KAIST Gives Antibodies “Eyes” to Detect Cancer, Targeting Cancer Mutations Inside Cells
Antibodies are like “guided missiles” that find and attack cancer cells, but cancer-causing mutations inside cells have remained a “blind spot” for treatment because antibodies cannot reach them. KAIST researchers have now succeeded in precisely targeting even intracellular cancer mutations using a newly designed antibody created through computational methods. This achievement is expected to open a new path toward next-generation precision therapies for difficult-to-treat cancers, going beyond the limitations of conventional antibody treatments.
KAIST (President Choongsik Bae) announced on the 24th of July that a research team led by Professor Byung-Ha Oh from the Department of Biological Sciences, together with researchers from Therazyne, a KAIST faculty startup specializing in protein design and headed by Professor Oh, has developed an antibody that selectively recognizes only cancer cells carrying KRAS(G12D), a representative cancer-driving mutation. By combining computational antibody design with experimental validation, the team designed a new antibody that would have been difficult to develop through conventional approaches and is now verifying its efficacy in animal disease models.
KRAS(G12D) is a mutated form of the KRAS protein, which regulates cell growth and proliferation. It is one of the most common cancer-driving mutations found in pancreatic, colorectal, and lung cancers. However, because the KRAS protein exists inside cells, it has long been considered an “undruggable target” that is difficult to directly target with conventional antibody therapeutics.
The research team focused on the natural process by which cells break down aged or damaged proteins into small fragments. The KRAS(G12D) protein inside cells is also processed in this way into small protein fragments, known as neoantigens, which serve as clues that allow immune cells to distinguish cancer cells. Some of these fragments are then transported to the cell surface and presented to immune cells. By combining computational protein design with experimental screening, the team developed a TCR-like antibody that precisely recognizes only this cancer-mutation-derived fragment.
TCR, or T cell receptor, acts as a “sensor” that allows T cells, the body’s immune cells, to read protein fragments displayed on the surface of cells and identify cancer cells or virus-infected cells. The TCR-like antibody developed in this study works on a similar principle, effectively giving an antibody the “eyes” of a T cell. It was designed to selectively recognize traces of intracellular cancer mutations that conventional antibodies cannot easily access.
Experimental results confirmed that the antibody developed by the team selectively recognizes only cancer cells carrying the KRAS(G12D) mutation, while showing little to no reaction with normal cells or other proteins. When applied to immunotherapy, it was also shown to effectively eliminate only cancer cells carrying the mutation. This finding suggests the possibility of expanding antibody therapy to intracellular cancer-driving proteins that conventional antibody treatments have been unable to target. It is also expected to serve as a platform technology for developing next-generation precision antibody therapies targeting not only KRAS but also a wide range of cancer mutations.
Professor Byung-Ha Oh said, “The antibody developed in this study can selectively identify only cancer cells carrying the KRAS(G12D) mutation, demonstrating the potential for precision antibody therapeutics that minimize damage to normal cells.” He added, “The computational antibody design technology developed in this research is expected to be widely applicable to the development of next-generation antibody therapeutics targeting KRAS as well as various other cancer mutations.”
Both the first author and corresponding authors of this study are KAIST-affiliated researchers. SangPhil Ahn, a researcher at Therazyne, participated as the first author, while Professor Byung-Ha Oh and Bo-Seong Jeong, Head of Research at Therazyne, jointly led the study as co-corresponding authors. The research was published online on June 3 in Molecular Therapy, a leading international journal in the field of gene and cell therapy.
Paper title: Discovery of TCR-like antibodies to the KRAS G12D neoantigen via in silico-in vitro workflow DOI: https://doi.org/10.1016/j.ymthe.2026.05.032
This research was conducted in collaboration with Therazyne and the New Drug Development Center of the Osong Biomedical Innovation Foundation, and was supported by the Ministry of Science and ICT’s Industry-Academia-Research Linked New Drug Development Program and the National Research Foundation of Korea’s Bio & Medical Technology Development Program.
