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Professor Dongsu Han Named Program Chair for ACM CoNEXT 2020 Professor Dongsu Han from the School of Electrical Engineering has been appointed as the program chair for the 16th Association for Computing Machinery’s International Conference on emerging Networking EXperiments and Technologies (ACM CoNEXT 2020). Professor Han is the first program chair to be appointed from an Asian institution. ACM CoNEXT is hosted by ACM SIGCOMM, ACM's Special Interest Group on Data Communications, which specializes in the field of communication and computer networks. Professor Han will serve as program co-chair along with Professor Anja Feldmann from the Max Planck Institute for Informatics. Together, they have appointed 40 world-leading researchers as program committee members for this conference, including Professor Song Min Kim from KAIST School of Electrical Engineering. Paper submissions for the conference can be made by the end of June, and the event itself is to take place from the 1st to 4th of December. Conference Website: https://conferences2.sigcomm.org/co-next/2020/#!/home (END)
2020.06.02 View 8414
Universal Virus Detection Platform to Expedite Viral Diagnosis Reactive polymer-based tester pre-screens dsRNAs of a wide range of viruses without their genome sequences The prompt, precise, and massive detection of a virus is the key to combat infectious diseases such as Covid-19. A new viral diagnostic strategy using reactive polymer-grafted, double-stranded RNAs will serve as a pre-screening tester for a wide range of viruses with enhanced sensitivity. Currently, the most widely using viral detection methodology is polymerase chain reaction (PCR) diagnosis, which amplifies and detects a piece of the viral genome. Prior knowledge of the relevant primer nucleic acids of the virus is quintessential for this test. The detection platform developed by KAIST researchers identifies viral activities without amplifying specific nucleic acid targets. The research team, co-led by Professor Sheng Li and Professor Yoosik Kim from the Department of Chemical and Biomolecular Engineering, constructed a universal virus detection platform by utilizing the distinct features of the PPFPA-grafted surface and double-stranded RNAs. The key principle of this platform is utilizing the distinct feature of reactive polymer-grafted surfaces, which serve as a versatile platform for the immobilization of functional molecules. These activated surfaces can be used in a wide range of applications including separation, delivery, and detection. As long double-stranded RNAs are common byproducts of viral transcription and replication, these PPFPA-grafted surfaces can detect the presence of different kinds of viruses without prior knowledge of their genomic sequences. “We employed the PPFPA-grafted silicon surface to develop a universal virus detection platform by immobilizing antibodies that recognize double-stranded RNAs,” said Professor Kim. To increase detection sensitivity, the research team devised two-step detection process analogues to sandwich enzyme-linked immunosorbent assay where the bound double-stranded RNAs are then visualized using fluorophore-tagged antibodies that also recognize the RNAs’ double-stranded secondary structure. By utilizing the developed platform, long double-stranded RNAs can be detected and visualized from an RNA mixture as well as from total cell lysates, which contain a mixture of various abundant contaminants such as DNAs and proteins. The research team successfully detected elevated levels of hepatitis C and A viruses with this tool. “This new technology allows us to take on virus detection from a new perspective. By targeting a common biomarker, viral double-stranded RNAs, we can develop a pre-screening platform that can quickly differentiate infected populations from non-infected ones,” said Professor Li. “This detection platform provides new perspectives for diagnosing infectious diseases. This will provide fast and accurate diagnoses for an infected population and prevent the influx of massive outbreaks,” said Professor Kim. This work is featured in Biomacromolecules. This work was supported by the Agency for Defense Development (Grant UD170039ID), the Ministry of Science and ICT (NRF-2017R1D1A1B03034660, NRF-2019R1C1C1006672), and the KAIST Future Systems Healthcare Project from the Ministry of Science and ICT (KAISTHEALTHCARE42). Profile:-Professor Yoosik KimDepartment of Chemical and Biomolecular Engineeringhttps://qcbio.kaist.ac.kr KAIST-Professor Sheng LiDepartment of Chemical and Biomolecular Engineeringhttps://bcpolymer.kaist.ac.kr KAIST Publication:Ku et al., 2020. Reactive Polymer Targeting dsRNA as Universal Virus Detection Platform with Enhanced Sensitivity. Biomacromolecules (https://doi.org/10.1021/acs.biomac.0c00379).
