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KAIST to Host the 2017 AI World Cup in November
KAIST, the birthplace of the Robot World Cup in 1996, now presents a new technology matchup, the AI World Cup this November, which will be held at KAIST. The event is being organized by the Machine Intelligence and Robotics Multi-Sponsored Research and Education Platform (MIR-MSREP) of KAIST. The online, simulated AI soccer game, based on rolling updates, will be a draw for avid online gamers and tech-savvy university students from around the nation.
The tournament is comprised of three events: ▲A 5 on 5 AI soccer match to be played after self-learning using AI technology in an online simulation environment ▲Commentary in which online soccer videos are analyzed and commented on, and ▲Game reporters who will write articles on online soccer event results.
The participants will undergo a month-long online practice period in October and compete in preliminary matches from November 1 through 24. The top teams that scored the highest accumulated points will compete in the finals on December 1. In the finals, each team’s AI technology implementation method will be evaluated to select the final winning team. To ensure a successful event, KAIST will host a briefing session for participants on July 28.
Technological prowess and early exposure to AI accumulated at KAIST led to the launching of this tournament. Professor Jong-Hwan Kim, the chair of the Organizing Committee of the AI World Cup, hosted the first ever Robot World Cup back in 1996. His concept has now evolved into the emerging technology of AI and the members of the Organizing Committee encompass the professors from the various departments of electrical engineering, computing, industrial and systems engineering, aerospace engineering, civil and environmental engineering, and the graduate schools of Green Transportation, Cultural Technology, and Science and Technology Policy.
In particular, ongoing convergence research initiatives incorporating AI into a wide arrays of disciplines such as bio, nano, and IT, played a crucial role for making this AI World Cup happen. Professor Kim said, “The winner of this year’s competition will be awarded a certificate and a small gift. In 2018, we aim to expand the event to an international scale by allowing international teams.”
Any undergraduate or graduate student in Korea can apply to participate in the ‘AI World Cup 2017’. KAIST will host a public trial event during the ‘Open KAIST’ event period to be held November 2-3 to help participating students understand the event better. ‘Open KAIST’ allows the general public to personally visit and experience what goes on in engineering departments and laboratories on the KAIST main campus. It is hosted by the College of Engineering every two years and is the largest event hosted by KAIST.
To participate in the ‘AI World Cup 2017,’ teams consisting of Korean undergraduates or graduate students can fill out application forms and submit them by September 30 on http://mir.kaist.ac.kr .
2017.07.14 View 12723 -
Observation of the Phase Transition of Liquid Crystal Defects
KAIST researchers observed the phase transition of topological defects formed by liquid crystal (LC) materials for the first time.
The phase transition of topological defects, which was also the theme of the Nobel Prize for Physics in 2016, can be difficult to understand for a layperson but it needs to be studied to understand the mysteries of the universe or the underlying physics of skyrmions, which have intrinsic topological defects.
If the galaxy is taken as an example in the universe, it is difficult to observe the topological defects because the system is too large to observe some changes over a limited period of time. In the case of defect structures formed by LC molecules, they are not only a suitable size to observe with an optical microscope, but also the time period in which the phase transition of a defect occurring can be directly observed over a few seconds, which can be extended to a few minutes. The defect structures formed by LC material have radial, circular, or spiral shapes centering on a singularity (defect core), like the singularity that was already introduced in the famous movie "Interstellar,” which is the center point of black hole.
In general, LC materials are mainly used in liquid crystal displays (LCDs) and optical sensors because it is easy to control their specific orientation and they have fast response characteristics and huge anisotropic optical properties. It is advantageous in terms of the performance of LCDs that the defects of the LC materials are minimized. The research team led by Professor Dong Ki Yoon in the Graduate School of Nanoscience and Technology did not simply minimize such defects but actively tried to use the LC defects as building blocks to make micro- and nanostructures for the patterning applications. During these efforts, they found the way to directly study the phase transition of topological defects under in-situ conditions.
Considering the LC material from the viewpoint of a device like a LCD, robustness is important. Therefore, the LC material is injected through the capillary phenomenon between a rigid two-glass plate and the orientation of the LCs can be followed by the surface anchoring condition of the glass substrate. However, in this conventional case, it is difficult to observe the phase transition of the LC defect due to this strong surface anchoring force induced by the solid substrate.
In order to solve this problem, the research team designed a platform, in which the movement of the LC molecules was not restricted, by forming a thin film of LC material on water, which is like oil floating on water. For this, a droplet of LC material was dripped onto water and spread to form a thin film. The topological defects formed under this circumstance could show the thermal phase transition when the temperature was changed. In addition, this approach can trace back the morphology of the original defect structure from the sequential changes during the temperature changes, which can give hints to the study of the formation of topological defects in the cosmos or skyrmions.