A Single Blood Sample May Improve the Prediction of Colorectal Cancer Recurrence and Progression, KAIST Study Finds
A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer. A joint research team from KAIST, Gangnam Severance Hospital, and Asan Medical Center has shown that, as colorectal cancer advances, the network of relationships among circulating amino acids (a kind of metabolic map) undergoes systematic remodeling. Building on this finding, the researchers developed an analytical method that showed higher predictive performance than a CEA-only model and models based solely on individual amino acid levels.
KAIST (President Choongsik Bae) announced on July 22 that a joint research team led by Professor Ji Min Lee from the Graduate School of Medical Science and Engineering and Professor Hyunwoo Kim from the Department of Chemistry, in collaboration with researchers at Gangnam Severance Hospital and Asan Medical Center, has developed a new framework for analyzing networks of circulating amino acids, which reflect the body’s metabolic state. Using this framework, the team showed that the circulating amino acid network undergoes stage-dependent remodeling that reflects systemic metabolic reprogramming. The team then used these network-derived features to develop a new analytical strategy for predicting recurrence or metastasis.
Cancer cells require large amounts of nutrients to grow and proliferate. Amino acids are not only the building blocks of proteins but also essential for energy production and DNA synthesis, making them critical to cancer cell survival and growth. Colorectal cancer, in particular, is characterized by pronounced changes in amino acid metabolism.
These changes are not confined to tumor tissue; they also appear in the bloodstream. As a result, blood amino acids have drawn attention as an important metabolic biomarker reflecting the body's overall metabolic state. Until now, however, research has focused mainly on the concentrations of individual amino acids, leaving the question of how amino acids are interconnected and change together largely unexplored.
The team used fluorine-19 nuclear magnetic resonance (¹⁹F NMR) spectroscopy to simultaneously quantify 18 circulating amino acids in a small serum sample. By analyzing not only the relative abundance of each amino acid but also the relationships among them as a network, the researchers showed that the circulating amino acid network is progressively remodeled as colorectal cancer advances.
The researchers interpreted this remodeling as evidence of systemic metabolic reprogramming (broad changes in metabolism associated with tumor progression).
As colorectal cancer progressed, the proportion of branched-chain amino acids (BCAAs) such as valine and leucine, which play key roles in muscle and energy metabolism, decreased, while the proportion of glycine and serine, which cancer cells need to synthesize DNA and proliferate rapidly, increased. This shift suggests that systemic amino acid utilization changes with advancing disease.
Glycine proved particularly notable. Although glycine is actively used by rapidly proliferating cancer cells, its relative abundance in the blood increased rather than decreased. The team also observed the emergence of a glycine-centered interaction pattern, providing further evidence of systemic metabolic remodeling during colorectal cancer progression.
The team then applied the pairwise amino acid interaction features into machine-learning models designed to identify patients with recurrence or metastasis.
In nested cross-validation, the correlation-based model showed higher predictive performance than a CEA-only model, while the combined model incorporating CEA, individual amino acid levels, and interaction-derived features achieved the highest overall performance. It also outperformed a model based solely on individual amino acid levels.
The findings suggest that examining how amino acids interact and change together, rather than considering their levels alone, provides a more informative picture of cancer progression. The study is the first to show that the interaction network among circulating amino acids could serve as a blood-based metabolic biomarker.
"We hope this will lead to new precision medicine technologies that can predict recurrence risk more accurately using a blood sample alone and help establish personalized treatment strategies," said Professor Ji Min Lee.
The research began with an interdisciplinary idea proposed through KAIST’s Master’s and PhD Venture Research Program. Graduate students in medical science and chemistry jointly conceived an interdisciplinary approach to studying cancer progression through networks of circulating amino acids. The proposal was selected for support and ultimately led to publication in the internationally renowned journal Advanced Science.