2020.06.01 View 17112
KAIST Elected to Universities Space Research Association Membership KAIST joined the Universities Space Research Association (USRA) on May 4, and brought the Association to a total of 113 member universities. The expertise KAIST brings will broaden the Association’s collective strength in space-related science, technology, and engineering worldwide. Professor Hyosang Yoon from the Department of Aerospace Engineering will serve as the representative of KAIST to USRA. KAIST was selected by USRA’s current university members, in recognition of its significant commitment in, and contributions to, the fields of space and aerospace research. Especially, KAIST have developed Korea's first satellite, KITSAT-1 in 1992, which paved the way for space research in Korea and helped the nation strengthen technological competitiveness in that field. USRA was established in 1969 under the auspices of the National Academy of Sciences (NAS) of the United States. It is a non-profit corporation chartered to advance space-related science, technology, and engineering. USRA operates scientific institutes and facilities, and conducts other major research and educational programs, using federal funding. USRA also engages the university community and employs in-house scientific leadership, innovative research and development, and project management expertise. USRA’s President and CEO Dr. Jeffrey A. Isaacson said in his announcement, “We are delighted to welcome these two renowned universities as members. We look forward to their active engagement with, and contributions to, our Association.” President Isaacson visited KAIST on December 10 last year to discuss possible collaborations between two organizations. (END)
2020.05.29 View 5944
Professor Tek-jin Nam Elected to DSR Int’l Advisory Council Professor Tek-jin Nam from the Department of Industrial Design was elected to serve on the first International Advisory Council (IAC) of the Design Research Society (DRS). The DRS, an academic society in the field of design research, was founded in the UK in 1966 with the mission of developing and promoting design research. The IAC is newly established under the new DRS governance structure, and its members are selected from distinguished design researchers recommended by DRS members around the globe. The new IAC members will carry out various activities offered by the DRS, which include innovating design research, strengthening the design researchers’ network and developing policies to nurture new researchers.
2020.05.22 View 4477
Professor Youngchul Kim Joins Presidential Commission on Architecture Policy Professor Youngchul Kim from the Department of Civil and Environmental Engineering, who is also the Director of the Smart City Research Center at KAIST, was appointed as a commissioner of the 6th Presidential Commission on Architecture Policy on May 19. Professor Kim will contribute to coordinating and deliberating national architecture and urban development policies. He will serve a two-year term beginning this month. The Presidential Commission on Architecture Policy is made up of 30 commissioners. Nineteen members, including Professor Kim, are experts from the private sector, and the rest include the Minister of Land, Infrastructure, and Transport, the Minister for Environment, and other government officials. The non-governmental commissioners represent a diverse mixture of genders, ages, and regions for the balanced development of the nation. (END)
2020.05.21 View 5807
The 10th KINC Fusion Research Awardees The KAIST Institute for NanoCentury (KINC) recognized three distinguished researchers whose convergence studies made significant impacts. The KINC presented the 10th KINC Fusion Research Awards during a ceremony that took place at KAIST’s main campus in Daejeon on May 19. This year’s ‘best’ convergence research award went to a joint research group led by Professor Hee Tak Kim from the Department of Chemical and Biomolecular Engineering and Professor Sang Ouk Kim from the Department of Materials Science and Engineering. Their research, featured in the December 27 issue of Advanced Materials as a front cover article last year, introduced the world’s first high-energy efficiency, membraneless, flowless, zinc-bromine battery. This study, in which research professor Gyoung Hwa Jeong, postdoctoral researcher Yearin Byun, and PhD candidate Ju-Hyuck Lee took part as co-lead authors, is deemed as an example of a best practice in convergence research in which two groups’ respective expertise in the fields of carbon materials and electrochemical analysis created a synergistic effect. Professor Bumjoon Kim from the Department of Chemical and Biomolecular