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Genetic Cause of ADHD (Attention Deficit Hyperactivity Disorder) Found
The cooperative research team consisting research teams under Professor Kim Eun Joon and Professor Kang Chang Won of the department of Biological Sciences discovered that ADHD arises from the deficiency of GIT1 protein in the brain’s neural synapses.
ADHD (Attention Deficit Hyperactivity Disorder) is found in around 5% of children around the world and is a disorder where the child becomes unable to concentrate, show over the top responses, and display impulsive behavior.
The research team found that the difference between children with ADHD and those without it is one base in the GIT1 gene. The difference of a single base causes the underproduction of this protein, and those children with low levels of the protein had a higher probability to develop ADHD.
In addition, further evidence was provided when the research team conducted mice experiments. Those mice with low levels of GIT1 exhibited impulsive and exaggerated reactions like humans with ADHD, had learning disabilities, and produced abnormal brain waves. And upon injecting these mice with cure for ADHD, the symptoms of ADHD disappeared.
The impulsive behavior of ADHD children disappears as the child enters adulthood and a similar pattern was found in mice. A mice with low levels of GIT1 showed impulsive behaviors when 2 months old, but these behaviors disappeared as it got older to around 7 months old (equivalent to 20~30 years old for humans).
Professor Kim Eun Joon commented that there has to be equilibrium between mechanisms that excite the neurons and mechanisms that calm the neurons, but the lack of GIT1 leads to the decrease in the mechanisms that calm the neurons which causes the impulsive behavior of ADHD patients.
In addition, Professor Kang Chang Won commented that the results of the experiment has been receiving rave reviews and is being seen as the new method in the production of the cure for ADHD.
The result of the experiment was published in the online edition of Nature Medicine magazine.
2011.04.30 View 9953 -
The Irish Times: Gene link identified in ADHD, April 18, 2011
The Irish Times wrote an article on the recent research breakthrough made by a KAIST research team to identify a gene that triggers the syndrome of Attention Deficit Hyperactivity Disorder (ADHD) among children. Given the heightened attention to the syndrome across the world, the research result has received a great deal of attention not only from the academia but also from the media and public.
For the article, please visit http://www.irishtimes.com/newspaper/ireland/2011/0418/1224294910305.html. The research paper was appeared online April 17, 2011 in Nature Medicine, which will be printed in its May 2011 issue. For the paper, please click the link of http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.2330.html.
2011.04.18 View 9101
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KAIST Design Week 2011 Held
KAIST designated a week (from March 27th to April 2nd) as KAIST Design Week 2011 and will be hosting a series of international conferences on engineering designs.
The 21st CIRP Design Conference, the 6th International Conference on Axiomatic Design, and the 1st Design in Civil and Environmental Engineering Workshop will be held in Fusion hall in the KI Building from the 27th of March.
The CIRP Design Conference was held on the 27th and the 28th and annually provides an opportunity for researchers and industry developers to exchange information and knowledge.
The International Conference on Axiomatic Design was held on the 30th to the 31st and dealt with various presentations and discussions on the axiomatic design theory. The Axiomatic Design Theory was thought up by KAIST President Seo Nam Pyo and deals with analyzing the wants of the consumers and solves the problems associated with the product through making altercations on the product design.
Last The Design in Civil and environmental Engineering Workshop will be held on the 1st and 2nd of April and will deal with sustainable city design and development.
The Design Week will also be featuring humanoid robot HUBO, the Online Electric Vehicle that can charge its battery wirelessly, and the Mobile Harbor, and therefore show off KAIST’s achievements.
2011.04.01 View 9415
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Interdisciplinary Research on World Environmental Problems with Humanities
KAIST’s Professor Michael Pak (department of Humanities and Social Sciences) has published a paper in ‘Environmental Science and Technology, ES&T’ and was made Lead Feature.
His was the only paper published with a humanities background and his topic of discussion was ‘Environmentalism Then and Now: From Fears to Opportunities, 1970-2010’ in which he discussed the history of pro-environment activities, the patterns it showed, and its outlook.
Professor Park noted that the problems and concerns over the environment is not a recent phenomenon. It took over 50 years for the environmental problems to resurface after being the ‘hot issue’ of the time during the industrial revolution in the 19th century.
Professor Park deduced that there is a clear historical pattern.
Professor Park insisted that the two areas of Environmental Research ‘Global Warming’ and ‘Change in Weather’. Especially because these two areas are rife with uncertainty as it is, and making policies based on inaccurate information is taking a gamble.