Prof. Yoon said, “The study of LC crystal defects itself has been extensively studied by physicists and mathematicians for about 100 years. However, this is the first time that we have observed the phase transition of LC defects directly.” He also added, "Korea is leading in the LCD industry, but our basic research on LCs is not at the world's research level."
The first author of this study is Dr. Min-Jun Gimand supported by a grant from the National Research Foundation (NRF) and funded by the Korean Government (MSIP). The research result was published on May 30, 2017 in Nature Communications.
Figure 1. The phase transition of the LC topological defect on cooling.
Figure 2. Polarizing optical microscopy images of topological defects depending on the strength of the director field. (a,b,e) Convergent director field arrangements of LC molecules and corresponding schematic images; (c,d,f) Divergent director field arrangements of LC molecules and corresponding schematic images.
2017.06.02 View 10779 -
2017 ICISTS Conference 'Draw the Web: Interactions in Society'
The KAIST undergraduate organization, ICISTS (International Conference for Integration of Science, Technology and Society) will convene its annual conference from July 31 to Aug. 4 at the KAIST Daejeon Campus. This year’s theme is “Draw the Web: Interactions in Society.” More than 300 participants from 60 universities in 20 countries will participate in the international conference hosted and planned by the student organization.
Speakers at the 2017 conference include leaders in technology, business, investment, and entrepreneurship, and many others highlighted by Christoffer O. Hernæs, chief digital officer of Skandiabanken and vice president of strategy and innovation at Sparebank; Vincent C. Müller, professor of the philosophy division of humanities & social sciences at Anatolia College; Nigel Parker, director of developer and platform evangelism at Microsoft APAC; and Jon Gosier, founder and CEO of WoundedMetrics, who was voted as one of the 25 most influential African-Americans in technology by Business Insider in 2013 and 2014.
ICISTS has organized and hosted this event, the largest academic conference hosted and organized by students in Asia, since 2005 as a way to discuss an incredibly challenging issue: how science and technology is being integrated into society. This year’s conference will explore how prominent technological advancements are integrated, and how the interactions between humanity and technology will affect society. This year’s sub-theme is “Settlement, Movement, and Inequality.”
In addition to the main session, ICISTS is preparing discussion sessions in which guest speakers and participants will divide into small groups to discuss their responses to the themes. Various additional events including a culture night and an excursion program will serve as opportunities to network with other participants. For more information on the program and how to register, please visit http://www.icist.org.
2017.05.22 View 9138 -
Prof. Sang-Min Bae Receives 2017 iF Design Award
Prof. Sang-Min Bae and his research team from the Industrial Design Department of KAIST submitted a winning entry to the 2017 iF Design Award named ‘Culture BOXCHOOL’.
The iF Design Award is an internationally renowned design contest that is recognized as one of the top three design awards in the world along with the Red Dot Design Award and the IDEA Design Award. It has been held annually by iF International Forum Design since 1953. A total of 5,575 entries from 59 countries entered the last competition.
Culture BOXCHOOL is a modular container space platform designed for culture sharing in isolated areas. It is delivered as a standard shipping container along with its subsidiary modular parts and it transforms into a gallery, office, or classroom. These modular parts build the interior and exterior by attaching them to the corner castings, which are standard parts on all shipping containers. Two Cultural BOXCHOOL containers can be transformed into three different types of layouts.
The containers can generate their own energy using solar panels that provide sustainable energy to equipment inside. Additionally, hot humid air can flow out through the attic vent, doors, and windows.
“With Culture BOXCHOOL, you can easily and quickly create spaces such as offices and classrooms, or you can easily disassemble and move them to another location.
Thus, it can provide everyone with equal educational opportunities and cultural enjoyment regardless of their geographical location. In addition, because it produces its own energy, it is expected to create a cultural space in a relatively harsh environment such as in developing countries. These social and economic values of Culture BOXCHOOL seem to be what led to us winning the contest. I will continue to strive to create the world’s best designs for needy people.” Professor Bae said.
The ID+IM design laboratory, a research team led by Professor Bae, has been studying philanthropy design since 2005, working on solving various problems throughout society through innovative design. They have received more than 50 awards from the most prestigious design competitions in the world.
2017.05.18 View 9375 -
Crowdsourcing-Based Global Indoor Positioning System
Research team of Professor Dong-Soo Han of the School of Computing Intelligent Service Lab at KAIST developed a system for providing global indoor localization using Wi-Fi signals. The technology uses numerous smartphones to collect fingerprints of location data and label them automatically, significantly reducing the cost of constructing an indoor localization system while maintaining high accuracy.
The method can be used in any building in the world, provided the floor plan is available and there are Wi-Fi fingerprints to collect. To accurately collect and label the location information of the Wi-Fi fingerprints, the research team analyzed indoor space utilization. This led to technology that classified indoor spaces into places used for stationary tasks (resting spaces) and spaces used to reach said places (transient spaces), and utilized separate algorithms to optimally and automatically collect location labelling data.
