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Professor Min Hyuk Kim Appointed an Associate Editor on ACM Transactions on Graphics
Professor Min Hyuk Kim of KAIST's Computer Science Department has been appointed an associate editor for a prestigious international journal in the field of graphics, ACM Transactions on Graphics (TOG).
Founded in 1947, the Association for Computing Machinery (ACM) is the world’s largest educational and scientific computing society, delivering knowledge that advances computing as a science and profession.
Published during the past 35 years, ACM TOG is a highly regarded, peer-reviewed scientific journal that aims to disseminate the latest findings of research in computer graphics. Professor Kim is the first Korean scholar to serve the journal as an editor.
Professor Kim’s responsibilities are many, and they include selecting appropriate reviewers for submitted manuscripts to be published in the journal and reporting the results of review process.
He said, “The appointment was a great honor, and I’m looking forward to having the opportunity to make further contributions to the advancement of the graphics field.”
Professor Kim has published numerous papers on computer graphics with a focus on research in 3D imaging spectroscopy and visual perception.
2014.07.14 View 9219 -
Artificial Antibody-based Therapeutic Candidate for Lung Cancer Developed
Professor Hak-Sung Kim of Biological Sciences at KAIST publishes a cover article on artificial antibody in "Molecular Therapy".
Repebody-based lung cancer therapeutic drug candidate developed Repebody-based protein demonstrates the possibility of the development of a new drug
KAIST Biological Sciences Department’s Professor Hak-Sung Kim, in collaboration with Professor Eun-Kyung Cho from the College of Medicine at Chungnam National University, has successfully developed an artificial antibody-based, or repebody, cancer therapeutic candidate. These research results were published as a cover paper of the July edition of Molecular Therapy.
The repebody developed by Professor Kim and his team strongly binds to interleukin-6, a cancer-causing factor. It has also been confirmed that the repebody can significantly inhibit the proliferation of cancer cells in non-small-cell lung cancer animal model.
Numerous multinational pharmaceutical and biotechnology companies have invested astronomical amounts of money in research for the development of protein therapeutics with low side effects and high efficacy. More than 20 kinds of such therapeutics are currently under clinical trials, and over 100 drugs are under clinical demonstration. Among these, the majority is antibody-based therapeutics, and most of the investments are heavily concentrated in this field. However, antibody production cost is very high because it has large molecular weights and complex structural properties, and this makes it difficult to engineer. Consequently, the development costs a great deal of time and money.
In order to overcome the existing limitations of antibody-based therapeutics, Professor Kim and his team have developed a new artificial antibody, or repebody, which was published in Proceedings of the National Academy of Sciences (PNAS) in 2012. Based on this research, they have succeeded in developing a therapeutic candidate for treating non-small-cell lung cancer with a specifically strong cohesion to the cancer-causing factor, interleukin-6.
Interleukin-6 is a crucial substance within the body that is involved in immune and inflammatory-related signals. When abnormally expressed, it activates various carcinogenic pathways and promotes tumor growth and metastasis. Because of its importance, multinational pharmaceutical companies are heavily investing in developing therapeutics that can inhibit the signaling of interleukin-6.
In this study, Professor Kim and his team observed that a repebody consists of repeated modules, and they conceived a module-based affinity amplification technology that can effectively increase the binding affinity with the disease target. The developed therapeutic candidate has been confirmed in cell and animal experiments to show low immunogenicity, as well as to strongly inhibit the proliferation of non-small-cell lung cancer.
Furthermore, by investigating the complex structure of the repebody with interleukin-6, Professor Kim has identified its mechanism, which demonstrated the potential for therapeutic development. The researchers are currently carrying out pre-clinical trials for acquiring permission to perform clinical trials on animals with non-small-cell lung cancer. The repebody can be developed into a new protein drug after demonstrating its safety and efficacy.
Professor Hak-Sung Kim and his team have confirmed that the repebody can be utilized as a new protein drug, and this will be a significant contribution to Korea’s protein drugs and biotechnology industry development.
The research was supported by the Future Pioneer Industry project and sponsored by the Ministry of Science, ICT and Future Planning.