"This research embodies the spirit of KAIST by showing how students’ creative ideas and interdisciplinary collaboration can open new possibilities,” said KAIST President Choongsik Bae. He added that KAIST will continue to foster an environment in which students and researchers can freely pursue challenges across disciplinary boundaries and support creative interdisciplinary research that produces innovative technologies contributing to public health and quality of life.
The study's co-first authors are Ji-Yeon Lee, a student in the integrated master’s and doctoral program at the Graduate School of Medical Science and Engineering, and Dr. Jumi Kim, a postdoctoral researcher in the Department of Chemistry. Professors Ji Min Lee and Hyunwoo Kim of KAIST and Professor Eun Jung Park, affiliated with Gangnam Severance Hospital and Asan Medical Center, served as co-corresponding authors. The findings were published online in Advanced Science, which has a Journal Impact Factor of 14.1, on June 9, 2026.
Paper title: Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis
DOI: 10.1002/advs.76044
This research was supported by the Samsung Research Funding & Incubation Center of Samsung Electronics, the National Research Foundation of Korea, a Faculty Research Grant from the Department of Surgery at Asan Medical Center, and grants from the Asan Institute for Life Sciences, among others.
KAIST Enables DNA Synthesis Using Only Temperature Instead of Chemical Reagents
"Complex chemical processes are essential for making DNA." This long-held assumption in the field of biotechnology has been overturned by a Korean research team. A KAIST research team has developed the world's first foundational technology that enables the synthesis of desired DNA using only temperature. Using this technology, the team also demonstrated a "DNA temperature black box" that records temperature changes during shipping without electricity.
KAIST announced on the 7th of July that a research team led by Professor Yeongjae Choi of the Graduate School of Engineering Biology, in collaboration with ATG Lifetech Inc. (CEO Taehoon Ryu) and a research team led by Professor Hansol Choi from the Department of Life Science at Ewha Womans University, has developed this platform technology that synthesizes desired DNA sequences by controlling only temperature.
DNA is the "blueprint" that contains the genetic information of humans and all other living organisms. Scientists use custom-made DNA in various biotechnology applications, such as diagnosing diseases, developing new drugs, and creating microorganisms with new functions. Until now, however, each time one of the four bases that make up DNA—A, T, G, and C—was connected, chemical reagents had to be added and washed out repeatedly. As a result, costly automated DNA synthesis equipment and specialized research facilities were essential.
To overcome these limitations, the research team developed "hairpin DNA that reacts only at specific temperatures." This hairpin DNA is a special DNA structure that remains folded like a hairpin and unfolds only at a certain temperature. The team placed multiple types of hairpin DNA that operate at different temperatures into a single test tube and succeeded in synthesizing desired DNA step by step by changing only the temperature in the sequence.
This opens the way for synthesizing DNA with only a general temperature control device, without the need for complex reagent replacement or large-scale equipment.
As the technology advances, it is expected to greatly reduce the cost and time required to make DNA, lowering the entry barriers not only for synthetic biology and genetic research, but also for various bioindustries such as drug development and precision medicine.
To demonstrate the practical applicability of the technology, the research team also implemented a power-free "DNA temperature black box." This device is normally stored in a freeze-dried state and begins operating when a single drop of water is added just before use. It then automatically records—directly into a DNA sequence—when, how long, and in what order the temperature changes during shipping. In addition, when exposed to temperatures above a certain level, the device changes color, allowing abnormalities to be checked visually on the spot. It is expected to be used for the quality control of products for which cold-chain distribution is important, such as vaccines, biopharmaceuticals, cell therapies, and fresh foods.
KAIST researcher Jangho Choi and GIST doctoral student Jinho Kim participated in this research as co-first authors, and the research results were published in the international journal Nature Communications on July 2.
