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The 8th International Conference on Metabolic Engineering was held on June 13-18, 2010 in Jeju Island, South Korea.
From left to right, top row: Distinguished Professor and the conference chair Sang Yup Lee, Sang-Hyup Kim - Secretary to the President of Korea, Dr. Jay Keasling, Dr. Greg Stephanopoulos. Left to right, bottom row: Dr. William Provine, Dr. Terry Papoutsakis, Dr, Jens Nielsen, Dr. Lars Nielsen. The importance of industrial biotechnology that produces chemicals and materials from renewable biomass is increasing due to climate change and the dearth of natural resources. Industrial biotechnology refers to a technology that allows sustainable bio-based production of chemicals and materials that could enrich human"s lives using microorganisms. This is where metabolic engineering comes into play for successful application of microorganisms, in which they are engineered in our intended way for improved production capability. The 8th International Conference on Metabolic Engineering, the longest running conference of its kind, was held on June 13-18, 2010 at the International Convention Center in Jeju Island, South Korea. Distinguished Professor Sang Yup Lee of KAIST, Dean of College of Life Science and Bioengineering and Co-Director of Institute for the BioCentury, chaired the conference with the main theme of "metabolic engineering for green growth." With 300 delegates selected by the committee, papers on production of biofuels, chemicals, biopolymers, and pharmaceutics and the development of fundamental metabolic engineering techniques were presented at the conference along with examples of successful commercialization of products developed by several global companies. Sang Hyup Kim, Secretary to the President of Korea, gave an opening plenary lecture entitled "Korean green growth initiative," to inform experts from around the globe of the leadership on green growth in Korea. Young Hoon Park, President of Korea Research Institute of Bioscience and Biotechnology (KRIBB, Korea) delivered his congratulatory address. Sang Hyup Kim said, "Hosting an international conference in Korea on metabolic engineering, which forms a core technology necessary for the development of environmentally friendly processes for producing chemicals and biofuels from renewable biomass, is very meaningful as green growth is a big issue around the globe. This is a great chance to show the excellence of Korea"s green growth associated technology to experts in metabolic engineering and industrial biotechnology." A total of 47 invited lectures in this conference included recent and important topics, for instance, "Synthetic biology for synthetic fuels" by Dr. Jay Keasling from the Joint BioEnergy Institute (USA), "Microbial oil production from renewable feedstocks" by Dr. Greg Stephanopoulos from MIT (USA), "Yeast as a platform cell factory for production of fuels and chemicals" by Dr. Jens Nielsen from Chalmers University (Sweden), "Mammalian synthetic biology - from tools to therapies" by Dr. Martin Fussengger from ETH (Switzerland), "Building, modeling, and applications of metabolic and transcriptional regulatory networks at a genome-scale" by Dr. Bernhard Palsson from the University of California - San Diego (USA), "Genome analysis and engineering Eschericha coli for sucrose utilization" by Dr. Lars Nielsen from the University of Queensland (Australia), "Artificial microorganisms by synthetic biology" by Dr. Daniel Gibson from JCVI (USA), and "Metabolomics and its applications" by Dr. Masaru Tomita from Keio University (Japan). From Korea, Dr. Jin Hwan Park from the research group of Dr. Sang Yup Lee at KAIST presented "Systems metabolic engineering of Escherichia coli for amino acid production," and Dr. Ji Hyun Kim from KRIBB presented "Genome sequencing and omics systems analysis of the protein cell factory of Escherichia coli". Global companies involved in biorefinery presented their recent research outcomes with emphasis on commercialized technologies. They included "Metabolic and process engineering for commercial outcomes" by Dr. William Provine from DuPont (USA), "Direct production of 1,4-butanediol from renewable feedstocks" by Dr. Mark Burk from Genomatica (USA), "Development of an economically sustainable bioprocess for the production of bio 1,2-propanediol" by Dr. Francis Voelker from Metabolic Explorer (France), "Biotechnology to the bottom-line: low pH lactic acid production at industrial scale" by Dr. Pirkko Suominen from Cargill (USA), "Bioisoprene™: traditional monomer, traditional chemistry, sustainable source" by Dr. Gregg Whited from Danisco (USA) and "Efficient production of pharmaceuticals by engineered fungi" by Dr. Roel Bovenberg from DSM (Netherlands). This biennial conference also presented the International Metabolic Engineering Award (expanded version of the previous Merck Metabolic Engineering Award) to the best metabolic engineer