Professor Park majored in history in UC Berkeley, received his masters’ and doctorate at Harvard University and was the professor at Massachusetts College of Art and Design before coming to KAIST at 2008.
2011.02.23 View 10522
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Explanation for the polymerized nucleic acid enzyme's abnormal activation found
KAIST’s Professor Park Hyun Kyu of the Department of Bio Chemical Engineering revealed on the 23rd of December 2010 that his team had successfully developed the technology that uses the metal ions to control the abnormal activation of nucleic acids’ enzymes and using this, created a logic gate, which is a core technology in the field of future bio electrons.
The polymerized nucleic acid enzyme works to increase the synthesis of DNA and kicks into action only when the target DNA and primers form complimentary pairs (A and T, C and G).
Professor Park broke the common conception and found that it is possible for none complimentary pairs like T-T and C-C to initiate the activation of the enzyme and thus increase the nucleic acid production, given that there are certain metal ions present.
What Professor Park realized is that the enzymes mistake the uncomplimentary T-T and C-C pairs (with stabilized structures due to the bonding with mercury and silver ions) as being complimentary base pairs. Professor Park described this phenomenon as the “illusionary polymerase activity.”
The research team developed a logic gate based on the “illusionary polymerase activity’ phenomenon.” The logic gate paves the way to the development of future bio electron needed for bio computers and high performance memories.
Professor Park commented, “The research is an advancement of the previous research carried on about metal ions and nucleic acid synthesis. Our research is the first attempt at merging the concepts of the two previously separately carried out researches and can be adapted for testing presence of metal ions and development of a new single nucleotide polymorphic gene analysis technology.”
Professor Park added that, “Our research is a great stride in the field of nano scale electron element research as the results made possible the formation of accurate logic gates through relatively cost efficient and simple system designs.”
On a side note, the research was funded by Korea Research Foundation (Chairman: Park Chan Mo) and was selected as the cover paper for the December issue of ‘Angewandte Chemie International Edition’.
2011.01.18 View 9937 -
Reasons for Hope: Jane Goodall Lectured at KAIST
Dr. Jane Goodall, globally acknowledged chimpanzee researcher and environmental activist, was invited to KAIST and gave a lecture on the importance of preservation and restoration of the ecosystem on the earth. The lecture took place on the 28 of September at the university’s auditorium from 5PM to 7PM.
The lecture, titled “Reasons for Hope: Celebrating 50 Years of Chimpanzee Research,” was organized to celebrate her longtime career as a primatologist and anthropologist.
The visiting of Dr. Jane Goodall, who had dedicated a long period of time in spreading the significance of the diversity of life, gave a meaningful opportunity to increase the Korean public’s awareness of life’s diversity.
This lecture was jointly sponsored by Ehwa Woman’s University and KAIST, and the lecture was translated by Professor Choi Jae-Chun of Ehwa University.
2010.09.29 View 8904 -
KAIST was invited to the World Economic Forum's fourth "Summer Davos."
KAIST attended the World Economic Forum’s “Summer Davos Forum” held from September 13 to 15 in Tianjin, China. The Summer Davos Forum hosted various sessions and meetings with international dignitaries from governments, business and public organizations, and academia on the main theme of “Driving Growth through Sustainability.”
On September 14, four subjects including “Electric Vehicles,” “Humanoid Robotics,” “Next Generation of Biomaterials,” and “New Developments in Neuroengineering” were presented by KAIST, followed by discussions with forum participants.
Professor Jae-Seung Jeong of the Bio and Brain Engineering Department, Sang-Yup Lee of the Chemical and Biomolecular Engineering Department, Joon-Ho Oh of the Mechanical Engineering Department, and President Nam-Pyo Suh participated in the forum as presenters of the topic. Of these speakers, Professors Jae-Seung Jeong and Sang-Yup Lee were nominated by the World Economic Forum (WEF) as members of the “Young Global Leader” and “Global Agenda Council on Emerging Technologies,” respectively.
President Suh was also invited to the CEO Insight Group and delivered an opening speech on OLEV (Online Electric Vehicle) and the Mobile Harbor. President Suh plans to sign an MOU for research cooperation with Jong-Hoo Kim of Bell Lab and Shirley Jackson of the Rensselaer Polytechnic Institute in the near future, respectively.
Since 2007, the WEF, in charge of the world’s largest international conference called “Davos Forum” has hosted a “Summer Davos Forum,” also called as the “Annual Meeting of New Champions.” The Summer Davos Forum consists of nations, rising global companies, next generation of global leaders, and cities or nations that lead technological innovations. Unlike the annual Davos Forum held in January, the “Annual Meeting of New Champions” is held in September of each year in Tianjin and Dalian, China.
