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Professor Jeong Ho Lee Receives the 2015 Pediatric Epilepsies Research Award
The award identifies leading scientists worldwide and funds their cutting-edge research in epilepsy. The Citizen United for Research in Epilepsy (CURE) announced on September 7, 2015, that Jeong Ho Lee, a professor of the Graduate School of Medical Science and Engineering at KAIST, will be awarded the 2015 Pediatric Epilepsies Research Award. The Pediatric Epilepsies Research Award is given annually to a researcher who has conducted novel, innovative research projects that address severe, intractable pediatric epilepsies as well as collaborative, interdisciplinary projects that explore new approaches to find a treatment for pediatric epilepsies. Lee was recognized for his leading study in the field of intractable epilepsy. He is the first Korean who has ever received this award, securing a research grant of USD 250,000 for two years. Lee has conducted research on brain somatic mutations as the novel cause of childhood intractable epilepsy. Pediatric epilepsies account for approximately 70% of all cases of epilepsy. Established in 1998, CURE is a non-profit American organization based in Chicago, Illinois, which is committed to funding research and various initiatives that will lead to breakthroughs to cure epilepsy. Since its inception, CURE has been at the forefront of epilepsy research, raising more than USD 32 million to support researchers and scientists worldwide. It has also awarded more than 180 cutting-edge projects in 13 countries.
2015.09.09
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The Journal of Clinical Investigation: Researchers Uncover the Secret Lymphatic Identity of the Schlemm's Canal
The Journal of Clinical Investigation (JCI), a peer-reviewed, top-tier medical journal published by the American Society for Clinical Investigation, carried a commentary entitled “Schlemm’s Canal: More Than Meets the Eye, Lymphatics in Disguise” in the July 25, 2014 issue. In the commentary, the authors compared a research paper (“Lymphatic regular PROX1 determines Schlemm’s canal integrity and identity”) by Professor Gou-Young Koh of the Graduate School of Medical Science and Engineering at KAIST with research work from the University of Helsinki (article entitled “The Schlemm’s canal is a VEGF-C/VEGFR-3 responsive lymphatic-like vessel”). The JCI released a press statement dated July 25, 2014 on its commentary. It mentioned that glaucoma, one of the leading causes of blindness worldwide, elevates eye pressure owing to poor drainage of aqueous humor. A specialized structure called “Schlemm’s canal” funnels aqueous humor from the eye back into circulation, which is critical to prevent pressure buildup in the eye. The article discussed the role of Schlemm’s canal in the context of lymphatic vascular characteristics by reviewing two research group’s papers back-to-back. For the full text of the press release, please visit the link below: Press Release from the Journal of Clinical Investigation, July 25, 2014 “Researchers uncover the secret lymphatic identity of the Schlemm’s canal” http://www.eurekalert.org/pub_releases/2014-07/joci-rut072414.php
2014.07.28
View 6876
Seo-Eun Lee, an undergaruate student receives the Best Paper Award from Optical Society of Korea
Seo-Eun Lee, a student studying at KAIST’s Department of Biological Sciences, has won the Best Paper Award from Bio-Photonics Division at the 2014 Optical Society of Korea Winter Conference, held on 19th February at Daejeon Convention Center. Only one outstanding paper per division is given an award among the total of 270 papers, and it is very unusual for an undergraduate student to win the award in the field that is not her major. Lee has studied cell imaging using holography technology since June 2013 under the supervision of Professor Yong-Geun Park from the Department of Physics. The Optical Society of Korea was founded in 1989, and as the largest academy in the field of optics in Korea, it holds academic presentations, seminars and lectures every year.
2014.03.06
View 7913
Professor Kim Eun Joon receives In Chon Award
Professor Kim Eun Joon (Department of Biological Sciences) received the In Chon Awarded hosted by In Chon Memorial and Dong Ah Newspaper. The Award Ceremony will be held on the 8th of October in Seoul Lotte Hotel and Professor Kim will be given a medal and prize money amounting 100million Korean Won. Professor Kim is a world renowned research in the field of Synapses. Professor Kim graduated from the Department of Pharmacy in Pusan University, B.A. at KAIST, and Ph.D at Michigan University. He has been a Professor at KAIST since 2000.