※ Paper title: Programmable one-pot polymerase-mediated DNA synthesis via temperature control
※ DOI: https://doi.org/10.1038/s41467-026-74890-4
※ Related Video: https://drive.google.com/file/d/1bUtzC83qIm1k-hNFKTb09yFPhfsD4iU-/view?usp=drive_lin
※ Authors: Jangho Choi (KAIST, co-first author), Jinho Kim (GIST, co-first author), Hansol Choi (Ewha Womans University, corresponding author), Yeongjae Choi (KAIST, corresponding author)
This research was supported by the Ministry of Science and ICT through the Future Promising Convergence Technology Pioneer Program, the Biofoundry-Based Technology Development Program, the Young Researcher Program, and the Global Basic Research Laboratory Program.
KAIST presents a microbial cell factory as a source of eco-friendly food and cosmetic coloring
Despite decades of global population growth, global food crisis seems to be at hand yet again because the food productivity is cut severely due to prolonged presence of abnormal weather from intensifying climate change and global food supply chain is deteriorated due to international conflicts such as wars exacerbating food shortages and nutritional inequality around the globe. At the same time, however, as awareness of the environment and sustainability rises, an increase in demand for more eco-friendly and high-quality food and beauty products is being observed not without a sense of irony. At a time like this, microorganisms are attracting attention as a key that can handle this couple of seemingly distant problems.
KAIST (President Kwang-Hyung Lee) announced on the 26th that Kyeong Rok Choi, a research professor of the Bioprocess Research Center and Sang Yup Lee, a Distinguished Professor of the Department of Chemical and Biomolecular Engineering, published a paper titled “Metabolic Engineering of Microorganisms for Food and Cosmetics Production” upon invitation by “Nature Reviews Bioengineering” to be published online published by Nature after peer review.
※ Paper title: Systems metabolic engineering of microorganisms for food and cosmetics production
※ Author information: Kyeong Rok Choi (first author) and Sang Yup Lee (corresponding author)
Systems metabolic engineering is a research field founded by Distinguished Professor Sang Yup Lee of KAIST to more effectively develop microbial cell factories, the core factor of the next-generation bio industry to replace the existing chemical industry that relies heavily on petroleum. By applying a systemic metabolic engineering strategy, the researchers have developed a number of high-performance microbial cell factories that produce a variety of food and cosmetic compounds including natural substances like heme and zinc protoporphyrin IX compounds which can improve the flavor and color of synthetic meat, lycopene and β-carotene which are functional natural pigments that can be widely used in food and cosmetics, and methyl anthranilate, a grape-derived compound widely used to impart grape flavor in food and beverage manufacturing.
In this paper written upon invitation by Nature, the research team covered remarkable cases of microbial cell factory that can produce amino acids, proteins, fats and fatty acids, vitamins, flavors, pigments, alcohols, functional compounds and other food additives used in various foods and cosmetics and the companies that have successfully commercialized these microbial-derived materials Furthermore, the paper organized and presents systems metabolic engineering strategies that can spur the development of industrial microbial cell factories that can produce more diverse food and cosmetic compounds in an eco-friendly way with economic feasibility.
< Figure 1. Examples of production of food and cosmetic compounds using microbial cell factories >
For example, by producing proteins or amino acids with high nutritional value through non-edible biomass used as animal feed or fertilizer through the microbial fermentation process, it will contribute to the increase in production and stable supply of food around the world. Furthermore, by contributing to developing more viable alternative meat, further reducing dependence on animal protein, it can also contribute to reducing greenhouse gases and environmental pollution generated through livestock breeding or fish farming.
In addition, vanillin or methyl anthranilate, which give off vanilla or grape flavor, are widely added to various foods, but natural products isolated and refined from plants are low in production and high in production cost, so in most cases, petrochemicals substances derived from vanillin and methylanthranilic acid are added to food. These materials can also be produced through an eco-friendly and human-friendly method by borrowing the power of microorganisms.
Ethical and resource problems that arise in producing compounds like Calmin (cochineal pigment), a coloring added to various cosmetics and foods such as red lipstick and strawberry-flavored milk, which must be extracted from cochineal insects that live only in certain cacti. and Hyaluronic acid, which is widely consumed as a health supplement, but is only present in omega-3 fatty acids extracted from shark or fish livers, can also be resolved when they can be produced in an eco-friendly way using microorganisms.
