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Professor Yim Decorated with the Chongjo Order of Merit
Professor Yong-Taek Yim from the Department of Mechanical Engineering was awarded the highest order of merit, the “Chongjo Keunjong Medal,” bestowed to public officials by the government in celebration of Invention Day on May 27.
Professor Yim was recognized for his innovative achievements to increase royalty income by introducing an IP-based management system at the Korean Institute of Machinery & Materials. He served as the president of KIMM for three years from 2014.
His idea led to new approaches to help explore diverse revenue creating sources such as dividend earnings and share sales, apart from simply relying on technology transfer fees. His efforts to disseminate the in-house R&D results also led to the foundation of six tech-based startups and spinoffs, which generated 11.2 billion KRW in sales. He also helped set up three spinoffs abroad.
Professor Yim said, “I pushed employee invention as a new value creator at KIMM. I thank each and every researcher and staff member at KIMM who worked so hard to create such an innovative IP-based R&D environment.”
2019.05.28 View 6457 -
5 Biomarkers for Overcoming Colorectal Cancer Drug Resistance Identified
< Professor Kwang-Hyun Cho's Team >
KAIST researchers have identified five biomarkers that will help them address resistance to cancer-targeting therapeutics. This new treatment strategy will bring us one step closer to precision medicine for patients who showed resistance.
Colorectal cancer is one of the most common types of cancer worldwide. The number of patients has surpassed 1 million, and its five-year survival rate significantly drops to about 20 percent when metastasized. In Korea, the surge of colorectal cancer has been the highest in the last 10 years due to increasing Westernized dietary patterns and obesity. It is expected that the number and mortality rates of colorectal cancer patients will increase sharply as the nation is rapidly facing an increase in its aging population.
Recently, anticancer agents targeting only specific molecules of colon cancer cells have been developed. Unlike conventional anticancer medications, these selectively treat only specific target factors, so they can significantly reduce some of the side-effects of anticancer therapy while enhancing drug efficacy.
Cetuximab is the most well-known FDA approved anticancer medication. It is a biomarker that predicts drug reactivity and utilizes the presence of the ‘KRAS’ gene mutation. Cetuximab is prescribed to patients who don’t carry the KRAS gene mutation.
However, even in patients without the KRAS gene mutation, the response rate of Cetuximab is only about fifty percent, and there is also resistance to drugs after targeted chemotherapy. Compared with conventional chemotherapy alone, the life expectancy only lasts five months on average.
In research featured in the FEBS Journal as the cover paper for the April 7 edition, the KAIST research team led by Professor Kwang-Hyun Cho at the Department of Bio and Brain Engineering presented five additional biomarkers that could increase Cetuximab responsiveness using systems biology approach that combines genomic data analysis, mathematical modeling, and cell experiments. The experimental inhibition of newly discovered biomarkers DUSP4, ETV5, GNB5, NT5E, and PHLDA1 in colorectal cancer cells has been shown to overcome Cetuximab resistance in KRAS-normal genes. The research team confirmed that when suppressing GNB5, one of the new biomarkers, it was shown to overcome resistance to Cetuximab regardless of having a mutation in the KRAS gene.
Professor Cho said, “There has not been an example of colorectal cancer treatment involving regulation of the GNB5 gene.” He continued, “Identifying the principle of drug resistance in cancer cells through systems biology and discovering new biomarkers that could be a new molecular target to overcome drug resistance suggest real potential to actualize precision medicine.”
This study was supported by the National Research Foundation of Korea (NRF) and funded by the Ministry of Science and ICT (2017R1A2A1A17069642 and 2015M3A9A7067220).
Image 1. The cover of FEBS Journal for April 2019
2019.05.27 View 58351 -
Professor Yim Appointed As Associate Editor of Nuclear Technology
Professor Man-Sung Yim from the Department of Nuclear and Quantum Engineering was appointed as the associate editor (for the Asian region) of Nuclear Technology ― a leading international research journal of the American Nuclear Society. Professor Yim will serve his term for three years from May 2019.
The American Nuclear Society, established in 1954, is comprised of more than 11,000 global members and aims to advance nuclear science, engineering, and technology while supporting the peaceful and beneficial applications of nuclear energy. Since its first publication in 1971, Nuclear Technology has been a representative journal of the society, reporting state-of-the-art information on all phases of the practical applications of nuclear technology.