Since 2009, the WEF has added a special session called IdeasLab in the Davos and Summer Davos Forums. Through IdeasLab, prominent universities from all over the world, research organizations, venture businesses, NGOs, and NPOs are invited to exchange and discuss innovative and creative ideas that can contribute to the development of mankind. Until now, universities including INSEAD, EPFL-ETH, MIT, Oxford, Yale, Harvard, Rensselaer Polytechnic Institute, Tsinghua University, and Keio University have been invited to the IdeasLab. KAIST is the first Korean university to attend this session.
2010.09.17 View 17449 -
A graduate-level education for working professionals in science programs and exhibitions will be available from mid-August this year.
The Graduate School of Culture Technology (GSCT), KAIST, has created a new course for professionals who purse their career in science programs and exhibitions, which will start on August 19 and continue through the end of November 2010. The course will be held at Digital Media City in Seoul.
The course, also co-sponsored by National Science Museum, will offer students tuition-free opportunities to brush up their knowledge on the administration, policy, culture, technology, planning, contents development, and technology & design development, of science programs and exhibitions. Such subjects as science contents, interaction exhibitions, and utilization of new media will be studied and discussed during the course. Students will also have a class that is interactive, engaging, and visual, as well as provides hands-on learning activities.
A total of 30 candidates will be chosen for the course. Eligible applicants are graduates with a B.S. degree in the relevant filed, science program designers and exhibitors, curators for science and engineering museums, and policy planners for public and private science development programs.
2010.08.12 View 10964
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Prof. Seong Publishes English Book on Reliability in Digital Control Systems
Prof. Poong-Hyun Seong of Department of Nuclear and Quantum Engineering has recently published an English-language book on reliability and risk issues in large scale safety-critical digital control systems used in complex facilities such as nuclear power plants.
The book entitled “Reliability and Risk Issues in Large Scale Safety-critical Digital Control Systems” is a result of Prof. Seong’s collaboration with some KAIST graduates who used to be under his guidance. The 303-page publication has been published by Springer, one of the world’s leading publishers of academic journals, as part of the Springer Series in Reliability Engineering.
The book consists of four parts; part I deals with issues related to hardware, part II software, part III human factors and finally the last part integrated systems. It can be purchased through some on-line book stores such as Amazon.com.
Prof. Seong served as an editor-in-chief for Nuclear Engineering and Technology (NET), an international journal of Korean Nuclear Society (KNS), from 2003 to 2008. He also worked as a chair of the Human Factors Division (HFD) of American Nuclear Society (ANS) from 2006 to 2007. Prof. Seong is now a commissioner of Korea Nuclear Safety Commission which is the nation’s highest committee on Nuclear Safety.
2008.12.26 View 14951
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Home-Grown Transparent Thin Film Transistor Developed
KAIST, Aug. 6, 2008 -- A KAIST research team led by Profs. Jae-Woo Park and Seung-Hyup Yoo of the Electrical Engineering Division has developed a home-grown technology to create transparent thin film transistor using titanium dioxide., university authorities said.The KAIST team made the technological advance in collaboration with the LCD Division of Samsung Electronics and the Techno Semichem Co., a local LCD equipment maker. Transparent thin film transistor continues to enjoy a wealth of popularity and intensive research interest since it is used in producing operating circuits including transparent display, active-matrix OLED (AMOLED) display and flexible display.
The new technology is significant in that it is based on a titanium dioxide, the first such attempt in the world, while the technologies patented by the United States and Japan are based on ZnO.
Researchers will continue to work on securing technological reliability and developing a technology to mass-produce in a large-scale chemical vapor deposition equipment for the next couple of years.
"The development of technology to produce transparent thin film transistor will help Korean LCD makers reduce its dependence on foreign technologies, as well as maintain Korea"s status as a leader of the world"s display industry," said Prof. Park.
KAIST has applied for local patent registration of the technology and the process is expected to complete by this October or November. International patents have been also applied for in the U.S., Japan and Europe.
The new technology was introduced in the latest edition of the Electron Device Letters, a journal published by the Institute of Electrical and Electronics Engineers or IEEE, a New York-based international non-profit, professional organization for the advancement of technology related to electricity. It will be presented at the International Display Workshop 2008 on Dec. 5 in Niigata, Japan.
2008.08.07 View 14206 -
KAIST To Open Cultural Activity Classes
KAIST To Open Cultural Activity Classes
KAIST will open classes of Cultural Activity (CA) this fall semester, and many of them will be instructed by students.