Years ago, the team implemented a way to automatically label resting space locations from signals collected in various contexts such as homes, shops, and offices via the users’ home or office address information. The latest method allows for the automatic labelling of transient space locations such as hallways, lobbies, and stairs using unsupervised learning, without any additional location information. Testing in KAIST’s N5 building and the 7th floor of N1 building manifested the technology is capable of accuracy up to three or four meters given enough training data. The accuracy level is comparable to technology using manually-labeled location information.
Google, Microsoft, and other multinational corporations collected tens of thousands of floor plans for their indoor localization projects. Indoor radio map construction was also attempted by the firms but proved more difficult. As a result, existing indoor localization services were often plagued by inaccuracies. In Korea, COEX, Lotte World Tower, and other landmarks provide comparatively accurate indoor localization, but most buildings suffer from the lack of radio maps, preventing indoor localization services.
Professor Han said, “This technology allows the easy deployment of highly accurate indoor localization systems in any building in the world. In the near future, most indoor spaces will be able to provide localization services, just like outdoor spaces.” He further added that smartphone-collected Wi-Fi fingerprints have been unutilized and often discarded, but now they should be treated as invaluable resources, which create a new big data field of Wi-Fi fingerprints. This new indoor navigation technology is likely to be valuable to Google, Apple, or other global firms providing indoor positioning services globally. The technology will also be valuable for helping domestic firms provide positioning services.
Professor Han added that “the new global indoor localization system deployment technology will be added to KAILOS, KAIST’s indoor localization system.” KAILOS was released in 2014 as KAIST’s open platform for indoor localization service, allowing anyone in the world to add floor plans to KAILOS, and collect the building’s Wi-Fi fingerprints for a universal indoor localization service. As localization accuracy improves in indoor environments, despite the absence of GPS signals, applications such as location-based SNS, location-based IoT, and location-based O2O are expected to take off, leading to various improvements in convenience and safety. Integrated indoor-outdoor navigation services are also visible on the horizon, fusing vehicular navigation technology with indoor navigation.
Professor Han’s research was published in IEEE Transactions on Mobile Computing (TMC) in November in 2016.
For more, please visit http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=7349230http://ieeexplore.ieee.org/document/7805133/
2017.04.06 View 10388 -
KAIST's Future Strategy Graduate School Holds Its 100th Public Forum
The Graduate School of Future Strategy at KAIST has hosted regularly a public forum on Fridays at the Korea Telecom building in Seoul, to offer an open platform for policy discussions and exchange ideas since its establishment in 2012.
This Friday’s forum on March 17, 2017 will mark the hundredth of its kind.
The forum has served as a weekly meeting at which experts and citizens from various professional backgrounds gather together and share their views and insights on strategies and policies to help Korea advance toward a better future. As a result, the forum has implemented its role as a catalyst for “collected intellectualism.”
To date, over 200 participants have engaged in discussions and put forward suggestions on such issues as future strategies, a smart defense system, mid- and long-term national development, artificial intelligence (AI), the Internet of Things, augmented reality, robotics, and future automotive technology. The forum has also taken the lead in identifying issues that will become important to national progress in the era of the Fourth Industrial Revolution.
Among the notable topics discussed so far, the aftermath of the Al-embedded video game of Go, AlphpaGo’s match against a human player, which took place in March last year in Korea, attracted a great deal of attention from the public.
The Friday’s forum will discuss ways to unify the divisive public views over the recent political issue of the presidential impeachment and explore strategies to promote mutual growth and solidity. The event will be conducted in Korean only, and also be aired live via the Africa Web Television and Facebook for online participation.
Ideas proposed and suggested during discussions are compiled and published annually as a book entitled “The National Future Strategy for the Republic of Korea.”
Professor Kwang Hyung Lee of the Future Strategy Graduate School said, “When we first envisioned this setting for these discussions, no one at our school really thought that we would host the forum 100 times. It has lasted much longer than we could have imagined, and we hope that this will continue to remain relevant to society as a meaningful public venue to think about our nation’s future.”
2017.03.16 View 4342 -
Highly-Efficient Photoelectrochemical CO2 Reduction
Direct CO2 conversion has continuously attracted a great deal of attention as a technology to produce fuels and chemical building blocks from renewable energy resources. Specifically, substances such as carbon feedstocks and fuels can be produced by utilizing sunlight, water, and CO2 as semiconductors and a water interface through photoelectrochemical CO2 reduction.
A KAIST research team demonstrated a novel photoelectrode structure for highly-selective and efficient photoelectrochemical CO2 reduction reactions. The research team led by Professor Jihun Oh of the Graduate School of EEWS (Energy, Environment, Water and Sustainability) presented a Si photoelectrode with a nanoporous Au thin film that is capable of reducing CO2 to CO with 90 percent selectivity in aqueous solution. The research team’s technology will provide a basic framework for designing the semiconductor photoelectrode structure necessary for photoelectrochemical conversion.