Professor Yim is being recognized worldwide for his pioneering nuclear education, research, and policy studies in the fields of non-proliferation, safeguards for severe accident management, and waste management. He served as the head professor of the Department of Nuclear and Quantum Engineering and established the Nonproliferation Education and Research Center (NEREC) at KAIST.
Professor Yim remarked, “Asia has an important role to play at the forefront of the world’s nuclear research considering that nuclear development is most actively being carried out in the Asian region these days.”
2019.05.17 View 7039 -
Engineered Microbial Production of Grape Flavoring
(Image 1: Engineered bacteria that produce grape flavoring.)
Researchers report a microbial method for producing an artificial grape flavor. Methyl anthranilate (MANT) is a common grape flavoring and odorant compound currently produced through a petroleum-based process that uses large volumes of toxic acid catalysts.
Professor Sang-Yup Lee’s team at the Department of Chemical and Biomolecular Engineering demonstrated production of MANT, a naturally occurring compound, via engineered bacteria. The authors engineered strains of Escherichia coli and Corynebacetrium glutamicum to produce MANT through a plant-based engineered metabolic pathway.
The authors tuned the bacterial metabolic pathway by optimizing the levels of AAMT1, the key enzyme in the process. To maximize production of MANT, the authors tested six strategies, including increasing the supply of a precursor compound and enhancing the availability of a co-substrate. The most productive strategy proved to be a two-phase extractive culture, in which MANT was extracted into a solvent. This strategy produced MANT on the scale of 4.47 to 5.74 grams per liter, a significant amount, considering that engineered microbes produce most natural products at a scale of milligrams or micrograms per liter.
According to the authors, the results suggest that MANT and other related molecules produced through industrial processes can be produced at scale by engineered microbes in a manner that would allow them to be marketed as natural one, instead of artificial one.
This study, featured at the Proceeding of the National Academy of Sciences of the USA on May 13, was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries from the Ministry of Science and ICT.
(Image 2. Overview of the strategies applied for the microbial production of grape flavoring.)
2019.05.15 View 53956 -
Autophagy in Dendritic Cells Helps Anticancer Activity
Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell anticancer activity.
Autophagy is a process of maintaining cell homeostasis by removing cellular waste and damaged cellular organelles; nevertheless, its role in the presentation of phagocytized tumor-associated antigens remains vague.
Meanwhile, dendritic cells are the ones that recognize pathogens or cancer antigens, and induce immune responses in T cells. When cancer cells are killed by radiation or an anticancer drug, dendritic cells absorb and remove them and present antigens on their surface to transfer them to T-cells.
Professor Heung Kyu Lee from the Graduate School of Medical Science and Engineering and his team found that the autophagy of dendritic cells plays a key role in T-cell activation and they proposed the principles of enhancing anti-cancer effects.
Their experiments showed that T-cell activation of dendritic cells as well as anticancer immune response dropped when there is a deficiency of Atg5 (autophagy-related) in dendritic cells.
Interestingly, Atg5-deficient dendritic cells significantly elevated receptor CD36 on the surface of the cells, which increased the phagocytosis of apoptotic tumor cells yet restricted the activation of T-cells.
At this time, when introducing antibodies into the system in order to block the receptor CD36, the anti-tumor T-cell response increased substantially while tumor growth declined.
Professor Lee said, “This study allowed us to explore the role of autophagy in the anti-cancer immune response of T-cells. We look forward to developing targeted anti-cancer therapies using the receptor CD36.”
This research was published in Autophagy (10.1080/15548627.2019.1596493) on March 22, 2019.
Figure 1.Mechanism of autophagy in dendritic cells
Figure 2. A role of autophagy in dendritic cells
2019.05.13 View 50467 -
Education Innovation Day Reaffirms Rewarding of Excellence
Professors Tae-Eog Lee and Il-Chul Moon from the Department of Industrial & Systems Engineering received the Linkgenesis Best Teacher Award and the Soo-Young Lee Teaching Innovation Award on May 10. They were each awarded with 10 million KRW in prize money during the Education Innovation Day ceremony held at the Chung Kun-mo conference hall.
