RNA
-
KAIST Registers an Internationally Recognized Standard Patent
A video compression technology, jointly developed by Professor Mun-Chul Kim of the Department of Electrical Engineering at KAIST, the Electronics and Telecommunications Research Institute (ETRI), and the Korean Broadcasting System (KBS), is registered internationally as the standard patent in the next-generation High Efficiency Video Coding (HEVC).
HEVC (H.265) is an international technology standard that compresses large image data for Ultra High Definition (UHD) televisions and smartphones. It has the twice the compression efficiency as that of H.264/AVC which is most commonly used for processing full HD sources. This means that it is able to compress a video file to half the size while maintaining the same image quality.
Although the related market is at a nascent stage, HEVC technology has already been applied to the latest version of televisions and smartphones. Experts predict that the market will grow to USD 200 billion by 2016, and KAIST is expected to receive a royalty payment of USD 9.3 million from this patent.
The International Organization for Standardization (ISO/IEC) established the HEVC standard in January 2013. Also, an international patent pool licensing corporation, MPEG LA announced the HEVC standard patent pool on September 29, 2014.
Professor Joongmyeon Bae, Dean of the Office of University-Industry Cooperation (OUIC) of KAIST, said, “This is an unprecedented case for Korea whereby a core technology developed by a university became an international standard, which has a vast impact on the market.”
President of KAIST, Steve Kang commented, “With its advanced technology, KAIST joined the HEVC standard patent pool as one of the 23 founding members along with Apple, Siemens, and NEC. This is a remarkable achievement.”
Picture 1: Improvements in video compression technology
Picture 2: Comparison of different screen resolutions
2014.10.09 View 13119 -
KAIST Ranks 26th in Engineering & Technology and 52nd overall in the Times Higher Education World University Rankings 2014-2015
The 2014-2015 Times Higher Education (THE) World University Rankings were released on October 1, 2014. KAIST took 52nd place in the overall rankings and 26th in the field of engineering and technology.
THE used 13 performance indicators to evaluate universities, grouping them into five areas of teaching, research, citations, industry income, and international outlook.
In recent years, KAIST has seen steady improvements in areas of research, citations, and international outlook. In addition to KAIST, two Korean universities, Seoul National University (50th) and Pohang University of Science and Technology (66th), were included within the top 100 universities.
For details, please visit:
http://www.timeshighereducation.co.uk/world-university-rankings/2014-15/world-ranking.
2014.10.03 View 8840 -
PIBOT, a small humanoid robot flies an aircraft
The 2014 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2014) took place in Chicago, Illinois, on September 14-18, 2014.
Professor David Hyunchul Shim and his students from the Department of Aerospace Engineering, KAIST, presented a research paper entitled “A Robot-machine Interface for Full-functionality Automation Using a Humanoid” at the conference.
The robot called “PIBOT,” a pint-sized, tiny humanoid robot, uses a mixture of flight data and visuals to fly an airplane, capable of identifying and operating all of the buttons and switches in the cockpit of a normal light aircraft designed for humans.
For now, the robot is only flying a simulator, but Professor Shim expects that “PIBOT will help us have a fully automated flight experience, eventually replacing human pilots.”
The IEEE Spectrum magazine published an article on PIBOT posted online September 18, 2014. Please follow the link below for the article:
IEEE Spectrum, September 18, 2014
Tiny Humanoid Robot Learning to Fly Real Airplanes
http://spectrum.ieee.org/automaton/robotics/humanoids/tiny-humanoid-robot-learning-to-fly-real-airplanes
2014.09.23 View 13972 -
QS World University Rankings 2014: KAIST ranked 17th in Engineering and Technology
The QS World University Rankings 2014 were released on October 16, 2014. KAIST ranked 51st among the top 100 global universities which included Massachusetts Institute of Technology (MIT), University of Cambridge, Imperial College London, Harvard University, and University of Oxford. This year’s QS ranking is the highest record ever achieved by KAIST, a great leap from last year’s 60th.
KAIST’s forte in engineering and technology remains high, ranking 17th out of hundreds of universities around the world. Since 2004, KAIST has kept the number one place in this subject within Korea.