Engineering was also recognized for having published the most interdisciplinary research papers on polymer electronics and nanomaterials at home and abroad. Professor Hee-Tae Jung, the Director of KINC and the host of the KINC Fusion Research Awards, said, “The KINC is happy to announce the 10th awardees in nano-fusion research this year. Since convergence is crucial for making revolutionary changes, the importance of convergence studies should be recognized. Our institute will spare no effort to create a research environment suitable for convergence studies, which will be crucial for making a significant difference.” The KINC was established in June 2006 under the KAIST Institute with the mission of facilitating convergence studies by tearing down boarders among departments and carrying out interdisciplinary joint research. Currently, the institute is comprised of approximately 90 professors from 13 departments. It aims to become a hub of university institutes for nano-fusion research. (END)
2020.05.19 View 11779
Highly Efficient Charge-to-Spin Interconversion in Graphene Heterostructures Researchers present a new route for designing a graphene-based active spintronic component KAIST physicists described a route to design the energy-efficient generation, manipulation and detection of spin currents using nonmagnetic two-dimensional materials. The research team, led by Professor Sungjae Cho, observed highly efficient charge-to-spin interconversion via the gate-tunable Rashba-Edelstien effect (REE) in graphene heterostructures. This research paves the way for the application of graphene as an active spintronic component for generating, controlling, and detecting spin current without ferromagnetic electrodes or magnetic fields. Graphene is a promising spintronic component owing to its long spin diffusion length. However, its small spin-orbit coupling limits the potential of graphene in spintronic applications since graphene cannot be used to generate, control, or detect spin current. “We successfully increased the spin-orbit coupling of graphene by stacking graphene on top of 2H-TaS2, which is one of the transition metal dichalcogenide materials with the largest spin-orbit coupling. Graphene now can be used to generate, control, and detect spin current,” Professor Cho said. The Rashba-Edelstein effect is a physical mechanism that enables charge current-to-spin current interconversion by spin-dependent band structure induced by the Rashba effect, a momentum-dependent splitting of spin bands in low-dimensional condensed matter systems. Professor Cho’s group demonstrated the gate-tunable Rashba-Edelstein effect in a multilayer graphene for the first time. The Rahsba-Edelstein effect allows the two-dimensional conduction electrons of graphene to be magnetized by an applied charge current and form a spin current. Furthermore, as the Fermi level of graphene, tuned by gate voltage, moves from the valence to conduction band, the spin current generated by graphene reversed its spin direction. This spin reversal is useful in the design of low-power-consumption transistors utilizing spins in that it provides the carrier “On” state with spin up holes (or spin down electrons) and the "Off" state with zero net spin polarization at so called “charge neutrality point” where numbers of electrons and holes are equal. “Our work is the first demonstration of charge-to-spin interconversion in a metallic TMD (transition-metal dichalcogenides) and graphene heterostructure with a spin polarization state controlled by a gate. We expect that the all-electrical spin-switching effect and the reversal of non-equilibrium spin polarization by the application of gate voltage is applicable for the energy-efficient generation and manipulation of spin currents using nonmagnetic van der Waals materials,” explained Professor Cho. This study (https://pubs.acs.org/doi/10.1021/acsnano.0c01037) was supported by the National Research Foundation of Korea. Publication: Lijun Li, Jin Zhang, Gyuho Myeong, Wongil Shin, Hongsik Lim, Boram Kim, Seungho Kim, Taehyeok Jin, Stuart Cavill, Beom Seo Kim, Changyoung Kim, Johannes Lischner, Aires Ferreira, and Sungjae Cho, Gate-Tunable Reversible Rashba−Edelstein Effect in a Few-Layer Graphene/2H-TaS2 Heterostructure at Room Temperature. ACS Nano 2020. Link to download the paper: https://pubs.acs.org/doi/10.1021/acsnano.0c01037 Profile: Professor Sungjae Cho, PhD sungjae.cho@kaist.ac.kr http://qtak.kaist.ac.kr Department of Physics Korea Advanced Institute of Science and Technology (KAIST) https://www.kaist.ac.kr Daejeon 34141, Korea
2020.05.18 View 8357
