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MoU by KAIST-Seoul-Seocho-gu for the 4th Industrial Revolution
The opening ceremony of the Yangjae R&CD Innovation Hub was held in Seoul on December 5. More than 400 guests came to the ceremony from major institutes and companies that are based in the hub. KAIST President Sung-Chul Shin, the Mayor of Seoul, Won-soon Park, and the Mayor of Seocho-gu, Eun Hee Cho, signed an MoU for Seoul to be the leading city for successfully realizing the Fourth Industrial Revolution. The three organizations aim to cooperate with one another in various areas, including an economic boost for local job creation, technology development, and the promotion of projects through an industry-academia-institute network and fostering manpower. Yangjae R&CD is the first facility specializing in and dedicated for Artificial Intelligence, which is the major topic of the Fourth Industrial Revolution. The hub is comprised of enterprises specializing in AI, open co-work spaces, conference rooms, an open networking lounge, and spaces for fostering professional manpower. The hub will recruit additional enterprises and individuals who wish to move in. KAIST, an institute containing professors and researchers in the field of AI, and Modulabs, an organization becoming distinguished in AI research, will be in charge of operating the facility together. The Yangjae R&CD Innovation Hub will operate a professional training program with participation from KAIST professors, which aims to produce 500 professionals in AI research and development by 2020. It will also provide inexpensive space as well as consultations and venture capital to startup and venture companies. It plans to find and foster 50 innovation companies by 2020. In particular, the hub will operate a course for new AI business models 24 times over three years. The hub also offers job consultations, academic conferences, public space for companies residing in the hub, a free GPU cluster server, technical training, seminars, forums, investment attraction, overseas expansion, and one-to-one technical consultations. The Yangjae R&CD Zone is the place established for the Fourth Industrial Revolution by Seoul. R&CD is a concept combining Research and Development, Connection, Companies, Community, and Culture. Seoul aims to create the Yangjae Zone as an urban innovation hub for facilitating industry-academia linkage as well as establishing a startup-settlement-growth technical ecosystem.
Professor Lee's Research Selected as Top 100 National R&D Projects
A research project, led by Research Professor Ju Yong Lee from the KAIST Institute for IT Convergence, was selected as one of the Top 100 National Research and Development Projects 2017. This research project, titled LTE-A-based Single RF Small Base Station supporting Multiple Streams, developed 300Mbps low power, low complexity and broadband small base station technology that supports 4x4 MIMO (Multiple Input and Multiple Output) by proposing a new antenna structure and a new RF (Radio Frequency) structure based on LTE-A. Professors from the School of Electrical Engineering at KAIST, Dong Ho Cho, Songcheol Hong, and Yong Hoon Lee also collaborated on the project. The existing heterodyne method of communication systems generates the problems of increasing unit price and system complexity. In this project, however, Professor Lee directly modulated the baseband signal from the RF stage through an impedance loading-based RF chip. This method was designed to facilitate low power as well as low complexity while supporting broadband service. Based on this, his team developed source technology for RF that can be applied to fourth and even fifth generation networks. Furthermore, this base station is smallest among the small-cell stations so far, providing an eco-friendly installation environment. It contributes to the market for fifth generation mobile communications by reducing power consumption significantly yet providing high-capacity services. Professor Lee said, “This technology will contribute to creating a new market and additional jobs because business based on the fifth mobile generation can provide multi-functional services, including multiband. Requiring low power and providing high-capacity services anywhere at any time will enhance national competence and reduce costs for establishing a next generation mobile communication system. It is expected that this technology will help with disseminating mobile communication infrastructure through expanding information and communication system as well as the infrastructure of island areas.”