Since first being compiled in 2004, the QS rankings have expanded to feature more than 800 universities around the world, and the top 400 universities are given individual ranking positions. The rankings are compiled based on six indicators: academic reputation, employer reputation, faculty/student ratio, citations per faculty, international student ratio, and international staff ratio.
KAIST has earned high scores in three indicators: citations per faculty, academic reputation, and employer reputation.
President Steve Kang of KAIST said, “With concerted efforts made by all members of the KAIST community, faculty and students in particular, we have received a good result in the global rankings. Without dwelling on this result, we will continue to strive toward making KAIST one of the most sought-after universities in the world, academically praised and technologically innovative.”
2014.09.16 View 8901 -
2014 NEREC Conference on Nuclear Nonproliferation: July 31-August 1, 2014, Seoul
The Nonproliferation Education and Research Center (NEREC) at KAIST hosted an international conference on nuclear nonproliferation on July 31-August 1, 2014 in Seoul. The Ministry of Science, ICT and Future Planning, the Korean Nuclear Safety and Security Commission, and the Korea Nuclear Policy Society (KNPS) sponsored the event.
Over one hundred experts and "thought leaders" in nuclear security and nonproliferation attended the conference and discussed issues related to the nonproliferation of nuclear weapons, the role of scientific community in mitigating nuclear threat and promoting the peaceful use of nuclear power, and nuclear disarmament policy.
Keynote speakers were: Steven E. Miller, Director of International Security Program at Belfer Center for Science and International Affairs, Harvard University; Scott D. Sagan, Senior Fellow of the Center for International Security and Cooperation, Freeman Spogli Institute for International Studies, Stanford University; Mark Fitzpatrick, Director of the Nonproliferation and Disarmament Programme, International Institute for Strategic Studies; Sang-Hyun Lee, Director of Security Strategy, Sejong Institute; and Man-Sung Yim, Professor of Nuclear and Quantum Engineering, KAIST.
At the conference, Professor Yim, Director of KAIST NEREC said, “Korea has grown to become a key player in the development of commercial nuclear energy over the past decades. We hope that our conference encourages Korea to be more involved in the efforts of the international community to enhance the global nonproliferation regime.”
2014.08.05 View 14465 -
Professor Min Hyuk Kim Appointed an Associate Editor on ACM Transactions on Graphics
Professor Min Hyuk Kim of KAIST's Computer Science Department has been appointed an associate editor for a prestigious international journal in the field of graphics, ACM Transactions on Graphics (TOG).
Founded in 1947, the Association for Computing Machinery (ACM) is the world’s largest educational and scientific computing society, delivering knowledge that advances computing as a science and profession.
Published during the past 35 years, ACM TOG is a highly regarded, peer-reviewed scientific journal that aims to disseminate the latest findings of research in computer graphics. Professor Kim is the first Korean scholar to serve the journal as an editor.
Professor Kim’s responsibilities are many, and they include selecting appropriate reviewers for submitted manuscripts to be published in the journal and reporting the results of review process.
He said, “The appointment was a great honor, and I’m looking forward to having the opportunity to make further contributions to the advancement of the graphics field.”
Professor Kim has published numerous papers on computer graphics with a focus on research in 3D imaging spectroscopy and visual perception.
2014.07.14 View 10557 -
Artificial Antibody-based Therapeutic Candidate for Lung Cancer Developed
Professor Hak-Sung Kim of Biological Sciences at KAIST publishes a cover article on artificial antibody in "Molecular Therapy".
Repebody-based lung cancer therapeutic drug candidate developed Repebody-based protein demonstrates the possibility of the development of a new drug
KAIST Biological Sciences Department’s Professor Hak-Sung Kim, in collaboration with Professor Eun-Kyung Cho from the College of Medicine at Chungnam National University, has successfully developed an artificial antibody-based, or repebody, cancer therapeutic candidate. These research results were published as a cover paper of the July edition of Molecular Therapy.
The repebody developed by Professor Kim and his team strongly binds to interleukin-6, a cancer-causing factor. It has also been confirmed that the repebody can significantly inhibit the proliferation of cancer cells in non-small-cell lung cancer animal model.
