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College of Cultural Sciences Announces Results for 6th Best Paper Award
The College of Cultural Sciences cohosts with the EFL Program the Best Paper Award each semester. The Best Paper Awards went to Jo Hyeong Chan and Oh Shin Ah undergraduate students. The Best Paper Award was established in 2009 in order to encourage and improve the English writing skills of undergraduate students.
The College of Humanities and Social Sciences opened up 69 English courses in Spring of 2012 and 14 papers were recommended by the respective professors as ‘best papers’. Out of these papers 2 were selected for First Prize and 4 were selected as Honorable Mentions. The two recipients’ papers were recommended by Professor Park Woo Seok (Topics in Philosophy).
2012.10.16 View 7005 -
2012 Intellectual Property Rights Award Ceremony Held
The 2012 Intellectual Property Rights Award Ceremony was held at Seoul KAIST Campus.
Recipients of the award included former congressmen Kim Young Sun and Lee Jeong Hyuk, and Kim Boo Kyung researcher at Electronics and Telecommunications Research Institute also representing Vooz Ltd. that created the character POOCA.
The Intellectual Property Rights Award is given to an individual or a group that succeeded in utilizing, protecting, creating, and establishment of its foundation including patent, copyright, and brand. Intellectual Property Rights is viewed as of importance for future national competitiveness.
The Award is organized by the Korea Patent Attorneys Association, the Korea Association of Intellectual Property Services, and KAIST and are respectively core institutions in the training of Intellectual Property Rights Experts and the creation, utilization, and the protection of intellectual property.
In addition the Award is also co-organized by the KAIST Graduate School of Intellectual Property Rights (established in cooperation with KAIST and the Korean Intellectual Property Office) and the total 20 million Won of prize money is funded by Korea Institute of Intellectual Strategy and Kim Ok Lan Foundation.
The Award Ceremony was held with a special lecture by the recipients.
It was stressed that the evaluation process was carried out with that the decision is a silent message to the society and is also a type of market signal.
Director Ko Gi Seok (Presidential Council on Intellectual Property) revealed that the candidates’ impact on the strength of national intellectual property rights was thoroughly scrutinized.
In the criteria of Creation of Intellectual Property, ETRI received the award in recognition of the institution’s successful patenting and commercializing of products of Korean R&D.
ETRI created a total of 251 International Patents in cooperation with ITU, ISO, IEE, etc. and also participated in a total of 9 International Standard Patent Pool, showing its active Intellectual Property management.
Such efforts ranked ETRI 1st in the United States Patent Evaluation performed by the US Patent Board in 2011 out of 237 institutions.
In addition Recipient of the Intellectual Property Utilization criteria, VOOZ ltd.’s Kim Boo Kyung promised the free use of their character POOCA in ETRI’s automated Korean-English translator. Researcher Kim Boo Kyung was rewarded with the award in recognition of his contribution to the domestic economy and realization of the commercialization of a copy right through licensing.
Former congressman Kim Young Son received an Award in the Foundation criteria in recognition of his efforts in the establishment of the Presidential Council on Intellectual Property and the Basic Blueprints for the Intellectual Property Law.
Former congressman Lee Jeong Hyuk received the same award in recognition of standardization and streamlining Intellectual Property Rights Policies. His realization and pursuit of the establishment of a balanced growth based on law for the competitiveness of businesses was the driving force behind his accomplishments.
2012.10.16 View 10223
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Anonymous philanthropist donates 5.5 billion won to KAIST
An unnamed philanthropist donated a large sum of money to KAIST to be used as funds for the school"s development.
On September 6th, the donor met with President Suh to donate a sum of 5.5 billion won to the school for the development of science and technology.
A KAIST representative announced that the donor did not want to be named and that he was greatly impressed by President Suh"s and KAIST"s efforts towards reformation. The philanthropist wanted the donation to be used for research funds and financial aid.