Hubo Debuts as a News Anchor HUBO, a humanoid robot developed by Professor Jun-Ho Oh’s team, made its debut as a co-anchor during the TJB prime time news 8 on May 14. “Un-contact" became the new normal after Covid-19 and many business solutions are being transformed using robotics. HUBO made two news reports on contactless services using robots in medical, manufacturing, and logistics industries. HUBO 2, the second generation of HUBO, appeared as a special anchor on the local broadcasting network’s special program in celebration of its 25th anniversary. HUBO is the champion of the 2015 DARPA Robotics Challenge held in the USA. Its FX-2 riding robot also participated in the Olympic torch relay during the 2018 PyeongChang Winter Olympics. Click here to watch a full video of HUBO anchoring the news. (END)
2020.05.14 View 9894
Dr. Dong-Hyun Cho at KARI Receives the 16th Jeong Hun Cho Award Dr. Dong-Hyun Cho, a senior researcher at the Korea Aerospace Research Institute (KARI), was honored as the recipient of the 16th Jeong Hun Cho Award. The award recognizes young scientists in the field of aerospace engineering. Dr. Cho earned his MS and PhD degrees from the KAIST Department of Aerospace Engineering in 2012, and served as a researcher at the Satellite Technology Research Center (SaTReC) at KAIST, before joining the Future Convergence Research Division at KARI. He won this year’s award and received 25 million KRW in prize money. Jeong Hun Cho, who was a PhD candidate in the Department of Aerospace Engineering at KAIST, passed away in a tragic lab accident in May 2003 and was awarded an honorary doctorate posthumously. His family endowed the award and scholarship in his memory. Since 2005, the scholarship has selected three young scholars every year who specialize in aerospace engineering from Cho’s alma maters of KAIST, Korea University, and Kongju National University High School. Dr. Dong-Hyun Cho was selected as this year’s awardee in recognition of his studies on the development and operation of KARISMA, a comprehensive software package for space debris collision risk management. Dr. Cho built a terrestrial testbed and produced a model for the development of a space debris elimination algorithm. He published six papers in SCI-level journals and wrote 35 symposium papers in the field of space development. He also applied or registered approximately 40 patents both in Korea and internationally. The Award Committee also selected three students as scholarship recipients: PhD candidate Yongtae Yun from the Department of Aerospace Engineering at KAIST received 4 million KRW, MS-PhD candidate Haun-Min Lee from the School of Mechanical Engineering at Korea University received 4 million KRW, and Seonju Yim from Kongju National University High School received 3 million KRW. (END)
2020.05.13 View 8941
Simple Molecular Reagents to Treat Alzheimer’s Disease - Researchers report minimalistic principles for designing small molecules with multiple reactivities against dementia. - Sometimes the most complex problems actually have very simple solutions. A group of South Korean researchers reported an efficient and effective redox-based strategy for incorporating multiple functions into simple molecular reagents against neurodegenerative disorders. The team developed redox-active aromatic molecular reagents with a simple structural composition that can simultaneously target and modulate various pathogenic factors in complex neurodegenerative disorders such as Alzheimer’s disease. Alzheimer’s disease is one of the most prevalent neurodegenerative disorders, affecting one in ten people over the age of 65. Early-onset dementia also increasingly affects younger people. A number of pathogenic elements such as reactive oxygen species, amyloid-beta, and metal ions have been suggested as potential causes of Alzheimer’s disease. Each element itself can lead to Alzheimer’s disease, but interactions between them may also aggravate the patient’s condition or interfere with the appropriate clinical care. For example, when interacting with amyloid-beta, metal ions foster the aggregation and accumulation of amyloid-beta peptides that can induce oxidative stress and toxicity in the brain and lead to neurodegeneration. Because these pathogenic factors of Alzheimer’s disease are intertwined, developing therapeutic agents that are capable of simultaneously regulating metal ion dyshomeostasis, amyloid-beta agglutination, and oxidative stress responses remains a key to halting the progression of the disease. A research team led by Professor Mi Hee Lim from the Department of Chemistry at KAIST demonstrated the feasibility of structure-mechanism-based molecular design for controlling a molecule’s chemical reactivity toward the various pathological factors of Alzheimer’s disease