in the world. The 2010 International Metabolic Engineering Award went to Dr. E. Terry Papoutsakis from the University of Delaware (USA) who has contributed to the production of biobutanol through the metabolic engineering of Clostridia in the last three decades, and he gave an award lecture. Dr. Sang Yup Lee, the current chair of the upcoming conference, was the previous recipient of this award at the last metabolic engineering conference in 2008. In addition to the invited lectures, a total of 156 carefully selected poster papers were chosen for presentation, and awards were presented to the best posters after rigorous review by the committee members. Such awards included "The 2010 Metabolic Engineering Best Poster Award" and the "2010 Young Metabolic Engineer Award" from the Metabolic Engineering conference, and prestigious international journal awards, including "Wiley Biotechnology Journal Best Poster Award", "Wiley Biotechnology and Bioengineering Best Poster Award" and "Elsevier Metabolic Engineering Best Paper Award." Dr. Catherine Goodman, a senior editor of Nature Chemical Biology, also presented the "Nature Chemical Biology Best Poster Award on Metabolic Engineering." Regarding this conference, Dr. Sang Yup Lee, the conference chair, said, "This conference is the best international conference in the field of metabolic engineering, which is held every two years, and Korea is the first Asian country to host it. All the experts and students spend time together from early breakfast to late poster sessions, which is a distinct feature of this conference. Although the number of delegates had typically been limited to 200, around 300 delegates were selected this year to accept more attendees from many people who have been interested in metabolic engineering. Also, it is very fitting that "green growth" is the main topic of this conference because Korea is playing a key role in this field. I"m grateful to the Lotte Scholarship Foundation, COFCO, GS Caltex, Bioneer, US DOE, US NSF, Daesang, CJ Cheiljedang, Genomatica and DuPont who provided us with generous financial support that allowed the successful organization of this conference." The conference was organized by the Systems Biology Research Project Team supported by the Ministry of Eduction, Science and Technology (MEST), Microbial Frontier Research Project Group, World Class University Project Group at KAIST, Institute for the BioCentury at KAIST, Korean Society for Biotechnology and Bioengineering, and the Engineering Conference International (ECI) of the United States. Inquiries: Professor Sang Yup Lee (+82-42-350-3930), industrialbio@gmail.com
2010.06.25
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President Suh Hosted Press Conference with Seoul-based Correspondents, on March 9, 2010
President Suh Hosted Press Conference with Seoul-based Correspondents, on March 9, 2010 President Nam-Pyo Shu had a press conference with foreign correspondents based in Seoul, South Korea, on March 9, 2010 at Seoul Foreign Correspondents’ Club (SFCC). Prior to the conference, the president and correspondents attended a ceremony for the completion of Online Electric Vehicles (OLEV) that carries passengers to look around the amusement park, Seoul Grand Park, in Gewacheon City. OLEV was developed and built by KAIST. Following President Suh’s opening speech, a questions and answers (Q&A) session between the president and reporters proceeded. In his opening speech, President Suh said electric vehicles are an alternative to conventional automobiles with combustion engines, and in order to manufacture affordably priced electric vehicles on a large scale, their charging should be streamlined. In response, KAIST has come up with the online electric vehicle concept. He added, without installing separate charging stations, OLEV receives electric power from the cables buried underground while driving, idling, or parking. Its connection to a power source is non-contact. President Suh expressed his excitement for demonstrating OLEV at Seoul Grand Park that its system works as KAIST has designed and predicted. He showed his confidence that KAIST is indeed at the stage to implement OLEV in Seoul City soon and hoped to demonstrate it at the upcoming G-20 Summit to be held in November 2010 in Seoul City. During the Q&A session, reporters cited the construction of OLEV at the amusement park and mainly asked about a possibility of its commercialization. Other topics, they also questioned about, were hurdles related to the development and commercialization of OLEV; level of cooperation received from industries and central/local governments; technological breakthroughs and accomplishments; future development plans for the commercialization; and reactions from the public and government. Media outlets participated in the conference were Reuters, AFP, the International Herald Tribune, ABC News, Bloomberg News, Businessweek, Voice of America, Sankei Shimbun, and etc.
