IP
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The thermal fluctuation and elasticity of cell membranes, lipid vesicles, interacting with pore-forming peptides were reported by a research team at KAIST.
A research team from KAIST, consisted of Sung-Min Choi, Professor of Nuclear and Quantum Engineering Department, and Ji-Hwan Lee, a doctoral student in the Department, published a paper on the “thermal fluctuation and elasticity of lipid vesicles interacting with pore-forming peptides.” The paper was carried by Physical Review Letters, an internationally renowned peer-review journal on physics on July 16, 2010.
Cell membranes, which consist of lipid bilayers, play important roles in cells as barriers to maintain concentrations and matrices to host membrane proteins. During cellular processes such as cell fission and fusion, the cell membranes undergo various morphological changes governed by the interplay between protein and lipid membranes. There have been many theoretical and experimental approaches to understand cellular processes driven by protein-lipid membrane interactions. However, it is not fully established how the membrane elastic properties, which play an important role in membrane deformation, are affected by the protein-membrane interactions.
Antimicrobial peptides are one of the most common examples of proteins that modify membrane morphology. While the pore-forming mechanisms of antimicrobial peptides in lipid bilayers have been widely investigated, there have been only a few attempts to understand the mechanisms in terms of membrane elastic properties. In particular, the effects of pore formation on the membrane fluctuation and elastic properties, which provide key information to understand the mechanism of antimicrobial peptide activity, have not been reported yet. The research team reports the thermal fluctuation and elasticity of lipid vesicles interacting with pore-forming peptides, which were measured by neutron spin-echo spectroscopy.
The results of this study are expected to pay an important role in understanding the elastic behavior and morphological changes of cell membranes induced by protein-membrane interactions, and may provide new insights for developing new theoretical models for membrane fluctuations which include the membrane mediated interaction between protein patches.
(a) (b)
Figure
(a) Schematics for bound melittin and pores in lipid bilayers
(b) P NMR signal ratio (with/without Mn2+) of DOPC LUV-melittin vs P/L at 30˚C. The dashed line is a guide for eyes.
2010.07.23 View 12494 -
A stream of generous donations to KAIST continues to grow.
Yi-Won Oh is nothing but an ordinary person who lives in Seoul. Ever since retirement, she has looked into ways to donate her savings for a bigger cause that will benefit the people in need and the nation as a whole.
On the inauguration day of President Nam Pyo Suh who took his second term in office, Ms. Oh joined the ceremony and pledged to donate her savings to KAIST, which amounted to 10 billion won.
“I’ve always thought that the best way for our country to become a developed nation that lacks natural resources and has a small land is to develop science and technology by producing excellent manpower through a quality education. I talked to President Suh a couple of times, and we shared our common belief that the future of our nation hinges on the advancement of science and technology in Korea,” said Ms. Oh.
She added, “I support for President Suh’s vision and leadership, who has brought reformative and innovative changes to KAIST. I have no doubt that KAIST will become a leading research university in the world and play an important role in the development of our nation. It is indeed my pleasure that I can make announcement to donate my money to KAIST on the day President Suh is assigned to lead such a distinguished university one more time.”
KAIST plans to create and operate a fund dubbed “Yi-Won Oh Scholarship and Grant for Young Chair Professors.” Through the fund, talented students suffering financial difficulties and promising, young professors will have a richer opportunity to study and research.
2010.07.21 View 10201 -
"The 2010 Artificial Intelligence Robot War Competition" begins to receive applications
[Event Notice]
“The 2010 Artificial Intelligence Robot War Competition” begins to receive applications
A good opportunity to gauge the intelligence of your robots
“The 2010 Artificial Intelligence (AI) Robot War Competition” will be held in October 2010, and the Competition has been receiving applications from contestants since April 1st. The deadline for the application will be May 31st, 2010.
Qualified contestants must be a minimum of two, but less than six, team members, and they will compete in one of the two fields: System on Chip (SoC) Taekwon Robot and Humanoid Robot (HURO). Winners will be decided based on the intelligence capabilities presented by a robot’s platform that mimics key functions of the human brain.
SoC Taekwon Robot will compete against one another by using a camera installed on its head to recognize visual images, locations, distances, and gestures of the other competing robot.