by tuning the redox properties of the molecule. This study, featured as the ‘ACS Editors’ Choice’ in the May 6th issue of the Journal of the American Chemical Society (JACS), was conducted in conjunction with KAIST Professor Mu-Hyun Baik’s group and Professor Joo-Young Lee’s group at the Asan Medical Center. Professor Lim and her collaborators rationally designed and generated 10 compact aromatic molecules presenting a range of redox potentials by adjusting the electronic distribution of the phenyl, phenylene, or pyridyl moiety to impart redox-dependent reactivities against the multiple pathogenic factors in Alzheimer’s disease. During the team’s biochemical and biophysical studies, these designed molecular reagents displayed redox-dependent reactivities against numerous desirable targets that are associated with Alzheimer’s disease such as free radicals, metal-free amyloid-beta, and metal-bound amyloid-beta. Further mechanistic results revealed that the redox properties of these designed molecular reagents were essential for their function. The team demonstrated that these reagents engaged in oxidative reactions with metal-free and metal-bound amyloid-beta and led to chemical modifications. The products of such oxidative transformations were observed to form covalent adducts with amyloid-beta and alter its aggregation. Moreover, the administration of the most promising candidate molecule significantly attenuated the amyloid pathology in the brains of Alzheimer’s disease transgenic mice and improved their cognitive defects. Professor Lim said, “This strategy is straightforward, time-saving, and cost-effective, and its effect is significant. We are excited to help enable the advancement of new therapeutic agents for neurodegenerative disorders, which can improve the lives of so many patients.” This work was supported by the National Research Foundation (NRF) of Korea, the Institute for Basic Science (IBS), and the Asan Institute for Life Sciences. Image credit: Professor Mi Hee Lim, KAIST Image usage restrictions: News organizations may use or redistribute this image, with proper attribution, as part of the news coverage of this paper only. Publication: Kim, M. et al. (2020) ‘Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia.’ Journal of the American Chemical Society (JACS), Volume 142, Issue 18, pp.8183-8193. Available online at https://doi.org/10.1021/jacs.9b13100 Profile: Mi Hee Lim Professor miheelim@kaist.ac.kr http://sites.google.com/site/miheelimlab Lim Laboratory Department of Chemistry KAIST Profile: Mu-Hyun Baik Professor mbaik2805@kaist.ac.kr https://baik-laboratory.com/ Baik Laboratory Department of Chemistry KAIST Profile: Joo-Yong Lee Professor jlee@amc.seoul.kr Asan Institute for Life Sciences Asan Medical Center (END)
2020.05.11 View 12751
Professor Sukyung Park Named Presidential Science and Technology Adviser Professor Sukyung Park from the Department of Mechanical Engineering was appointed as the science and technology adviser to the President Jae-in Moon on May 4. Professor Park, at the age of 47, became the youngest member of the president’s senior aide team at Chong Wa Dae. A Chong Wa Dae spokesman said on May 4 while announcing the appointment, “Professor Park, a talent with a great deal of policymaking participation in science and technology, will contribute to accelerating the government’s push for science and technology innovation, especially in the information and communications technology (ICT) sector.” Professor Park joined KAIST in 2004 as the first female professor of mechanical engineering. She is a biomechanics expert who has conducted extensive research on biometric mechanical behaviors. Professor Park is also a member of the KAIST Board of Trustees. Before that, she served as a senior researcher at the Korea Institute of Machinery and Materials (KIMM) as well as a member of the Presidential Advisory Council on Science and Technology. After graduating from Seoul Science High School as the first ever two-year graduate, Professor Park earned a bachelor and master’s degrees in mechanical engineering at KAIST. She then finished her Ph.D. from the University of Michigan. (END)
2020.05.06 View 11201
