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KAIST receives $20 million donation for futures studies
A retired businessman, Moon-Soul Chung, the former chief executive officer of Mirae, Inc., a semiconductor equipment company in Korea, today donated USD 20 million to the Graduate School of Future Strategy at KAIST. It was Chung's second contribution to KAIST—his first donation of USD 28 million in 2001 supported the construction of the Bio and Brain Engineering building, a major research center on campus where biotechnology and information technology converge. Established in 2013, the KAIST Graduate School of Future Strategy consists of three interdisciplinary graduate programs on future strategy, intellectual property, and science journalism. The Research Center for Future Strategy is an affiliate of the graduate school. KAIST is the first Korean university that offers an academic program granting a degree in futures studies. The rapid advancement in science and technology today affects, profoundly and extensively, all corners of global society from education, politics, economy, and environment to resources, sustainability, and inequality. As we live in a highly interconnected, digitalized, and unpredictable world, analyzing the events, trends, patterns, and changes of the past and present, developing foresight, and mapping preferred futures have become more relevant than ever. KAIST utilizes its strong tech-knowledge base in science and engineering to offer students a high quality education and training in futures thinking, skills, and methodologies to develop foresight and to plan future strategies for international relations, business and industry, national defense, science and technology, and new media. KAIST also anticipates helping government, business, public service, and non-profit organizations identify important issues and develop long-range implementation strategies to prepare for probable and preferred futures. Moon-Soul Chung (left), the former CEO of Mirae Inc., and President Steve Kang (right), holding together the donation agreement in Seoul, January 10th, 2014
2014.01.13
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Mechanism in regulation of cancer-related key enzyme, ATM, for DNA damage and repair revealed
Professor Kwang-Wook Choi A research team led by Professor Kwang-Wook Choi and Dr. Seong-Tae Hong from the Department of Biological Sciences at KAIST has successfully investigated the operational mechanism of the protein Ataxia Telangiectasia Mutated (ATM), an essential protein to the function of a crucial key enzyme that repairs the damaged DNA which stores biometric information. The results were published on December 19th Nature Communications online edition. All organisms, including humans, constantly strive to protect the information within their DNA from damages posed by a number of factors, such as carbonized materials in our daily food intake, radioactive materials such as radon emitting from the cement of buildings or ultraviolet of the sunlight, which could be a trigger for cancer. In order to keep the DNA information safe, the organisms are always carrying out complex and sophisticated DNA repair work, which involves the crucial DNA damage repair protein ATM. Consequently, a faulty ATM leads to higher risks of cancer. Until now, academia predicted that the Translationally Controlled Tumor Protein (TCTP) will play an important role in regulating the function of ATM. However, since most of main research regarding TCTP has only been conducted in cultured cells, it was unable to identify exactly what mechanisms TCTP employs to control ATM. The KAIST research team identified that TCTP can combine with ATM or increase the enzymatic activity of ATM. In addition, Drosophilia, one of the most widely used model organisms for molecular genetics, has been used to identify that TCTP and ATM play a very important role in repairing the DNA damaged by radiation. This information has allowed the researchers to establish TCTP’s essential function in maintaining the DNA information in cell cultures and even in higher organisms, and to provide specific and important clues to the regulation of ATM by TCTP. Professor Kwang-Wook Choi said, “Our research is a good example that basic research using Drosophilia can make important contributions to understanding the process of diseases, such as cancer, and to developing adequate treatment.” The research has been funded by the Ministry of Science, ICT and Future Planning, Republic of Korea, and the National Research Foundation of Korea. Figure 1. When the amount of TCTP protein is reduced, cells of the Drosophila's eye are abnormally deformed by radiation. Scale bars = 200mm Figure 2. When the amount of TCTP protein is reduced, the chromosomes of Drosophilia are easily broken by radiation. Scale bars = 10 mm. Figure 3. When gene expressions of TCTP and ATM are reduced, large defects occur in the normal development of the eye. (Left: normal Drosophilia's eye, right: development-deficient eye) Figure 4. ATM marks the position of the broken DNA, with TCTP helping to facilitate this reaction. DNA (blue line) within the cell nucleus is coiled around the histone protein (green cylinder). When DNA is broken, ATM protein attaches a phosphate group (P). Multiple DNA repair protein recognizes the phosphate as a signal that requires repair and gathers at the site.