President Suh said that "KAIST was deeply thankful and that it would work harder to show fulfill the donor"s wishes" and that the money would indeed be used for research and the students.
This was the 6th largest donation since the start of President Suh"s post in July 2006. Since 2006, the accumulated KAIST development fund has increased 30 times, from 5.9 billion won at the end of 2006 to 180 billion won in September 2012.
2012.09.24 View 6735
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Liver Damage Mechanism of Hepatitis C Proven
KAIST researchers found mechanics behind a Hepatitis C virus, thereby taking a step closer to the development of a cure for Hepatitis C.
Professor Choi Chul Hui (Department of Biological and Brain Engineering) and Professor Shin Eui Chul (Graduate School of Medical Sciences) proved, for the first time in the world, the mechanism behind liver damage of a patient with Hepatitis C.
It is anticipated that this discovery will allow for the development of a Hepatitis C cure that has no side effects and little Liver damage.
Hepatitis C is an immune response of the body to the Hepatitis C virus and causes liver irritation.
Around 170million people are infected with Hepatitis C worldwide including 1% of the Korean population. Once infected, most cases turn into chronic cases and may lead to liver cancer.
However it was impossible to infect Hepatitis C within a test tube cell environment until 2005 and up till then Chimpanzees were used to study the virus which proved to be a huge barrier to research.
The research team used cells infected with Hepatitis C virus and found out that the virus works by increasing the destruction of cells by the TNF-a protein responsible for the cell’s immune response.
In addition the protein structure of the virus that causes this reaction was successfully found.
Conventionally the Hepatitis C medication focused on the suppressing the growth of the virus and therefore had many side effects.
The experimental results allow new medication aimed at suppressing the actual mechanism of liver damage to be discovered.
The result was selected as the cover dissertation of the September Edition of the Hepatolog magazine.
2012.09.11 View 11483
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Jellyfish removal robot developed
Professor Myung Hyun’s research team from the Department of Civil and Environmental Engineering at KAIST has developed a jellyfish removal robot named ‘JEROS’ (JEROS: Jellyfish Elimination RObotic Swarm).
With jellyfish attacks around the south-west coast of Korea becoming a serious problem, causing deaths and operational losses (around 3 billion won a year), Professor Myung’s team started the development of this unmanned automatic jellyfish removal system 3 years ago.
JEROS floats on the surface of the water using two long cylindrical bodies. Motors are attached to the bodies such that the robot can move back and forth as well as rotate on water. A camera and GPS system allows the JEROS to detect jellyfish swarm as well as plan and calculate its work path relative to its position.
The jellyfish are removed by a submerged net that sucks them up using the velocity created by the unmanned sailing. Once caught, the jellyfish are pulverized using a special propeller.
JEROS is estimated to be 3 times more economical than manual removal. Upon experimentation, it showed a removal rate of 400kg per hour at 6 knots. To reach similar effectiveness as manual net removal, which removes up to 1 ton per hour, the research team designed the robot such that 3 or more individual robots could be grouped together and controlled as one.
The research team has finished conducting removal tests in Gunsan and Masan and plan to commercialize the robot next April after improving the removal technology. JEROS technology can also be used for a wide range of purposes such as patrolling and guarding, preventing oil spills or removing floating waste. This research was funded by the Ministry of Education, Science and Technology since 2010.
2012.08.29 View 11185
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First Annual CanSat Idea Exhibition held
The Ministry of Education, Science, and Technology held the ‘CanSat’ Exhibition in order to increase interest and understanding of satellites in primary, secondary, and high school level students.
The exhibition, hosted by KAIST Satellite Research Center and funded by Korea Aerospace Institute, was held in SaeJeong City.
90 primary, secondary school teams, 57 high school teams, and 14 university teams submitted their applications for participation. Of these teams 20 primary, secondary school teams, 5 high school teams, and 5 university teams were selected after thorough document valuation and presentation assessment.