Breastfeeding Helps Prevent Mothers from Developing Diabetes after Childbirth A team of South Korean researchers found that lactation can lower the incidence and reduce the risk of maternal postpartum diabetes. The researchers identified that lactation increases the mass and function of pancreatic beta cells through serotonin production. The team suggested that sustained improvements in pancreatic beta cells, which can last for years even after the cessation of lactation, improve mothers’ metabolic health in addition to providing health benefits for infants. Pregnancy imposes a substantial metabolic burden on women through weight gain and increased insulin resistance. Various other factors, including a history of gestational diabetes, maternal age, and obesity, further affect women’s risk of progressing to diabetes after delivery, and the risk of postpartum diabetes increases more in women who have had gestational diabetes and/or repeated deliveries. Diabetes-related complications include damage to blood vessels, which can lead to cardiovascular and cerebrovascular diseases such as heart attack and stroke, and problems with the nerves, eyes, kidneys, and many more. Since diabetes can pose a serious threat to mothers’ metabolic health, the management of maternal metabolic risk factors is important, especially in the peripartum period. Previous epidemiological studies have reported that lactation reduces the risk of postpartum diabetes, but the mechanisms underlying this benefit have remained elusive. The study, published in Science Translational Medicine on April 29, explains the biology underpinning this observation on the beneficial effects of lactation. Professor Hail Kim from the Graduate School of Medical Science and Engineering at KAIST led and jointly conducted the study in conjunction with researchers from the Seoul National University Bundang Hospital (SNUBH) and Chungnam National University (CNU) in Korea, and the University of California, San Francisco (UCSF) in the US. In their study, the team observed that the milk-secreting hormone ‘prolactin’ in lactating mothers not only promotes milk production, but also plays a major role in stimulating insulin-secreting pancreatic beta cells that regulate blood glucose in the body. The researchers also found that ‘serotonin’, known as a chemical that contributes to wellbeing and happiness, is produced in pancreatic beta cells during lactation. Serotonin in pancreatic beta cells act as an antioxidant and reduce oxidative stress, making mothers’ beta cells healthier. Serotonin also induces the proliferation of beta cells, thereby increasing the beta cell mass and helping maintain proper glucose levels. The research team conducted follow-up examinations on a total of 174 postpartum women, 85 lactated and 99 non-lactated, at two months postpartum and annually thereafter for at least three years. The results demonstrated that mothers who had undergone lactation improved pancreatic beta cell mass and function, and showed improved glucose homeostasis with approximately 20mg/dL lower glucose levels, thereby reducing the risk of postpartum diabetes in women. Surprisingly, this beneficial effect was maintained after the cessation of lactation, for more than three years after delivery. Professor Kim said, “We are happy to prove that lactation benefits female metabolic health by improving beta cell mass and function as well as glycemic control.” “Our future studies on the modulation of the molecular serotonergic pathway in accordance with the management of maternal metabolic risk factors may lead to new therapeutics to help prevent mothers from developing metabolic disorders,” he added. This work was supported by grants from the National Research Foundation (NRF) and the National Research Council of Science and Technology (NST) of Korea, the National Institutes of Health (NIH), the Larry L. Hillblom Foundation, and the Health Fellowship Foundation. Image credit: Professor Hail Kim, KAIST Image usage restrictions: News organizations may use or redistribute this image, with proper attribution, as part of news coverage of this paper only. Publication: Moon, J. H et al. (2020) ‘Lactation improves pancreatic β cell mass and function through serotonin production.’ Science Translational Medicine, 12, eaay0455. Available online at https://doi.org/10.1126/scitranslmed.aay0455 Profile: Hail Kim, MD, PhD hailkim@kaist.edu Associate Professor Graduate School of Medical Science and Engineering (GSMSE) Korea Advanced Institute of Science and Technology (KAIST) Profile: Hak Chul Jang, MD, PhD janghak@snu.ac.kr Professor Division of Endocrinology and Metabolism Seoul National University Bundang Hospital (SNUBH) President Korean Diabetes Association Profile: Joon Ho Moon, MD, PhD moonjoonho@gmail.com Clinical Fellow Division of Endocrinology and Metabolism SNUBH Profile: Hyeongseok Kim, MD, PhD hskim85kor@gmail.com Assistant Professor Chungnam National University (CNU) Profile: Professor Michael S. German, MD Michael.German@ucsf.edu Professor Diabetes Center University of California, San Francisco (UCSF) (END)
2020.04.29 View 16144

KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea T.042-350-2114 F.042-350-2210(2220)