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Professor Kwang-Hyun Cho Recognzied by "Scientist of the Month" Award
Professor Kwang-Hyun Cho of KAIST’s Department of Bio and Brain Engineering received the “Scientist of the Month” award in February 2015 from the Ministry of Science, ICT, and Future Planning of the Republic of Korea and the National Research Foundation of Korea. The award was in recognition of Professor Cho’s contribution to the advanced technique of controlling the death of cancer cells based on systems biology, a convergence research in information technology (IT) and biotechnology. Professor Cho has published around 140 articles in international journals, including 34 papers in renowned science journals such as Nature, Science, and Cell in the past three years. His work also includes systems biology textbooks and many entries in international academic encyclopaedia. His field, systems biology, is a new biological research paradigm that identifies and controls the fundamental principles of organisms on a systems level. A well-known tumour suppressor protein, p53, is known to suppress abnormal cell growth and promote apoptosis of can cells, and thus was a focus of research by many scientists, but its effect has been insignificant and brought many side effects. This was due to the complex function of p53 that controls various positive and negative feedbacks. Therefore, there was a limit to understanding the protein with the existing biological approach. However, Professor Cho found the kinetic change and function of p53 via a systems biology approach. By applying IT technology to complex biological networks, he also identified the response to stress and the survival and death signal transduction pathways of cardiomyocytes and developed new control methods for cancer cells. Professor Cho said, “This award served as a momentum to turn over a new leaf.” He added, “I hope convergence research such as my field will bring more innovative ideas on the boundaries of academia.”
2015.02.09
View 10048
KAIST wins second place in unmanned boat competition
KAIST took second place in an international competition to promote technologies of the autonomous underwater vehicle (AUV). Professor Jin-hwan Kim’s research team from KAIST’s Ocean Systems Engineering Department won the second place in Maritime RobotX Challenge which took place for the first time from October 20 - 26 in Marina Bay, Singapore. Along with automobiles and drones, the necessity for unmanned boats has grown. To encourage and examine the development of these technologies, the U.S. Office of Naval Research decided to organize an unmanned boat competition which took place for the first time this year. After three teams were selected from a domestic competition in each countries, a total of fifteen teams from five countries from the Pacific Rim including Korea, the United States, Australia, Japan, and Singapore competed. Teams from such universities as MIT, Tokyo University, Tokyo Institute of Technology, National University of Singapore, Nanyang Technological University, and Queensland University of Technology participated. In addition to KAIST, Seoul National University and Ulsan University participated. Using a 4.5 meters long and 2.5 meters wide unmanned boat provided by the organizer, each team had to implement an integrated system that combined a propulsion system, hardware, and autonomous software. Each team’s vessel had to perform tasks without manual control, employing autonomous driving through recognition of the course, searching underwater for acoustic sources, automatically approaching piers, remote observation of buoy, and avoidance and detection of obstacles. Although KAIST outpaced MIT in the semifinal which selected six out of fifteen teams, it won the second place in the final. As well as winning second prize, KAIST also won best website prize and a special prize from the competition sponsor, Northrop Grumman Corporation, an American defense technology company, totaling 16,500 U.S. dollars of prize money. The Vice President for Planning and Budget, Professor Seungbin Park said, “It was a great opportunity to showcase the advanced unmanned robot technology of Korea.” He added that “this raised KAIST’s reputation as a global research oriented university.” Professor Kim commented, “Along with automobiles and drones, the necessity for the development of unmanned ocean vehicles such as unmanned boats and submarines are recognized these days.” He added that “the use of unmanned boats will make the process of channel investigation, ocean exploration, surveillance over water territories safer and more effective.” Professor Kim’s team was sponsored by the U.S. Office of Naval Research, Samsung Heavy Industries, Sonar Tech, Daeyang Electric, and Red-one Technology. KAIST Team's Unmanned Boat The Competition's Missions
2014.12.12
View 8909
Nanoparticle Cluster Manufacturing Technique Using DNA Binding Protein Developed