The 20 primary, secondary school teams participated in the science camp to gain firsthand experience in the construction and launch of a simple satellite system.
The high school and university teams were evaluated by the level of completion of the task given and the level of creativity involved.
The CanSat Exhibition has been held in aerospace powerhouses and this was the first time such an exhibition was held in Korea.
2012.08.21 View 8262
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Graduate School of Culture and Technology Begins Mobile Science Classroom
KAIST Graduate School of Culture and Technology plans visits to elementary schools without the facilities to facilitate hands on science education.
The Graduate School of Culture and Technology planned the ‘STEAM Creative Camp’ involving three elementary schools during the summer holidays.
The ‘STEAM Creative Camp’ involves increasing interest and artistic sensitivity through experience based science education.
The program is composed of two separate programs in consideration to the level of participating students.
The beginner level program includes: code making, writing secret letters, sticker decorating program and the moderate level program includes: making wipers using complex pulley system, catapult design using elasticity, and puppet show using joints to animate.
The programs will be taught by masters and doctorate program candidates from the KAIST Youth Culture and Technology Experience Center.
*STEAM: And integrated education system including Science, Technology, Engineering, Arts, and Mathematics.
2012.07.26 View 8285
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Commercialization of Carbon Capture and Storage Technology Speeds up
KAIST research team successfully developed the ideal method for carbon dioxide transportation, which is crucial in the capturing and underground storage of carbon dioxide technology.
Professor Jang Dae Joon of the department of Ocean Systems Engineering developed a carbon dioxide transportation that minimizes evaporative gases.
The new technology is the final piece of the three part carbon capture storage which involves capture, transportation, and storage of carbon dioxide. The completion of the three part technology will allow for commercialization in the near future.
Carbon Capture and Storage technology is regarded as the technology that will reduce carbon dioxide levels. It captures the carbon dioxide emitted from power plants and factories and storing them permanently in empty oil fields underground.
If the post Kyoto Protocol was to be implemented from 2013, Korea will not be able to shirk from the need to reduce carbon emissions. Therefore the Korean government set out to reduce 32 million tons of carbon dioxide (10% of predicted carbon reduction) until 2030. In response to the government’s efforts to reduce carbon dioxide emissions, Korean research teams like KAIST have responded.
Professor Jang’s team succeeded in developing the core technology for underground storage in the 2009 ‘Carbon dioxide Transport and Injection Terminal Project’. And as the final piece of the puzzle the team developed an optimization solution that addressed the evaporating gases emitted from carbon dioxide during transportation.
Professor Jang’s team focused on the required low temperature and high pressure conditions in liquid carbon dioxide transport.
The problem lies in the temperature gradient which can cause the transport canister to explode.
The solution developed by the team is to evaporate carbon dioxide in a pressurized contained which is then re-liquidated.
External variables like price of oil, carbon taxation, etc. have been considered and the process was optimized accordingly.
The result of Professor Jang’s team’s solution to Carbon Capture and Storage was stored in the online edition of International Journal of Greenhouse Gas Control.
2012.07.26 View 8909
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KAIST researchers verify and control the mechanical properties of graphene
KAIST researchers have successfully verified and controlled the mechanical properties of graphene, a next-generation material. Professor Park Jung Yong from the EEWS Graduate School and Professor Kim Yong Hyun from the Graduate School of Nanoscience and Technology have succeeded in fluorinating a single atomic-layered graphene sample and controlling its frictional and adhesive properties. This is the first time the frictional properties of graphene have been examined at the atomic level, and the technology is expected to be applied to nano-sized robots and microscopic joints.
Graphene is often dubbed “the dream material” because of its ability to conduct high amounts of electricity even when bent, making it the next-generation substitute for silicon semiconductors, paving the way for flexible display and wearable computer technologies. Graphene also has high potential applications in mechanical engineering because of its great material strength, but its mechanical properties remained elusive until now.