Figure 1. Professor Kim’s article published as the cover article of July edition of Molecular Therapy
Figure 2. Clinical proof of the repebody’s inhibition of cancer growth using animal models
2014.07.14 View 12102 -
Opening of "Education Donation Center" for Knowledge Sharing
KAIST is a leader in knowledge-sharing services for the educationally underprivileged. KAIST held the opening ceremony of the Education Donation Center at its Munji Campus on July 4, 2014 and was appointed as a “2014 Chungcheong-Gangwon province model local education donation center” sponsored by the Education Ministry of Korea and Korea Foundation for the Advancement of Science and Creativity.
The Education Donation Center (EDC) will integrate programs run by the Chungcheong-Gangwon province education donation organizations and introduce them to local chapter organizations. The EDC will recommend new donation organizations to the organizations in need. To ensure efficient donation, the EDC will consult programs of donation organizations. The EDC will also suggest regionally suitable education donation programs. KAIST will provide three staff members, six graduate students, and one to manage the career counselor to the center.
Joo-Sung Lee of the Business & Technology Management Department is the professor in charge of the EDC. He explained, “The center is the medium between the newly participating education donation organizations and the demand organizations. I will invest every effort to provide high-quality educational benefits to educationally underprivileged people."
KAIST has also been running an education service group called ‘Midam Scholarship’, an online education donation group called ‘Chalk’, and science camp programs for youth to establish the sharing and collaboration culture of KAIST.
2014.07.10 View 8074 -
The ICISTS-KAIST International Conference from August 4-8, 2014 in KAIST Campus, Korea
"Does science lead progress?"
This thought-provoking question will be explored this summer with hundreds of university students gathered from all around the world at the campus of the Korea Advanced Institute of Science and Technology (KAIST), a leading science and technology university in Korea.
Established in 2005, the International Conference for Integration of Science, Technology and Society (ICISTS)-KAIST has been hosted every summer for Korean and international university students in Daejeon, Republic of Korea. The conference features distinguished speakers from academia, business, and public sectors and enables participants to exchange views, identify issues affecting science and society, and explore possible solutions.
The ICISTS-KAIST is the largest interdisciplinary conference in Asia. It is organized by undergraduate students of KAIST and promotes the idea of a science- and technology-integrated society through international cooperation of college students from diverse backgrounds. Last year alone, about 400 participants from 103 universities in 25 countries attended the conference.
Marking the 10th anniversary, the ICISTS-KAIST International Conference 2014 will scrutinize the fundamental aspect of scientific and technological progress versus social advancement under the theme of "Does Science Lead Progress?"
"We hope that the conference provides students with an interactive platform to look into some of the essential, yet easily neglected, questions such as the purpose of science and technology education in a broader context of social values," said Dong-Yeon Woo, President of Organizing Committee for the ICISTS-KAIST International Conference 2014.
Among keynote speakers are Langdon Winner, a professor of Science and Technology Studies at Rensselaer Polytechnic Institute, Stephen Hilgartner, an associate professor of Science and Technology Studies at Cornell University, and Steve Breyman, an associate professor of Science and Technology Studies at Rensselaer Polytechnic Institute.
Langdon Winner will speak about the fallacy of the public perception that technological innovation leads to social revolution (his presentation is entitled "The Myth of Innovation"). Stephen Hilgartner will present four aspects of the politics of vision in today's science and technology ("Science, Technology, and the Politics of Vision"), and Steve Breyman will talk about the origin of scientific deception, misrepresentation, and prevarication ("The Agnotology of Hydrofracking").
The conference lasts five days, beginning on August 4th through August 8th, 2014 at KAIST campus. For participation, regular online application opens until July 11, 2014 at http://www.icists.org.
2014.07.04 View 9186 -
Professor Haeng-Ki Lee appointed as "ICCES Distinguished Fellow"
Professor Haeng-Ki Lee
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering at KAIST has been appointed as “Distinguished Fellow” and has also received the “Outstanding Research Award” at the International Conference on Computational & Experimental Engineering and Sciences (ICCES).
Founded in 1986, ICCES is regarded as one of the most prestigious international conferences in the field of computational mechanics and experimental engineering.