Professor Hak-Sung Kim of the Department of Biological Sciences at KAIST and Yiseul Ryu, a doctoral candidate, used the Zinc Finger protein that specifically binds to target DNA sequence to develop a new manufacturing technique for size-controllable magnetic Nanoparticle Clusters (NPCs). Their research results were published in Angewandte Chemie International Edition online on 25 November 2014. NPCs are structures consisting of magnetic nanoparticles, gold nanoparticles, and quantum dots, each of which are smaller than 100 nm (10-9m). NPCs have a distinctive property of collectivity not seen in single nanoparticles. Specifically NPCS differ in physical and optical properties such as Plasmon coupling absorbance, energy transfers between particles, electron transfers, and conductivity. Therefore, NPCs can be employed in biological and medical research as well as the development of nanoelectric and nanoplasmon devices. To make use of these novel properties, the size and the composition of the cluster must be exquisitely controlled. However, previous techniques relied on chemical binding which required complex steps, making it difficult to control the size and composition of NPCs. Professor Kim’s team used Zinc Finger, a DNA binding protein, to develop a NPCs manufacturing technique to create clusters of the desired size easily. The Zinc Finger protein contains a zinc ion and specifically recognizes DNA sequence upon binding, which allows the exquisite control of the size and the cluster composition. The technique is also bio-friendly. Professor Kim’s team created linear structure of different sizes of NPCs using Zinc Finger proteins and three DNA sequences of different lengths. The NPCs they produced confirmed their ability to control the size and structure of the cluster by using different DNA lengths. The NPCs showed tripled T2 relaxation rates compared to the existing MRI contrast media (Feridex) and effectively transported to targeted cells. The research findings show the potential use of NPCs in biological and medical fields such as MRI contrast media, fluorescence imaging, and drug transport. The research used the specific binding property of protein and DNA to develop a new method to create an inorganic nanoparticle’s supramolecular assembly. The technique can be used and applied extensively in other nanoparticles for future research in diagnosis, imaging, and drug and gene delivery. Figure 1. A Mimetic Diagram of NPCs Manufacturing Technique Using DNA Binding Protein Zinc Finger Figure 2. Transmission Electron Microscopy Images showing different sizes of NPCs depending on the length of the DNA
2014.12.04
View 10596
The Bio-Synergy Research Center, KAIST, Hosts an Annual Meeting
The Ministry of Science, ICT and Future Planning of the Republic of Korea founded the Bio-Synergy Research Center (BSRC) at KAIST in 2013 to develop source technology and generate new knowledge by conducting convergence research projects in natural resources with information technology (IT) and biotechnology. The BSRC hosted an annual meeting on November 21, 2014, at the KAIST campus and reviewed the progress it made this year with the participation of President Steve Kang of KAIST, Commissioner Young-min Kim of KIPO, and Director Doheon Lee of BSRC. The Korean Intellectual Property Office (KIPO) provided BSRC with its database in Korean traditional medicine that includes a vast amount of information about disease symptoms, native medicinal herbs and plant extracts, prescriptions, and chemical compounds used for medication. The database, “Compound Combination-Oriented Natural Product Database with Unified Terminology (COCUNUT),” holds approximately one million data sets in four major categories: prescriptions, medicinal resources, medicine components and functions, and diseases. Based on COCUNUT, BSRC has been working on the standardization of Korean traditional medicine such as the development of data mapping and text mining technology and the analysis of big data in accordance with the said categories. Using IT and biotechnology, the center has also created a virtual human body to explain how traditional medicine works in human body, thereby contributing to the development of new natural materials for medicine.
2014.12.03
View 6711
Professor Joong-Keun Park Receives SeAH Heam Academic Award
Professor Joong-Keun Park of the Department of Materials Science and Engineering at KAIST received an award from SeAH Steel Corp. in recognition of his academic achievements in the field of metallic and materials engineering. The award was presented at the 2014 Fall Conference of the Korean Institute of Metals and Materials which took place on October 22-24 at the Kangwon Land Convention Hotel. The award, called “SeAH Heam Academic Award,” is given annually to a scholar who has contributed to the development of new metal and polymer composite materials and its related field in Korea. Following the award ceremony, Professor Park gave a keynote speech on ferrous metals for automotive materials.
2014.11.04
View 6709
The 2014 SoC Robot Competition Took Place
Professor Hoi-Jun Yoo of the Department of Electrical Engineering at KAIST and his research team hosted a competition for miniature robots with artificial intelligence at KINTEX in Ilsan, Korea, on October 23-26, 2014. The competition, called the 2014 SoC Robot War, showed the latest developments of semiconductor and robot technology through the robots’ presentations of the Korean martial art, Taekwondo, and hurdles race. SoC is a system on ship, an integrated circuit that holds all components of a computer or other electronic systems in a single chip. SoC robots are equipped with an artificial intelligence system, and therefore, can recognize things on their own or respond automatically to environmental changes. SoC robots are developed with the integration of semiconductor technology and robotics engineering. Marking the thirteenth competition this year since its inception, the Robot War featured two competitions between HURO and Taekwon Robots. Under the HURO competition, participating robots were required to run a hurdle race, pass through barricades, and cross a bridge. The winning team received an award from the president of the Republic of Korea. Robots participating in the Taekwon Robot competition performed some of the main movements of Taekwondo such as front and side kicks and fist techniques. The winning team received an award from the prime minster of the Republic of Korea. A total of 105 teams with 530 students and researchers from different universities across the country participated in preliminaries, and 30 teams qualified for the final competition.