More Donations Arrive to Establish the New Medicine Research and Development Center on Campus
A raft of businesses continues to make donations to establish a new medicine research and development center on campus. The Department of Biological Sciences at KAIST is leading the fundraising campaign. On November 9, 2015, Nikon Instruments Korea Co., Ltd. contributed USD 8,500 to the fundraising, followed by Carl Zeiss AG and Three-Shine Inc., which donated USD 12,800 and 8,500, respectively. Bruno Lin, an Executive Director at Carl Zeiss AG in Korea, said, “I’m very glad to participate in this fundraising initiative for the Biological Sciences Department at KAIST, one rapidly reaching out to the world.” From the left in the picture are Vice President Tae-Hoon Kim, Director Gyu-Hyeok Lee, and Executive Director Bruno Lin of Carl Zeiss AG, Byung-Ha Oh, Dean of the Biological Sciences Department, and Professor Eunjoon Kim. From the left in the picture are Byung-Ha Oh, Dean of the Biological Sciences Department, President Chun-Gui Park of Three-Shine Inc., and Professor Daesoo Kim. President Chun of Three-Shine Inc., said, “We hope that the Department of Biological Sciences at KAIST, aided by the construction of new research center, will produce practical research achievements and stand on the frontier of new medicine development research in Korea.” The New Medicine Research and Development Center will be equipped with state-of-the-art, purpose-built research facilities to support convergent, interdisciplinary research in biomedicine.
KAIST and Oberthur Technologies Agree for Research and Development in Mobile Security
Professor Kwangjo Kim of the School of Computing at KAIST has signed a research and development (R&D) agreement with Marc Bertin, the Chief Technology Officer of Oberthur Technologies (OT), a French security solutions firm, on September 18, 2015 in Paris. Under the agreement, KAIST and OT will conduct joint research on mobile security as well as implement an internship program for KAIST graduate students to work either at OT’s R&D center in Korea or in France. OT has established a research center in Korea in July 2014, which was the fourth of its research centers in Asia. Professor Kim said, “Our goal at KAIST is to cultivate top-level security experts in security technologies. By partnering with such a leader in security technologies as OT, we know that we will both help shape tomorrow’s security solution for the IoT (Internet of Things) space.” In the picture, Professor Kwangjo Kim (left) shakes hands with Marc Bertin, the Chief Technology Officer of Oberthur Technologies (right), after the signing of a memorandum of understanding.
KAIST announced a novel technology to produce gasoline by a metabolically engineered microorganism
A major scientific breakthrough in the development of renewable energy sources and other important chemicals; The research team succeeded in producing 580 mg of gasoline per liter of cultured broth by converting in vivo generated fatty acids For many decades, we have been relying on fossil resources to produce liquid fuels such as gasoline, diesel, and many industrial and consumer chemicals for daily use. However, increasing strains on natural resources as well as environmental issues including global warming have triggered a strong interest in developing sustainable ways to obtain fuels and chemicals. Gasoline, the petroleum-derived product that is most widely used as a fuel for transportation, is a mixture of hydrocarbons, additives, and blending agents. The hydrocarbons, called alkanes, consist only of carbon and hydrogen atoms. Gasoline has a combination of straight-chain and branched-chain alkanes (hydrocarbons) consisted of 4-12 carbon atoms linked by direct carbon-carbon bonds. Previously, through metabolic engineering of Escherichia coli (E. coli), there have been a few research results on the production of long-chain alkanes, which consist of 13-17 carbon atoms, suitable for replacing diesel. However, there has been no report on the microbial production of short-chain alkanes, a possible substitute for gasoline. In the paper (entitled "Microbial Production of Short-chain Alkanes") published online in Nature on September 29, a Korean research team led by Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering at the Korea Advanced Institute of Science and Technology (KAIST) reported, for the first time, the development of a novel strategy for microbial gasoline production through metabolic engineering of E. coli. The research team engineered the fatty acid metabolism to provide the fatty acid derivatives that are shorter than normal intracellular fatty acid metabolites, and introduced a novel synthetic pathway for the biosynthesis of short-chain alkanes. This allowed the development of platform E. coli strain capable of producing gasoline for the first time. Furthermore, this platform strain, if desired, can be modified to produce other products such as short-chain fatty esters and short-chain fatty alcohols. In this paper, the Korean researchers described detailed strategies for 1) screening of enzymes associated with the production of fatty acids, 2) engineering of enzymes and fatty acid biosynthetic pathways to concentrate carbon flux towards the short-chain fatty