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Professor Sang-Yup Lee publishes a requested paper in Nature Biotechnology
Professor Sang-Yup Lee publishes a requested paper in Nature Biotechnology
“The era of commercialized bioplastic is coming”
Disclose an opinion as specialist at a requested paper in Nature Biotechnology, October 2006
A team led by Barbel Friedrich, Professor of Humboldt-Universitat zu Berlin, and Alexander Steinbuchel, Professor of West falische Wilhelms-Universitat Munster, found out the entire genome sequence of the typical bioplastic-producing microorganism ‘Ralstonia eutropha’ and published a paper on it in Nature Biotechnology, October 2006. As the entire genome sequence of the typical bioplactic-producing microorganism has been discovered, it is expected that the efficient production of bioplastic will be available through strain improvement at a more systematic level.
Regarding this paper, Nature Biotechnology requested world-renowned scholar Sang-Yup Lee, LG Chemical Chair-Professor of KAIST Chemical and Biomolecular Engineering Department, an expert analysis on the future of bioplastic production as a result of the deciphering of the genome sequence, and Professor Lee revealed his opinion at ‘News and Views’ in Nature Biotechnology, October 2006, issued on October 10. In the analysis, he insisted, “The deciphering of the genomes of Ralstonia means to pave the way for the improvement of strains at a system level by combining simulation through various omics and imaginary cells and engineering at a genome level. It will be possible to produce plastic with desired properties by altering the components of plastic as desired and produce bioplastic, more efficient and economical than have been reported so far, through the optimization of metabolic flow.”
Professor Lee is a world-renowned scholar in the bioplastic field, who has presented about 70 SCI papers in the field. He created a word ‘Plastic Bacteria’ at Trends in Biotechnology in 1996 and published an expert paper regarding E.Coli Plastic at Nature Biotechnology in 1997. He is now performing a research concerning the improvement of bioplastic-producing strains as an example of a research employing a systematic method for the system biological research and development project of the Ministry of Science and Technology.
The followings are the contents of Professor Lee’s paper concerning microorganism plastic published at ‘News and Views’ in Nature Biotechnology, October 2006.
- Polyhydroxyalkanoate (PHA) is a high molecule that numerous microorganisms accumulate in their own cells as energy storage substance when they are rich in carbonic resources, but poor in the other growth factors. The PHA high molecule is polyester, in which the unit substances (unit chemicals) are ester-bonded, and has been studied worldwide about twenty years before. However, PHA’s worse properties than petrochemical plastic and extremely high production cost have prevented its commercialization. The production cost of PHA was 15 dollars per kg in 1980’s, twenty times higher than the price of polypropylene. Sang-Yup Lee, LG Chemical Chair-Professor of KAIST Chemical & Biomolecular Department’s BK21 Project Group, has performed a research concerning the efficient production of microorganism plastic through the combination of metabolic engineering and fermentation process under the support of the Ministry of Science and Technology, and developed a process that lowers the production cost of PHA to 2-3 dollars per kg. He also has developed PHA-producing bacteria, efficient enough to fill plastic tightly, and named it ‘Plastic Bacteria’.
- The unprecedented rise of oil price for the past two years activated the researches on Bio-based energies and chemical production globally. PHA is also regaining attentions although the researches on it have been withered so far due to its poor economical efficiency and properties. The result of the genome deciphering of the typical plastic-producing microorganism ‘Ralstonia eutropha’ published by a German research team in Nature Biotechnology, October 2006 suggests huge meanings. That is, it will provide a blueprint over the metabolic activities of the bacteria and thus enables more systematic strain improvement.
- Eyeing on these facts, Nature Biotechnology requested Professor Sang-Yup Lee an expert analysis, and Professor Lee analyzed that there would be a dramatic development of microorganism plastic production through the application of the system biological engineering method, which is now being performed actively by Professor Lee at KAIST. In the analysis, Professor Lee revealed, “As the genome sequence has been found out, it becomes possible to establish metabolic network at a genome level, and since simulation becomes available, numberless trial and errors and experiments can be replaced with imaginary experiments rapidly. In addition, It makes the more efficient development of strains possible by fusion-analyzing the omics result such as various transcripts, proteins, metabolites, etc.” He also expected that it would be possible to produce tailor-made PHA having desired properties through metabolic engineering as well as the efficient production of plastic. Besides, he prospected that his research on the production of optically pure hydroxyl carboxyl acid, Professor Lee’s international patent right, would gain driving forces and technical development would be made rapidly at biological hydrogen production, production, dissolution and application of aromatic compounds, etc. by featuring this strain.