CA classes are regular classes opened to create a better atmosphere on campus and broaden students’ sociality and provide opportunities of diverse experiences to enhance students’ qualities as elite scientists. All classes will be provided at night or weekend to allow students to take part in cultural activities of their interests.
Total 21 classes, such as animation, photo-taking, electronic guitar, classic guitar, Ocarina, Inline skate, Haedong kendo, weight training, yoga, Tae-keuk-kwon, aerobic, recreation, hacking, drum playing, etc., will be provided, and 15 of them, such as animation, photo-taking, electronic guitar, etc., will be lectured by students. The students-lectured classes have been selected after thorough examination of lecture plans.
Leadership Mileage Points (LMP) will be offered to students both of lecturing and attending CA classes and, in the case of freshmen, a credit will be admitted for the obligatory subject of leadership demanding two credits. A larger number of students than the enrollment capacity have applied for the classes within a day. CA classes are expected to change campus life in KAIST.
Meanwhile, students will be given LMPs for each of their activities, such as humanity/ leadership lectures, on-campus voluntary services, off-campus voluntary services, mind and body training, exchange student activity, field experiences, etc., and will be issued a leadership certificate graded as ‘silver’, ‘gold’, ‘platinum’ and ‘diamond’ according to the accumulative LMPs in graduation. A personal certificate describing the details of on-campus activities by students will also be issued to help students’ employment activities.
KAIST has recently introduced a new two-dimensional admission policy that evaluates applicants’ humanities as well as academic achievements, based on President Suh’s judgment that students with expertise but no humanity will not be able to create the bright future of Korea. The LMP has the same purport as the new policy in that enrolled students are also to be evaluated in two aspects - humanity and academic achievements, and will bring a new paradigm to Korean education.
2007.06.08 View 11647
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KAIST to build large-scale civil engineering experiment center
- Geo-Centrifuge experiment center of an area of about 1,712 square meters and an estimated construction cost of total 8.4 billion won
- Simulation laboratory in the field of geotechnical engineering with state-of-the-art experiment equipment- Ground-breaking ceremony held on April 3 at 4 pm
KAIST will construct ‘distributed shared-type Geo-Centrifuge experiment center’, a large-scale civil engineering laboratory that will study natural disasters such as earthquake, embankment collapse, etc. with ground structure miniatures.
A two-story building with a basement occupying an area of about 1,712 square meters will become a landmark laboratory in the field of geotechnical engineering that can be used for the education, research, and social infrastructure design by universities, institutes, and corporations via high-speed information and communication network. The estimated construction cost is 8.4 billion won.
The center will be composed of experiment building including geo-centrifuge laboratory, model-making room, workshop, geotechnical engineering laboratory, and specimen storehouse; and research building including control room, video conference room, electronic library, and research rooms. A variety of convenience facilities for researchers and video conference and remote monitoring system, with which researcher at remote distances can directly participate in experiments, will be provided in the research building, and world’s top-class experiment equipment such as geo-centrifuge with a turning radius of 5 meters, a maximum acceleration of 130 G (130 times faster than the acceleration of gravity), a preload of 2,400 kg and bidirectional shaking-table that can reproduce earthquakes-like wave during experiments, and robots that can reproduce construction procedures by a remote control will be installed.
Geo-Centrifuge experiment refers to an experiment that reproduces natural disaster-like motions by making miniatures of large-scale ground structures such as dams, slopes, etc. and using centrifugal forces generated from high-speed rotation. This experiment can easily and rapidly reproduce actual motions of ground structures at a low cost, thereby being widely used for various geotechnical engineering researches such as evaluation of seismic safety, movement of soft ground, slope stability analysis, etc. The causes of the embankment collapse in New Orleans by Hurricane Katrina in 2005 were also revealed by simulation tests by this experiment.
“The center will make possible a variety of experiments and researches that have never been available in Korea due to the lack of experiment infrastructure, therefore activate researches over the design and construction of large-scale social infrastructures. Making possible civil engineering researches demanding the use of large-scale equipment like Centrifuge, severely dependent on overseas technologies so far, will enhance the global competitiveness of Korean construction industry,” said Dong-soo Kim, President of the center.
The center will be constructed as part of the Ministry of Construction & Transportation (MOCT)’s project for the establishment of distributed shared-style construction research infrastructure, which is designed to establish construction research infrastructures in a national level. The ground breaking ceremony was held at KAIST on April 3 at 4 pm.
2007.04.12 View 14097