The award was endowed by KAIST Alumni Scholarship Chairman Hyung-Kyu Lim and KAIST Foundation Chairman Soo-Young Lee to support the innovation initiative and acknowledge faculty members who made significant contributions to educational innovation and benefited the general public though their innovations.
“KAIST’s vision for excellence and commitment to innovation is a game changer. Educational innovation is one of five pillars of Vision 2031, and it is our priority to foster critical and creative thinking students,” said President Sung-Chul Shin at the ceremony. All the awardees made presentation on their innovative projects and shared their ideas on better pedagogical methodology for next generation.
Professor Lee, dean of the KAIST Academy and the head of the Center for Excellence in Learning & Teaching was recognized for his contribution to enhancing educational quality through innovative learning and teaching methodology development. He has set up an Education 3.0 Initiative, an online education platform for flipped learning at KAIST.
Professor Moon also upgraded the online education platform to the 4.0 version and extended KAIST’s massive online courses through KOOC framework. This open platform offers more than 62 courses, with more than 170 thousand users registered since 2014.
Professor Song-Hong Park from the Department of Bio and Brain Engineering and Professor Jae-Woo Lee from the Department of Chemical and Biomolecular Engineering also won the Excellence Award.
2019.05.10 View 7899 -
KAIST Identifies the Cause of Sepsis-induced Lung Injury
(Professor Pilhan Kim from the Graduate School of Medical Science and Engineering)
A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system. They found a type of leukocyte called neutrophils aggregate inside the capillaries during sepsis-induced acute lung injury (ALI), leading to disturbances and dead space in blood microcirculation.
According to the researchers, this phenomenon is responsible for tissue hypoxia causing lung damage in the sepsis model, and mitigating neutrophils improves microcirculation as well as hypoxia.
The lungs are responsible for exchanging oxygen with carbon dioxide gases during the breathing process, providing an essential function for sustaining life. This gas exchange occurs in the alveoli, each surrounded by many capillaries containing the circulating red blood cells.
Researchers have been making efforts to observe microcirculation in alveoli, but it has been technically challenging to capture high-resolution images of capillaries and red blood cells inside the lungs that are in constant breathing motion.
Professor Pilhan Kim from the Graduate School of Medical Science and Engineering and his team developed an ultra-fast laser scanning confocal microscope and an imaging chamber that could minimize the movement of a lung while preserving its respiratory state. They used this technology to successfully capture red blood cell circulation inside the capillaries of animal models with sepsis.
During the process, they found that hypoxia was induced by the increase of dead space inside the lungs of a sepsis model, a space where red blood cells do not circulate. This phenomenon is due to the neutrophils aggregating and trapping inside the capillaries and the arterioles. It was also shown that trapped neutrophils damage the lung tissue in the sepsis model by inhibiting microcirculation as well as releasing reactive oxygen species.
Further studies showed that the aggregated neutrophils inside pulmonary vessels exhibit a higher expression of the Mac-1 receptor (CD11b/CD18), which is a receptor involved in intercellular adhesion, compared to the neutrophils that normally circulate. Additionally, they confirmed that Mac-1 inhibitors can improve inhibited microcirculation, ameliorate hypoxia, while reducing pulmonary edema in the sepsis model.
Their high-resolution 3D intravital microscope technology allows the real-time imaging of living cells inside the lungs. This work is expected to be used in research on various lung diseases, including sepsis.
The research team’s pulmonary circulation imaging and precise analytical techniques will be used as the base technology for developing new diagnostic technologies, evaluating new therapeutic agents for various diseases related to microcirculation.
Professor Kim said, “In the ALI model, the inhibition of pulmonary microcirculation occurs due to neutrophils. By controlling this effect and improving microcirculation, it is possible to eliminate hypoxia and pulmonary edema – a new, effective strategy for treating patients with sepsis.”
Their 3D intravital microscope technology was commercialized through IVIM Technology, Inc., which is a faculty startup at KAIST. They released an all-in-one intravital microscope model called ‘IVM-CM’ and ‘IVM-C’. This next-generation imaging equipment for basic biomedical research on the complex pathophysiology of various human diseases will play a crucial role in the future global bio-health market.