- Recently, Metabolic and ADM, U.S. companies, jointly started to produce PHA at a commercialization level, and Brazil having rich natural resources is commercializing PHA, following Bio-ethanol. In addition, Japan and Germany having a bunch of research performance in this field, and Australia having rich biomass are also performing consistent researches on PHA’s commercialization. Professor Lee prospected, “With the finding out of the genome sequence of the typical bioplastic-producing microorganism, competition for commercialization will be fiercer among nations through the development of efficient production systems.”
- Professor Lee prospected that as the efficient production of PHA becomes possible, the production of plastic from various renewable ingredients (cellurose, starch, suger, etc.) through microorganism fermentation would be made practically and the white biotechnologies of existing chemicals would gain more power. He also said, “Korea also will have to try to secure the production technologies and industry of Bio-based chemicals through strategic cooperation with resource powerfuls, etc. on the basis of the technical dominancy in some system metabolic engineering fields.”
- ‘News and Views’ in Nature Biotechnology is a section that publishes analyses of world-renowned specialists in the corresponding fields over the contents of some papers having great influences among papers published in the issue. KAIST Professor Sang-Yup Lee has published his second expert analysis of ‘Deciphering bioplastic production’ in the volume of October 2006, following the first paper ‘Going into the era of E.Coli plastic’.
2006.10.23 View 16567 -
H.Y.Choi won BSPA
H.Y.Choi won BSPA
Hyun-Young Choi, Doctor’s course at the Lightwave Systems Research Laboratory (LSRL) of Department of Electrical Engineering of KAIST (Professor in charge Yoonchul Jung), won the Best Student Paper Awards (BSPA) in the Asia-Pacific Optical Communications 2006.
BSPA is awarded to the most prospective paper in the field of Optical Transmission, Switching, and Subsystems. Choi suggested an OSNR monitoring technique among performance monitoring techniques for the efficient maintenance and management of optical network in her paper. Her technique is based on a polarization-nulling method using the polarization features of optical signals. It employs polarization mode dispersion compensator and acousto optic tunable filter (AOTF) to prevent monitoring errors arising from polarization mode dispersion (PMD) and non-linear double refraction, which considerably improves the monitoring technique and makes it possible to demonstrate a technique proposed at ultra long haul network.
2006.10.16 View 14727
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Sona Kwak wins first prize in international robot design contest
Sona Kwak wins first prize in international robot design contest
Sona Kwak (Doctor’s course, Department of Industrial Design) won the first prize in an international robot design contest.
Kwak exhibited an emotional robot of ‘Hamie’ at ‘Robot Design Contest for Students’ in Ro-Man 2006/ The 15th IEEE International Symposium on Robot and Human Interactive Communication, which was held at University of Hertfordshire, United Kingdom for three days from September 6 (Wed) and obtained the glory of the first prize.
‘Hamie’, the work of the first prize, has been devised in terms of emotional communication among human beings. The design concept of ‘Hamie’ is a portable emotional robot that can convey even ‘intimacy’ using senses of seeing, hearing, and touching beyond a simple communication function. The design of ‘Hamie’ was estimated to best coincide with the topic of the contest in consideration of its function that allows emotional mutual action between human beings as well as mutual action between human and robot, or robot and robot. ‘Hamie’ is not an actual embodiment but proposed as ‘a concept and design of a robot’.
‘Ro-man’ is a world-famous academic conference in the research field of mutual action between robot and human being, and ‘Robot Design Contest for Students’ is a contest to scout for creative and artistic ideas on the design and structure of future robots and exhibits works from all over world.
Kwak is now seeking to develop the contents and designs of various next-generation service robots such as ▲ ottoro ? cleaning robot ▲ robot for blind ▲ robot for the old ▲ robot for education assistance ▲ robot for office affairs ▲ ubiquitos robot in her lab (PES Design Lab) led by Professor Myungseok Kim.