2012.09.11
View 6920
'Scientist-Engineer of the Month' for December: Professor Choi Joon Ho
Professor Choi Joon Ho (department of Biological Sciences) was made ‘Scientist-Engineer of December’ for his discovery of new gene (twenty-four) that helps biorhythm and proving that this gene helps control biorhythm. Professor Choi published 100 dissertations over the past 25 years and made significant advancements in the field of molecular virus and neurobiology. In 1995 Professor Choi uncovered the fact that the NS3 protein in C type hepatitis function as RNA helicase thereby opening the path to developing a cure for C type hepatitis; this is an international patent with Chiron corporation. The result was published in Biochemical and Biophysical Research Communications Journal and was the most domestically referred to dissertation in biological sciences in 1999. In addition Professor Choi published in Nature magazine in 1999, a dissertation that uncovered the fact that the DNA of papillomar virus has another protein (hSNF5) that direct it apart from ordinary proteins. In 2000~2005 Professor Choi published many dissertations in journals like Immunity, Cancer Research, Molecular and Cellular Biology, Oncogene, Journal of Virology, and etc. Professor Choi screened over 10,000 species of pomace fly mutations and discovered the twenty-four gene that affects the biorhythm of pomace flies. He analyzed this gene further and found a new function that was different from known biorhythm mechanisms. This research allowed a better understanding of biological clock of pomace flies and therefore was another step towards better understanding the control mechanism of human biological clock.
2012.01.31
View 7595
Biomimetic Carbon Nanotube Fiber Synthesis Technology Developed
The byssus of the mussel allows it to live in harsh conditions where it is constantly battered by crashing waves by allowing the mussel to latch onto the seaside rocks. This particular characteristic of the mussel is due to the unique structure and high adhesiveness of the mussel’s byssus. KAIST’s Professor Hong Soon Hyung (Department of Material Science and Engineering) and Professor Lee Hae Shin (Department of Chemistry) and the late Professor Park Tae Kwan (Department of Bio Engineering) were able to reproduce the mussel’s byssus using carbon nanotubes. The carbon nanotube, since its discovery in 1991, was regarded as the next generation material due to its electrical, thermal, and mechanical properties. However due to its short length of several nanometers, its industrial use was limited. The KAIST research team referred to the structure of the byssus of the mussel to solve this problem. The byssus is composed of collagen fibers and Mefp-1 protein which are in a cross-linking structure. The Mefp-1 protein has catecholamine that allows it to bind strongly with the collagen fiber. In the artificial structure, the carbon nanotube took on the role of the collagen fibers and the macromolecular adhesive took on the role of the catecholamine. The result was a fiber that was ultra-light and ultra-strong. The results of the experiment were published in the Advanced Materials magazine and is patent registered both domestically and internationally.
2011.06.20
View 10151
Research Conducted on the Development Policy of Medical Researchers in United States
The topic dealt in the paper was “The Vietnam War and Medical Research: Untold Legacy of the U.S. Doctor Draft and the NIH ‘Yellow Berets’” and basically deals how a Doctor Draft made a positive impact on improving the basic research of clinical medicine. Professor Park received his Doctorate at Johns Hopkins University and came to KAIST in 2007. Summary of Dissertation From the start of the Korean War in 1950 to the end of the Vietnam War in 1973 a large number of medical school graduates were drafted to the army. Of those drafted, 100 personnel were chosen annually to focus on researching in the National Institute of Health who developed into leaders of the field. For example, those who worked as a researcher at the National Institute instead of their armed services were 1.5 times more likely to become a tenured professor, 2 times more likely to be promoted to Dean of the department, and 3 times more likely to be the Dean. In addition, 9 out of 50 Nobel Prize winners in fields of natural sciences between 1985 and 2007 were from the same pool of researchers, and 10 out of 76 recipients of National Medal of Science were also from the same pool of researchers. They were named the ‘Yellow Berets’ like the special forces ‘Green Berets’ and made great contribution to the field in implementing and executing the bench to beside culture that involves development in laboratories to clinical testing. Professor Park maintains that there has to be improvements made in current policies to encourage research work in medical graduate schools.