HURO competition is a new entry begun this year, and winners will be determined in accordance with the robot’s ability to perform given missions and fights. Missions are to go through a track installed with obstacles, recognize colors and shapes of barriers, and knock down barriers to earn scores. Fighting will be performed in the form of a Korean martial art, Tae-kwon-do.
The Korean government has nominated Robotics as one of the key growth engines to develop IT industry and Korean economy. Robotics converge many of different engineering fields, such as machinery, materials, components, and embedded software. In particular, the SoC is an essential technology for Korea to continuously take lead in the semi-conductor industry in the world, which is an important element for robotics.
SoC stands for System on Chip, an integrated chip that assembles various chips and components to be fabricated together on a single chip, instead of building them on a circuit board. The SoC technology has advantages of higher performance, smaller space requirements, lower memory requirements, higher system reliability, and lower consumer costs.
An artificial intelligence SoC robot is autonomous because it can adapt itself to changes in various environments and reach a given goal without constantly receiving external orders.
For details of the event, please refer to the website of www.socrobotwar.org.
2010.04.06 View 13287 -
KAIST Research Team Identified Promising New Source to Obtain Stem Cells
KAIST Research Team Identified Promising New Source to Obtain Stem Cells
A research team at KAIST led by Professor Gou-Young Koh, M.D. and Ph.D., of the Department of Biological Sciences, has found evidence that fat tissue, known as adipose tissue, may be a promising new source of valuable and easy-to-obtain regenerative cells called hematopoietic stem and progenitor cells (HSPCs).
HSPCs are adult stem cells that have the ability to generate and develop into many different kinds of cells. They are now used to repair damaged tissues and are being studied for their potential to treat a vast array of chronic and degenerative conditions such as leukemia. Mostly found in bone marrow but with a limited quantity, HSPCs are hard to cultivate in vitro, thus becoming an obstacle to use them for research and therapeutic purposes.
Within the adipose tissue is a special cell population known as the stromal vascular fraction (SVF), which share similar properties to those in the bone marrow. Cells in the bone marrow and SVF have the ability to differentiate into several cell types. In addition, both adipose and bone marrow offer similar environments for optimal stem cell growth and reproduction.
Given the fact that adipose and bone marrow tissues share similar properties, Dr. Koh and his team conducted a research, injecting granulocyte colony-stimulating factor (G-CSF), a growth hormone used to encourage the development of stem cells, into an adipose tissue of a mouse whose bone marrow is damaged. As a result, the team has found that the SVF derived from adipose tissue contains functional HSPCs capable of generating hematopoietic (blood-forming) cells to repair the damaged bone morrow.
The Ministry of Education, Science and Technology nominated the KAIST research as one of its sponsoring 21st Century Frontier R&D Programs. Director Dong-Wook Kim of Stem Cell Research Center (SCRS) that oversees the KAIST team expressed a possibility to use the adipose tissue as an alternative source to obtain stem cells for regeneration medicine.
Dr. Koh also said, “It’s been a well known method to extract HSPCs from the bone morrow or blood, but it’s the first time to identify adipose tissue, before considered useless, as a new possible supplier for functional and transplantable HSPCs.”
The study results have received an important recognition from the academia—the American Society of Hematology published the research as a main article in its official journal, Blood, for the February 4th, 2010 issue, which is the most citied peer-reviewed publication in the field.
2010.02.05 View 12703
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Master of Science in Intellectual Property: First Class Starts on Saturday, February 6, 2010
Newly Established, Postgraduate Course for Master of Science in Intellectual Property
First class starts on February 6th, 2010
In conjunction with Korean Intellectual Property Office (KIPO), KAIST has established a new postgraduate course for a master of science in intellectual property (IP). 41 students have enrolled the course, and its first class will begin February 6th, 2010. With a diverse professional background, the first-year students came from private businesses, IP service industry, and public organizations.
Globally well-known companies—Samsung Electronics, LG Electronics, and the Pohang Iron and Steel Company (POSCO)—and mid-sized companies have offered scholarships to support the new M.S. Program. Business and industry in Korea have recognized the increasingly important role of intellectual property in a modern economy and showed a strong interest in developing workforce specialized in subjects such as, but not limited to, patent law, copyright and designs law, trade mark law, unfair competition, anti-trust law, competition law, and trade secret law.