The Nominating Committee at ICCES recommends the appointment of a distinguished member who has made significant contributions to the development of computational mechanics and experimental engineering. Professor Lee was the first Korean who received such title. Furthermore, he was the recipient of the “Outstanding Research Award” presented by ICCES for his academic research on damage mechanics of complex systems.
Professor Lee is currently serving as the Head of the Department of Civil and Environmental Engineering at KAIST and the Director of BK Plus Agency, a Korean government’s research program. He received an award from the Minister of Science, ICT and Future Planning in 2013 for the promotion of science and technology.
2014.07.02 View 10284 -
JEROS, a jellyfish exterminating robot, appears in a US business and technology news
Business Insider, a US business and technology news website launched in 2006 and based in New York City, published a story about JEROS, a robot that disposes of ever-increasing jellyfish in the ocean.
JEROS was the brainchild of Professor Hyun Myung at the Department of Civil and Environmental Engineering, KAIST. It can shred almost one tons worth of jellyfish per hour.
For the story, please visit the following link:
Business Insider, June 24, 2014
“These Jellyfish-Killing Robots Could Save the Fishing Industry Billions Per Year”
http://www.businessinsider.com/jellyfish-killing-robot-2014-6
JEROS in action
2014.06.26 View 8331 -
Forbes Asia: 48 Heroes of Philanthropy
Mun-Sul Jeong
Hui-Jeong Park
Forbes Asia, an American business magazine covering the latest news on Asian markets, politics, business, and finance, announced the list of 48 philanthropists in the Asia-Pacific region in its July 21, 2014 issue.
Four Koreans made the list: Mun-Sul Jeong (a former chairman of KAIST's Board of Trustees), Hui-Jeong Park (a wife of the late Dr. Geun-Chul Ryu, a philanthropist who gave the funds to build the Sports Complex in KAIST campus), Yuna Kim (a former Olympics figure skater and a gold and silver medalist), and Nam-Kyu Min (the chairman of JK Group, a plastics and petrochemical products manufacturer).
Mun-Sul Jeong, the founder of Mirae Corp., a semiconductor equipment manufacturing company, donated $21 million to KAIST for brain science research this year. He also donated $235 million to KAIST in 2001 for convergence research in information and business technology.
Hui-Jeong Park, a former professor of nursing at Korea University, endowed a $100,000 scholarship fund for KAIST students in January 2014. Her late husband, Dr. Geun-Chul Ryu, contributed over $55 million in real estate to KAIST, allowing the university to have a new sports facility. He was an eminent doctor of Oriental medicine in Korea and also served as a professor at KAIST.
For more, please click on the link below:
Forbes Asia, July 21, 2014
“48 Heroes of Philanthropy”
http://www.forbes.com/sites/johnkoppisch/2014/06/25/48-heroes-of-philanthropy-3/
2014.06.26 View 8726 -
A KAIST startup, YBrain, builds a wearable device to cure Alzheimer's
A group of KAIST graduates from the Departments of Bio and Brain Engineering, Computer Science, Materials Science Engineering, and Industrial Design created a startup called YBrain (http://ybrain.com/). YBrain develops a wearable neuroscience technology to treat or reduce the symptoms of degenerative brain diseases such as dementia and Alzheimer’s. Their recent technological developments were covered in e27, one of the leading blogs based in Singapore. The blog covers topics like the latest technology innovation, startups, and entrepreneurship in Asia. A news article follows below:
e27, June 24, 2014
“This wearable tech may be able to combat effects of Alzheimer’s”
http://e27.co/this-wearable-tech-may-be-able-combat-effects-of-alzheimers-20140624/
2014.06.25 View 10845 -
Distinguished Professor Sang Yup Lee Attends World Economic Forum's Workshop
Sang Yup Lee, Distinguished Professor of Chemical and Biomolecular Engineering at KAIST was invited to attend the Technology Pioneer and Global Growth Company CEO Workshop hosted by the World Economic Forum (WEF) on June 19-20, 2014 in San Francisco. During the workshop, Professor Lee joined a discussion on “disruptive technologies” as a panelist.