acid production, and 3) converting short-chain fatty acids to their corresponding alkanes (gasoline) by introducing a novel synthetic pathway and optimization of culture conditions. Furthermore, the research team showed the possibility of producing fatty esters and alcohols by introducing responsible enzymes into the same platform strain. Professor Sang Yup Lee said, "It is only the beginning of the work towards sustainable production of gasoline. The titer is rather low due to the low metabolic flux towards the formation of short-chain fatty acids and their derivatives. We are currently working on increasing the titer, yield and productivity of bio-gasoline. Nonetheless, we are pleased to report, for the first time, the production of gasoline through the metabolic engineering of E. coli, which we hope will serve as a basis for the metabolic engineering of microorganisms to produce fuels and chemicals from renewable resources." This research was supported by the Advanced Biomass Research and Development Center of Korea (ABC-2010-0029799) through the Global Frontier Research Program of the Ministry of Science, ICT and Future Planning (MSIP) through the National Research Foundation (NRF), Republic of Korea. Systems metabolic engineering work was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries (NRF-2012-C1AAA001-2012M1A2A2026556) by MSIP through NRF. Short-Chain Alkanes Generated from Renewable Biomass This diagram shows the metabolic engineering of Escherichia coli for the production of short-chain alkanes (gasoline) from renewable biomass. Nature Cover Page (September 29th, 2013)
Success in differentiating Functional Vascular Progenitor Cells (VPC)
KAIST’s Professor Han Yong Man successfully differentiated vascular progenitor cells from human embryonic stem cells and reversed differentiated stem cells. The research went beyond the current method of synthesis of embryonic body or mice cell ball culture and used the careful alteration of signal transmission system of the human embryonic stem cells to differentiate the formation of vascular progenitor cells. The team controlled the MEK/ERK and BMP signal transmission system that serves an important role in the self replication of human embryonic stem cells and successfully differentiated 20% of the cells experimented on to vascular progenitor cells. The vascular progenitor cells produced with such a method successfully differentiated into cells forming the endodermis of the blood vessel, vascular smooth muscle cells and hematopoietic cells in an environment outside of the human body and also successfully differentiated into blood vessels in nude mice. In addition, the vascular progenitor cell derived from human embryonic cells successfully formed blood vessels or secreted vascular growth factors and increased the blood flow and the necrosis of blood vessels when injected into an animal with limb ischemic illness. The research was funded by the Ministry of Education, Science and Technology, 21st Century Frontier Research and Development Institution’s Cell Application Research Department and Professor Ko Kyu Young (KAIST), Professor Choi Chul Hee (KAIST), Professor Jeong Hyung Min (Cha Medical School) and Doctor Jo Lee Sook (Researcher in Korea Bio Engineering Institute) participated in it. The results of the research was published as the cover paper of the September edition of “Blood (IF:10.55)”, the American Blood Journal and has been patented domestically and has finished registration of foreign PCT. The results of the experiment opened the possibility of providing a patient specific cure using stem cells in the field of blood vessel illness.
President Nam Pyo Suh of KAIST discussed cooperation with KUSTAR on the training of skilled manpower for research and development (R&D)
Representatives from Korea Advanced Institute of Science and Technology (KAIST), Khalifa University of Science, Technology and Research (KUSTAR), Emirate Nuclear Energy Corporation (ENEC), and the Institute of Applied Technology (IAT) had a meeting on mutual cooperation at the Intercontinental Hotel in Abu Dhabi, the United Arab Emirates (UAE), on January 14, 2009. Participants of the meeting were President Nam Pyo Suh of KAIST, President Arif Sultan Al Hammadi of KUSTAR, President Mohamed Al Hammadi of ENEC, and Director General Abdullatif Mohamed Al Shamsi of IAT. A press conference on the training of skilled manpower for research and development (R&D) in the UAE followed afterwards. At the end of December in 2009, a Korean consortium led by Korea Electric Power Corporation (KEPCO) beat bids from its competitors to construct four nuclear power plants in the UAE. Representing the consortium, Minister Kyung Hwan Choi of Knowledge Economy Ministry signed a comprehensive agreement with KUSTAR and the Institute of Applied Technology (IAT) for the delivery of nuclear power plants. On his visit, President Suh discussed with KUSTAR the agreement above in greater detail on subjects, where KAIST renders its cooperation, such as research collaboration, university degree program, and training to produce qualified personnel necessary for the development of UAE’s nuclear energy industry. On research collaboration, sharing its expertise and knowledge accumulated years from the operation of