KAIST Research Professor Kyeong Rok Choi, the first author of this paper, said, “In addition to traditional fermented foods such as kimchi and yogurt, foods produced with the help of microorganisms like cocoa butter, a base ingredient for chocolate that can only be obtained from fermented cacao beans, and monosodium glutamate, a seasoning produced through microbial fermentation are already familiar to us”. “In the future, we will be able to acquire a wider variety of foods and cosmetics even more easily produced in an eco-friendly and sustainable way in our daily lives through microbial cell factories.” he added.
< Figure 2. Systems metabolic engineering strategy to improve metabolic flow in microbial cell factories >
Distinguished Professor Sang Yup Lee said, “It is engineers’ mission to make the world a better place utilizing science and technology.” and added, “Continuous advancement and active use of systems metabolic engineering will contribute greatly to easing and resolving the problems arising from both the food crisis and the climate change."
This research was carried out as a part of the “Development of Protein Production Technology from Inorganic Substances through Control of Microbial Metabolism System Project” (Project Leader: Kyeong Rok Choi, KAIST Research Professor) of the the Center for Agricultural Microorganism and Enzyme (Director Pahn-Shick Chang) supported by the Rural Development Administration and the “Development of Platform Technologies of Microbial Cell Factories for the Next-generation Biorefineries Project” (Project Leader: Sang Yup Lee, KAIST Distinguished Professor) of the Petroleum-Substitute Eco-friendly Chemical Technology Development Program supported by the Ministry of Science and ICT.
Two Professors Recognized for the National R&D Excellence 100
< Professor Haeng-Ki Lee (left) and Professor Jeong-Ho Lee (right) >
Two KAIST professors were listed among the 2019 National R&D Excellence 100 announced by the Ministry of Science and ICT and the Korea Institute of S&T Evaluation and Planning.
Professor Haeng-Ki Lee from the Department of Civil and Environmental Engineering was recognized in the field of mechanics and materials for his research on developing new construction materials through the convergence of nano- and biotechnologies.
In the field of life and marine science, Professor Jeong-Ho Lee from the Graduate School of Medical Science and Engineering was lauded for his research of diagnostic tools and therapies for glioblastoma and pediatric brain tumors.
A certificate from the Minister of Ministry of Science and ICT will be conferred to these two professors, and their names will be inscribed on a special 2019 National R&D Excellence 100 plaque to celebrate their achievements. The professors will also be given privileges during the process of new R&D project selection.
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Novel Via-Hole-Less Multilevel Metal Interconnection Methods
Forming reliable multi-level metal interconnections is a key technology for integrating devices into organic integrated circuits (ICs). The conventional approach, called “via-hole,” locally removes the insulator and utilizes metal interconnects through the holes. Due to the high sensitivity of organic materials to chemical solvents, heat, and photo-radiation used in conventional “via-hole” methods, alternative printing methods or laser drilling methods have been developed. However, finding a reliable and practical metal interconnection for organic ICs is still challenging.
The research team of KAIST Professor Sung Gap Im and Postech Professor Kim Jae-Joon reported a new interconnection method that does not require via-hole formation, “via-hole-less metal interconnection,” in Nature Communications on June 3.
Metal electrodes in different layers can be isolated from each other by patterned dielectric layers, where they then can be interconnected to others in the open area where the dielectric layer is not present. See the images below. Vapor phase deposition and in-situ patterning of dielectric layer using iCVD (initiated chemical vapor deposition), used in the “via-hole-less” method, ensure a damage-free process for organic semiconductor materials and result in outstanding performance of the organic devices as multilevel metal interconnects are reliably formed. The team successfully demonstrated three-dimensional (3D) stacking of five organic transistors and integrated circuits using the proposed via-hole-less interconnect method. See the image below.