Numerous multinational pharmaceutical and biotechnology companies have invested astronomical amounts of money in research for the development of protein therapeutics with low side effects and high efficacy. More than 20 kinds of such therapeutics are currently under clinical trials, and over 100 drugs are under clinical demonstration. Among these, the majority is antibody-based therapeutics, and most of the investments are heavily concentrated in this field. However, antibody production cost is very high because it has large molecular weights and complex structural properties, and this makes it difficult to engineer. Consequently, the development costs a great deal of time and money.
In order to overcome the existing limitations of antibody-based therapeutics, Professor Kim and his team have developed a new artificial antibody, or repebody, which was published in Proceedings of the National Academy of Sciences (PNAS) in 2012. Based on this research, they have succeeded in developing a therapeutic candidate for treating non-small-cell lung cancer with a specifically strong cohesion to the cancer-causing factor, interleukin-6.
Interleukin-6 is a crucial substance within the body that is involved in immune and inflammatory-related signals. When abnormally expressed, it activates various carcinogenic pathways and promotes tumor growth and metastasis. Because of its importance, multinational pharmaceutical companies are heavily investing in developing therapeutics that can inhibit the signaling of interleukin-6.
In this study, Professor Kim and his team observed that a repebody consists of repeated modules, and they conceived a module-based affinity amplification technology that can effectively increase the binding affinity with the disease target. The developed therapeutic candidate has been confirmed in cell and animal experiments to show low immunogenicity, as well as to strongly inhibit the proliferation of non-small-cell lung cancer.
Furthermore, by investigating the complex structure of the repebody with interleukin-6, Professor Kim has identified its mechanism, which demonstrated the potential for therapeutic development. The researchers are currently carrying out pre-clinical trials for acquiring permission to perform clinical trials on animals with non-small-cell lung cancer. The repebody can be developed into a new protein drug after demonstrating its safety and efficacy.
Professor Hak-Sung Kim and his team have confirmed that the repebody can be utilized as a new protein drug, and this will be a significant contribution to Korea’s protein drugs and biotechnology industry development.
The research was supported by the Future Pioneer Industry project and sponsored by the Ministry of Science, ICT and Future Planning.
Figure 1. Professor Kim’s article published as the cover article of July edition of Molecular Therapy
Figure 2. Clinical proof of the repebody’s inhibition of cancer growth using animal models
2014.07.14 View 13420 -
Professor Haeng-Ki Lee appointed as "ICCES Distinguished Fellow"
Professor Haeng-Ki Lee
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering at KAIST has been appointed as “Distinguished Fellow” and has also received the “Outstanding Research Award” at the International Conference on Computational & Experimental Engineering and Sciences (ICCES).
Founded in 1986, ICCES is regarded as one of the most prestigious international conferences in the field of computational mechanics and experimental engineering.
The Nominating Committee at ICCES recommends the appointment of a distinguished member who has made significant contributions to the development of computational mechanics and experimental engineering. Professor Lee was the first Korean who received such title. Furthermore, he was the recipient of the “Outstanding Research Award” presented by ICCES for his academic research on damage mechanics of complex systems.
Professor Lee is currently serving as the Head of the Department of Civil and Environmental Engineering at KAIST and the Director of BK Plus Agency, a Korean government’s research program. He received an award from the Minister of Science, ICT and Future Planning in 2013 for the promotion of science and technology.
2014.07.02 View 11976 -
KAIST doctoral student wins prize at 2014 International Military Science and Technology Fair
Min-Kyu Yoo (far left), a doctoral student in the Department of Materials Science Engineering, KAIST, received a silver prize at the 2014 International Military Science and Technology Fair held from May 29 to June 1, 2014 at KINTEX, Ilsan City, Korea.
Yoo presented a paper on aluminum composite materials that were reinforced by carbon nanotubes. Carbon nanotubes reinforced aluminum composite materials have strong mechanical properties, and some nations have used them to manufacture battle tanks.
Aluminum generates hydrogen in an alkaline solution. Utilizing this property and the galvanic corrosion of carbon nanotubes and aluminums, Yoo developed a hydrogen energy system that is fueled with composite materials of carbon nanotube reinforced aluminum. He produced 5 kW electric power and maintained it 22 days using 10 kg of the composite materials for a proton exchange membrane fuel cell and its auxiliary power system.
Yoo’s research will alleviate the difficulty of transporting fuels during wartime and can be applied to the development of an auxiliary power system for next generation aircrafts and battle tanks.