In order to achieve steady conversion of CO2, it is necessary to use a high-performance catalyst to lower overpotential. Among the metal catalysts, Au is known to be an electrocatalyst that converts CO2 to CO.
Conventionally, bare Au, as a catalyst, produces a lot of hydrogen gas due to its low CO selectivity. In addition, the high cost of Au remains a challenge in using the catalyst. Professor Oh’s research team addressed the issue by creating a nanoporous Au thin film formed by the electrochemical reduction of an anodized Au thin film.
As a result, the team could demonstrate an efficient, selective photoelectrochemical reduction reaction of CO2 to CO using electrochemically-treated Au thin films on a Si photoelectrode. The electrochemical reduction on anodized Au thin films forms a nanoporous thin layer exhibiting many grain boundaries of nanoparticles on the Au surface. This dramatically improves the selectivity of the reduction reaction with a maximum CO faradaic efficiency of over 90% at low overpotential and durability.
The research team also used an Au thin film of about 200 nanometers, 50,000 times thinner than previously reported nanostructured Au catalysts, resulting in a cost-effective catalyst. When depositing the catalyst on the semiconductor surface in the type of nanoparticles, the substrate of the thin film will be affected in the course of electrochemical reduction.
Thus, the research team designed a new Si photoelectrode with mesh-type co-catalysts that are independently wired at the front and back of the photoelectrode without influencing the photoelectrode, and made it possible for electrochemical reduction.
Due to the superior CO2 reduction reaction activity of the nanoporous Au mesh and high photovoltage from Si, the Si photoelectrode with the nanoporous Au thin film mesh shows conversion of CO2 to CO with 91% Faradaic efficiency at positive potential than CO equilibrium potential.
Professor Oh explained, “This technology will serve as a platform for diverse semiconductors and catalysts. Researchers can further improve the solar-to-CO2 conversion efficiency using this technology.
Dr. Jun Tae Song, the first author continued, “This new approach made it possible to develop a simple but very important type of electrode structure. It is the first time to achieve CO2 conversion at the potential lower than equilibrium potential. We believe that our research will contribute to efficient CO2 conversion.”
This research was published in the inside front cover of Advanced Energy Materials on February 8, 2017. The research was funded and supported by the Korea Carbon Capture & Sequestration R&D Center. Professor Sung-Yoon Chung of the EEWS also participated in this research.
(Figure: Schematic diagram of a Si photoelectrode that patterns with mesh-type nanoporous Au)
2017.03.08 View 10454 -
13 KAIST Faculty Named as Inaugural Members of Y-KAST
The Korean Academy of Science and Technology (KAST) launched the Young Korean Academy of Science and Technology (Y-KAST) and selected 73 scientists as its inaugural members on February 24. Among them, 13 KAIST faculty were recognized as the inaugural members of Y-KAST.
Y-KAIST, made up of distinguished mid-career scientists under the age of 45, will take the leading role in international collaboration as well as innovative agenda-making in science and technology.
The inaugural members include Professor Hyotcherl Ihee of the Department of Chemistry and Dr. Sung-Jin Oh of the Center for Mathematical Challenges at the Korea Institute for Advanced Study (KIAS), affiliated with KAIST. Professor Ihee is gaining wide acclaim in the fields of physics and chemistry, and in 2016, Dr. Oh was the youngest ever awardee of the Presidential Award of Young Scientist.
The other Y-KAIST members are as follows: Professors Haeshin Lee of the Department of Chemistry; Mi Young Kim, Byung-Kwan Cho, and Ji-Joon Song of the Department of Biological Sciences; Song-Yong Kim of the Department of Mechanical Engineering; Sang-il Oum of the Department of Mathematical Sciences; Jung Kyoon Choi of the Department of Bio and Brain Engineering; Seokwoo Jeon, Sang Ouk Kim, and Il-Doo Kim of the Department of Materials Science and Engineering; Jang Wook Choi of the Graduate School of EEWS (Energy, Environment, Water and Sustainability); and Jeong Ho Lee of the Graduate School of Medical Science and Engineering.
The leading countries of the Academy of Science, which include Germany, Sweden, Belgium, Canada, and Japan, have established the Young Academy of Science since 2010 in order to encourage the research activities of their young scientists and to establish a global platform for collaborative research projects through their active networking at home and abroad.
President Myung-Chul Lee of KAST said, “We will spare no effort to connect these outstanding mid-career researchers for their future collaboration. Their networking will make significant impacts toward their own research activities as well as the global stature of Korea’s science and technology R&D.
(Photo caption: Members of Y-KAST pose at the inaugural ceremony of Y-KAST on February 24.)
2017.03.02 View 19252 -
The 2016 Research Highlights
KAIST has selected the ten most outstanding projects of 2016 conducted by its faculty and researchers. This selection embodies the KAIST research portfolios that translate their discoveries into meaningful and measurable impact toward a better world. All of them demonstrate exceptional creativity, which open new research paths for each field in its novelty, innovation, and impact.