2010.03.16
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A Breakthrough for Cardiac Monitoring: Portable Smart Patch Makes It Possible for Real-time Observation of Heart Movement
Newly invented device makes the monitoring easier and convenient. Professor Hoi-Jun Yoo of KAIST, Department of Electrical Engineering, said that his research team has invented a smart patch for cardiac monitoring, the first of its kind in the world. Adhesive and can be applied directly to chest in human body, the patch is embedded with a built-in high performance semiconductor integrated circuit (IC), called Healthcare IC, and with twenty five electrodes formed on the patch’s surface. The 25-electrodes, with a capability of creating various configurations, can detect cardiac contractions and relaxations and collect electrocardiogram (ECG) signals. The Healthcare IC monitors ECG signals and sends the information to a portable data terminal like mobile phones, making it possible for a convenient, easy check up on cardiac observations. The key technologies used for the patch are the Healthcare IC that measures cardiovascular impedance and ECG signals, and the electronic circuit board made of four layers of fabric, between which electrodes, wireless antenna, circuit board, and flexible battery are installed. With the P-FCB (Planar Fashionable Circuit Board) technology, the research team explained, electrodes and a circuit board are directly stacked into the fabric. Additionally, the Healthcare IC (size: 5mm x 5mm), which has components of electrode control unit, ECG and cardiovascular resistance detection unit, data compression unit, Static Random Access Memory (SRAM), and wireless transmitter receiver, is attached on the fabric. The Healthcare IC is operated by an ultra-low electrical power. Like a medicated patch commonly used to relieve arthritis pains, the surface of smart patch is adhesive so that people can carry it around without much hassle. A finished product will be 15cm x 15 cm in size and 1mm high in thickness. The Healthcare IC can measure cardiovascular impedance variances with less than 0.81% distortion in 16 different configurations through differential current injectors and reconfigurable high sensitivity detection circuitry. “The patch will be ideal for patients who suffer a chronic heart disease and need to receive a continuous care for their condition. Once commercialized, the patch will allow the patients to conduct a self-diagnosis at anytime and anywhere,” said Yan Long, a member of the research team. There has been a continuously growing demand worldwide since 2000 for the development of technology that provides a suitable healthcare management to patients with a chronic heart disease (e.g., cardiovascular problems), but most of the technology developed today are only limited to monitoring electrical signals of heart activity. Cardiovascular monitors, commonly used at many of healthcare places nowadays, are too bulky to use and give uncomfortable feelings to patients when applied. Besides, the current monitors are connected to an electrical line for power supply, and they are unable to have a low power communication with an outdoor communication gadget, thus unavailable for wide use. Professor Yoo gave his presentation on this new invention at an international conference, International Solid-State Circuits Conference, held on February 8-10 in San Francisco. The subject of his presentation was “A 3.9mW 25-electorde Reconfigurable Thoracic Impedance/ECG SoC with Body-Channel Transponder.” (Picture 1) Structure of Smart Patch (Picture 2) Smart patch when applied onto human body (Picture 3) Data received from smart patch (Picture 4) Healthcare IC
2010.02.17
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Indoor Localization System for Mobile Devices Developed by KAIST Research Team
The technology will be available to smart phone users around the world through Goole Apps Store. The wireless fidelity (WiFi)-based indoor localization can be installed on smart phones for commercialization, a technology developed by a research team at KAIST. The KAIST research team, led by Professor Dong-Soo Han, Department of Computer Science and Engineering, explained that the technology offers smart phone users, e.g., Google’s Android phone and Apple’ iPhone, a unique way to recognize their location through WiFi Open Radio Map. WiFi Open Radio Map is built with WiFi Location Fingerprint that contains wireless local area network (LAN)’s signal strength and wireless access points (AP) number, and with location information. Through using the Map, WiFi-based indoor localization recognizes the location of smart phones and sends the location information to the phones. Since the technology uses WiFi signal information only to recognize the whereabouts of phones, it can be widely used in the future, without installing extra machines and equipment for detection, for a complicated, large indoor environment, where the Global Positioning System (GPS) is not available. Currently, Professor Han has established WiFi Open Radio Map inside and outside of a few buildings at KAIST and developed several location based application services to perform a beta testing. He plans to open and distribute the technology to smart phone users through Google and Apple Apps Store in early 2010. Collaborations with major smart phone makers such as SK Telecom, Korea Telecom, and Samsung as well as outdoor/indoor localization manufactures and suppliers will also be sought, according to Professor Han. Professor Han is invited to an international conference, Eighth Annual IEEE International Conference on Pervasive Computing and Communications, slated for early April 2010, in recognition of his work. At the conference, he will give a presentation on WiFi based indoor localization technology and conduct its demo version.
