Accurate Real time ECG Measurement While Comfortably Lying Down at Home
< (From left) Professor Chul Kim of the Department of Bio and Brain Engineering, Ph.D. candidate Minjae Kim, researcher Premravee Teeravichayangoon >
KAIST's research team has developed a technology that can measure electrocardiogram (ECG) and heart rate variability (HRV) in real time by simply lying on a bed with clothes on, without having to go to the hospital. This technology is expected to evolve into a daily heart health monitoring platform in conjunction with remote healthcare, and further expand into various bio-healthcare fields such as sleep and stress analysis, contributing to personalized prevention and early diagnosis for patients.
KAIST announced on the 19th that Professor Chul Kim's research team from the Department of Bio and Brain Engineering has developed an 'in-bed cardiac monitoring on-device system'.
The research team manufactured a flexible substrate sensor that integrates the electronic circuit and electrodes into one to increase precision, and implemented an integrated system that can perform signal-noise separation, heart beat signal (R-peak) detection, and heart rate variability analysis in real time through on-device signal processing.
Existing ECG measurement had the inconvenience of visiting a hospital, taking off clothes, and attaching wet electrodes to the skin. Because of this, long-term monitoring was difficult, and it was not easy for the elderly or patients with chronic diseases to use it daily. Non-contact methods also had a technical limitation of being vulnerable to external noise.
To solve these problems, the research team applied a circuit that blocks external noise (active shielding) and a circuit that stably captures minute current changes in the human body (right-leg drive circuit). In addition, they implemented a mathematical transformation technique (wavelet transform) that extracts only the important parts from the heart beat signal and a calculation method (peak detection algorithm) that accurately identifies the moment of the heart's electrical beat (R-peak) as on-device signal processing techniques, allowing for precise real-time analysis of the signal.
As a result, users can obtain stable and accurate ECG signals even when lying on their backs with clothes on.
< Figure. Overall structural diagram of the developed non-contact in-bed cardiac monitoring on-device system, schematic diagram of the R-peak detection algorithm, real-time ECG and HRV measurement screen >
This research presents new possibilities for managing chronic cardiovascular diseases and supporting the health of the elderly, as it can be easily used not only in hospitals but also at home.
Professor Chul Kim said, "This system, which can extract signals in real time even in a noisy environment, can be used to easily check heart health in daily life," and added, "In the future, it will become the foundation of sleep health management by adding the measurement of various bio-signals."
This paper, in which Ph.D. candidate Minjae Kim and researcher Premravee Teeravichayangoon from the Department of Bio and Brain Engineering participated as co-first authors, was published online in the international journal 'Biosensors and Bioelectronics' on August 9, 2025.
※ Paper title: A homecare in-bed hardware system for precise real-time ECG and HRV monitoring with layered clothing. DOI: https://doi.org/10.1016/j.bios.2025.117838
※ Author information: Minjae Kim (KAIST Department of Bio and Brain Engineering, First Author), Premravee Teeravichayangoon (KAIST Department of Bio and Brain Engineering, First Author), Chul Kim (KAIST Department of Bio and Brain Engineering, Corresponding Author)
Meanwhile, this research was carried out with the support of the National Research Foundation of Korea's Basic Research Lab and Bio-medical Technology Development Project, and the KAIST-Ceragem Future Healthcare Research Center.
Low Cost and Simple Gene Analysis Technology Developed
Professor Park Hyun Kyu of the Department of Biology and Chemical Engineering has developed a ‘real time CPR’ using Methylene Blue (nucleic acid bonding molecule with Electro-Chemical property).
The current gene analysis being used in the field is the real time PCR (Polymerase Chain Reaction) which takes advantage of the luminescent property of the gene and therefore requires expensive machines and chemicals to run.
By contrast, the electro-chemical method is easy to use and low cost and, most importantly, it allows the machine to become small and portable.
Professor Park’s research team used the decrease in the electro-chemical signal when the Methylene Blue reacts with nucleic acid and applied this to PCR which allowed for the real time analysis of the nucleic acid amplification process.
With the result of the experiment as the basis, the team was able to perform a trial with Chlamydia trachomatis, a pathogen that causes sexually transmitted disease.
The result showed that the electro-chemical method showed the same performance level as the real time PCR, which proved that the technology can be applied to diagnosing various diseases and gene research.
Ju-pyeong Lee won the Best Paper Award from IEEE RTAS
Ju-pyeong Lee, doctoral student of the Dept. of Electrical Engineering of KAIST, received the Best Paper Award from the 11th Institute of Electrical and Electronics Engineers Real-Time and Embedded Technology and Applications Symposium (IEEE RTAS) sponsored by IEEE TC on Real Time System and supported from the U.S. National Science Foundation.
He is in the Computer Engineering laboratory, and won the honor by his research of technique of Delayed Locking Technique for Improving Real-Time Performance of Embedded Linux by Prediction of Timer Interrupt. His paper was selected to be the best because of its practicality. His research purposed the technique that can dramatically improve real time problem, which was indicated to be the big problem of Linux. Moreover, he presented the way to easily materialize this technique in the practical system.
Best Paper Award is the prize awarded by IEEE Computer Society in the recognition of outstanding achievement in the field of real time system and embedded technology.
IEEE RTAS is a symposium held annually by IEEE. In this year, the 11th symposium was held from March 7 to March 10, for four days, in San Francisco, United States. The purpose of this year symposium was to seek papers describing significant contributions both to state of the art and state of the practice in the broad field of embedded and open real-time computing, control, and communication. Therefore, it especially focused on online real-time and embedded applications ranging from industrial embedded applications such as aeronautics and automotive systems to open multimedia, telecommunication and mobile computing systems.
Approximately 200 related erudite from almost 20 countries including United States, England, France, Germany, Italy, and Sweden participated in this symposium. Total number of papers submitted to IEEE RTAS was 158, while only 53 of them were selected.
by Hye-jung Won / Staff ReporterApril, 2005 / The KAIST Herald