Prosecutor Chan-Gi Na from Seoul Central District Prosecutor’s Office said, “I’ve applied for the master program at KAIST because I wanted to learn more about intellectual property in greater depth. Through the coursework, I hope to enhance my knowledge on the subjects and use it for the protection of Koreans’ IP related rights and the development of our nation’s IP industry.”
Assistant Manager Jin-Hong Bae from Samsung Securities, Inc. said, “Since the capital market law becomes effective, the need for developing new financial products or services in our finance market has rapidly grown. We no longer can make our financial products by simply copying or ripping off ideas from others. It’s a must practice, not an option, to set up a system under which we are able to protect our IPs.”
“I would like to become an expert in our finance market, who really knows how to commercialize intellectual property assets into benefits, so any know-hows or ideas accumulated from years of working in the field can be registered and protected,” added Mr. Bae.
KAIST’s Mater Program for intellectual property is designed for engineers who wish to acquire the skills required to play a leading role in the field. These engineers, KAIST anticipates, will establish and execute business strategies to protect intellectual property, generate added values for a company, and effectively respond against patent related claims.
The intellectual property will seize up to 90% of business values to be generated in the 21st century. KAIST has long foreseen the need for training top-notch engineers in intellectual property. Combined with multidisciplinary approach to engineering, law, and management, the new M.S. Program will provide students with a variety form of classes to assist them in getting a practical knowledge as needed based on their interests and career aspirations. Examples of the classes are workshops on the change in technology trends—i.e., information technology (IT), environmental technology (ET), and bio technology (BT); standardization of intellectual property and value assessment; and patent law related claims.
“All professors involved in the course are experts who are equipped with hands-on experiences in working on intellectual property for a long time at government agencies, companies, and law firms,” Professor Chul-Ho Kim, responsible for overseeing the entire program, said.
He also expressed his confidence that “We have set up an academic system to induct highly qualified professionals and engineers, capable of handling all aspects of intellectual property related issues, into work places. Our coursework encompasses technology, research and development (R&D), and management, and students who complete the program will be ready to tackle down any intellectual property matters in the 21st century.”
Freshmen convocation for the IP M.S. Program is scheduled on February 20th at KAIST, and President Nam Pyo Suh and Commissioner Jung-Sik Koh of Korean Intellectual Property (KIPO) will attend the event.
2010.02.04 View 13957
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Opening Ceremony Held on February 3, 2010 for Intellectual Property Training Center
KAIST Opened Training Center for Young Entrepreneurs
Commissioner Jung-Sik Koh of Korean Intellectual Property Office (KIPO) and KAIST faculty members including Soon-Hong Jang, Vice President of Operations and Kwang-Hyung Lee, Dean of Academic Affairs Office, joined an opening ceremony held on February 3rd, 2010 to launch a training center for the next generation entrepreneurs who will lead the intellectual property (IP) industry in Korea.
The training center was built in cooperation with KIPO to educate and support young entrepreneurs and prepare them to become tomorrow’s IP business leaders like Bill Gates of Microsoft and Google’s founders, Larry Page and Sergey Brin.
Going through a vigorous selection process, a total of 101 students (51 for intermediate and 50 for advanced level) were chosen last December for an orientation program that will begin February 3rd and continue through February 5th. In addition to the training center at KAIST, KIPO supported to launch another training center at the Pohang University of Science and Technology (POSTECH), which has been up and running since January 27th, 2010.
2010.02.04 View 14096 -
KAIST to Join Forces with Northwestern School of Law in MIP Program
KAIST has agreed to collaborate in its Master of Intellectual Property (MIP) program with Northwestern University School of Law, the university authorities said on Wednesday (Nov. 11).
KAIST President Nam-Pyo Suh and Northwestern Univ. School of Law Dean David Van Zandt signed a memorandum of understanding for the establishment of the certificate and degree programs of the Anglo-American law in February 2010, at the president"s office Wednesday.
The latest agreement represents an expansion of the existing KAIST-Northwestern Executive LLM program that the two schools have successfully operated for the past eight years. It is aimed at boosting KAIST"s global intellectual property capabilities at a time when the strategic management of intellectual properties and capabilities to deal with international intellectual property disputes are gaining growing importance.
The newly-established two-year, six-semester program is designed to offer a certificate program in the Anglo-American and intellectual property laws to make students better armed with legal knowledge in a competitive global environment.