Professor Park’s research team successfully produced individual graphene samples with fluorine-deficiency at the atomic level by placing the samples in Fluoro-xenon (XeF2) gas and applying heat. The surface of the graphene was scanned using a micro probe and a high vacuum atomic microscope to measure its dynamic properties.
The research team found that the fluorinated graphene sample had 6 times more friction and 0.7 times more adhesiveness than the original graphene. Electrical measurements confirmed the fluorination process, and the analysis of the findings helped setup the theory of frictional changes in graphene.
Professor Park stated that “graphene can be used for the lubrication of joints in nano-sized devices” and that this research has numerous applications such as the coating of graphene-based microdynamic devices.
This research was published in the online June edition of Nano Letters and was supported by the Ministry of Science, Technology, and Education and the National Research Foundation as part of the World Class University (WCU) program.
2012.07.24 View 14192 -
Systems biology demystifies the resistance mechanism of targeted cancer medication
Korean researchers have found the fundamental resistance mechanism of the MEK inhibitor, a recently highlighted chemotherapy method, laying the foundation for future research on overcoming cancer drug resistance and improving cancer survival rates. This research is meaningful because it was conducted through systems biology, a fusion of IT and biotechnology.
The research was conducted by Professor Gwang hyun Cho’s team from the Department of Biology at KAIST and was supported by the Ministry of Education, Science and Technology and the National Research Foundation of Korea.
The research was published as the cover paper for the June edition of the Journal of Molecular Cell Biology (Title: The cross regulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor).
Targeted anticancer medication targets certain molecules in the signaling pathway of the tumor cell and not only has fewer side effects than pre-existing anticancer medication, but also has high clinical efficacy. The technology also allows the creation of personalized medication and has been widely praised by scientists worldwide.
However, resistances to the targeted medication have often been found before or during the clinical stage, eventually causing the medications to fail to reach the drug development stage. Moreover, even if the drug is effective, the survival rate is low and the redevelopment rate is high.
An active pathway in most tumor cells is the ERK (Extracellular signal-regulated kinases) signaling pathway. This pathway is especially important in the development of skin cancer or thyroid cancer, which are developed by the mutation of the BRAF gene inside the path. In these cases, the MEK (Extracellular signal-regulated kinases) inhibitor is an effective treatment because it targets the pathway itself. However, the built-up resistance to the inhibitor commonly leads to the redevelopment of cancer.
Professor Cho’s research team used large scale computer simulations to analyze the fundamental resistance mechanism of the MEK inhibitor and used molecular cell biological experiments as well as bio-imaging* techniques to verify the results.
* Bio-imaging: Checking biological phenomena at the cellular and molecular levels using imagery
The research team used different mutational variables, which revealed that the use of the MEK inhibitor reduced the transmission of the ERK signal but led to the activation of another signaling pathway (the PI3K signaling pathway), reducing the effectiveness of the medication. Professor Cho’s team also found that this response originated from the complex interaction between the signaling matter as well as the feedback network structure, suggesting that the mix of the MEK inhibitor with other drugs could improve the effects of the targeted anticancer medication.
Professor Cho stated that this research was the first of its kind to examine the drug resistivity against the MEK inhibitor at the systematic dimension and showed how the effects of drugs on the signaling pathways of cells could be predicted using computer simulation. It also showed how basic research on signaling networks can be applied to clinical drug use, successfully suggesting a new research platform on overcoming resistance to targeting medication using its fundamental mechanism.
2012.07.06 View 10496
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The hereditary factor of autism revealed
Korean researchers have successfully investigated the causes and hereditary factors for autistic behavior and proposed a new treatment method with fewer side effects.
This research was jointly supported by the Ministry of Education, Science and Technology and the National Research Foundation as part of the Leading Researcher and Science Research Center Program
The research findings were publishing in the June edition of Nature magazine and will also be introduced in the July edition of Nature Reviews Drug Discovery, under the title ‘Autistic-like social behavior in Shank2-mutant mice improved by restoring NMDA receptor function’.