Vapor phase deposition and in-situ patterning of dielectric layer using iCVD (initiated chemical vapor deposition), used in the “via-hole-less” method, ensure a damage-free process for organic semiconductor materials and result in outstanding performance of the organic devices as multilevel metal interconnects are reliably formed. The team successfully demonstrated three-dimensional (3D) stacking of five organic transistors and integrated circuits using the proposed via-hole-less interconnect method. See the image below.
Professor Kim explained, “Our proposed via-hole-less interconnect method using a selectively patterned dielectric overcomes the limitations of the previous time-consuming, one-by-one via-hole formation process and provides reliable methods for creating metal interconnects in organic ICs. We expect the via-hole-less scheme to bring advances to organic IC technology.”
Meditox Donates 600 Million KRW Scholarship
On February 17, a Korean biopharmaceutical company Meditox, headed by Chief Executive Officer (CEO) Hyun-Ho Jeong, signed a memorandum of understanding (MOU) with KAIST to establish the “Meditox Fellowship” and donated a total of 600 million Korean won (KRW) to the university to assist in promoting more scientists in the field of biology.
Meditox CEO Hyun-Ho Jeong, KAIST President Steve Kang, Dean of Life Science and Bioengineering College Jung-Hoe Kim, and Dean of the Department of Biological Sciences Byung-Ha Oh participated in the agreement ceremony.
According to the MOU, Meditox will donate 60,000,000 KRW over a ten year period, from which KAIST can draw on to grant scholarships for master’s and doctoral students.
The “Meditox Fellowship” will support promising and enthusiastic students whose finances limit their studies. The first scholarship students for 2016 were: Kwang-Uk Min, In-suk Yeo, Sung-ryung- Lee, Si-on Lee, and Jung-hyun Kim.
Meditox CEO Jeong, who graduated from KAIST’s Department of Biological Sciences, said, "I felt it was important to start the Meditox Fellowship at my alma mater to contribute to the cultivation of outstanding scientists in the field of biological sciences."
He also said that he would plan to launch projects that aim to support not only those who receive the scholarship but also the development of Korea’s biological sciences in general.
President Steve Kang (right) and Chief Executive Officer Hyun-Ho Jeong (left) of Meditox hold the signed memorandum of understanding together.
Professor Ki-Jun Jeong Wins the 2015 Dam Yeun Academic Award
The 11th Dam Yeun Academic Award presented by the Korean Society for Biotechnology and Bioengineering (KSBB) to a biologist under 45 years old went to Professor Ki-Jun Jeong of the Chemical and Biomolecular Engineering Department at KAIST.
The award ceremony took place on October 13, 2015, at the annual conference of KSBB held at Songdo Convensia in Incheon City.
Each year KSBB announces the recipient of the award based on the publications by researchers in the last five years at peer-reviewed international journals or KSBB Journal as well as the record of patent registration and technology transfers.
Professor Jeong is recognized for his pioneering research in protein, antibody, cellular engineering, and protein displays and chips.
Professor Ki Jun Jeong Selected As the Winner of the 'Young Asian Biotechnologist Prize'
Professor Ki Jun Jeong from the Department of Chemical and Biomolecular Engineering, KAIST, has been selected as the winner of this year’s Young Asian Biotechnologist Prize.
Professor Jeong was invited to the 66th Japan Biotechnology and Bioengineering Society Conference scheduled in September 9th-11th, 2014, in Sapporo, Japan, where his award ceremony will be held.
The award is presented to Professor Jeong in recognition of his outstanding research on microbial-based production of antibodies and efficiency improvement.
The Young Asian Biotechnologist Prize is awarded annually by the Japan Biotechnology and Bioengineering Society to the researchers in Asia under the age of 45, who have achieved excellent research results in the field of bioengineering.
Professor YongKeun Park Produces Undergraduate Students with International Achievements
Three undergraduate students under the supervision of Professor YongKeun Park from the Department of Physics, KAIST, have published papers in globally renowned academic journals.