Northwestern University School of Law is regarded as one of the top law schools in the United States. American law schools are better positioned than any other institutions to prepare students to move from domestic to international practice in today"s complex global economy.
LLM is Latin for Legum Magister, signifying Master of Laws
. course and neto ba ... signing an agreement to run a joint masters degree program at the KAIST campus in Seou
2009.11.19 View 13146 -
KAIST, CJ Sign MOU for Joint Research in Fundamental Technologies
KAIST and CJ Corporation, Korea"s leading foodstuff maker, have reached an agreement for an enhanced industry-academy cooperation in the biotechnology area, the university authorities said on Tuesday (Nov. 10).
KAIST President Nam-Pyo Suh signed a memorandum of understanding with Kim Jin-soo, CEO of CJ, at the KAIST campus on Tuesday (Nov. 10).
Under the agreement, KAIST and CJ will cooperate in nurturing elite research manpower and conducting joint researches in fundamental technologies. Specifically, CJ researchers will suggest research subjects linked with doctorate programs to KAIST, and once these subjects are accepted by KAIST, CJ researchers will conduct research under the guidance of KAIST professors to get doctorate degrees. All the costs including research expenses incurred during the program will be provided by CJ.
The agreement also calls for CJ to provide funding for the research subjects it selected among the ones suggested by KAIST"s biotechnology professors.
CJ CEO Jin-Soo Kim said: "Through the joint researches with KAIST which has the highest research capabilities, CJ can strengthen basic research capabilities and secure elite research manpower. We hope that the KAIST-CJ partnership will become a successful model for cooperation between industry and academia."
2009.11.11 View 12423 -
KAIST's Mobile Harbor Program Attracts Two Corporate Investments
KAIST-developed Mobile Harbor Program has attracted investments from Korea"s two big-name industrial corporations, university authorities said on Monday (Oct. 19).
KAIST has recently signed an agreement with Hyundai Wia Corp., a machine parts supplier, to collaborate in the researches of the mobile harbor programs and commercialization. Under the agreement, Hyundai WIA will invest a total of 7.5 billion won in the program for two years starting from January 2010.
KAIST has also received a letter of intent from the Daewoo Shipbuilding & Marine Engineering Co. on investing 20 billion won in the commercialization of the project.
The Mobile Harbor Program is designed to create mobile units that can go out to the ship which are anchored off-shore and unload the cargo and take it to where it is needed. It is aimed at overcoming the shortcomings of the current maritime container transportation systems. Container ships are getting larger and larger, requiring deep waters, large and complex loading and unloading systems, and major investments in facilities.
Prof. Byung-Man Kwak, leader of the program"s R&D team, said: "With the investment from two global industrial companies, the program has gained a crucial momentum. The development of the program is expected to help Korea to become a global leader in marine transportation and maintain its supremacy in shipbuilding."
2009.10.20 View 15940 -
KAIST Undergraduates Open Four-Day International Conference
The ICISTS-KAIST, an annual international conference organized by KAIST undergraduate students, opened on Thursday (Aug. 20) at the KAIST"s main campus in Daejeon.
The 2009 ICISTS (International Conference for the Integration of Science and Technology into Society) drew around 200 experts and students from 44 countries. Since its inception in 2005 to promote discourse on important science and technology issues affecting modern society, the conference has served as an opportunity for academic networking among students in various parts of the world.
The four-day conference consists of lectures, open discussions among lecturers and students, field trips to help students to understand actual applications, and team projects.
This year"s conference offers three workshops under the themes of "Climate Change: Merging Technology and Policy for Green Solutions"; "Human-Computer Interaction: Designing Computer System for Intuitive Human Access"; and "Nano Clinic: Breakthrough in Conquering Disease."
Lectures by invited experts in various scientific fields will help broaden students" perspectives particularly from interdisciplinary viewpoints, said an organizer of the conference.
2009.08.28 View 15300
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U.S. and Korean Researchers Unveil Newest Research Team Member: Jaemi the Humanoid
- Project aims to enable humanoids to interact with people and their environment
June 1, 2009-- A Drexel University-led research team late last week unveiled the newest, most central member of its collaboration with a team of Korean researchers: Jaemi, a humanoid (HUBO). Jaemi HUBO embodies efforts to advance humanoid development and enhance the concept of human-robotic interaction. The project"s goal is to enable humanoids to interact with their environment, and enhancement plans include enabling the humanoid to move over rugged terrain, in unstructured environments and to interact socially with humans and handle objects.