This research, led by Dr. Inwon Park from the Department of Emergency Medicine at Seoul National University Bundang Hospital and formally the Graduate School of Medical Science and Engineering at KAIST, was published in the European Respiratory Journal (2019, 53:1800736) on March 28, 2019.
Figure 1. Custom-built high-speed real-time intravital microscope platform
Figure 2. Illustrative schematic and photo of a 3D intravital lung microscopic imaging system
Figure 3. Aggregation of neutrophils and consequent flow disturbance in pulmonary arteriole in sepsis-induced lung injury
2019.05.07 View 43897 -
Research Day Highlights Most Outstanding Research Achievements
Professor Byung Jin Cho from the School of Electrical Engineering was selected as the Grand Research Prize Winner in recognition of his innovative research achievement in the fields of nano electric and flexible energy devices during the 2019 KAIST Research Day ceremony held on April 23 at the Chung Kunmo Conference Hall.
The ten most outstanding research achievements from the past year were also awarded in the three areas of Research, Innovation, Convergence Researches.
Professor Cho is an internationally recognized researcher in the field of future nano and energy device technology. Professor Cho’s team has continued to research on advanced CMOS (complementary metal-oxide semiconductors). CMOS has become his key research topic over the past three decades.
In 2014, he developed a glass fabric-based thermoelectric generator, which is extremely light and flexible and produces electricity from the heat of the human body. It is so flexible that the allowable bending radius of the generator is as low as 20 mm. There are no changes in performance even if the generator bends upward and downward for up to 120 cycles. His wearable thermoelectric generator was selected as one of the top ten most promising digital technologies by the Netexplo Forum in 2015.
He now is working on high-performance and ultra-flexible CMOS IC for biomedical applications, expanding his scope to thermal haptic technology in VR using graphene-CMOS hybrid integrated circuits; to self-powered wireless sensor nodes and self-powered ECG system using wearable thermoelectric generators .
In his special lecture at the ceremony, Professor Cho stressed the importance of collaboration in making scientific research and presented how he moved to future devices after focusing on scaling the devices.
“When I started the research on semiconductors, I focused on how to scale the device down as much as possible. For decades, we have conducted a number of procedures to produce tiny but efficient materials. Now we have shifted to develop flexible thermoelements and wearable devices,” said Professor Cho.
“We all thought the scaling down is the only way to create value-added technological breakthroughs. Now, the devices have been scaled down to 7nm and will go down to 5 nm soon. Over the past few years, I think we have gone through all the possible technological breakthroughs for reducing the size to 5nm. The semiconductor devices are made of more 1 billion transistors and go through 1,000 technological processes. So, there won’t be any possible way for a single genius to make a huge breakthrough. Without collaboration with others, it is nearly impossible to make any new technological breakthroughs.”
Professor Cho has published more than 240 papers in renowned academic journals and presented more than 300 papers at academic conferences. He has also registered approximately 50 patents in the field of semiconductor device technology.
The top ten research highlights of 2018 as follows:
- Rydberg-Atom Quantum Simulator Development by Professor Jaewook Ahn and Heung-Sun Sim from the Department of Physics
- From C-H to C-C Bonds at Room Temperature by Professor Mu-Hyun Baik from the Department of Chemistry
- The Role of Rodlike Counterions on the Interactions of DNAs by Professor Yong Woon Kim of the Graduate School of Nanoscience and Technology
- The Medal Preoptic Area Induces Hunting-Like Behaviors to Target Objects and Prey by Professor Daesoo Kim from the Department of Biological Sciences
- Identification of the Origin of Brain Tumors and New Therapeutic Strategy by Professor Jeong Ho Lee from the Graduate School of Medical Science and Engineering
- The Linear Frequency Conversion of Light at a Spatiotemporal Boundary by Professor Bumki Min from the Department of Mechanical Engineering
- An Industrial Grade Flexible Transparent Force Touch Sensor by Professor Jun-Bo Yoon from the School of Electrical Engineering
- The Detection and Clustering of Mixed-Type Defect Patterns in Wafer Bin Maps by Professor Heeyoung Kim from the Department of Industrial and Systems Engineering
- The Development of a Reconfigurable Spin-Based Logic Device by Professor Byong-Guk Park from the Department of Materials Science and Engineering
- The Development of a Miniaturized X-Ray Tube Based on Carbon Nanotube and Electronic Brachytherapy Device by Professor Sung Oh Cho from the Department of Nuclear and Quantum Engineering
Professor YongKeun Park from the Department of Physics and Professor In-Chel Park from the School of Electrical Engineering received the Research Award. For the Innovation Award, Professor Munchurl Kim from the School of Electrical Engineering was the recipient and the Convergence Research Awards was conferred to Professor Sung-Yool Choi from the School of Electrical Engineering, Professor Sung Gap Im from the Department of Chemical and Biomolecular Engineering, and Professor SangHee Park from the Department of Materials Science and Engineering during the ceremony.