2014.01.07
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Professor Yong-Hee Lee of Physics Received the Humboldt Research Award
In recognition of his past accomplishments in research and teaching, Professor Yong-Hee Lee of Physics at KAIST received the Humboldt Research Award in November 2013. The Humboldt Research Award is annually given by the Alexander von Humboldt Foundation to internationally renowned scientists and scholars in the fields of biology, chemistry, computer science, economics, linguistics, management, mathematics, medicine, philosophy, and physics. The winners of the award are offered with 60,000 Euros of research grant as well as an opportunity to undertake prolonged periods of research in collaboration with researchers in Germany.Professor Lee, who may be the first Korean physicist receiving the award, plans to conduct joint research with colleagues at the Technical University of Berlin and University of Würzburg.
2014.01.05
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Professor Kwy-Ro Lee Appointed Distinguished Member of IEEE
Professor Kwy-Ro Lee from the Department of Electrical Engineering at KAIST was selected as a distinguished member of the Institute of Electrical and Electronics Engineers (IEEE) where his contribution to research development of the technological management of semiconductors was recognized. Professor Lee earned his BS from Seoul National University and MS & Ph.D. from the University of Minnesota. He has been working as a professor in the Department of Electrical Engineering since 1986. He has also served as the president of the LG Electronics Research Center in 2005 and the president of the Nanoscience and Technology Center at KAIST in 2010. IEEE is the largest professional association for the advancement of technology in electrical, electronics, computing and communication with 400,000 members in 160 countries. Only 0.1 percent of members with over ten years of service can be selected as distinguished members based on their research devotion for society.
2014.01.02
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KAIST Student Awarded Prize from Energy Saving Contest
Jun-Min Kwon, an undergraduate student in the Department of Chemistry at KAIST, was awarded a prize from the Ministry of Trade, Industry and Energy, Republic of Korea, at the 35th Energy Saving Contest which was held on November 20. The student club he has been leading was also selected as one of the best groups by the Save Energy Save Earth (SESE), a volunteer organization supported by the Korea Energy Management Corporation and the Ministry of Knowledge Economy, Republic of Korea. Kwon began promoting energy conservation through a blog and participated in related meetings and workshops as a high school student to improve the understanding on the importance of energy saving and recycling.He also received awards from the Second National Assembly Forum on Climate Change, the Korean National Science Fair, as well as the Samsung Human Tech Paper Award.
2013.12.24
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Professor Suk-Joo Na Invited to Finland as Distinguished Professor
Professor Suk-Joo Na, from the Department of Mechanical Engineering at KAIST, has been invited as a distinguished professor for an international research project in Finland. As a leading scientist in the field of arc welding and numerical analysis of the laser welding process, Na will assemble a research group for the interpretation of the welding processes for three years at the VVT Technical Research Centre of Finland beginning in January of 2014. The project was established to improve the research level and national competitiveness of Finland by inviting leading international scientists to the National Technology Agency of Finland and Academy of Finland since 2006 and over one hundred projects have been carried out thus far. A total of 17 billion won will be invested for the eleven new projects selected this year. Professor Na said, “The fusion welding field contains important technology for improving the competitiveness of mechanical products of Finland. Improvements in productivity, the life cycles of products, and energy saving through interpretation technology for the numerical analysis of the welding process will make a huge impact on the national economy of Finland.”
2013.12.24
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Nanoparticle based Super Lens selected as 2013 Science and Technology News
Professor Yong-keun Park "Nanoparticle-based Super Lens", an article by KAIST Physics Department’s Professor Yong-keun Park and Professor Yong-hoon Cho’s joint research team, has been selected as one of the ten representative 2013 Science and Technology News, by the Korea Federation of Science and Technology Societies. This new concept super lens uses the scattering of light, which can yield over three times more superior resolution of previous optical lenses. Unlike the conventional optical lens that utilizes refraction of the light, the super lens can give the image of viruses and structure within the cell at 100㎚. This lens is also applicable to state-of-the-art optical and semiconductor processes. In addition, this year's research achievements also include the successful launch of Naro, a new technology to remove the brain cell membrane which gives a more transparent view of the brain, a new drug to inhibit cancer metastasis, as well as the development of ultra-wide-angle insect eye camera technology. Articles for 2013 Science and Technology News are chosen in three trial reviews by committee and online voting by 5,437 people over the course of [two weeks]14 days, from November 21st to December 4th.