The research team found that lack of Shank2 genes in mice, which are responsible for the production of synapse proteins, caused autistic-like behavior. The results strongly suggested that the Shank2 gene was linked to autistic behavior and that Shank2 deficiency induced autistic behaviors.
Autism is a neural development disorder characterized by impaired social interaction, repetitive behavior, mental retardation, anxiety and hyperactivity. Around 100 million people worldwide display symptoms of autistic behavior. Recent studies conducted by the University of Washington revealed that 1 out of 3 young adults who display autistic behavior do not fit into the workplace or get accepted to college, a much higher rate than any other disorder. However, an effective cure has not yet been developed and current treatments are limited to reducing repetitive behavior.
The research team confirmed autistic-like social behavior in mice without the Shank2 genes and that the mice had decreased levels of neurotransmission in the NMDA receptor. The mice also showed damaged synaptic plasticity* in the hippocampus**.
* Plasticity: ability of the connectionbetween two neurons to change in strength in response to transmission of information
**Hippocampus: part of the brain responsible for short-term and long-term memory as well as spatial navigation.
The research team also found out that, to restore the function of the NMDA receptor, the passive stimulation of certain receptors, such as the mGLuR5, yielded better treatment results than the direct stimulation of the NMDA. This greatly reduces the side effects associated with the direct stimulation of receptors, resulting in a more effective treatment method.
This research successfully investigated the function of the Shank2 gene in the nerve tissue and showed how the reduced function of the NMDA receptor, due to the lack of the gene, resulted in autistic behavior. It also provided new possibilities for the treatment of autistic behavior and impaired social interaction
2012.06.24 View 10827
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Successful Development of Excavation System of Biomarkers containing Protein Decomposition Control Enzyme Information
A Korean team of researchers successfully developed a biomarker excavation system named E3Net that excavates biomarkers containing information of the enzymes that control the decomposition of proteins. The development of the system paved the possibility of development of new high quality biomarkers.
*Biomarker: Molecular information of unique patterns derived from genes and proteins that allow the monitoring of physical changes from genetic or environmental causes.
Professor Lee Kwan Soo’s team (Department of Biological Sciences) composed of Doctorate candidate Han Young Woong, Lee Ho Dong Ph.D. and Professor Park Jong Chul published a dissertation in the April edition of Molecular and Cellular Proteomics. (Dissertation Title: A system for exploring E3-mediated regulatory networks of cellular functions).
Professor Lee’s team compiled all available information of the enzyme that controls protein decomposition (E3 enzyme) and successfully compiled the inter-substrate network by extracting information from 20,000 biology related data base dissertations. The result was the development of the E3Net system that analyzes the related cell function and disease.
Cells have a system that produces, destroys, and recycles proteins in response to the ever changing environmental conditions. Error in these processes leads to disease.
Therefore finding the relationship between E3 enzymes that control the decomposition of proteins and the substrates will allow disease curing and prevention to become much easier. E3 enzyme is responsible for 80% of the protein decomposition and is therefore predicted to be related to various diseases.
However the information on E3 enzyme and inter-substrate behavior are spread out among numerous dissertations and data bases which prevented methodological analysis of the role of the related cells and characteristics of the disease itself.
Professor Lee’s team was successful in creating the E3Net that compiled 2,201 pieces of E3 substrate information, 4,896 pieces of substrate information, and 1,671 pieces of inter-substrate relationship information. This compilation allows for the systematic analysis of cells and diseases.
The newly created network is 10 times larger than the existing network and is the first case where it is possible to accurately find the cell function and related diseases.
It is anticipated that the use of the E3Net will allow the excavation of new biomarkers for the development of personalized drug systems.
The research team applied the E3Net to find tens of new candidate biomarkers related to the major modern diseases like diabetes and cancer.
2012.05.30 View 11767