2014.10.27
View 6926
PIBOT, a small humanoid robot flies an aircraft
The 2014 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2014) took place in Chicago, Illinois, on September 14-18, 2014. Professor David Hyunchul Shim and his students from the Department of Aerospace Engineering, KAIST, presented a research paper entitled “A Robot-machine Interface for Full-functionality Automation Using a Humanoid” at the conference. The robot called “PIBOT,” a pint-sized, tiny humanoid robot, uses a mixture of flight data and visuals to fly an airplane, capable of identifying and operating all of the buttons and switches in the cockpit of a normal light aircraft designed for humans. For now, the robot is only flying a simulator, but Professor Shim expects that “PIBOT will help us have a fully automated flight experience, eventually replacing human pilots.” The IEEE Spectrum magazine published an article on PIBOT posted online September 18, 2014. Please follow the link below for the article: IEEE Spectrum, September 18, 2014 Tiny Humanoid Robot Learning to Fly Real Airplanes http://spectrum.ieee.org/automaton/robotics/humanoids/tiny-humanoid-robot-learning-to-fly-real-airplanes
2014.09.23
View 11023
Distinguished Professor Sang Yup Lee Participates in the 2014 Summer Davos Forum
Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering, KAIST, was invited to lead four sessions at the Annual Meeting 2014, the World Economic Forum, also known as the Summer Davos Forum, which was held in Tianjin, China, from September 10th to 12th. Two of the four sessions Professor Lee participated in were held on September 10th. At the first session entitled “Biotechnology Ecosystem,” he examined with other panelists the future of bioengineering in depth and discussed major policies and industry trends that will be necessary for the development of future biotechnologies. Professor Lee later attended the “Strategic Shifts in Healthcare” session as a moderator. Issues related to transforming the health industry such as the next-generation genomics, mobile health and telemedicine, and wearable devices and predictive analytics were addressed. On September 12, Professor Lee joined the “IdeasLab with KAIST” and gave a presentation on nanotechnology. There was a total of ten IdeasLab sessions held at the Summer Davos Forum, and KAIST was the only Korean university ever invited to host this session. In addition to Professor Lee’s presentation, three more presentations were made by KAIST professors on such topics as “Sustainable Energy and Materials” and “Next-generation Semiconductors.” Lastly, Professor Lee participated in the “Global Promising Technology” session with the World Economic Forum’s Global Agenda Council members. At this session, he explained the selection of the “World’s Top 10 Most Promising Technologies” and “Bio Sector’s Top 10 Technologies” and led discussions about the “2015 Top 10 Technologies” with the council members. The Davos Forum has been announcing the “World’s Top 10 Most Promising Technologies” since 2012, and Professor Lee has played a key role in the selection while working as the Chairman of Global Agenda Council. The selection results are presented at the Davos Forum every year and have attracted a lot of attention from around the world.
2014.09.15
View 8971
News Article on the Development of Synthesis Process for Graphene Quantum Dots
Before It's News, an international online news agency, highlighted the recent research conducted by KAIST professors (Seokwoo Jeon of the Department of Materials Science and Engineering, Yong-Hoon Cho of the Department of Physics, and Seunghyup Yoo of the Department of Electrical Engineering) on the development of synthesis process for graphene quantum dots, nanometer-sized round semiconductor nanoparticles that are very efficient at emitting photons. If commercialized, this synthetic technology will lead the way to the development of paper-thin displays in the future. For the article, please go to the link below: Before It’s News, September 3, 2014“Graphene quantum dots prove highly efficient in emitting light” http://beforeitsnews.com/science-and-technology/2014/09/graphene-quantum-dots-prove-highly-efficient-in-emitting-light-2718190.html
2014.09.07
View 10075
Extracting Light from Graphite: Core Technology of Graphene Quantum Dots Display Developed
Professor Seokwoo Jeon of the Department of Materials Science and Engineering, Professor Yong-Hoon Cho of the Department of Physics, and Professor Seunghyup Yoo of the Department of Electrical Engineering announced that they were able to develop topnotch graphene quantum dots from graphite. Using the method of synthesizing graphite intercalation compound from graphite with salt and water, the research team developed graphene quantum dots in an ecofriendly way. The quantum dots have a diameter of 5 nanometers with their sizes equal and yield high quantum efficiency. Unlike conventional quantum dots, they are not comprised of toxic materials such as lead or cadmium. As the quantum dots can be developed from materials which can be easily found in the nature, researchers look forward to putting these into mass production at low cost. The research team also discovered a luminescence mechanism of graphene quantum dots and confirmed