lucent Technologies for USD one billion. Dr. Kim served as the President of Lucent Technologies, taught as the University of Maryland, and subsequently served as the President of Bell Labs. He is currently the President of Kiswe Mobile.
In his lecture entitled “Aim High, Take Action,” Dr. Kim will share his personal stories and speak about ways young people can set goals for future and put those into practice. He will focus on his experiences in the United States to list his own company, Yurie System, on NASDAQ and to sell the company as well as the management innovations, which he brought about during his presidency at Bell Labs.
KAIST and Kiswe Mobile have been cooperating on a project, "Global Entrepreneurship by Doing," since 2014 to foster entrepreneurship in Korean youth. While working for Kiswe Mobile in the United States, KAIST students will have an opportunity to conduct project management, market research, and marketing, and to build local networks.
The details of the program can be found on the website of the KAIST Center for Science-based Entrepreneurship, http://eship.kaist.ac.kr.
2015.04.27 View 5716 -
KAIST Researchers Develops Hyper-Stretchable Elastic-Composite Energy Harvester
A research team led by Professor Keon Jae Lee (http://fand.kaist.ac.kr) of the Department of Materials Science and Engineering at KAIST has developed a hyper-stretchable elastic-composite energy harvesting device called a nanogenerator.
Flexible electronics have come into the market and are enabling new technologies like flexible displays in mobile phone, wearable electronics, and the Internet of Things (IoTs). However, is the degree of flexibility enough for most applications? For many flexible devices, elasticity is a very important issue. For example, wearable/biomedical devices and electronic skins (e-skins) should stretch to conform to arbitrarily curved surfaces and moving body parts such as joints, diaphragms, and tendons. They must be able to withstand the repeated and prolonged mechanical stresses of stretching. In particular, the development of elastic energy devices is regarded as critical to establish power supplies in stretchable applications. Although several researchers have explored diverse stretchable electronics, due to the absence of the appropriate device structures and correspondingly electrodes, researchers have not developed ultra-stretchable and fully-reversible energy conversion devices properly.
Recently, researchers from KAIST and Seoul National University (SNU) have collaborated and demonstrated a facile methodology to obtain a high-performance and hyper-stretchable elastic-composite generator (SEG) using very long silver nanowire-based stretchable electrodes. Their stretchable piezoelectric generator can harvest mechanical energy to produce high power output (~4 V) with large elasticity (~250%) and excellent durability (over 104 cycles). These noteworthy results were achieved by the non-destructive stress- relaxation ability of the unique electrodes as well as the good piezoelectricity of the device components. The new SEG can be applied to a wide-variety of wearable energy-harvesters to transduce biomechanical-stretching energy from the body (or machines) to electrical energy.
Professor Lee said, “This exciting approach introduces an ultra-stretchable piezoelectric generator. It can open avenues for power supplies in universal wearable and biomedical applications as well as self-powered ultra-stretchable electronics.”
This result was published online in the March issue of Advanced Materials, which is entitled “A Hyper-Stretchable Elastic-Composite Energy Harvester.”
YouTube Link: “A hyper-stretchable energy harvester”
https://www.youtube.com/watch?v=EBByFvPVRiU&feature=youtu.be
Figure: Top row: Schematics of hyper-stretchable elastic-composite generator enabled by very long silver nanowire-based stretchable electrodes.
Bottom row: The SEG energy harvester stretched by human hands over 200% strain.
2015.04.14 View 12829 -
KAIST Hosts a Symposium on IPR
KAIST’s Graduate School of Future Strategy (http://futures.kaist.ac.kr) hosted a symposium entitled “Future Strategies to Grow Korea as the Hub for the World’s Intellectual Property Rights (IPRs)” under the theme of “Patent Laws and a Revised Bill for the Code of Civil Procedures” in the National Assembly’s Memorial Hall on April 9, 2015.
Experts who attended the symposium included Professor James Dator, Director of the Hawaii Research Center for Futures Studies, Sang-Wook Han, a lawyer and Vice President of Korea Intellectual Property Protection Association (KIPRA), and Min Seo, a former Chairman of Civil Law Revision Commission of the Ministry of Justice, Korea.
The event consisted of special lectures, patent law presentations, a revised bill for the code of civil procedures in patent law, and a general discussion forum. Professor Dator, the keynote speaker, addressed the future of intellectual property. San-Wook Han (KIPRA) talked about new and effective changes in Korean patent law such as the compensation against IPR violations and the reduction of legal burden of proof in IPR disputes. Min Seo from the Ministry of Justice moderated a panel of eight members, which offered an in-depth discussion on the revised bill.