“I’ve considered and been disappointed about the role of designers in robot engineering while I’ve been designing robots. I am very proud that my robot design has been recognized in an academic conference of world-famous robot engineers and gained confidence,” Kwak said.
2006.09.27 View 16656
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Ju-pyeong Lee won the Best Paper Award from IEEE RTAS
Ju-pyeong Lee, doctoral student of the Dept. of Electrical Engineering of KAIST, received the Best Paper Award from the 11th Institute of Electrical and Electronics Engineers Real-Time and Embedded Technology and Applications Symposium (IEEE RTAS) sponsored by IEEE TC on Real Time System and supported from the U.S. National Science Foundation.
He is in the Computer Engineering laboratory, and won the honor by his research of technique of Delayed Locking Technique for Improving Real-Time Performance of Embedded Linux by Prediction of Timer Interrupt. His paper was selected to be the best because of its practicality. His research purposed the technique that can dramatically improve real time problem, which was indicated to be the big problem of Linux. Moreover, he presented the way to easily materialize this technique in the practical system.
Best Paper Award is the prize awarded by IEEE Computer Society in the recognition of outstanding achievement in the field of real time system and embedded technology.
IEEE RTAS is a symposium held annually by IEEE. In this year, the 11th symposium was held from March 7 to March 10, for four days, in San Francisco, United States. The purpose of this year symposium was to seek papers describing significant contributions both to state of the art and state of the practice in the broad field of embedded and open real-time computing, control, and communication. Therefore, it especially focused on online real-time and embedded applications ranging from industrial embedded applications such as aeronautics and automotive systems to open multimedia, telecommunication and mobile computing systems.
Approximately 200 related erudite from almost 20 countries including United States, England, France, Germany, Italy, and Sweden participated in this symposium. Total number of papers submitted to IEEE RTAS was 158, while only 53 of them were selected.
by Hye-jung Won / Staff ReporterApril, 2005 / The KAIST Herald
2005.04.12 View 17876
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Personal data found on many used hard drives
JoongAng Daily / 2004.03.09
(photo : Professor Song-chun MoonKAIST Graduate School of Management)
Many secondhand computer hard drives that are being sold through the Internet formerly belonged to businesses and are therefore full of business records containing personal information, the Korea Advanced Institute of Science and Technology (KAIST), a leading local science and technology school, said yesterday.
To determine whether personal information had been properly deleted, the business database research team at KAIST"s business school conducted an experiment in which it randomly bought 41 hard drives through Internet auction sites beginning in April 2003 and analyzed their contents.
It said 26 hard drives out of the total, or 65 percent, had not even been reformatted to remove data. On those drives were business records containing the names, birth dates, home and company addresses, telephone numbers and health examination records of 1,349 people. Also, the team found 568 resident identification numbers on the drives.
"Secondhand hard disks are an open storehouse of personal information [from business records]," said the team"s head, Moon Young-chul. "We found such personal data for an average of 60 people per used disk."
Mr. Moon said that reformatting hard drives alone will not delete all information recorded on them. He said special software designed to completely delete data should be used or such disks should be destroyed.
by Ko Ran / 2004.03.09
2004.04.22 View 14040
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Personal data found on many used hard drives
JoongAng Daily2004.3.9
Many secondhand computer hard drives that are being sold through the Internet formerly belonged to businesses and are therefore full of business records containing personal information, the Korea Advanced Institute of Science and Technology (KAIST), a leading local science and technology school, said yesterday.
To determine whether personal information had been properly deleted, the business database research team at KAIST"s business school conducted an experiment in which it randomly bought 41 hard drives through Internet auction sites beginning in April 2003 and analyzed their contents.
It said 26 hard drives out of the total, or 65 percent, had not even been reformatted to remove data. On those drives were business records containing the names, birth dates, home and company addresses, telephone numbers and health examination records of 1,349 people. Also, the team found 568 resident identification numbers on the drives.
"Secondhand hard disks are an open storehouse of personal information [from business records]," said the team"s head, Moon Young-chul. "We found such personal data for an average of 60 people per used disk."
Mr. Moon said that reformatting hard drives alone will not delete all information recorded on them. He said special software designed to completely delete data should be used or such disks should be destroyed.
2004.03.15 View 13324