The following list has been reviewed by a committee of faculty peers headed by Associate Vice President for Research. Following are the 2016 KAIST research highlights:
□ Commercialization of 3D Holographic Microscopy
By YongKeun Park of the Department of Physics
Professor YongKeun Park and his colleagues develop a powerful technique to measure 3D images of live cells without labeling agents. This technique, called 3D holographic microscopy or holotomography, will open a new avenue for the study of cell biology and its applications in medical diagnosis. This research also led to the founding of a start-up company Tomocube Inc. and the successful commercialization of the technique.
Professor Park and his research team developed a solution based on digital holography technology used to visualize 3D refractive index tomograms of live cells without staining. This allowed the real-time observation of biological cells in 2D, 3D, and 4D without the use of labeling agents. Conventional techniques for 3D cell imaging requires the use of labeling agents such as fluorescence dyes and proteins, which prevent from investigating the physiology of intact untreated cells. In particular, label-free imaging capability becomes more important in several emerging fields such as stem cell research and immunotherapy.
The team employs the concept of 3D digital holography to achieve the optical measurements of 3D refractive index tomograms of live cells and tissues. Also, a digital micromirror device (DMD), which has been used for DLPTM projectors, was utilized to steer a laser beam for 3D measurements.
Tomocube, founded from seed money funded by the EndRun Project of the Institute for Startup KAIST, succeeded in the commercialization of the 3D holographic microscopy and established an international distribution network in more than ten countries. It now has started exporting the product to several countries. The microscopes are being used in several leading research institutes including MIT, German Cancer Center, Pittsburg Medical Center, and Seoul National University Hospital Selected as one of the top ten mechanical technologies of 2016 by the Korean Society of Mechanical Engineers, the team raised four billion KRW investment from industry leaders including Soft Bank Venture Korea, Hanmi Pharmaceutical, and InterVest investment.
(Figure: Images of cells measured by 3D microscopy)
□ Designer Proteins with Chemical Modifications
By Hee-Sung Park and Hee Yoon Lee of the Department of Chemistry
Professor Hee-Sung Park developed a new strategy for installing authentic post-translational modifications (PTM) into recombinant proteins. Most essential biological processes are controlled by PTM, which plays a critical role in metabolic changes. However, abnormal protein modification aroused by environmental or genetic factors induce diverse diseases such as neurodegenerative diseases, cancer, and many other chronic diseases.
Professor Park has conceived a novel chemical biology route to achieve authentic and selective chemical modifications in proteins.He first used the established O-phosphoserine (Sep) orthogonal translational system to create a Sep-containing protein. The Sep residue is then dephosphorylated to dehydroalanine (Dha). Finally, Zn-Cu is conjugated to Dha of alkyl iodides, which enables it to form chemo-selective carbon-carbon bonds.
This approach offers a powerful tool to engineer designer proteins with diverse chemical modifications, providing a novel platform for investigating numerous diseases and drug development including for cancer and Alzheimer's. Furthermore, this research will allow mass production of abnormally modified proteins that could induce diseases, opening up new prospects in disease treatment research. It will help to enable investigation and discovery of new drug inhibitors that directly target abnormally modified proteins.
(Figure: Application of Customized Protein Modification Technology)
□ Lanthanum-Catalyzed Synthesis of Microporous 3D Graphene-Like Carbons in a Zeolite Template
By Ryong Ryoo, of the Department of Chemistry
Professor Ryong Ryoo’s team presented a scaled-up carbon synthesis viable for practical applications such as Li-ion batteries and catalyst supports.
Zeolite-templated carbon has an extremely large surface area and a regular microporous structure. As a result, it was expected to show excellent performance in various applications, such as for electrode materials or catalyst supports. However, until recently difficulties in synthesis have hindered research on application and properties of zeolited-templated carbon compared to other porous carbon materials.
Professor Ryoo’s team demonstrated that lanthanum ions embedded in zeolite pores lowered the temperature for carbonization of ethylene or acetylene. In this contribution, a graphene-like carbon structure was selectively formed inside zeolite template without the non-selective carbon deposition. Single crystal X-ray diffraction data revealed that carbon formed along the micropore surface. After removal of zeolite template, the carbon framework showed high electrical conductivity.
His synthesis method not only allowed selectivity in ethylene carbonization inside zeolite pore but permitted the diffusion of carbon material even when a large amount of zeolites was synthesized at once, allowing mass production of carbon. Thus, this method is expected to accelerate research on the application and properties of zeolite-templated carbon.
(Figure: Electron density distribution of zeolite that underwent selective pore carbonization. The structure of carbon determined by electron density distributions of carbon atoms, shown in yellow and red, within the framework of zeolite, shown in blue, can be observed.)