the possibility of commercial use by developing quantum dot light-emitting diodes with brightness of 1,000 cd/m2, which is greater than that of cellphone displays. Professor Seokwoo Jeon said, “Although quantum dot LEDs have a lower luminous efficiency than existing ones, their luminescent property can be further improved” and emphasized that “using quantum dot displays will allow us to develop not only paper-thin displays but also flexible ones.” Sponsored by Graphene Research Center in KAIST Institute for NanoCentury, the research finding was published online in the April 20th issue of Advanced Optical Materials. Picture 1: Graphene quantum dots and their synthesis Picture 2: Luminescence mechanism of graphene quantum dots Picture 3: Structure of graphene quantum dots LED and its emission
2014.09.06
View 13830
2014 NEREC Conference on Nuclear Nonproliferation: July 31-August 1, 2014, Seoul
The Nonproliferation Education and Research Center (NEREC) at KAIST hosted an international conference on nuclear nonproliferation on July 31-August 1, 2014 in Seoul. The Ministry of Science, ICT and Future Planning, the Korean Nuclear Safety and Security Commission, and the Korea Nuclear Policy Society (KNPS) sponsored the event. Over one hundred experts and "thought leaders" in nuclear security and nonproliferation attended the conference and discussed issues related to the nonproliferation of nuclear weapons, the role of scientific community in mitigating nuclear threat and promoting the peaceful use of nuclear power, and nuclear disarmament policy. Keynote speakers were: Steven E. Miller, Director of International Security Program at Belfer Center for Science and International Affairs, Harvard University; Scott D. Sagan, Senior Fellow of the Center for International Security and Cooperation, Freeman Spogli Institute for International Studies, Stanford University; Mark Fitzpatrick, Director of the Nonproliferation and Disarmament Programme, International Institute for Strategic Studies; Sang-Hyun Lee, Director of Security Strategy, Sejong Institute; and Man-Sung Yim, Professor of Nuclear and Quantum Engineering, KAIST. At the conference, Professor Yim, Director of KAIST NEREC said, “Korea has grown to become a key player in the development of commercial nuclear energy over the past decades. We hope that our conference encourages Korea to be more involved in the efforts of the international community to enhance the global nonproliferation regime.”
2014.08.05
View 10410
The First Demonstration of a Self-powered Cardiac Pacemaker
As the number of pacemakers implanted each year reaches into the millions worldwide, improving the lifespan of pacemaker batteries has been of great concern for developers and manufacturers. Currently, pacemaker batteries last seven years on average, requiring frequent replacements, which may pose patients to a potential risk involved in medical procedures. A research team from the Korea Advanced Institute of Science and Technology (KAIST), headed by Professor Keon Jae Lee of the Department of Materials Science and Engineering at KAIST and Professor Boyoung Joung, M.D. of the Division of Cardiology at Severance Hospital of Yonsei University, has developed a self-powered artificial cardiac pacemaker that is operated semi-permanently by a flexible piezoelectric nanogenerator. The artificial cardiac pacemaker is widely acknowledged as medical equipment that is integrated into the human body to regulate the heartbeats through electrical stimulation to contract the cardiac muscles of people who suffer from arrhythmia. However, repeated surgeries to replace pacemaker batteries have exposed elderly patients to health risks such as infections or severe bleeding during operations. The team’s newly designed flexible piezoelectric nanogenerator directly stimulated a living rat’s heart using electrical energy converted from the small body movements of the rat. This technology could facilitate the use of self-powered flexible energy harvesters, not only prolonging the lifetime of cardiac pacemakers but also realizing real-time heart monitoring. The research team fabricated high-performance flexible nanogenerators utilizing a bulk single-crystal PMN-PT thin film (iBULe Photonics). The harvested energy reached up to 8.2 V and 0.22 mA by bending and pushing motions, which were high enough values to directly stimulate the rat’s heart. Professor Keon Jae Lee said: “For clinical purposes, the current achievement will benefit the development of self-powered cardiac pacemakers as well as prevent heart attacks via the real-time diagnosis of heart arrhythmia. In addition, the flexible piezoelectric nanogenerator could also be utilized as an electrical source for various implantable medical devices.” This research result was described in the April online issue of Advanced Materials (“Self-Powered Cardiac Pacemaker Enabled by Flexible Single Crystalline PMN-PT Piezoelectric Energy Harvester”: http://onlinelibrary.wiley.com/doi/10.1002/adma.201400562/abstract). Youtube link: http://www.youtube.com/watch?v=ZWYT2cU_Mog&feature=youtu.be Picture Caption: A self-powered cardiac pacemaker is enabled by a flexible piezoelectric energy harvester.
2014.06.25
View 14235
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