The most recent publication was made by YoungJu Jo, a senior in physics. Jo’s paper entitled “Angle-resolved light scattering of individual rod-shaped bacteria based on Fourier transform light scattering” was published in the May 28th edition of Scientific Reports.
Analyzing bacteria is a very important task in the field of health and food hygiene, but using the conventional biochemical methods of analysis takes days. However, observation with Jo’s newly developed method using light scattering analyzes bacteria within a matter of seconds.
SangYeon Cho from the Department of Chemistry also published papers in Cell (2012) and Nature (2013), respectively, under the guidance of Professor Park. SangYeon Cho’s outstanding research achievements were recognized by Harvard and MIT. He was accepted with a full scholarship to Harvard-MIT Health Sciences and Technology Graduate School. He will begin his graduate studies at Harvard-MIT this September.
Last March, SeoEun Lee from the Department of Biology was the recipient of the Best Paper Award by the Optical Society of Korea. She plans to pursue a doctoral degree at the College of Physicians and Surgeons, Columbia University in New York.
Professor Park said, “Undergraduate students, who are learning a variety of subjects concurrently, are at the most creative time of their lives. KAIST has offered many opportunities to undergraduate students to partake in various research programs.”
- Picture (a) and (b): Rod-shaped bacteria’s phase image and light-scattering patterns
- Picture (c): Quantitative analysis to illustrate the extraction of information from bacteria
Distinguished Professor Sang Yup Lee appointed as an advisor for Shanghai Jiao Tong University in China
In recognition of his outstanding accomplishments in the area of bioengineering, specializing in metabolic engineering, Sang Yup Lee, a distinguished professor of Chemical & Biomolecular Engineering at KAIST, was assigned as an advisory professor for the bioengineering department at Shanghai Jiao Tong University in China for five years from August 2013 to July 2018.
Together with Peking University and Tsinghua University, Shanghai Jiao Tong University is one of the top three universities in China.
The advisory professors carry out collaborated research programs in special areas and provide advice on education and research issues.
Professor Lee, a specialist in metabolic engineering, has initiated systems metabolic engineering which integrates metabolic engineering, systems biology, and synthetic biology and has applied it to various chemical production systems to develop bio fuel and many eco-friendly chemical production processes. Recently, he received the Marvin J. Johnson Award from the American Chemistry Society, the Charles Thom Award from the American Society for Industrial Microbiology, as well as the Amgen Biochemical Engineering Award. As a global leader in the area of bioengineering, Professor Lee is a member of the Korean Academy of Science & Technology, the National Academy of Engineering of Korea, the US National Academy of Engineering, and is the chairman of the Global Agenda Council on Biotechnology at the World Economic Forum.
Ph.D. students Hyowon Park and Won Ma receive Grand Prizes in Mathematics and Biology respectively.
Researchers in KAIST received best paper awards in two out of three fields at this year’s award ceremony for the “Second Annual Best Thesis Paper Award” held collectively by the Korea University Presidents’ Federation (with Chairman DaeSoon Lee) and the Korean Academy of Science and Technology (with Director GilSang Jung).
Two researchers from KAIST, Hyowon Park (Department of Mathematics) and Won Ma (Department of Biology) received best paper awards.
This prize, given by the both the Korea University Presidents’ Federation and the Korean Academy of Science and Technology since last year, is awarded to researchers and assistant professors who write the most outstanding thesis papers in the field of basic sciences.
Park, who received the best paper award this year, did research on graph braid groups. He was supervised by Professor Kihyung Ko, who received the best supervisor reward.
Ma, who received the best paper award in the field of biological science, researched about the Attention Deficit/Hyperactivity Disorder due to deficiency of the GIT1 synapse protein. His supervising professor also received the supervisor award.
The award ceremony was held in the auditorium of the S-OIL headquarters in Seoul on November 30.
Meanwhile, NASA researcher Jaehwa Lee received the best paper award in the field of earth science, and his supervising professor, Professor Jun Kim from Yonsei University who studies atmospheric science, received the best supervisor award.