2010.02.10
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KAIST to Host ITTP Conference in Tunisia
KAIST"s Global IT Technology Program (ITTP) will host an international conference at Hammamet Hotel in Tunisia in cooperation with its counterpart at Seoul National University (SNU) on Nov. 23, university authorities said on Wednesday (Nov. 18). The event is a pre-conference for the ICT4All Forum on Nov. 24-25 which the Tunisian government is organizing with the ADB, World Bank, Arab Society for Intellectual Property and the UTICA to deal with developing information and communication technologies. KAIST"s ITTP which started in 2006 is designed to build global network of IT leaders around the world. The program supported by the Korean Ministry of Knowledge and Economy offers a customized master"s and doctoral degree program for foreign government officials, employees of public institutions and senior researchers at national research centers working in the IT fields. Scholarships are provided for all trainees, for up to 2 years for master"s students and up to 3 years for doctoral students. The program focuses on transferring advanced technologies and business strategies of Korea to the global IT leaders of the next generation. During the conference, seven government officials from as many countries currently under the KAIST or SNU programs will present international cooperation cases based on their own experiences in the IT fields. KAIST ITTP organizers will also provide an educational session on the mobile government for Tunisian experts and conference participants in the information and communications fields.
2009.11.20
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KAIST Undergraduates Open Four-Day International Conference
The ICISTS-KAIST, an annual international conference organized by KAIST undergraduate students, opened on Thursday (Aug. 20) at the KAIST"s main campus in Daejeon. The 2009 ICISTS (International Conference for the Integration of Science and Technology into Society) drew around 200 experts and students from 44 countries. Since its inception in 2005 to promote discourse on important science and technology issues affecting modern society, the conference has served as an opportunity for academic networking among students in various parts of the world. The four-day conference consists of lectures, open discussions among lecturers and students, field trips to help students to understand actual applications, and team projects. This year"s conference offers three workshops under the themes of "Climate Change: Merging Technology and Policy for Green Solutions"; "Human-Computer Interaction: Designing Computer System for Intuitive Human Access"; and "Nano Clinic: Breakthrough in Conquering Disease." Lectures by invited experts in various scientific fields will help broaden students" perspectives particularly from interdisciplinary viewpoints, said an organizer of the conference.
2009.08.28
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KAIST Professor Sang-Yup Lee Chair of International Metabolic Engineering Conference Due Next Year
KAIST distinguished professor Sang-Yup Lee was named to chair the 17th Metabolic Engineering Conference which will convene on Jeju Island, Korea, next year, under the theme of "Metabolic Engineering for Green Growth." It was decided at the 16th Biochemical Engineering Conference held in Burlington, Vermont, on July 5-9. Metabolic Engineering Conference in 2010 will not only involve presentations and discussions about metabolic engineering, but will inaugurate the “World Council on Industrial Biotechnology,” which will bring together global corporations and the world’s experts in industrial biochemical engineering, according to sources at KAIST. A KAIST official commented, “The fact that the Metabolic Engineering Conference is to be held here [in Korea] proves that Korea is being acknowledged as a key player in this field.” As the world faces the depletion of fossil fuels and environmental pollution, nations are showing increasing interest in industrial biochemical alternatives, such as microscopic organisms or new chemicals, to solve their problems. In addition, efficient production of biochemical