□ Complete Prevention of Blood Loss by Self-Sealing Hemostatic Needles
By Haeshin Lee of the Department of Chemistry
Professor Haeshin Lee’s team invented a hemostatic hypodermic needle, which prevented bleeding of punctured tissue during and after injections.
Bleeding unavoidably accompanies injections when a conventional needle penetrates tissue. Though the scale of bleeding from controlled injections does not cause harm to healthy individuals, uncontrolled bleeding may bring serious complications for those who suffer from hemophilia, coagulopathy, or who have been exposed to infectious diseases.
Professor Lee’s hemostatic hypodermic needle is coated with partially cross-linked catechol-functionalized chitosan that undergoes a solid-to-gel phase transition in situ to seal-seal punctured tissues. The team reported a complete prevention of blood loss following intravenous and intramuscular injections in animal models. They observed a 100% survival rate in hemophiliac mice following a syringe injection into a jugular vein.
The self-sealing hemostatic needles may help to prevent complications associated with bleeding in clinical settings such as for diabetic patients who experience delayed hemostasis and in the procedure of biopsy thereby preventing profuse bleeding.
□ An Immunological Mechanism for the Contribution of Commensal Microbiota Against Herpes Simplex Virus Infection in Genital Mucosa
By Heung Kyu Lee of the Graduate School of Medical Science and Engineering
Professor Heung Kyu Lee identified an immunological mechanism of commensal microbiota against herpes virus infections. The protective mechanisms of commensal bacteria against viral infections was limited to how immune inductive signals are provided by commensal bacteria for enhancing innate and adaptive immunity. Until Professor Lee’s research discovery, whether, or how, commensal bacteria might influence the effector arm of immune responses such as effector T cells to eliminate infected virus remained unknown.
Professor Lee’s team demonstrated that dysbiosis within the vaginal microbiota resulted in severe impairment of antiviral protection against HSV-2 infection. IL-33 released into the vaginal tract after antibiotic treatment blocked the ability of effector T cells to migrate into vaginal tissues and secrete the antiviral cytokine, IFN-γ. Thus, the findings suggested a previously unstudied role of commensal bacteria in the effector phase of the antiviral immune response against genital herpes. These findings provided insight into the mechanisms by which the secretion of proteases from opportunistic pathogens in susceptibility to various sexually transmitted pathogens might induce type 2 immunity within the female genital tract.
Promoting awareness of overuse of antibiotics, the research is expected to contribute to the development of viral vaccines with enhanced defense capacity by regulating commensal bacteria to promote health.
□ Development of a Pulse-Echo Laser Ultrasonic Propagation Imaging System
By Jung-Ryul Lee of the Department of Aerospace Engineering
Professor Jung-Ryul Lee’s team for the first time developed a mobile laser ultrasonic propagation imaging system that is capable of 2500-point inspection per second and visualization of pulse-echo ultrasonic wave through the thickness of a solid medium. This novel ultrasonic propagation visualization system has been successfully prototyped for the application of in-situ and in-process nondestructive evaluation of aerospace structures.
The real world proof-of-concept was achieved by testing the new system in the inspection of a space launcher fuselage (KSLV-II), control surfaces of military transport (CN-235), and the brake disk of F-16, guided weapon fuselage. In addition, the system has passed F-16 standard specimen test done by Korea Air Force and got a US patent. The prototype which was developed over a period of two years has been successfully delivered to Korea Air Force last December.
Furthermore, Boeing has expressed interest in prototype development project and KAIST OESL has been selected as the Boeing-KAIST technical contact lab and received a two-year grant from Boeing. The second prototype is under construction for Boeing and the third prototype will be delivered to an optional research institute and used as a standard inspection instrument.
□ Birefractive Stereo Imaging for Single-Shot Depth Acquisition
By Min H. Kim of the School of Computing
Professor Min H. Kim’s team proposed a novel 3D imaging method that allows the capture of not only color pictures but also corresponding depth images while traditional cameras capture just color pictures.
Depending on the polarization state of light, the incident light on a birefringent material such as calcite can be refracted into two different angles. This physical phenomenon is called double refraction. Whereas traditional stereo imaging requires at least two stereo cameras, 3D imaging method can capture depth from a single picture of double refraction. This proposed 3D imaging technique can be applied to many graphics and computer vision applications such as AR/VR applications that require color and depth information simultaneously.
This technology, which could measure depth images, is currently needed for various industrial applications. The suggested method in this research to measure depth information from one photo using double refraction media accurately can be used in areas where system size and cost are important, such as mobile cameras, VR/ARs, driverless cars, and 3D microscopes.