For more on KAIST’s Top Research Achievements and Highlight of 2018, please refer to the attached below. click.
2019.04.25 View 14813 -
Professor Ji-Hyun Lee Awarded the Sasada Prize
Professor Ji-Hyun Lee from the Graduate School of Culture Technology was awarded the Sasada Prize during the 24th annual Conference of Computer-Aided Architectural Design Research in Asia (CAADRIA) held in Wellington, New Zealand on April 15.
The Sasada Award honors the late Professor Tsuyoshi Sasada (1941-2005), the former Professor of Osaka University and co-founder and fellow of CAADRIA. It is given to an individual who has contributed to the next generation of researchers and academics, to the wider profession and practice in computer-aided design and research, and has earned recognition in the academic community.
Professor Lee was recognized for her development of CAAD (Computer-Aided Architectural Design) through her research work on the land price precision system using case-based reasoning. Her research team proposed a model for estimating the average apartment price in an administrative district after collecting 40 variables from the six major Korean cities, excluding Seoul and Ulsan. Their follow-up studies showed the possibility of replacing existing experts’ predictions.
Professor Lee has been steadily researching for 20 years on case-based reasoning (CBR), a field of artificial intelligence, and has published more than 40 papers in the field of CBR. Meanwhile, the CAAD Future 2019 event will be held at KAIST in June.
2019.04.23 View 6106 -
True-meaning Wearable Displays: Self-powered, Washable and Wearable
(Video: The washing process of wearing display module) When we think about clothes, they are usually formed with textiles and have to be both wearable and washable for daily use; however, smart clothing has had a problem with its power sources and moisture permeability, which causes the devices to malfunction. This problem has now been overcome by a KAIST research team, who developed a textile-based wearable display module technology that is washable and does not require an external power source.
To ease out the problem of external power sources and enhance the practicability of wearable displays, Professor Kyung Cheol Choi from the School of Electrical Engineering and his team fabricated their wearing display modules on real textiles that integrated polymer solar cells (PSCs) with organic light emitting diodes (OLEDs).
PSCs have been one of the most promising candidates for a next-generation power source, especially for wearable and optoelectronic applications because they can provide stable power without an external power source, while OLEDs can be driven with milliwatts. However, the problem was that they are both very vulnerable to external moisture and oxygen. The encapsulation barrier is essential for their reliability. The conventional encapsulation barrier is sufficient for normal environments; however, it loses its characteristics in aqueous environments, such as water. It limits the commercialization of wearing displays that must operate even on rainy days or after washing.
To tackle this issue, the team employed a washable encapsulation barrier that can protect the device without losing its characteristics after washing through atomic layer deposition (ALD) and spin coating. With this encapsulation technology, the team confirmed that textile-based wearing display modules including PSCs, OLEDs, and the proposed encapsulation barrier exhibited little change in characteristics even after 20 washings with 10-minute cycles. Moreover, the encapsulated device operated stably with a low curvature radius of 3mm and boasted high reliability.
Finally, it exhibited no deterioration in properties over 30 days even after being subjected to both bending stress and washing. Since it uses a less stressful textile, compared to conventional wearable electronic devices that use traditional plastic substrates, this technology can accelerate the commercialization of wearing electronic devices. Importantly, this wearable electronic device in daily life can save energy through a self-powered system.
Professor Choi said, “I could say that this research realized a truly washable wearable electronic module in the sense that it uses daily wearable textiles instead of the plastic used in conventional wearable electronic devices. Saving energy with PSCs, it can be self-powered, using nature-friendly solar energy, and washed. I believe that it has paved the way for a ‘true-meaning wearable display’ that can be formed on textile, beyond the attachable form of wearable technology.”