materials and bio-fuels using microbes is deemed vital for the future. “The Korean government has become a model to other countries thanks to its leadership in carrying out the ‘Green Growth’ policy,” Professor Sang-Yup Lee said. He stated that KAIST is recognized for its research in advanced biochemical material and fuel production methods. “Green Growth,” a concept first developed by ESCAP, the UN agency working for social and economic cooperation in Asia and the Pacific, aims to achieve sustainable economic growth without destroying the environment. Ref. Department of Biochemical Engineering, Metabolic and BioMolecular Engineering Lab, KAIST
2009.07.17
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Prof. Chong Unveils New Human Movement Model
A KAIST research team headed by Prof. Song Chong of the School of Electrical Engineering and Computer Science has developed a new statistical model that simulates human mobility patterns, mimicking the way people move over the course of a day, a month or longer, university sources said on Tuesday (May 12). The model, developed in collaboration with scientists at North Carolina State University, is the first to represent the regular movement patterns of humans using statistical data. The model has a variety of potential uses, ranging from land use planning to public health studies on epidemic disease. The researchers gave global positioning system (GPS) devices to approximately 100 volunteers at five locations in the U.S. and South Korea and tracked the participants" movements over time. By tracing the points where the study participants stopped, and their movement trajectories, researchers were able to determine patterns of mobility behavior. The researchers were then able to emulate these fundamental statistical properties of human mobility into a model that could be used to represent the regular daily movement of humans. The model, called Self-similar Least Action Walk (SLAW), will have a wide array of practical applications. The research, "SLAW: A Mobility Model for Human Walks," was presented on April 20 at the 28th IEEE Conference on Computer Communications in Rio de Janeiro, Brazil. The National Science Foundation of the U.S. funded the research.
2009.05.13
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2008 IEEE International Conference on Humanoid Robots Opens
The 2008 IEEE-RAS International Conference on Humanoid Robots, an international gathering to identify new research trends and technology in humanoid robotics, will open a three-day session on Monday (Dec. 1) at the Hotel Rivera and KAIST in Daejeon. The annual conference is organized by KAIST and the Robotics and Automation Society of the Institute for Electric and Electronic Engineers, a U.S.-based international non-profit, professional organization for the advancement of technology related to electricity. The conference is expected to draw a total of 200 robotics researchers from 19 different countries. Prof. Jun-Ho Oh, at the Department of Mechanical Engineering who led the creation of Korea"s first humanoid robot Hubo, is serving as general chair of the conference. Prof. Oh was named the host of the 2008 conference at the 2007 conference held at the Carnegie Melon University of the United States. The eight-year old conference was inaugurated in Boston in 2000. On the opening day of Dec. 1, seven lectures will be given on diverse areas of robotics including cognitive humanoid vision, and robot vision sensor and sensing. On the subsequent two days, a total of 110 papers will be presented. During the conference period, a variety of robots produced by six local and foreign robot makers will be on demonstration, providing opportunities for researchers and industrial robot makers to share technological ideas. Highlights of the conference will be special lectures by world-renowned robot researchers Prof. Yoshiyuki Sankai of University of Tsukuba, who has created an exoskeletal "robot suit," and Prof. Art Kuo of Univerity of Michigan who is regarded as a leading authority in dynamic walking. Following the conference, all participants are scheduled to tour Prof. Oh"s Hubo Lab and the Human-Robot Interaction Research Center, both located at KAIST.