2013.12.14
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Opening Ceremony of Genetic Donguibogam held
- Medicine using traditional natural substances • Food product source technology development begins - Over 150,000,000,000 Won for 10 years of work invested to develop source technology - Opening ceremony held on November 26th at 3 p.m. in Bio & Brain Engineering Division Building The research to develop medicine and food source technology using traditional natural substances hasbegun.The opening ceremony of the “Genetic Donguibogam” business group, with KAIST Department of Bio & Brain Engineering Professor Do Heon Lee as the leader, was held on November 26th at 3 p.m. in Dream Hall, Bio & Brain Engineering Division Building, KAIST, Daejeon. The attendees of the opening ceremony included Yo Eop Im, Head of the Future Technology Department of the Ministry of Science, ICT and Future Planning and around 200 experts in science and technology industry, including the National Research Foundation of Korea, KAIST, the Korea Institute of Science and Technology, Seoul National University and Yonsei University. The business group was established to re-interpret traditional natural substances proved to be effective from experience and improve quality of life by researching its applications; and to develop integrated source technology using traditional natural substances. The group is to invest over 150,000,000,000 Won for 10 years of research to secure natural substance source technology in five stages: interpretation technology, analysis technology, verification technology, bio marker technology and human body effectiveness verification technology. Especially, the focus would be on the use of virtual body computer models and Omics* to analyse the effects of traditional natural substances mixture on human body, and to find new materials for healthcare. This research model, it is hoped, will have a new item to pioneer in the world natural substance market as well as securing a technologically competitive edge in bio industry by developing source technology that investigates the effects of traditional natural substances using cutting edge science. KAIST Department of Bio & Brain Engineering Professor and Head Do Heon Lee of the “Genetic Donguibogam” Business Group said, “We will push forward to develop source energy by integrating IT-BT technology with a computer virtual body to build a cooperation system with medicine and functional food industries.” He continued: “This will enable not only the creation of a new industry, but also customised medicine.” The 12 partners of the group include KAIST, Korea Institute of Science and Technology, Seoul National University and Yonsei University and 200 experts. The research participation area will be widened to foreign research institutes and associated companies. * Terminology Noun) Omics is an academic discipline analysing mass information on metabolism of physiological phenomena in specific cells (transcriptome, proteome and protoplast) with an integrated approach to determine vital phenomena.
2013.12.11
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KAIST Takes Steps towards a Self-Sustainable Campus
KAIST has been selected for a $45-million national smart grid initiative organized under the Ministry of Trade, Industry and Energy. Ninteen institutions will participate in the 2-year-long initiative. The consortium’s work is expected to take place from 2015 to 2017 after a review by the Ministry of Strategy and Finance. The Smart Grid Explansion Initiative which has been considered the future of electric power industry implements information and communications technology to conventional grid system to maximize energy efficiency. The ROK government has selected the Smart Grid Expansion Initiative as one of South Korea’s primary national projects and plans to implement it nationwide based on multiple demonstration projects in major cities including Jeju. KAIST plans to invest $45 million in developing systems for renewable energy power plants, efficient energy management, smart grid data, and electric vehicles to build the energy self-sustainable campus. It also hopes to contribute to fostering specialized talents and companies in energy management. Byoung-Yoon Kim, the vice-president for research at KAIST, expects that by 2017, KAIST will be able to dramatically improve its energy capacity especially during peak periods and gain energy efficiency around the campus. He hopes that the micro grid project at KAIST will set a new standard for the self-sustainable campus.
2013.12.11
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Graduate Student at KAIST Awarded Best Prize at the 9th Inside Edge
Sun-Jin Choi, a Ph. D. candidate in the Department of Materials Science and Engineering at KAIST, under the guidance of Professor Il-Doo Kim, won the best prize at the 9th Inside Edge Contest hosted by Samsung Electro-Mechanics. Choi was awarded prize money totaling fifteen million won at the award ceremony held on November 22 at the Mirae Hall at the headquarters of Samsung Electro-Mechanics in Suwon. Choi’s research, titled “Exhaled Breath Sensor Arrays for the Non-invasive and Real-time Diagnosis of Diabetes by Detection of Acetone,” was recognized for its creativity and uniqueness.The Inside Edge is an international thesis competition which was started in 2005 to encourage and support creative research and potential technological development among young scientists and engineers. Sun-Jin Choi (left) and Professor Il-Doo Kim (right).
2013.12.11
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First International Conference on Science and Technology for Society
KAIST co-organized the 2013 International Conference on Science and Technology for Society which was held on November 28 at the Grace Hall in Seoul EL-Tower. More than 300 people, including members of the Global Social Technology Advisory Board, domestic social technology experts, private companies, government officials, private citizens, and students joined the conference to discuss the roles and responsibilities of science and technology for society. R&D policies and technologies for solving social issues were introduced, and discussions were held on desirable directions for technological development. The first speaker, Yasushi Watanabe, Director of RISTEX (Research Institute of Science and Technology for Society) in Japan, introduced the importance of science and technology for society under the title “Change of R&D Paradigm for Society.” Robert Wimmer, GrAT (Center for Appropriate Technology), Vienna University of Technology in Austria, presented “Need-oriented Design & Solutions for Development.” Kiyoaki Murakami, MRI, Japan, presented “Introduction of Platinum Vision” and Robert Ries, University of Florida, U.S.A., presented “Evaluating the Social Impacts of the Built Environment Using Life Cycle Assessment.” Case studies on social enterprises and presentations on R&D for solving social problems were introduced by ICISTS (International Conference for the Integration of Science, Technology and Society), which is a student group at KAIST, National Research Foundation of Korea (NRF), Korea Institute of Machinery and Materials (KIMM), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Korea Institute of Industrial Technology (KITECH), Electronics and Telecommunication Research Institute (ETRI), and Korea Research Institute of Chemical Technology (KRICT).The conference was hosted by the Ministry of Science, ICT, and Future Planning and co-organized by NRF, KIMM, KRIBB, KITECH, ETRI and KRICT.