A ceremony for “The Third Future Strategy Award” was also held at the symposium. Yeon-Soo Park, former Administrator of the National Emergency Management Agency, received the award for his work on the Northeast Asian International Business Center City Project which enabled the construction of Incheon International Airport and Songdo International City.
2015.04.09 View 9980 -
Professor Rim Presents at IAEA Workshop in Vienna
Professor Chun-Taek Rim of the Department of Nuclear and Quantum Engineering at KAIST recently attended the International Atomic Energy Agency (IAEA)’s workshop on the Application of Wireless Technologies in Nuclear Power Plant Instrumentation and Control System. It took place on March 30-April 2, 2015, in Vienna, Austria.
Representing Korea, Professor Rim gave a talk entitled “Highly Reliable Wireless Power and Communications under Severe Accident of Nuclear Power Plants (NPPs).” About 20 industry experts from 12 countries such as AREVA (France), Westinghouse (US), Oak Ridge National Laboratory (US), Hitachi (Japan), and ENEA (Italy) joined the meeting.
The IAEA hosted the workshop to explore the application of wireless technology for the operation and management of NPPs. It formed a committee consisting of eminent professionals worldwide in NPP instrumentation and control systems, communications, and nuclear power to examine this issue in-depth and to conduct various research projects for the next three years.
In particular, the committee will concentrate its research on improving the reliability and safety of using wireless technology, not only in the normal operation of nuclear plants but also in extreme conditions such as the Fukushima Daiichi nuclear accident. The complementation, economic feasibility, and standardization of NPPs when applying wireless technology will be also discussed.
Professor Rim currently leads the Nuclear Power Electronics
and Robotics Lab at KAIST (http://tesla.kaist.ac.kr/index_eng.php?lag=eng).
Picture 1: Professors Rim presents his topic at the IAEA Workshop in Vienna.
Picture 2: The IAEA Workshop Participants
2015.04.07 View 11323 -
Anti-Cancer Therapy Delivering Drug to an Entire Tumor Developed
KAIST’s Department of Bio and Brain Engineering Professor Ji-Ho Park and his team successfully developed a new highly efficacious anti-cancer nanotechnology by delivering anti-cancer drugs uniformly to an entire tumor. Their research results were published in Nano Letters online on March 31, 2015.
To treat inoperable tumors, anti-cancer medicine is commonly used. However, efficient drug delivery to tumor cells is often difficult, treating an entire tumor with drugs even more so.
Using the existing drug delivery systems, including nanotechnology, a drug can be delivered only to tumor cells near blood vessels, leaving cells at the heart of a tumor intact. Since most drugs are injected into the bloodstream, tumor recurrence post medication is frequent.
Therefore, the team used liposomes that can fuse to the cell membrane and enter the cell. Once inside liposomes the drug can travel into the bloodstream, enter tumor cells near blood vessels, where they are loaded to exosomes, which are naturally occurring nanoparticles in the body. Since exosomes can travel between cells, the drug can be delivered efficiently into inner cells of the tumor.
Exosomes, which are secreted by cells that exist in the tumor microenvironment, is known to have an important role in tumor progression and metastasis since they transfer biological materials between cells. The research team started the investigation recognizing the possibility of delivering the anti-cancer drug to the entire tumor using exosomes.
The team injected the light-sensitive anti-cancer drug using their new delivery technique into experimental mice. The researchers applied light to the tumor site to activate the anti-cancer treatment and analyzed a tissue sample. They observed the effects of the anti-cancer drug in the entire tumor tissue.
The team’s results establish a ground-breaking foothold in drug delivery technology development that can be tailored to specific diseases by understanding its microenvironment. The work paves the way to more effective drug delivery systems for many chronic diseases, including cancer tumors that were difficult to treat due to the inability to penetrate deep into the tissue.
The team is currently conducting experiments with other anti-cancer drugs, which are being developed by pharmaceutical companies, using their tumor-penetrating drug delivery nanotechnology, to identify its effects on malignant tumors.
Professor Park said, “This research is the first to apply biological nanoparticles, exosomes that are continuously secreted and can transfer materials to neighboring cells, to deliver drugs directly to the heart of tumor.”
Picture: Incorporation of hydrophilic and hydrophobic compounds into membrane vesicles by engineering the parental cells via synthetic liposomes.
2015.04.07 View 11094 -
Professor Shim Featured with His Drone System in IEEE Spectrum
The IEEE Spectrum, a technology and science magazine published by the Institute of Electrical and Electronics Engineers (IEEE), featured an article of KAIST’s autonomous unmanned aerial vehicles (UAVs) entitled “South Korea Prepares for Drone vs. Drone Combat,” posted on April 1, 2015.