2008.12.01
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Int'l Conference for Integration of Science & Technology into Society Opens
The 2008 International Conference for the Integration of Science and Technology into Society (ICISTS-KAIST) opened a four-day meeting on Tuesday (July 15) at Daejeon KAIST campus. The conference is an annual event organized by a group of KAIST undergraduate students. The fifth-year gathering is designed to provide participants with an opportunity to broaden their scientific perspectives by sharing ideas and experiences in related topics, as well as building an international human network. This year"s event has drawn about 200 students from 40 countries. The centerpiece of the conference is three workshops on the following themes; Human-Robot Symbiotic Society, Neo-brain Science and Trafficmatics. Myung-Ja Kim, former Korean Environment Minister, will appear as a keynote speaker. In the workshop sessions, two speakers will discuss specific issues and arrive at a tentative conclusion. Participants will have the opportunity to participate in the debate through Q&A for each session. The first theme "Human-Robot Symbiotic Society" delves into the current trend that robot is being transformed into a perceivable and touchable concept from an abstract one. Guests for the workship include June-Ho Oh, professor at the Department of Mechanical Engineering, KAIST; James Dater, professor at the Department of Political Science, University of Hawaii at Manoa, and Director of the Hawaii Research Center for Future; Michael Pollitt, CEO of Shadow Robot Company; and Steven Dubowsky, professor at the Department of Mechanical Engineering, MIT. The second theme "Neo-Brain Science" focuses on attempts to shed light on brain from diverse perspectives including psychology, economics and art. Among invited speakers are Prof. Jai-Seung Jung at the Department of Bio and Brain Engineering, KAIST; Prof. Un-Jung Kang at the University of Chicago Medical Center; and Peter Geyer, a consultant for the Association for Psychological Type. The third workshop on "Traffimatics" will deal with "intelligent transport systems (ITS)" which will discusst new paradigm in transportation policy and traffic engineering. On the list of speakers are Assaf Biderman, assistant director, SENSEable City Laboratory, MIT; Prof. Richard Tay, at the Department of Civil Engineering, University of Calgary; Prof. Shoshi Mizokami at Kumamoto University; and Ho-Jong Baik, research associate professor of Virginia Tech.
2008.07.16
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Ki-Won Lee Receives Best Student Paper Award
Ki-Won Lee Receives Best Student Paper Award Ki-Won Lee, a doctoral student of Materials Science & Engineering, has received the Best Student Paper Award ‘Motorola Fellowship Award’ at 2007 Electronic Components and Technology Conference (ECTC). Lee’s paper is about a new bonding process of anisotropic conductive film using ultrasonic wave, which applies ultrasonic wave, instead of thermal compression, at the room temperature to reduce the process time from ten to three seconds. The recipients of Motorola Fellowship Award are selected by IEEE Components, Packaging and Manufacturing Technology Society, and Motorola awards special scholarship to recipients. The ECTC is the world’s largest yearly conference concerning electronic packaging technologies with more than 1,000 attendees and more than 300 presented papers.
2007.07.02
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KAIST president R. Laughlin speaks during a news conference
KAIST president Robert Laughlin speaks during a news conference at the Government Complex in Kwachon, south of Seoul, Tuesday. / Korea Times 2005-02-01 THE KOREA TIMES By Kim Tae-gyuStaff Reporter Robert Laughlin, president of Korea Advanced Institute of Science and Technology (KAIST), takes a step backward from his hardline push for KAIST reform in the face of strong opposition. The 1998 Nobel laureate in physics, who took the helm of the nation’s top technology university last July, made the point Tuesday at a press conference at the Kwachon Government Complex in southern Seoul. ``Privatization of KAIST is not on the table. We are only discussing securing money for the advancement of KAIST as a world-class institution,’’ the 54-year-old president said. Laughlin also denied the swirling suspicions that he plans to transform KAIST to a general-purpose, undergraduate-focused college from the current research-oriented graduate school. ``The issue we are discussing is moving the business model of KAIST toward the one used by the Massachusetts Institute of Technology, not changing KAIST’s structure,’’ he said. This is a retreat from his original plan to fundamentally overhaul the state-funded KAIST to a market-oriented institute by several aggressive measures. In a new investment strategy for KAIST in December, roughly five months after his tenure began, Laughlin said KAIST is trapped in a funding squeeze from which there appears to be no exit. He then suggested revamping its traditional emphasis on graduate education because this type of system has come to be out of tune with the market. He even proposed expanding the enrollment of KAIST to 20,000 from the current total of 7,500 and charging tuition fees of 3 million won per semester from the current fee of under 850,000 won. The surprise reform plan created a backlash from KAIST faculty, students and government officials, who regarded the scheme as a privatization attempt. In the process, professor Park O-ok, dean of the school’s planning office, resigned from his position in early December and asked Laughlin to abandon the reform. In response, Laughlin said the miscommunication resulted from the secret process of KAIST reform discussion. He expected policy announcement in early March to clear up misconceptions. Regarding Park’s protests, he said: ``I had a personality problem with him but that has now been fixed.’’ Yesterday, Laughlin appointed Chang Soon-heung, professor in the Department of Nuclear and Quantum Engineering, to fill Park’s position. voc200@koreatimes.co.kr
2005.02.02
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