The five-year project, funded through the National Science Foundation (NSF) Partnership for International Research and Education (PIRE) program, seeks transformative models to catalyze discovery through international research collaboration and train U.S. students and junior researchers to effectively think and work in global teams.
"The field of robotics is among the top 10 technology areas considered engines for economic growth. Korea understands this and is aggressively pursuing robotics. To stay competitive, the U.S. must do the same," said Mark Suskin, acting deputy director of NSF"s Office of International Science and Engineering. "NSF"s PIRE program and this robotics collaboration in particular, enable the U.S. to capitalize on research in other countries and remain competitive."
The PIRE research team is composed of researchers at The University of Pennsylvania, Colby College, Bryn Mawr College and Virginia Tech in the United States; and Korea Advanced Institute of Science and Technology (KAIST), Korea University and Seoul National University in Korea.
The team obtained a version of KAIST"s HUBO humanoid, which it named Jaemi HUBO and decided to house it at Drexel University. KAIST HUBO lab has become a model of cutting advance humanoid research by relatively small teams working on tight budgets.
KAIST excels in humanoid leg and body design, biped gait (walking, running, kicking), balance (modeling and control system design), and hardware integration. U.S. robotics researchers tend to enjoy an edge in locomotion over rugged, unstructured terrain; manipulation/grasping; cognition, perception and human-robot interaction; and vision (image, understanding, navigation).
This collaboration of American and Korean researchers will seek to draw on the expertise of each researcher and take Jaemi HUBO to the next level of development--that is, to improve Jaemi"s capabilities to navigate and manipulate objects and interact with people in unstructured environments. Such capabilities demand information technologies like cognition, perception and networking areas. Targeted enhancement features include a capability to move over rugged terrain and in unstructured environments and to handle objects and interact socially with humans.
Jaemi HUBO will also educate the American public, particularly young people, about the science of robotics. This education process began at the Please Touch Museum in Philadelphia on May 28, 2009, when Jaemi HUBO was unveiled and introduced to a crowded audience of children and a few adults. Neither male nor female,Jaemi connected with the children, boys and girls alike. Guided by a Drexel University graduate student, Jamei moved, spoke, danced, shook hands and lead the children in a game of Simon Says. Such access to Jaemi HUBO starkly contrasts with that afforded by other high-profile humanoids that are often protected trade secrets, largely inaccessible to the public.
Museum curators are pleased to have had Jaemi visit and entertain kids during the weekend. "At the Please Touch Museum, we promote learning through a variety of senses," said J. Willard Whitson,the museum"s vice president for exhibits and education. "A humanoid not only embodies our goal of building layers of knowledge in young people, but Jaemi helps all of us celebrate the playful side of technology."
Jaemi HUBO is now at its permanent home at Drexel University, from which travel and guest appearances may be arranged by appointment. Journalists interested in meeting and interviewing Jaemi HUBO and other research team members are encouraged to contact Lisa-Joy Zgorski at lisajoy@nsf.gov. (Press Release of U.S. National Science Foundation)
2009.06.19 View 15123 -
KAIST Senior Wins Prizes at International Design Contests
Sung-Joon Kim, a senior at the Department of Industrial Design, KAIST, has recently won the highest prize at the iF Communication Design Award held in Hanover, Germany, university officials said on Monday (June 3).
The prizewinning work entitled "1/2 PROJECT" introduces a donation system in which a customer buys a bottle of drink, for example, containing only a half of its price value and donate the remaining half of the value. The work which was created as part of the Samsung Design Membership was also awarded a silver prize at the International Design Excellence Awards (IDEA) of the United States.
Award ceremonies of the two prizes are scheduled for in Muenchen in August and in Miami in September, respectively.
"The design project is aimed at making donation a part of everyday life by teaming up with big-name beverage makers," said Kim.
iF Communication Design Award and the IDEA are among the world"s three leading international design competitions. The other one is the Red Dot Design Award presented in Essen, Germany.
Early this year, Kim, leading a team, presented a portable life saving equipment called "Rescue Stick" to the two competitions and won high honors.
2009.06.05 View 14590