Currently serving for the evaluation committee that selects technology pioneers for the workshop, during the discussion, Professor Lee identified important issues facing humanity, analyzed the issues through forecasting, and presented converging disruptive technologies that provide solutions to the problems. He also shared the “ten emerging technologies” announced by the Global Agenda Council on Emerging Technologies, WEF and the Korean government’s technology innovation strategies adopted to achieve its economic development policy called creative economy.
2014.06.22 View 7827 -
Professor Won Do Heo on LED Light Technology for Controlling Proteins in Living Cells
With the newly developed LED technology, Professor Won Do Heo at the College of Life Science and Bioengineering, KAIST, was able to suppress cell migration and division when cells are exposed to LED light. This suggests a breakthrough to apply in future cancer cell research.
Professor Heo talked about the impact of his research in the following excerpt from a news article:
“We are already conducting research on the spread of cancer, as well as brain science in animal models with the Light-Activated Reversible Inhibition by Assembled Trap. I believe this technology will be a breakthrough in investigating cancer treatments and the function of neurons in a complex neural network, which existing technologies have not been able to do.”
From EE Times Europe, June 19, 2014
“LED Light Technology Controls Proteins in Living Cells”
http://www.ledlighting-eetimes.com/en/led-light-technology-controls-proteins-in-living-cells.html?cmp_id=7&news_id=222909336
2014.06.22 View 7547 -
First Instance of Negative Effects from Terahertz-Range Electromagnetic Waves
Professor Philhan Kim
Electromagnetic waves (EM-wave) in the terahertz range were widely regarded as the “dream wavelength” due to its perceived neutrality. Its application was also wider than X-rays. However, KAIST scientists have discovered negative effects from terahertz EM-waves.
Professor Philhan Kim of KAIST’s Graduate School of Nanoscience and Technology and Dr. Young-wook Jeong of the Korea Atomic Energy Research Institute (KAERI) observed inflammation of animal skin tissue when exposed to terahertz EM-waves.
The results were published in the online edition of Optics Express (May 19, 20104).
Terahertz waves range from 0.1 to 10 terahertz and have a longer wavelength than visible or infrared light. Commonly used to see through objects like the X-ray, it was believed that the low energy of terahertz waves did not inflict any harm on the human body.
Despite being applied for security checks, next-generation wireless communications, and medical imaging technology, little research has been conducted in proving its safety and impact. Conventional research failed to predict the exact impact of terahertz waves on organic tissues as only artificially cultured cells were used.
The research team at KAERI developed a high power terahertz EM-wave generator that can be used on live organisms. A high power generator was necessary in applications such as biosensors and required up to 10 times greater power than currently used telecommunications EM-wave. Simultaneously, a KAIST research team developed a high speed, high resolution video-laser microscope that can distinguish cells within the organism.
The experiment exposed 30 minutes of terahertz EM-wave on genetically modified mice and found six times the normal number of inflammation cells in the skin tissue after six hours. It was the first instance where negative side effects of terahertz EM-wave were observed.
Professor Kim commented that “the research has set a standard for how we can use the terahertz EM-wave safely” and that “we will use this research to analyze and understand the effects of other EM-waves on organisms.”
2014.06.20 View 8780 -
Professor Sung Yong Kim Appointed as Committee Member to Serve PICES
The Pacific International Council for the Exploration of the Sea: North Pacific Marine Science Organization (PICES) is an intergovernmental organization, which was established in 1992 to promote and coordinate marine research in the North Pacific and adjacent areas. Currently, the United States, Canada, Japan, China, Russia, and Korea are members of the organization.
Professor Sung Yong Kim of Ocean Systems Engineering, KAIST, has been appointed to serve the Scientific and Technical Committees of PICES. He will begin his stint from July 1, 2014. During his assignment, Professor Kim will identify the need for observation of the North Pacific marine environment, develop observation methodology, and publish an annual report on the observation.
Professor Kim is an expert in marine physics and environmental fluids, with a focus on coastal circulation and dynamics, mesoscale and submesoscale eddies, integrated coastal ocean observing system, and statistical and dynamic data analysis.
2014.06.18 View 7617