2011.05.31
View 9279
Genetic Cause of ADHD (Attention Deficit Hyperactivity Disorder) Found
The cooperative research team consisting research teams under Professor Kim Eun Joon and Professor Kang Chang Won of the department of Biological Sciences discovered that ADHD arises from the deficiency of GIT1 protein in the brain’s neural synapses. ADHD (Attention Deficit Hyperactivity Disorder) is found in around 5% of children around the world and is a disorder where the child becomes unable to concentrate, show over the top responses, and display impulsive behavior. The research team found that the difference between children with ADHD and those without it is one base in the GIT1 gene. The difference of a single base causes the underproduction of this protein, and those children with low levels of the protein had a higher probability to develop ADHD. In addition, further evidence was provided when the research team conducted mice experiments. Those mice with low levels of GIT1 exhibited impulsive and exaggerated reactions like humans with ADHD, had learning disabilities, and produced abnormal brain waves. And upon injecting these mice with cure for ADHD, the symptoms of ADHD disappeared. The impulsive behavior of ADHD children disappears as the child enters adulthood and a similar pattern was found in mice. A mice with low levels of GIT1 showed impulsive behaviors when 2 months old, but these behaviors disappeared as it got older to around 7 months old (equivalent to 20~30 years old for humans). Professor Kim Eun Joon commented that there has to be equilibrium between mechanisms that excite the neurons and mechanisms that calm the neurons, but the lack of GIT1 leads to the decrease in the mechanisms that calm the neurons which causes the impulsive behavior of ADHD patients. In addition, Professor Kang Chang Won commented that the results of the experiment has been receiving rave reviews and is being seen as the new method in the production of the cure for ADHD. The result of the experiment was published in the online edition of Nature Medicine magazine.
2011.04.30
View 8667
Professor Ko Kyu Young Appointed as a Distinguished Professor at KAIST
Professor Ko Kyu Young of the Graduate School of Medical Sciences was appointed as the Distinguished Professor at KAIST. Professor Ko is famous internationally for his work on the catalyst for blood vessel growth COMP-ANG1, and also for his research on blood vessel growth and lymph duct growth control. Professor Ko developed the Double Anti-Angiogenic Protein (DAAP) which effectively restricts the blood vessels from growing, opening a new approach to curing caner. The paper was published in ‘Cancer Cell’ as the cover paper (2010 August 17th edition) and is widely recognized as the marker that sums up the new paradigm of cure for cancer. In addition, his work on explaining how the new antigen interacts with the T-lymphocyte during a vaccination lead to the possibility of the increase of the efficiency of vaccination. The result of the research was published as the cover paper in ‘Immunity’ magazine. As is obvious to see his work with blood vessel growth and lymph duct growth and control is being published in major scientific journals. In addition he is continuously invited to international conferences as guest speakers and leader, effectively leading the field. As a result, he was appointed as the editor of ‘Blood’ magazine, the world’s best journal in the field of hematology and received ‘2010 KAISTian of the Year’ Award. The title Distinguished Professor is appointed to those who have made world-class research results and educational results and actively lead their respective field. They are provided with extra incentives and can even continue on with the professorship after retirement. It is only limited to 3% of the professors at KAIST and has to be someone recommended by the President, Vice-President, and the Deans of department and their worthiness is scrutinized by a foreign expert.