(Figure: Measuring high-resolution depth of single image via bi-refringent medium)
□Development of Environment Friendly Geotechnical Construction Material Using Biopolymer
By Gye-Chun Cho of the Department of Civil and Environmental Engineering
Professor Gye-Chun Cho has succeeded in making a 100% bio-based KABS (KAIST Bio-Soil) binder using biopolymer, an eco-friendly geotechnical construction material. A biopolymer is an organic polymer produced in the course of microbial activities and thus is an eco-friendly material manufactured without generating carbon dioxide. Biopolymers have been used in food, agriculture, cosmetics, and medicine as hardener and gelling agents, but have never been applied in construction. His team verified the microscopic interaction, feasibility, and strengthening mechanism of microbial biopolymers for soils for the first time in the world, suggesting that biopolymers be an eco-friendly soil binder.
In addition to soil binders, biopolymers can also be applied to various fields of ground construction (e.g., ground improvement, grouting, erosion control, vegetation, anti-desertification, etc.). The team expects more biopolymer applications in construction since increasing demands for replacing cement-based or chemical ground materials have surged.
With KABS binder, the team has performed several field tests along with industrial technology transfer underway. In collaboration with the Korea Expressway Corporation and LH Corporation, Professor Cho’s team is working on additional commercial applications.
(Figure: Strength enhancement effect of soil grain processed by biopolymer )
□ Protein Delivery Via Engineered Exosomes
By Chulhee Choi of the Department of Bio and Brain Engineering
Professor Chulhee Choi’s team unveiled a new tool for intracellular delivery of target proteins, named “exosomes for protein loading via optically reversible protein-protein interactions” or “EXPLORs”.
Nanoparticle-mediated delivery of functional macromolecules is a promising method for treating a variety of human diseases. Among nanoparticles, cell-derived exosomes have recently gained attention as a new therapeutic strategy for the in vivo delivery of nucleotides and chemical drugs.
By integrating a reversible protein-protein interaction module controlled by blue light with the endogenous process of exosome biogenesis, the team successfully loaded cargo proteins into newly generated exosomes. Treatment with protein-loaded EXPLORs is shown to significantly increase intracellular levels of cargo proteins and their function in recipient cells in vitro and in vivo.
These results clearly indicate the potential of EXPLORs as a mechanism for the efficient intracellular transfer of protein-based therapeutics into recipient cells and tissues. This technology has been transferred to KAIST bio-venture Cellex Life Science, Incorporated for commercialization.
□ Hot Electron Detection under Catalytic Reactions
By Jeong Young Park of the Graduate School of EEWS
Professor Jeong Young Park’s team developed a novel catalytic nanodiode consisting of a thin metal catalyst deposited onto a semiconductor support. The team succeeded in observing in real-time hot electrons created in the course of catalytic reaction occurring at atmospheric pressure or at liquid-solid interfaces.
Use of a noble catalytic nanodiode is a new measurement system that detects hot electrons produced on catalyst surface through atmospheric pressure and liquid chemical reaction in real time that allows direct identification of the catalytic activity of catalytic reactions. In particular, the system allows macro-observation of hot-electron movements that change with the type of nano-catalyst without high-priced equipment in atmospheric pressure and liquidation, and thus is not limited to experimental conditions such as in ultrahigh vacuums.
Therefore, it could be applied in the future to analyze complex chemical reaction mechanisms of catalysts used in high temperature and various pressure conditions, and to develop high efficiency next-generation catalyst materials. This finding may lead not only to the fundamental understanding in the mechanism of the catalytic reactions but also to the development of next-generation catalysts with enhanced catalytic performance.
(Figure: Schematic diagrams of nano-catalyst hot electron element and graphene hot electron detector)
2017.02.20 View 13986 -
Dr.M Drives Smart Healthcare Industry in Partnership with Hancom
President Sung-Mo Kang signed an agreement on January 25 with Hancom Group Chairman Sang Chul Kim to establish a smart healthcare complex in Gapyeong, Kyonggido. With the Gapyeong complex launch, KAIST will come to commercialize Dr. M system along with other Dr.M consortium members as a new growth engine to drive the smart health industry.
Dr. M is a smart healthcare platform developed by the Health Science Research Institute at KAIST in 2014. Dr. M is capable of analyzing and predicting diseases, as well as prescribing, by incorporating ICT and medical technologies. Dr. M applies diverse technologies such as healthcare sensors, wearable devices, low-power communications technology, and cloud and big data collection platforms.
Hancom Group, a leading computer software company in Korea, has participated in the project since 2015 for advancing the smart healthcare market by developing mobile healthcare software program. Hancom joined the Dr.M consortium launched last November.
(President Kang (left) poses with Hancom Chairman Kim after signing.)
2017.02.03 View 7438 -
KAIST Joins IoF 2020 with 'Oliot'
KAIST will take part in the Internet of Food & Farm 2020 (IoF 2020) project with its international standard IoT open source platform ‘Oliot’ (Open Language for the Internet of Things, http://oliot.org), developed by a research team under Professor Daeyoung Kim from the School of Computing. Dr. Kim is also the director at the Auto-ID Labs at KAIST (http://autoidlabs.org).