The article introduces the anti-drone defense system being developed by Professor “David” Hyunchul Shim of the Department of Aerospace Engineering at KAIST. With the goal of developing guard drones that can detect and capture unknown UAVs, the anti-drone defense system consists of reconnaissance drones, agile multi-rotor UAVs equipped with nets which are dropped to snare enemy drones, and transport UAVs to carry smaller drones.
Professor Shim currently leads KAIST’s Unmanned System Research Group (USRG, http://unmanned.kaist.ac.kr/) and Center of Field Robotics for Innovation, Exploration, aNd Defense (C-FRIEND).
For the article, please go to http://spectrum.ieee.org/automaton/robotics/aerial-robots/south-korea-drone-vs-drone.
2015.04.02 View 11470 -
Mystery in Membrane Traffic How NSF Disassembles Single SNAR Complex Solved
KAIST researchers discovered that the protein N-ethylmaleimide-sensitive factor (NSF) unravels a single SNARE complex using one round ATP turnover by tearing the complex with a single burst, contradicting a previous theory that it unwinds in a processive manner.
In 2013, James E. Rothman, Randy W. Schekman, and Thomas C. Südhof won the Nobel Prize in Physiology or Medicine for their discoveries of molecular machineries for vesicle trafficking, a major transport system in cells for maintaining cellular processes. Vesicle traffic acts as a kind of “home-delivery service” in cells. Vesicles package and deliver materials such as proteins and hormones from one cell organelle to another. Then it releases its contents by fusing with the target organelle’s membrane. One example of vesicle traffic is in neuronal communications, where neurotransmitters are released from a neuron. Some of the key proteins for vesicle traffic discovered by the Nobel Prize winners were N-ethylmaleimide-sensitive factor (NSF), alpha-soluble NSF attachment protein (α-SNAP), and soluble SNAP receptors (SNAREs).
SNARE proteins are known as the minimal machinery for membrane fusion. To induce membrane fusion, the proteins combine to form a SNARE complex in a four helical bundle, and NSF and α-SNAP disassemble the SNARE complex for reuse. In particular, NSF can bind an energy source molecule, adenosine triphosphate (ATP), and the ATP-bound NSF develops internal tension via cleavage of ATP. This process is used to exert great force on SNARE complexes, eventually pulling them apart. However, although about 30 years have passed since the Nobel Prize winners’ discovery, how NSF/α-SNAP disassembled the SNARE complex remained a mystery to scientists due to a lack in methodology.
In a recent issue of Science, published on March 27, 2015, a research team, led by Tae-Young Yoon of the Department of Physics at the Korea Advanced Institute of Science and Technology (KAIST) and Reinhard Jahn of the Department of Neurobiology of the Max-Planck-Institute for Biophysical Chemistry, reports that NSF/α-SNAP disassemble a single SNARE complex using various single-molecule biophysical methods that allow them to monitor and manipulate individual protein complexes.
“We have learned that NSF releases energy in a burst within 20 milliseconds to “tear” the SNARE complex apart in a one-step global unfolding reaction, which is immediately followed by the release of SNARE proteins,” said Yoon.
Previously, it was believed that NSF disassembled a SNARE complex by unwinding it in a processive manner. Also, largely unexplained was how many cycles of ATP hydrolysis were required and how these cycles were connected to the disassembly of the SNARE complex.
Yoon added, “From our research, we found that NSF requires hydrolysis of ATPs that were already bound before it attached to the SNAREs—which means that only one round of an ATP turnover is sufficient for SNARE complex disassembly. Moreover, this is possible because NSF pulls a SNARE complex apart by building up the energy from individual ATPs and releasing it at once, yielding a “spring-loaded” mechanism.”
NSF is a member of the ATPases associated with various cellular activities family (AAA+ ATPase), which is essential for many cellular functions such as DNA replication and protein degradation, membrane fusion, microtubule severing, peroxisome biogenesis, signal transduction, and the regulation of gene expression. This research has added valuable new insights and hints for studying AAA+ ATPase proteins, which are crucial for various living beings.
The title of the research paper is “Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover.” (DOI: 10.1126/science.aaa5267)
Youtube Link: https://www.youtube.com/watch?v=FqTSYHtyHWE&feature=youtu.be
Picture 1. Working model of how NSF/α-SNAP disassemble a single SNARE complex
Picture 2. After neurotransmitter release, NSF disassembles a single SNARE complex using a single round of ATP turnover in a single burst reaction.
2015.03.28 View 9992