2011.03.25
View 9174
New Bio-Clock gene and its function found
The Ministry of Education, Science and Technology announced that a Korean research team has found a new gene responsible for maintaining the bio-clock (twenty-four) and its mechanism. Twnety-four was led by Professor Choi Joon Ho and Dr. Lee Jong Bin of KAIST (department of Biology) and was a joint operation with Professor Ravi Allada and Dr.Lim Jeong Hoon of Northwestern University (department of neurobiology) and the result was published in ‘Nature’ magazine. The research team experimented with transformed small fruit flies for 4 years and found that there was an undiscovered gene that deals with the bio rhythm in the brain which they named ‘twenty-four’. The understanding with genes prior to twenty-four was that these genes regulate biorhythm in the transcription phase (DNA to mRNA). Twenty-four operates in the step after transcription when the ribosome creates proteins. Especially twenty-four has a great effect on the ‘period protein’ which acts as a sub-atomic clock that regulates the rhythm and life of each cell. The experiment was innovational in that it was able to scientifically prove the function of the protein produced by the gene. The result is expected to help solve the problems associated with sleep disorders, jetlags, eating rhythms, bio rhythms, etc. The name twenty-four was the fact that a day, a cycle, is 24 hours long and the gene’s serial numbers CG4857 adds up to twenty four.
2011.02.23
View 9516
College of Cultural Science selects 'Best English Paper' Recipients
KAIST’s College of Cultural Science (Dean Kim Dong Won) announced the winners of ‘2010 Fall Semester Best English Paper Award’: Excellence Award went to Kwak Ah Young (department of Biology), Seong Du Hyun (undeclared major), Ahn Da In (Biological Chemical Engineering), and nine other students received the Participation Award. Ahn Da In discussed ‘Joyce and Chopin on use of epiphany’, Seong Du Hyun discussed ‘On Kant’s Groundwork for the metaphysics of Morals, its Achievements, and Implications’, and Kwak Ah Young discussed ‘Fact Pattern of Environmental Law’. The ‘Best English Paper’ Award has been awarded to undergraduates since 2009 Fall semester in the Humanities and Social Science Department’s efforts to increase creativity and English writing skills of students attending KAIST. For the 2010 fall semester, each professor in charge went through 1 to 2 papers (among 610 papers admitted across human science subjects) and recommended 29 papers to be discussed with great scrutiny. The evaluation took place throughout January and the 3 papers discussing English Literature, Scientific Philosophy, and Environmental Law were awarded the Excellence Award, and 9 other papers were awarded the Participation Award. Dean of Cultural Science College Kim Dong Won commented, ‘I am very encouraged by the level of papers and is becoming a very large art of the College of Cultural Science’. The chairman of the screening committee, Professor Kim Eun Kyung also commented, ‘the best paper award is helping students better their English levels’ and that ‘in order to form and encourage a sound and structured English paper writing environment, a anti-plagiarism program will be implemented amongst implementing other judging standards’.
2011.02.21
View 9002
The 40th Anniversary of the Establishment of KAIST Commemoration Held
KAIST, aspiring to become the best Science and Technology University, has turned 40. KAIST held the commemoration ceremony for the 40th Anniversary of the Establishment of KAIST in the auditorium. Five awards (Scholar, Creative Lecture, Excellence in Lecture, International Cooperation, Experiment) were given to Professors Kim Eun Jun and Walton Jones (department of Biology), Professor Abigail Shin (department of Humanities and Social Sciences), Professor Shin Seong Chul (department of Physics), and Professor Lee Sang Yeop (department of Biological Chemical Engineering). Each recipient received a prize of five million won. Professor Song Joon Hwa (department of Computer Sciences) received the ‘New Knowledge Award’ in recognition of his development of the Orchestrator Mobile platform. The new platform is different from Android or the IOS platform in that it allows a fluid relationship to be formed between the smartphone and the user. KAIST also showed off its new emblem. The emblem consists of a star which represents the KAIST’s goals of becoming the world leader, of training leaders, the center point, and hope. The main keywords are: ‘Leadership’, ‘Premium’, ‘Scientific’, and ‘Humanity’. KAIST plans on having various events from May 9th when there will be the Vision Declaration.
2011.02.21
View 10972
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