2014.06.24 View 9414 -
Professor Sung Yong Kim Appointed as Committee Member to Serve PICES
The Pacific International Council for the Exploration of the Sea: North Pacific Marine Science Organization (PICES) is an intergovernmental organization, which was established in 1992 to promote and coordinate marine research in the North Pacific and adjacent areas. Currently, the United States, Canada, Japan, China, Russia, and Korea are members of the organization.
Professor Sung Yong Kim of Ocean Systems Engineering, KAIST, has been appointed to serve the Scientific and Technical Committees of PICES. He will begin his stint from July 1, 2014. During his assignment, Professor Kim will identify the need for observation of the North Pacific marine environment, develop observation methodology, and publish an annual report on the observation.
Professor Kim is an expert in marine physics and environmental fluids, with a focus on coastal circulation and dynamics, mesoscale and submesoscale eddies, integrated coastal ocean observing system, and statistical and dynamic data analysis.
2014.06.18 View 9102 -
Immune Evasion Mechanism of Hepatitis C Virus Revealed
Professor Ui-Cheol Shin
Inhibiting major histocompatibility complex [MHC] class I protein expression, T cell immune response is evaded.
The research will be a great help to the development of C hepatitis vaccine.
Roughly 1-2% of the population in Korea is known to be infected with Hepatitis C. Most Hepatitis C Virus (HCV) infections progress to a chronic disease and can cause liver cirrhosis or liver cancer, which may lead to death.
Unlike Hepatitis type A or B, there is no vaccine for Hepatitis C Virus and therefore avoiding exposure to the virus is the best known method of prevention. However, a team of researchers at KAIST has produced research results, which may contribute significantly to the vaccine development.
KAIST Graduate School of Medical Sciences & Engineering’ Professor Ui-Cheol Shin and his team have successfully identified why Hepatitis C Virus does not cause an immune response within the human body. The research results were published in the May edition of The Journal of Gastroenterology, a world-renowned journal in the field of gastroenterology.
The immune response occurs to eliminate the virus that has invaded our body. During this process, a major histocompatibility complex [MHC] class I plays a key role in inducing T cell response, which is needed for the elimination of virus-infected cells.
When a cell is infected by a virus, a substance called interferon causes the increased expression of major histocompatibility complex class I. T cell recognizes the increased MHC class I and therefore finds the virus-infected cells.
However, the effect that Hepatitis C Virus has on major histocompatibility complex class I has not been clearly identified until now.
The research team has revealed, using a cell culture for infection systems, that the Hepatitis C Virus suppresses the expression of major histocompatibility complex class I. Also, the mechanism to prove that HCV activates a protein called PKR within the cell to inhibit MHC class I protein expression was identified at a molecular level.
In this study, researchers established the hypothesis that regulating PKR protein in the cell can enhance the T cell immune response, which was then proved through experiments.
Professor Ui-Cheol Shin said, “There are a lot of new drugs to treat Hepatitis C Virus, while its vaccine has not been developed yet. Revealing the HCV immune evasion mechanism will help stimulate momentum for the HCV vaccine development.”
The first author of the journal, Dr. Won-Seok Kang is a graduate from Yonsei College of Medicine. After earning his medical degree, he has continued his training as a ‘doctor-scientist’ at KAIST Graduate School of Medical Sciences & Engineering to study Hepatitis C Virus immune evasion mechanism in this research.
Hepatitis C Virus activates PKR-eIF2a pathway, which inhibits the major histocompatibility complex class I, and therefore weakens the T cell activation to the viral activity.
2014.05.19 View 11267 -
SPIE (The International Society for Optics and Photonics): Scattering Super-lens
The International Society for Optics and Photonics (SPIE), dedicated to advancing an interdisciplinary approach to the science and application of light, published online a short paper authored by a KAIST research team, Dr. Jung-Hoon Park and Professor YongKeun Park of Physics, introducing a new optical technology to observe sub-wavelength light by exploiting multiple light scattering in complex media.
For the article, please go to the link below:
SPIE: Nanotechnology
May 7th, 2014
"Scattering superlens" by Jung-Hoon Park and YongKeun Park
http://spie.org/x108298.xml
2014.05.14 View 7563