IoF 2020 is a project to provide solutions and facilitate the large-scale uptake of IoT by addressing the organizational and technological challenges the European farming and food sectors face today. The project will develop innovative IoT solutions by fostering co-creation in interactive improvement cycles focusing on user acceptability and business models to boost technology and market-readiness levels.
Along with 71 partners from 16 countries, Professor Kim’s ‘Oliot’ will play a part in creating an ecosystem for providing safe and healthy agrifood, incorporating ICT(information and communications technologies) into the areas of smart farms and the agrifood service sector over the next four years. The project received €30 million in funding from Horizon 2020, the largest research and innovation program in the EU. KAIST is the only Korean institution to participate in this project.
For the project, Professor Kim’s team will initially establish smart farm and food service testbeds for the domestic agrifood industry with ‘Oliot’ prior to connecting to the European one. Professor Kim said he will leverage Artificial Intelligence (AI) and deep learning in order to analyze the data collected from the ecosystems in the EU. He aims to open an integrated IoT platform system incorporated with AI technologies to serve governments, institutions, corporations, and farmers.
It is expected that technologies developed for IoF 2020 will also benefit the domestic agrifood market and its supply chain infrastructure. Oliot will also be expected to further advance domestic smart industries including health care and connected vehicles.
George Beers, project manager at Wageningen University & Research and the IoF 2020 project coordinator said, “IoF 2020 has the potential to transform the paradigm of the supply chain of agrifood from the farm to consumers’ dining tables. We believe this project will contribute to enhance European competitiveness and excellence in the food commerce industry.”
Professor Kim said, “Technological applications of international standard IoT have already started in the domestic agrifood industry in collaboration with KAIST. We are working now with Asian and South American countries, as well as European nations, for the integration of a global agrifood business ecosystem.”
Auto-ID Labs are a global research consortium of seven academic institutions that research and develop new technologies for advancing global commerce, partnering with GS1 (Global Standard 1), a non-profit organization that established standards for global commerce such as introducing barcodes to the retail industry. The Auto-ID Labs include MIT, University of Cambridge, Keio University, Fudan University, and ETH Zurich/University of St. Gallen as well as KAIST.
2017.01.18 View 8082 -
KAIST to Participate in the 2017 Davos Forum
(President Sung-Mo Kang and Distinguished Professor Sang Yup Lee)
KAIST representatives will join high profile, multi-stakeholder dialogues with global leaders across the world to discuss higher education, science, and technological innovation.
KAIST President Sung-Mo Kang and Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department will participate in the World Economic Forum’s (WEF) Annual Meeting on January 17-20, 2017, in Davos-Klosters, Switzerland.
To be held under the theme “Responsive and Responsible Leadership,” the Annual Meeting will offer global leaders from government, business, academia, and civil society a highly interactive platform to address some of the most pressing issues facing the world today, from climate change, economic inequality, to the Fourth Industrial Revolution and its impact on future employment.
On January 18, President Kang will participate in the Global University Leaders Forum, a community of top 26 universities invited from around the world, and will discuss the relevance of higher education in the context of the Fourth Industrial Revolution. He will also share KAIST’s experiences in developing innovative initiatives to bring future-oriented and creative values into its educational and research programs.
On January 19, at the Global Future Council on Production, President Kang will speak about new technologies taking place in traditional production and distribution systems as introduced by the emergence of rapidly evolving technological advancements, and present KAIST’s endeavors to transform those changes into opportunities.
With an eminent group of scientists, including the Director of the US National Science Foundation France A. Córdova and the Editor-in-Chief Philip Campbell of Nature at the Global Science Outlook session, on January 20, President Kang will discuss key challenges for the global science agenda in the year ahead and examine the role of science in formulating public discussions and polices that will have great impact on society and the lives of people.
Currently, Professor Lee is the founding Co-Chair of the WEF’s Global Future Council, an interdisciplinary knowledge network dedicated to promoting innovative thinking on the future. On January 20, he will share his insights at an independent session entitled “World Changing Technology: Biotech and Neurotech,” briefing the audience on the current state of research, development, and commercialization in these fields, as well as explaining how they will contribute to coping with the Fourth Industrial Revolution.
Professor Lee said, “In recent years, we have seen the world become ever more complex, interconnected, and realigned as it is deeply affected by this unprecedented technological innovations, collectively driving the Fourth Industrial Revolution. One pillar of such innovation will take place in biotechnology and neuroscience, which will help us design solutions to many of global problems such as environment, pandemic diseases, aging, healthcare, and previously intractable illnesses.”
President Kang added, “This year’s Davos meeting will focus on the need to foster leadership at the national, regional, and global level to respond collectively with credible actions to issues of major concern for the sustainable and equitable growth, social inclusion, and human development. KAIST has always been a crucial player in these collaborative efforts, and I am happy to share our insights at the upcoming event.”
2017.01.17 View 9796