2013.12.11
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The key to Alzheimer disease, PET-MRI made in Korea
Professor Kyu-Sung Cho - Simultaneous PET-MRI imaging system commercialization technology developed purely from domestic technology - - Inspiring achievement by KAIST, National NanoFab Center, Sogang University, Seoul National University Hospital – Hopes are high for the potential of producing domestic products in the field of state-of-the-art medical imaging equipment that used to rely on imported products. The joint research team (KAIST, Sogang University and Seoul National University) with KAIST Department of Nuclear and Quantum Engineering Professor Kyu-Sung Cho in charge, together with National Nanofab Institution (NNFC; Director Jae-Young Lee), has developed PET-MRI simultaneous imaging system with domestic technology only. The team successfully acquired brain images of 3 volunteers with the newly developed system. PET-MRI is integrated state-of-the-art medical imaging equipment that combines the advantages of Magnetic Resonance Imaging (MRI) that shows anatomical images of the body and Position Emission Tomography (PET) that analyses cell activity and metabolism. Since the anatomical information and functional information can be seen simultaneously, the device can be used to diagnose early onset Alzheimer’s disease and is essential in biological science research, such as new medicine development. The existing equipment used to take MRI and PET images separately due to the strong magnetic field generated by MRI and combine the images. Hence, it was time consuming and error-prone due to patient’s movement. There was a need to develop PET that functions within a magnetic field to create a simultaneous imaging system. The newly developed integral PET-MRI has 3 technical characteristics: 1. PET detector without magnetic interference, 2. PET-MRI integration system, 3.PET-MRI imaging processing. The PET detector is the most important factor and accounts for half the cost of the whole system. KAIST Professor Cho and NNFC Doctor Woo-Suk Seol’s team successfully developed the Silicon Photomultiplier (amplifies light coming into the radiation detector) that can be used in strong magnetic fields. The developed sensor has a global competitive edge since it optimises semiconductor processing to yield over 95% productivity and around 10% gamma radiation energy resolving power. Sogang University Department and Electrical Engineering Professor Yong Choi developed cutting edge PET system using a new concept of electric charge signal transmission method and imaging location distinction circuit. The creativity and excellence of the research findings were recognised and hence published on the cover of Medical Physics in June. Seoul National University Hospital Department of Nuclear Medicine Professor Jae-Sung Lee developed the Silicon Photomultiplier sensor based PET imaging reconstitution programme, MRI imaging based PET imaging revision technology and PET-MRI imaging integration software. Furthermore, KAIST Department of Electrical Engineering Professor Hyun-Wook Park was responsible for the development of RF Shielding technology that enables simultaneous installation of PET and MRI and using this technology, he developed a head coil for the brain that can be connected to PET for installation. Based on the technology describe above, the joint research team successfully developed PET-MRI system for brains and acquired PET-MRI integrated brain images from 3 volunteers last June. In particular, this system has the distinct feature of a detachable PET module and MRI head coil to the existing whole body MRI, so that PET-MRI simultaneous imaging is possible with low installation cost. Professor Cho said, “We have prepared the foundation of domestic commercial PET and the system has a competitive edge in the global market of PET-MRI system technology.” He continued, “It can reduce the cost of the increasing brain related disease diagnosis, including Alzheimer’s, dramatically.” Funded by Ministry of Trade, Industry and Energy as an Industrial Foundation Technology Development Project (98 billion won in 7 years), the research applied for over 20 patents and 20 CSI theses. Figure 1.Brain phantom images from developed PET-MRI system Figure 2. Brain images from developed PET-MRI system Figure 3. Domestic PET-MRI clinical trial Figure 4. Head RF coil and PET detector inserted in MRI Figure 5. Insertion type PET detector module Figure 6. Silicon Photomultiplier sensor (Left) and flash crystal block (right) Figure7. Silicon Photomultiplier sensor Figure 8. PET detection principle
2013.11.28
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