academic and research programs, KAIST agreed to provide cooperation to KUSTAR in developing the latter as a leading science, technology, and research university in ten years through mutual activities such as research collaborations, recruitment and exchange of outstanding researchers and graduate students, expansion of research facilities, and creation of major research policies. Furthermore, in support of nuclear energy program in the UAE, KAIST agreed to develop a joint research program in nuclear engineering and exchange faculty members and students for research collaboration. On a university degree program, KAIST agreed for mutual cooperation to launch academic programs at KUSTAR, covering BSc, MSc, and PhD degrees to specialize in areas such as mechanical engineering, electrical engineering, nuclear engineering, biomedical engineering, nano technology, science, and information technology. To that end, KAIST will dispatch its faculty to KUSTAR; provide assistance in developing curriculum and teaching materials; and exchange students for research collaboration. President Arif of KUSTAR mentioned that the university will cooperate with the relevant institutions in Korea, i.e., Korea Development Institute (KDI) and the Korea Institute of Nuclear Safety (KINS), to train skilled workers required for the development of nuclear energy program in the UAE. He also added, “These cooperative programs will introduce more educational opportunities to our students, and as a result, they can make greater contributions to the development of our nation’s future technologies in various areas. Our students will have a chance to study a broad range of academic subjects through partnership made with the Republic of Korea, and I expect to see improvements in our engineering programs by integrating KAIST’s state-of-the-art academic courses into our system.” President Arif expressed his hope “to increase cooperation beyond the agreement made between the two countries, like allowing more exchanges and interactions with KAIST for the development of science and technology in Korea and the UAE.” “Establishing mutual cooperation between KAIST and KUSTAR is a historic event not only for our two universities but also for our two countries. The two universities will make a great contribution to the improvement of the future of humanity by working together to solve the most important, difficult issues faced in the 21st century,” said President Suh. He also said that “all members of KAIST community will make our utmost efforts to advance the quality of education in two schools and to implement innovative researches through mutual cooperation.” KUSTAR, a national university in the UAE, was founded on February 13, 2007 by a mandate of the current President Shaikh Khalifa Bin Zayed Al Nahyan to create a higher education institute. KUSTAR has been building its permanent campus in Abu Dhabi, the capital of UAE since establishment and merged with the campus in Sharjah (formerly known as Etisalat University College with 18 years of history) in 2008. The University offers education and research programs in five disciplines of engineering, logistics and management, health science, homeland security, and applied science. There are more or less 30 foreign accredited universities set up in the UAE from countries like the US, UK, Australia, France, Ireland, and Canada. Examples of such, among other things, are New York University Abu Dhabi campus and Middlesex University Dubai campus. Many of the foreign universities in the UAE, however, have colleges of pharmacy, computer science, aviation, management information, fashion design, business management, and medical science including Harvard Medical School Dubai Center, but not many in science and research. Therefore, KAIST’s assistance in KUSTAR’s endeavor to become a leading science and research university in the UAE is timely. The current government of UAE anticipates, with a great interest, to see a leading science and research intuition built in their nation. Attachment: Current Status of Universities in the UAE as of 2009 Background Information The United Arab Emirates (UAE) is a federation of seven emirates (Abu Dhabi, Dubai, Sharjah, Ajman, Umm al-Quwain, Ras al-Khaimah, and Fujairah) situated on the Arabian Peninsula, which borders with Oman and Saudi Arabia. The UAE has the world"s sixth largest oil reserves. As of 2008, its gross domestic product is $2,621,000.5 million and its nominal per capita gross domestic product is $5 5,028, becoming one of the most developed economies in the Middle East. The UAE’s total population as of the said year is 4,760.4 thousand, and its purchasing power per capita is 40th largest in the world. The UAE’s Human Development Index for Asian continent is relatively high, ranking 31st globally. In 1985, the UAE launched its own airline, Emirates Airline, which has become one of the fastest growing airlines in the world. The Emirates Airline is a sponsor for Arsenal soccer club. The Republic of Korea established full diplomatic relations with the UAE in June of 1980. On December 27, 2009, a Korean consortium led by Korea Electrical Power Corporation (KEPCO) signed a contract with the UAE to build nuclear power plants.
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