This research, in collaboration with Professor Seok Ho Cho from Chonnam National University and led by Eun Gyo Jeong, was published in Energy and Environmental Science (10.1039/c8ee03271h) on January 18, 2019.
Figure 1. Schematic and photo of a washable wearing display module
Figure 2. Cover page of Energy and Environmental Science
2019.03.21 View 30791 -
Distinguished Professor Sang Yup Lee Honored with the 23rd NAEK Award
(Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering)
Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering was honored to be the laureate of the 23rd NAEK Award.
The NAEK (National Academy of Engineering of Korea) Award was instituted in 1997 to honor and recognize engineers who have made significant contributions to the development of the engineering and technology field at universities, industries, and institutions. Every year, it is conferred to only one person who has achieved original and world-leading research that has led to national development.
Distinguished Professor Lee is a pioneering scholar of the field of systems metabolic engineering and he was recognized for his significant achievements in the biochemical industry by developing novel microbial bioprocesses. In particular, he is globally renowned for biological plastic synthesis, making or decomposing polymers with microorganisms instead of using fossil resources.
He has produced numerous high-quality research breakthroughs in metabolic and systems engineering. In 2016, he produced an easily degradable plastic with Escherichia coli (E. coli). In 2018, he successfully produced aromatic polyesters, the main material for PET (poly ethylene terephthalate) from E. coli strains. He also identified microorganism structures for PET degradation and improved its degradability with a novel variant.
His research was ranked number one in the research and development division of Top Ten Science and Technology News 2018 announced by Korean Federation of Science & Technology Societies. He is one of highly cited researchers (HCR) ranked in the top 1% by citations for their field by the Clarivate Analytics.
2019.03.21 View 7655 -
The Future Mobility of the Year 2019
KAIST announced the Future Mobility of the Year (FMOTY) 2019. The winners are Volvo 360C, Toyota e-Palette, and Toyota Concept-i WALK.
FMOTY are the first awards that recognizes concept cars that exhibit innovative services and practical transportation technology in three categories: private mobility, public and commercial mobility, and personal mobility.
Figure 1. The winner in the private mobility division, the Volvo 360C
In the private mobility division, the award went to the Volvo 360C. With targeted routes of roughly 186 miles, this vehicle has an ambitious service goal to replace airplanes by traveling these routes with great comfort. Goro Okazaki, a journalist with Car and Driver Japan, said, “The Volvo 360C clearly shows how highly personalized autonomous driving can change the future.”
Figure 2. The winner in the public mobility division, the Toyota e-Palette
The Toyota e-Palette was the winning car in commercial mobility division. This vehicle provides the best solution as a mobile service platform by transforming itself into mobile hospitals, hotels, stores and food trucks. Carlo Calderón, a journalist for Autopista Spain, said, “It has a great strength in remodeling its indoor and outdoor spaces according to various commercial uses.”
Figure 3. The winner in the personal mobility division, the Toyota Concept-i WALK
In the personal mobility division, the award went to the Toyota Concept-i WALK. It was recognized for having an exquisite user environment and artificial intelligent agent, along with an excellent completion. Jun Miao, a journalist with MJ CarShow China, said, “It is aesthetically pleasing. Beyond the upright control of conventional personal mobility, it allows agile control with a joystick.”
FMOTY conducted a screening process for 45 concept cars over three months and 16 renowned automotive experts from 11 countries participated as judges for this award, including Editor in Chief of BBC Top Gear Magazine Charlie Turner and European Bureau Chief of Automobile Magazine Georg Kacher. The judges said that FMOTY was born to propose a new aspect of future mobility, and in terms of evaluating technical and social values of concept cars, FMOTY carries great significance.
Kyung-soo Kim, Dean of the Cho Chun Shik Graduate School of Green Transportation said, “Globally renowned experts in the automotive field participated as judges to elevate the prestige and fairness of the awards. KAIST members were excluded from the entire judging process. I believe that the FMOTY Awards will expand public attention from the present to the future.”
Details can be found on the official website of FMOTY ( www.fmoty.org ).
2019.03.11 View 6340